PMC:7190487 / 1355-1928 JSON TXT

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Id	Subject	Object	Predicate	Lexical cue	fma_id
T8	193-197	Body_part	denotes	lung	http://purl.org/sig/ont/fma/fma7195
T9	480-494	Body_part	denotes	umbilical vein	http://purl.org/sig/ont/fma/fma70317
T10	495-512	Body_part	denotes	endothelial cells	http://purl.org/sig/ont/fma/fma66772
T11	507-512	Body_part	denotes	cells	http://purl.org/sig/ont/fma/fma68646
T12	542-548	Body_part	denotes	kidney	http://purl.org/sig/ont/fma/fma7203
T13	563-568	Body_part	denotes	cells	http://purl.org/sig/ont/fma/fma68646

Id	Subject	Object	Predicate	Lexical cue	uberon_id
T1	193-197	Body_part	denotes	lung	http://purl.obolibrary.org/obo/UBERON_0002048
T2	480-494	Body_part	denotes	umbilical vein	http://purl.obolibrary.org/obo/UBERON_0002066
T3	490-494	Body_part	denotes	vein	http://purl.obolibrary.org/obo/UBERON_0001638
T4	542-548	Body_part	denotes	kidney	http://purl.obolibrary.org/obo/UBERON_0002113

Id	Subject	Object	Predicate	Lexical cue	mondo_id
T7	0-35	Disease	denotes	Acute Respiratory Distress Syndrome	http://purl.obolibrary.org/obo/MONDO_0006502
T8	6-35	Disease	denotes	Respiratory Distress Syndrome	http://purl.obolibrary.org/obo/MONDO_0009971
T9	37-41	Disease	denotes	ARDS	http://purl.obolibrary.org/obo/MONDO_0006502
T10	109-117	Disease	denotes	COVID-19	http://purl.obolibrary.org/obo/MONDO_0100096
T11	187-204	Disease	denotes	acute lung injury	http://purl.obolibrary.org/obo/MONDO_0006502\|http://purl.obolibrary.org/obo/MONDO_0015796
T13	198-204	Disease	denotes	injury	http://purl.obolibrary.org/obo/MONDO_0021178
T14	206-209	Disease	denotes	ALI	http://purl.obolibrary.org/obo/MONDO_0006502
T15	225-233	Disease	denotes	SARS-CoV	http://purl.obolibrary.org/obo/MONDO_0005091
T16	281-284	Disease	denotes	ALI	http://purl.obolibrary.org/obo/MONDO_0006502

Id	Subject	Object	Predicate	Lexical cue
T12	139-145	http://purl.obolibrary.org/obo/NCBITaxon_33208	denotes	animal
T13	193-197	http://purl.obolibrary.org/obo/UBERON_0002048	denotes	lung
T14	193-197	http://www.ebi.ac.uk/efo/EFO_0000934	denotes	lung
T15	242-245	http://purl.obolibrary.org/obo/CLO_0051582	denotes	has
T16	353-356	http://purl.obolibrary.org/obo/CLO_0051582	denotes	has
T17	474-479	http://purl.obolibrary.org/obo/NCBITaxon_9606	denotes	human
T18	480-494	http://purl.obolibrary.org/obo/UBERON_0002066	denotes	umbilical vein
T19	480-494	http://www.ebi.ac.uk/efo/EFO_0001940	denotes	umbilical vein
T20	495-512	http://purl.obolibrary.org/obo/CL_0000115	denotes	endothelial cells
T21	514-520	http://purl.obolibrary.org/obo/CLO_0004307	denotes	HUVECs
T22	526-531	http://purl.obolibrary.org/obo/NCBITaxon_9606	denotes	human
T23	532-548	http://www.ebi.ac.uk/efo/EFO_0000927	denotes	embryonic kidney
T24	549-552	http://purl.obolibrary.org/obo/CLO_0001230	denotes	293
T25	549-552	http://purl.obolibrary.org/obo/CLO_0037237	denotes	293
T26	549-552	http://purl.obolibrary.org/obo/CLO_0050903	denotes	293
T27	549-552	http://purl.obolibrary.org/obo/CLO_0054249	denotes	293
T28	549-552	http://purl.obolibrary.org/obo/CLO_0054250	denotes	293
T29	549-552	http://purl.obolibrary.org/obo/CLO_0054251	denotes	293
T30	549-552	http://purl.obolibrary.org/obo/CLO_0054252	denotes	293
T31	563-568	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells

