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PMC:7195088 / 57711-58841 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
1721 18-26 Species denotes patients Tax:9606
1722 513-521 Species denotes patients Tax:9606
1723 582-590 Species denotes Patients Tax:9606
1724 557-570 Chemical denotes dexamethasone MESH:D003907
1725 617-630 Chemical denotes dexamethasone MESH:D003907
1726 818-831 Chemical denotes dexamethasone MESH:D003907
1727 1083-1096 Chemical denotes dexamethasone MESH:D003907
1728 3-17 Disease denotes critically ill MESH:D016638
1729 76-100 Disease denotes inflammation–coagulation MESH:D001778
1730 136-171 Disease denotes acute respiratory distress syndrome MESH:D012128
1731 173-177 Disease denotes ARDS MESH:D012128
1732 246-250 Disease denotes ARDS MESH:D012128
1733 342-354 Disease denotes inflammation MESH:D007249
1734 527-531 Disease denotes ARDS MESH:D012128
1735 943-952 Disease denotes mortality MESH:D003643

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T91 385-390 Body_part denotes organ http://purl.org/sig/ont/fma/fma67498
T92 604-607 Body_part denotes arm http://purl.org/sig/ont/fma/fma24890

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T46 385-390 Body_part denotes organ http://purl.obolibrary.org/obo/UBERON_0000062
T47 604-607 Body_part denotes arm http://purl.obolibrary.org/obo/UBERON_0001460

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T99 142-162 Phenotype denotes respiratory distress http://purl.obolibrary.org/obo/HP_0002098

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T328 76-88 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T329 136-171 Disease denotes acute respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0006502
T330 142-171 Disease denotes respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0009971
T331 173-177 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T332 246-250 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T333 342-354 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T334 527-531 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T318 205-206 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T319 295-296 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T320 385-390 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organ
T321 475-476 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T322 604-607 http://www.ebi.ac.uk/efo/EFO_0001410 denotes arm
T323 749-750 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T324 916-917 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T98872 28-43 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T54230 224-238 Chemical denotes corticosteroid http://purl.obolibrary.org/obo/CHEBI_50858
T17441 557-570 Chemical denotes dexamethasone http://purl.obolibrary.org/obo/CHEBI_41879
T90766 617-630 Chemical denotes dexamethasone http://purl.obolibrary.org/obo/CHEBI_41879
T70095 818-831 Chemical denotes dexamethasone http://purl.obolibrary.org/obo/CHEBI_41879
T42283 832-837 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T49874 858-863 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T47088 873-878 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T59830 973-978 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T57744 1083-1096 Chemical denotes dexamethasone http://purl.obolibrary.org/obo/CHEBI_41879
T54060 1097-1102 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T69982 1119-1124 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T25 76-88 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T26 89-100 http://purl.obolibrary.org/obo/GO_0050817 denotes coagulation
T27 342-354 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T425 0-204 Sentence denotes In critically ill patients, corticosteroids may be provided to decrease the inflammation–coagulation–fibroproliferation observed during acute respiratory distress syndrome (ARDS) [[58], [59], [60], [61]].
T426 205-474 Sentence denotes A meta-analysis on corticosteroid use in ARDS including eight controlled studies reported a significant reduction in markers of systemic inflammation, pulmonary and extrapulmonary organ dysfunction scores, duration of mechanical ventilation and ICU length of stay [62].
T427 475-581 Sentence denotes A recent multicentre RCT included 277 patients with ARDS to assess the effects of dexamethasone treatment.
T428 582-728 Sentence denotes Patients in the study arm received dexamethasone 20 mg once daily from day 1 to day 5, which was reduced to 10 mg once daily from day 6 to day 10.
T429 729-1008 Sentence denotes This study reported a significant reduction in duration of mechanical ventilation in the dexamethasone group than in the control group (between-group difference 4.8 days, p < 0.0001) and a significant reduction in mortality at 60 days (between-group difference −15.3%, p 0.0047).
T430 1009-1130 Sentence denotes The proportion of adverse events did not differ significantly between the dexamethasone group and the control group [63].

2_test

Id Subject Object Predicate Lexical cue
32360444-22088618-22369798 181-183 22088618 denotes 58
32360444-7587435-22369799 187-189 7587435 denotes 59
32360444-11934726-22369800 193-195 11934726 denotes 60
32360444-21983371-22369801 199-201 21983371 denotes 61
32360444-19325471-22369802 470-472 19325471 denotes 62
32360444-32043986-22369803 1126-1128 32043986 denotes 63