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PMC:7195088 / 60242-61274 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
1803 139-147 Species denotes patients Tax:9606
1804 316-324 Species denotes patients Tax:9606
1805 330-340 Species denotes SARS-CoV-2 Tax:2697049
1806 525-533 Species denotes patients Tax:9606
1807 652-660 Species denotes patients Tax:9606
1808 1023-1031 Species denotes patients Tax:9606
1809 897-904 Chemical denotes steroid MESH:D013256
1810 969-976 Chemical denotes steroid MESH:D013256
1811 153-173 Disease denotes SARS-CoV-2 infection MESH:C000657245
1812 381-393 Disease denotes inflammation MESH:D007249
1813 415-426 Disease denotes lung injury MESH:D055370
1814 476-485 Disease denotes pneumonia MESH:D011014
1815 516-524 Disease denotes COVID-19 MESH:C000657245
1816 628-642 Disease denotes critically ill MESH:D016638
1817 643-651 Disease denotes COVID-19 MESH:C000657245
1818 666-670 Disease denotes ARDS MESH:D012128
1819 696-720 Disease denotes ARDS respiratory failure MESH:D012131
1820 995-1013 Disease denotes non–critically ill MESH:D016638
1821 1014-1022 Disease denotes COVID-19 MESH:C000657245

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T95 398-406 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T96 415-419 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T49 415-419 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T101 476-485 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T102 701-720 Phenotype denotes respiratory failure http://purl.obolibrary.org/obo/HP_0002878

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T344 153-161 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T345 164-173 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T346 330-338 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T347 381-393 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T348 420-426 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T349 476-485 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T350 516-524 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T351 643-651 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T352 666-670 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T353 696-700 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T354 701-720 Disease denotes respiratory failure http://purl.obolibrary.org/obo/MONDO_0021113
T355 1014-1022 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T332 195-207 http://purl.obolibrary.org/obo/OBI_0000245 denotes Organization
T333 415-419 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T334 415-419 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T7997 106-120 Chemical denotes corticosteroid http://purl.obolibrary.org/obo/CHEBI_50858
T21891 289-304 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T62412 609-624 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T11802 897-904 Chemical denotes steroid http://purl.obolibrary.org/obo/CHEBI_35341
T65 969-976 Chemical denotes steroid http://purl.obolibrary.org/obo/CHEBI_35341

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T29 381-393 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T440 0-20 Sentence denotes Question 5 statement
T441 21-174 Sentence denotes So far, no definitive efficacy or effectiveness data are available on the benefit of corticosteroid administration in patients with SARS-CoV-2 infection.
T442 175-341 Sentence denotes As the World Health Organization underlines, there is an important need for efficacy data from RCT for supporting corticosteroids therapy in patients with SARS-CoV-2.
T443 342-803 Sentence denotes However, considering that overwhelming inflammation and cytokine-related lung injury might be responsible for the rapidly progressive pneumonia and clinical deterioration in COVID-19 patients [44,58,67], we suggest (expert opinion only) to consider administration of corticosteroids in critically ill COVID-19 patients with ARDS or with worsening of non-ARDS respiratory failure in the absence of bacterial/fungal superinfections (independent of ICU admission).
T444 804-1032 Sentence denotes However, in the absence of convincing evidence, the following cannot currently be supported: steroid administration stratified according to inflammatory markers and steroid administration in non–critically ill COVID-19 patients.

2_test

Id Subject Object Predicate Lexical cue
32360444-31986264-22369807 535-537 31986264 denotes 44
32360444-22088618-22369808 538-540 22088618 denotes 58
32360444-32192578-22369809 541-543 32192578 denotes 67