PMC:7189872 / 23005-23543 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"432","span":{"begin":350,"end":356},"obj":"Gene"},{"id":"433","span":{"begin":114,"end":119},"obj":"Gene"},{"id":"434","span":{"begin":361,"end":367},"obj":"Gene"},{"id":"435","span":{"begin":167,"end":175},"obj":"Species"},{"id":"436","span":{"begin":216,"end":226},"obj":"Species"},{"id":"437","span":{"begin":380,"end":390},"obj":"Species"},{"id":"440","span":{"begin":50,"end":58},"obj":"Disease"}],"attributes":[{"id":"A432","pred":"tao:has_database_id","subj":"432","obj":"Gene:43740569"},{"id":"A433","pred":"tao:has_database_id","subj":"433","obj":"Gene:43740568"},{"id":"A434","pred":"tao:has_database_id","subj":"434","obj":"Gene:43740573"},{"id":"A435","pred":"tao:has_database_id","subj":"435","obj":"Tax:694009"},{"id":"A436","pred":"tao:has_database_id","subj":"436","obj":"Tax:2697049"},{"id":"A437","pred":"tao:has_database_id","subj":"437","obj":"Tax:2697049"},{"id":"A440","pred":"tao:has_database_id","subj":"440","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"In a similar study of the preliminary analysis of COVID-19 vaccine targets [1] the investigators tried to use the spike protein and nucleo-capsid protein sequences of SARS-COV that are homologous to some extant with SARS-COV-2 proteins to determine multiple different epitopes for Vaccine prediction, but in our study out of five two proteins namely ORF-3a and ORF-7a specific to SARS-COV-2 were found to be putative T-cell epitope determinants that create useful information; these proteins are also important for viral replication [41]."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T214","span":{"begin":120,"end":127},"obj":"Body_part"},{"id":"T215","span":{"begin":146,"end":153},"obj":"Body_part"},{"id":"T216","span":{"begin":227,"end":235},"obj":"Body_part"},{"id":"T217","span":{"begin":334,"end":342},"obj":"Body_part"},{"id":"T218","span":{"begin":419,"end":423},"obj":"Body_part"},{"id":"T219","span":{"begin":483,"end":491},"obj":"Body_part"}],"attributes":[{"id":"A214","pred":"fma_id","subj":"T214","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A215","pred":"fma_id","subj":"T215","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A216","pred":"fma_id","subj":"T216","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A217","pred":"fma_id","subj":"T217","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A218","pred":"fma_id","subj":"T218","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A219","pred":"fma_id","subj":"T219","obj":"http://purl.org/sig/ont/fma/fma67257"}],"text":"In a similar study of the preliminary analysis of COVID-19 vaccine targets [1] the investigators tried to use the spike protein and nucleo-capsid protein sequences of SARS-COV that are homologous to some extant with SARS-COV-2 proteins to determine multiple different epitopes for Vaccine prediction, but in our study out of five two proteins namely ORF-3a and ORF-7a specific to SARS-COV-2 were found to be putative T-cell epitope determinants that create useful information; these proteins are also important for viral replication [41]."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T36","span":{"begin":50,"end":58},"obj":"Disease"},{"id":"T37","span":{"begin":167,"end":171},"obj":"Disease"},{"id":"T38","span":{"begin":216,"end":220},"obj":"Disease"},{"id":"T39","span":{"begin":380,"end":384},"obj":"Disease"}],"attributes":[{"id":"A36","pred":"mondo_id","subj":"T36","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A37","pred":"mondo_id","subj":"T37","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A38","pred":"mondo_id","subj":"T38","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A39","pred":"mondo_id","subj":"T39","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"In a similar study of the preliminary analysis of COVID-19 vaccine targets [1] the investigators tried to use the spike protein and nucleo-capsid protein sequences of SARS-COV that are homologous to some extant with SARS-COV-2 proteins to determine multiple different epitopes for Vaccine prediction, but in our study out of five two proteins namely ORF-3a and ORF-7a specific to SARS-COV-2 were found to be putative T-cell epitope determinants that create useful information; these proteins are also important for viral replication [41]."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T178","span":{"begin":3,"end":4},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T179","span":{"begin":417,"end":423},"obj":"http://purl.obolibrary.org/obo/CL_0000084"},{"id":"T180","span":{"begin":534,"end":536},"obj":"http://purl.obolibrary.org/obo/CLO_0053794"}],"text":"In a similar study of the preliminary analysis of COVID-19 vaccine targets [1] the investigators tried to use the spike protein and nucleo-capsid protein sequences of SARS-COV that are homologous to some extant with SARS-COV-2 proteins to determine multiple different epitopes for Vaccine prediction, but in our study out of five two proteins namely ORF-3a and ORF-7a specific to SARS-COV-2 were found to be putative T-cell epitope determinants that create useful information; these proteins are also important for viral replication [41]."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T178","span":{"begin":120,"end":127},"obj":"Chemical"},{"id":"T179","span":{"begin":132,"end":138},"obj":"Chemical"},{"id":"T180","span":{"begin":146,"end":153},"obj":"Chemical"},{"id":"T181","span":{"begin":227,"end":235},"obj":"Chemical"},{"id":"T182","span":{"begin":334,"end":342},"obj":"Chemical"},{"id":"T183","span":{"begin":424,"end":431},"obj":"Chemical"},{"id":"T184","span":{"begin":483,"end":491},"obj":"Chemical"}],"attributes":[{"id":"A178","pred":"chebi_id","subj":"T178","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A179","pred":"chebi_id","subj":"T179","obj":"http://purl.obolibrary.org/obo/CHEBI_33252"},{"id":"A180","pred":"chebi_id","subj":"T180","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A181","pred":"chebi_id","subj":"T181","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A182","pred":"chebi_id","subj":"T182","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A183","pred":"chebi_id","subj":"T183","obj":"http://purl.obolibrary.org/obo/CHEBI_53000"},{"id":"A184","pred":"chebi_id","subj":"T184","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"}],"text":"In a similar study of the preliminary analysis of COVID-19 vaccine targets [1] the investigators tried to use the spike protein and nucleo-capsid protein sequences of SARS-COV that are homologous to some extant with SARS-COV-2 proteins to determine multiple different epitopes for Vaccine prediction, but in our study out of five two proteins namely ORF-3a and ORF-7a specific to SARS-COV-2 were found to be putative T-cell epitope determinants that create useful information; these proteins are also important for viral replication [41]."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T21","span":{"begin":515,"end":532},"obj":"http://purl.obolibrary.org/obo/GO_0019079"},{"id":"T22","span":{"begin":515,"end":532},"obj":"http://purl.obolibrary.org/obo/GO_0019058"}],"text":"In a similar study of the preliminary analysis of COVID-19 vaccine targets [1] the investigators tried to use the spike protein and nucleo-capsid protein sequences of SARS-COV that are homologous to some extant with SARS-COV-2 proteins to determine multiple different epitopes for Vaccine prediction, but in our study out of five two proteins namely ORF-3a and ORF-7a specific to SARS-COV-2 were found to be putative T-cell epitope determinants that create useful information; these proteins are also important for viral replication [41]."}

