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PMC:7195088 / 67202-68210 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
1952 255-263 Species denotes patients Tax:9606
1953 311-319 Species denotes patients Tax:9606
1954 740-748 Species denotes patients Tax:9606
1955 935-943 Species denotes patients Tax:9606
1956 956-964 Species denotes patients Tax:9606
1957 20-31 Chemical denotes chloroquine MESH:D002738
1958 32-50 Chemical denotes hydroxychloroquine MESH:D006886
1959 438-456 Chemical denotes hydroxychloroquine MESH:D006886
1960 617-624 Chemical denotes steroid MESH:D013256
1961 828-835 Chemical denotes steroid MESH:D013256
1962 275-301 Disease denotes respiratory tract symptoms MESH:D012140
1963 331-357 Disease denotes respiratory tract symptoms MESH:D012140
1964 715-729 Disease denotes critically ill MESH:D016638
1965 735-739 Disease denotes ARDS MESH:D012128
1966 930-934 Disease denotes ARDS MESH:D012128
1967 951-955 Disease denotes ARDS MESH:D012128

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T116 269-292 Body_part denotes upper respiratory tract http://purl.org/sig/ont/fma/fma45661
T117 325-348 Body_part denotes lower respiratory tract http://purl.org/sig/ont/fma/fma45662

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T51 269-292 Body_part denotes upper respiratory tract http://purl.obolibrary.org/obo/UBERON_0001557
T52 275-292 Body_part denotes respiratory tract http://purl.obolibrary.org/obo/UBERON_0000065
T53 325-348 Body_part denotes lower respiratory tract http://purl.obolibrary.org/obo/UBERON_0001558
T54 331-348 Body_part denotes respiratory tract http://purl.obolibrary.org/obo/UBERON_0000065

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T383 735-739 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T384 930-934 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T385 951-955 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T369 166-171 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T370 210-212 http://purl.obolibrary.org/obo/CLO_0053794 denotes 41
T371 230-231 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T372 325-348 http://purl.obolibrary.org/obo/UBERON_0001558 denotes lower respiratory tract
T373 411-412 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T374 670-671 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T375 783-784 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T87596 20-31 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T51549 32-50 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T54232 55-70 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T33985 238-243 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T99 438-456 Chemical denotes hydroxychloroquine http://purl.obolibrary.org/obo/CHEBI_5801
T38634 617-624 Chemical denotes steroid http://purl.obolibrary.org/obo/CHEBI_35341
T95699 828-835 Chemical denotes steroid http://purl.obolibrary.org/obo/CHEBI_35341

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T473 0-104 Sentence denotes The optimal time of chloroquine/hydroxychloroquine and corticosteroids initiation still remains unknown.
T474 105-601 Sentence denotes Although based on low-level evidence, the positive effect of virus clearance observed by Gautret et al. [41] was observed in a mixed group of non-ICU patients with upper respiratory tract symptoms, non-ICU patients with lower respiratory tract symptoms and asymptomatic subjects, which overall may support a positive effect of early hydroxychloroquine initiation in non-ICU settings (although information on the exact time of treatment initiation with respect to symptoms onset was not provided).
T475 602-749 Sentence denotes With regard to steroid treatment, there is currently no evidence of a positive impact of early initiation in non–critically ill, non-ARDS patients.
T476 750-1008 Sentence denotes Although lack of evidence is not a synonym of lack of effect, in our opinion, steroid treatment, considering also its potential detrimental effects, should currently be limited to ARDS patients or non-ARDS patients with worsening conditions (see question 5).