PMC:7195088 / 55052-56136
Annnotations
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 1633 | 95-103 | Species | denotes | patients | Tax:9606 |
| 1634 | 261-269 | Species | denotes | patients | Tax:9606 |
| 1635 | 589-597 | Species | denotes | patients | Tax:9606 |
| 1636 | 747-755 | Species | denotes | patients | Tax:9606 |
| 1637 | 80-94 | Disease | denotes | critically ill | MESH:D016638 |
| 1638 | 109-118 | Disease | denotes | pneumonia | MESH:D011014 |
| 1639 | 126-134 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 1640 | 143-162 | Disease | denotes | bacterial infection | MESH:D001424 |
| 1641 | 236-247 | Disease | denotes | coinfection | MESH:D060085 |
| 1642 | 275-290 | Disease | denotes | viral pneumonia | |
| 1643 | 411-420 | Disease | denotes | mortality | MESH:D003643 |
| 1644 | 580-588 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 1645 | 738-746 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 1646 | 818-827 | Disease | denotes | pneumonia | MESH:D011014 |
| 1647 | 847-856 | Disease | denotes | pneumonia | MESH:D011014 |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T92 | 109-118 | Phenotype | denotes | pneumonia | http://purl.obolibrary.org/obo/HP_0002090 |
| T93 | 281-290 | Phenotype | denotes | pneumonia | http://purl.obolibrary.org/obo/HP_0002090 |
| T94 | 818-827 | Phenotype | denotes | pneumonia | http://purl.obolibrary.org/obo/HP_0002090 |
| T95 | 847-856 | Phenotype | denotes | pneumonia | http://purl.obolibrary.org/obo/HP_0002090 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T303 | 109-118 | Disease | denotes | pneumonia | http://purl.obolibrary.org/obo/MONDO_0005249 |
| T304 | 126-134 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T305 | 143-162 | Disease | denotes | bacterial infection | http://purl.obolibrary.org/obo/MONDO_0005113 |
| T306 | 153-162 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T307 | 275-290 | Disease | denotes | viral pneumonia | http://purl.obolibrary.org/obo/MONDO_0006012 |
| T308 | 281-290 | Disease | denotes | pneumonia | http://purl.obolibrary.org/obo/MONDO_0005249 |
| T309 | 580-588 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T310 | 738-746 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T311 | 818-827 | Disease | denotes | pneumonia | http://purl.obolibrary.org/obo/MONDO_0005249 |
| T312 | 847-856 | Disease | denotes | pneumonia | http://purl.obolibrary.org/obo/MONDO_0005249 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T312 | 326-327 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T998 | 56-66 | Chemical | denotes | antibiotic | http://purl.obolibrary.org/obo/CHEBI_33281 |
| T84200 | 522-535 | Chemical | denotes | antimicrobial | http://purl.obolibrary.org/obo/CHEBI_33281 |
| T38237 | 877-896 | Chemical | denotes | antimicrobial agent | http://purl.obolibrary.org/obo/CHEBI_33281 |
| T27580 | 950-960 | Chemical | denotes | antibiotic | http://purl.obolibrary.org/obo/CHEBI_33281 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T414 | 0-182 | Sentence | denotes | In our opinion, it might be prudent to consider empiric antibiotic treatment in critically ill patients with pneumonia due to COVID-19 in whom bacterial infection cannot be excluded. |
| T415 | 183-421 | Sentence | denotes | This suggestion is based on the facts that bacterial coinfection is common in patients with viral pneumonia and that it can be associated with a substantial risk of delaying appropriate treatment, thereby potentially increasing mortality. |
| T416 | 422-669 | Sentence | denotes | Because of the limited available data on both the microbiologic epidemiology (and the prevalence of antimicrobial resistance) of bacterial superinfections in COVID-19 patients, it is difficult to provide specific pathogen-oriented recommendations. |
| T417 | 670-1084 | Sentence | denotes | Therefore, pending further studies, we suggest to empirically treat COVID-19 patients according to their clinical syndrome (e.g. community-acquired pneumonia, hospital-acquired pneumonia), choosing the best antimicrobial agent or agents on the basis of local guidelines and local antibiotic susceptibility patterns, with early de-escalation or discontinuation according to microbiology results, whenever available. |