{"project":"LitCovid-sentences","denotations":[{"id":"T197","span":{"begin":0,"end":538},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"In a similar study of the preliminary analysis of COVID-19 vaccine targets [1] the investigators tried to use the spike protein and nucleo-capsid protein sequences of SARS-COV that are homologous to some extant with SARS-COV-2 proteins to determine multiple different epitopes for Vaccine prediction, but in our study out of five two proteins namely ORF-3a and ORF-7a specific to SARS-COV-2 were found to be putative T-cell epitope determinants that create useful information; these proteins are also important for viral replication [41]."}

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T445","span":{"begin":50,"end":58},"obj":"SP_7"},{"id":"T446","span":{"begin":167,"end":175},"obj":"SP_10"},{"id":"T447","span":{"begin":185,"end":195},"obj":"SO:0000853"},{"id":"T448","span":{"begin":216,"end":226},"obj":"SP_7"},{"id":"T449","span":{"begin":268,"end":276},"obj":"BV_9"},{"id":"T450","span":{"begin":350,"end":353},"obj":"SO:0000236"},{"id":"T451","span":{"begin":361,"end":364},"obj":"SO:0000236"},{"id":"T452","span":{"begin":380,"end":390},"obj":"SP_7"},{"id":"T453","span":{"begin":417,"end":423},"obj":"CL:0000084"},{"id":"T454","span":{"begin":424,"end":431},"obj":"BV_9"},{"id":"T455","span":{"begin":515,"end":520},"obj":"NCBITaxon:10239;GO:0006260"},{"id":"T456","span":{"begin":521,"end":532},"obj":"GO:0006260"},{"id":"T44148","span":{"begin":50,"end":58},"obj":"SP_7"},{"id":"T48419","span":{"begin":167,"end":175},"obj":"SP_10"},{"id":"T15410","span":{"begin":185,"end":195},"obj":"SO:0000853"},{"id":"T45966","span":{"begin":216,"end":226},"obj":"SP_7"},{"id":"T91878","span":{"begin":268,"end":276},"obj":"BV_9"},{"id":"T64466","span":{"begin":350,"end":353},"obj":"SO:0000236"},{"id":"T31987","span":{"begin":361,"end":364},"obj":"SO:0000236"},{"id":"T22365","span":{"begin":380,"end":390},"obj":"SP_7"},{"id":"T96116","span":{"begin":417,"end":423},"obj":"CL:0000084"},{"id":"T26337","span":{"begin":424,"end":431},"obj":"BV_9"},{"id":"T95242","span":{"begin":515,"end":520},"obj":"NCBITaxon:10239;GO:0006260"},{"id":"T76165","span":{"begin":521,"end":532},"obj":"GO:0006260"}],"text":"In a similar study of the preliminary analysis of COVID-19 vaccine targets [1] the investigators tried to use the spike protein and nucleo-capsid protein sequences of SARS-COV that are homologous to some extant with SARS-COV-2 proteins to determine multiple different epitopes for Vaccine prediction, but in our study out of five two proteins namely ORF-3a and ORF-7a specific to SARS-COV-2 were found to be putative T-cell epitope determinants that create useful information; these proteins are also important for viral replication [41]."}

{"project":"2_test","denotations":[{"id":"32352026-30822457-47638080","span":{"begin":534,"end":536},"obj":"30822457"},{"id":"T54895","span":{"begin":534,"end":536},"obj":"30822457"}],"text":"In a similar study of the preliminary analysis of COVID-19 vaccine targets [1] the investigators tried to use the spike protein and nucleo-capsid protein sequences of SARS-COV that are homologous to some extant with SARS-COV-2 proteins to determine multiple different epitopes for Vaccine prediction, but in our study out of five two proteins namely ORF-3a and ORF-7a specific to SARS-COV-2 were found to be putative T-cell epitope determinants that create useful information; these proteins are also important for viral replication [41]."}