PMC:7189872 / 18764-19441 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"347","span":{"begin":515,"end":524},"obj":"Species"},{"id":"350","span":{"begin":360,"end":369},"obj":"Species"},{"id":"351","span":{"begin":240,"end":254},"obj":"Disease"}],"attributes":[{"id":"A347","pred":"tao:has_database_id","subj":"347","obj":"Tax:9606"},{"id":"A350","pred":"tao:has_database_id","subj":"350","obj":"Tax:9606"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"In Table 8 , ProtParam analysis further reveals the stability of the considered epitopes and final revelation of one epitope ITLCFTLKR is screened out. This particular Epitope exhibits an instability index of 35.68, with a grand average of hydropathicity (GRAVY) calculated was 0.844, and the estimated half-life for this peptide was determined to be 20 h for mammalian reticulocytes.\nTable 8 ProtParam analysis for selected epitopes.\nSelected Epitope GRAVY Score Instability Index (Indication) Estimated Half-Life(Mammalian reticulocytes) Theoretical pI Aliphatic Index\nITLCFTLKR 0.844 35.68(Stable) 20 Hours 9.51 130.00\nVYQLRARSV −0.067 70.73(Unstable) 100 Hours 10.83 118.89"}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T185","span":{"begin":370,"end":383},"obj":"Body_part"},{"id":"T186","span":{"begin":525,"end":538},"obj":"Body_part"}],"attributes":[{"id":"A185","pred":"fma_id","subj":"T185","obj":"http://purl.org/sig/ont/fma/fma66785"},{"id":"A186","pred":"fma_id","subj":"T186","obj":"http://purl.org/sig/ont/fma/fma66785"}],"text":"In Table 8 , ProtParam analysis further reveals the stability of the considered epitopes and final revelation of one epitope ITLCFTLKR is screened out. This particular Epitope exhibits an instability index of 35.68, with a grand average of hydropathicity (GRAVY) calculated was 0.844, and the estimated half-life for this peptide was determined to be 20 h for mammalian reticulocytes.\nTable 8 ProtParam analysis for selected epitopes.\nSelected Epitope GRAVY Score Instability Index (Indication) Estimated Half-Life(Mammalian reticulocytes) Theoretical pI Aliphatic Index\nITLCFTLKR 0.844 35.68(Stable) 20 Hours 9.51 130.00\nVYQLRARSV −0.067 70.73(Unstable) 100 Hours 10.83 118.89"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T148","span":{"begin":221,"end":222},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T149","span":{"begin":322,"end":329},"obj":"http://purl.obolibrary.org/obo/PR_000018263"}],"text":"In Table 8 , ProtParam analysis further reveals the stability of the considered epitopes and final revelation of one epitope ITLCFTLKR is screened out. This particular Epitope exhibits an instability index of 35.68, with a grand average of hydropathicity (GRAVY) calculated was 0.844, and the estimated half-life for this peptide was determined to be 20 h for mammalian reticulocytes.\nTable 8 ProtParam analysis for selected epitopes.\nSelected Epitope GRAVY Score Instability Index (Indication) Estimated Half-Life(Mammalian reticulocytes) Theoretical pI Aliphatic Index\nITLCFTLKR 0.844 35.68(Stable) 20 Hours 9.51 130.00\nVYQLRARSV −0.067 70.73(Unstable) 100 Hours 10.83 118.89"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T159","span":{"begin":117,"end":124},"obj":"Chemical"},{"id":"T160","span":{"begin":322,"end":329},"obj":"Chemical"}],"attributes":[{"id":"A159","pred":"chebi_id","subj":"T159","obj":"http://purl.obolibrary.org/obo/CHEBI_53000"},{"id":"A160","pred":"chebi_id","subj":"T160","obj":"http://purl.obolibrary.org/obo/CHEBI_16670"}],"text":"In Table 8 , ProtParam analysis further reveals the stability of the considered epitopes and final revelation of one epitope ITLCFTLKR is screened out. This particular Epitope exhibits an instability index of 35.68, with a grand average of hydropathicity (GRAVY) calculated was 0.844, and the estimated half-life for this peptide was determined to be 20 h for mammalian reticulocytes.\nTable 8 ProtParam analysis for selected epitopes.\nSelected Epitope GRAVY Score Instability Index (Indication) Estimated Half-Life(Mammalian reticulocytes) Theoretical pI Aliphatic Index\nITLCFTLKR 0.844 35.68(Stable) 20 Hours 9.51 130.00\nVYQLRARSV −0.067 70.73(Unstable) 100 Hours 10.83 118.89"}

{"project":"LitCovid-sentences","denotations":[{"id":"T173","span":{"begin":0,"end":151},"obj":"Sentence"},{"id":"T174","span":{"begin":152,"end":384},"obj":"Sentence"},{"id":"T175","span":{"begin":385,"end":434},"obj":"Sentence"},{"id":"T176","span":{"begin":435,"end":570},"obj":"Sentence"},{"id":"T177","span":{"begin":571,"end":621},"obj":"Sentence"},{"id":"T178","span":{"begin":622,"end":677},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"In Table 8 , ProtParam analysis further reveals the stability of the considered epitopes and final revelation of one epitope ITLCFTLKR is screened out. This particular Epitope exhibits an instability index of 35.68, with a grand average of hydropathicity (GRAVY) calculated was 0.844, and the estimated half-life for this peptide was determined to be 20 h for mammalian reticulocytes.\nTable 8 ProtParam analysis for selected epitopes.\nSelected Epitope GRAVY Score Instability Index (Indication) Estimated Half-Life(Mammalian reticulocytes) Theoretical pI Aliphatic Index\nITLCFTLKR 0.844 35.68(Stable) 20 Hours 9.51 130.00\nVYQLRARSV −0.067 70.73(Unstable) 100 Hours 10.83 118.89"}

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T369","span":{"begin":80,"end":88},"obj":"BV_9"},{"id":"T370","span":{"begin":117,"end":124},"obj":"BV_9"},{"id":"T371","span":{"begin":168,"end":175},"obj":"BV_9"},{"id":"T372","span":{"begin":360,"end":369},"obj":"NCBITaxon:40674"},{"id":"T373","span":{"begin":370,"end":383},"obj":"CL:0000558"},{"id":"T377","span":{"begin":425,"end":433},"obj":"BV_9"}],"text":"In Table 8 , ProtParam analysis further reveals the stability of the considered epitopes and final revelation of one epitope ITLCFTLKR is screened out. This particular Epitope exhibits an instability index of 35.68, with a grand average of hydropathicity (GRAVY) calculated was 0.844, and the estimated half-life for this peptide was determined to be 20 h for mammalian reticulocytes.\nTable 8 ProtParam analysis for selected epitopes.\nSelected Epitope GRAVY Score Instability Index (Indication) Estimated Half-Life(Mammalian reticulocytes) Theoretical pI Aliphatic Index\nITLCFTLKR 0.844 35.68(Stable) 20 Hours 9.51 130.00\nVYQLRARSV −0.067 70.73(Unstable) 100 Hours 10.83 118.89"}