PMC:7195088 / 5826-6230 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7195088","sourcedb":"PMC","sourceid":"7195088","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7195088","text":"CT does not support off-label treatment with LPV/RTV in COVID-19 patients. This result should also discourage the use of other protease inhibitors (e.g. darunavir), at least until results of dedicated RCT are available. Although promising in preclinical studies, remdesivir should be currently provided to COVID-19 patients only within RCT (preferentially) or compassionate-use/expanded-access programmes","tracks":[{"project":"LitCovid-PubTator","denotations":[{"id":"155","span":{"begin":65,"end":73},"obj":"Species"},{"id":"156","span":{"begin":315,"end":323},"obj":"Species"},{"id":"190","span":{"begin":45,"end":52},"obj":"Chemical"},{"id":"191","span":{"begin":153,"end":162},"obj":"Chemical"},{"id":"192","span":{"begin":263,"end":273},"obj":"Chemical"},{"id":"215","span":{"begin":56,"end":64},"obj":"Disease"},{"id":"216","span":{"begin":306,"end":314},"obj":"Disease"}],"attributes":[{"id":"A155","pred":"tao:has_database_id","subj":"155","obj":"Tax:9606"},{"id":"A156","pred":"tao:has_database_id","subj":"156","obj":"Tax:9606"},{"id":"A190","pred":"tao:has_database_id","subj":"190","obj":"MESH:C558899"},{"id":"A191","pred":"tao:has_database_id","subj":"191","obj":"MESH:D000069454"},{"id":"A192","pred":"tao:has_database_id","subj":"192","obj":"MESH:C000606551"},{"id":"A215","pred":"tao:has_database_id","subj":"215","obj":"MESH:C000657245"},{"id":"A216","pred":"tao:has_database_id","subj":"216","obj":"MESH:C000657245"},{"subj":"155","pred":"source","obj":"LitCovid-PubTator"},{"subj":"156","pred":"source","obj":"LitCovid-PubTator"},{"subj":"190","pred":"source","obj":"LitCovid-PubTator"},{"subj":"191","pred":"source","obj":"LitCovid-PubTator"},{"subj":"192","pred":"source","obj":"LitCovid-PubTator"},{"subj":"215","pred":"source","obj":"LitCovid-PubTator"},{"subj":"216","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T24","span":{"begin":56,"end":64},"obj":"Disease"},{"id":"T25","span":{"begin":306,"end":314},"obj":"Disease"}],"attributes":[{"id":"A24","pred":"mondo_id","subj":"T24","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A25","pred":"mondo_id","subj":"T25","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"subj":"T24","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T25","pred":"source","obj":"LitCovid-PD-MONDO"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T21","span":{"begin":24,"end":29},"obj":"http://purl.obolibrary.org/obo/CLO_0007225"}],"attributes":[{"subj":"T21","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T16","span":{"begin":24,"end":29},"obj":"Chemical"},{"id":"T17","span":{"begin":127,"end":146},"obj":"Chemical"},{"id":"T19","span":{"begin":136,"end":146},"obj":"Chemical"},{"id":"T20","span":{"begin":153,"end":162},"obj":"Chemical"},{"id":"T21","span":{"begin":263,"end":273},"obj":"Chemical"}],"attributes":[{"id":"A16","pred":"chebi_id","subj":"T16","obj":"http://purl.obolibrary.org/obo/CHEBI_35209"},{"id":"A17","pred":"chebi_id","subj":"T17","obj":"http://purl.obolibrary.org/obo/CHEBI_37670"},{"id":"A18","pred":"chebi_id","subj":"T17","obj":"http://purl.obolibrary.org/obo/CHEBI_60258"},{"id":"A19","pred":"chebi_id","subj":"T19","obj":"http://purl.obolibrary.org/obo/CHEBI_35222"},{"id":"A20","pred":"chebi_id","subj":"T20","obj":"http://purl.obolibrary.org/obo/CHEBI_367163"},{"id":"A21","pred":"chebi_id","subj":"T21","obj":"http://purl.obolibrary.org/obo/CHEBI_145994"},{"subj":"T16","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T17","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T19","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T20","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T21","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T42","span":{"begin":75,"end":219},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T42","pred":"source","obj":"LitCovid-sentences"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PubTator","color":"#93ecab","default":true},{"id":"LitCovid-PD-MONDO","color":"#ec9394"},{"id":"LitCovid-PD-CLO","color":"#93aeec"},{"id":"LitCovid-PD-CHEBI","color":"#c8ec93"},{"id":"LitCovid-sentences","color":"#ec93e2"}]}]}}