Id	Subject	Object	Predicate	Lexical cue
T10	303-312	http://purl.obolibrary.org/obo/GO_0016236	denotes	autophagy
T11	303-312	http://purl.obolibrary.org/obo/GO_0006914	denotes	autophagy
T12	325-329	http://purl.obolibrary.org/obo/GO_0050405	denotes	AMPK
T13	325-329	http://purl.obolibrary.org/obo/GO_0047322	denotes	AMPK
T14	325-329	http://purl.obolibrary.org/obo/GO_0004691	denotes	AMPK
T15	348-352	http://purl.obolibrary.org/obo/GO_0050405	denotes	AMPK
T16	348-352	http://purl.obolibrary.org/obo/GO_0047322	denotes	AMPK
T17	348-352	http://purl.obolibrary.org/obo/GO_0004691	denotes	AMPK
T18	443-458	http://purl.obolibrary.org/obo/GO_0016310	denotes	phosphorylating

Id	Subject	Object	Predicate	Lexical cue
T16	0-122	Sentence	denotes	Acute Respiratory Distress Syndrome (ARDS) is one of the commonest complications developing in patients with COVID-19 [6].
T17	123-238	Sentence	denotes	There have been animal studies that have implicated ACE2 in the acute lung injury (ALI) caused due to SARS-CoV [4].
T18	239-347	Sentence	denotes	It has been hypothesized that ACE2 causes ALI by bringing about autophagy through the AMPK/mTOR pathway [7].
T19	348-573	Sentence	denotes	AMPK has been shown to increase the expression of ACE2 as well as to increase its stability by phosphorylating ACE2 Ser680 in human umbilical vein endothelial cells (HUVECs) and human embryonic kidney 293 (HEK293T) cells [8].

Id	Subject	Object	Predicate	Lexical cue	hp_id
T1	6-26	Phenotype	denotes	Respiratory Distress	http://purl.obolibrary.org/obo/HP_0002098
T2	187-204	Phenotype	denotes	acute lung injury	http://www.orpha.net/ORDO/Orphanet_178320
T3	206-209	Phenotype	denotes	ALI	http://www.orpha.net/ORDO/Orphanet_178320
T4	281-284	Phenotype	denotes	ALI	http://www.orpha.net/ORDO/Orphanet_178320

Id	Subject	Object	Predicate	Lexical cue
32360697-31986264-25244885	119-120	31986264	denotes	6
32360697-31356776-25244886	344-345	31356776	denotes	7

Id	Subject	Object	Predicate	Lexical cue	tao:has_database_id
78	175-179	Gene	denotes	ACE2	Gene:59272
79	269-273	Gene	denotes	ACE2	Gene:59272
80	325-329	Gene	denotes	AMPK	Gene:5563
81	330-334	Gene	denotes	mTOR	Gene:2475
82	348-352	Gene	denotes	AMPK	Gene:5563
83	398-402	Gene	denotes	ACE2	Gene:59272
84	459-463	Gene	denotes	ACE2	Gene:59272
85	95-103	Species	denotes	patients	Tax:9606
86	225-233	Species	denotes	SARS-CoV	Tax:694009
87	474-479	Species	denotes	human	Tax:9606
88	526-531	Species	denotes	human	Tax:9606
89	464-470	Chemical	denotes	Ser680
90	0-35	Disease	denotes	Acute Respiratory Distress Syndrome	MESH:D012128
91	37-41	Disease	denotes	ARDS	MESH:D012128
92	109-117	Disease	denotes	COVID-19	MESH:C000657245
93	187-204	Disease	denotes	acute lung injury	MESH:D055371
94	532-548	Disease	denotes	embryonic kidney	MESH:D007674
95	549-562	CellLine	denotes	293 (HEK293T)	CVCL:0063