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PMC:7172841 / 24265-24942 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T152 207-216 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T153 294-298 Body_part denotes IL-1 http://purl.org/sig/ont/fma/fma86583
T154 329-333 Body_part denotes IL-1 http://purl.org/sig/ont/fma/fma86583
T155 429-438 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T156 442-451 Body_part denotes monocytes http://purl.org/sig/ont/fma/fma62864
T157 473-484 Body_part denotes lymphocytes http://purl.org/sig/ont/fma/fma62863
T158 537-541 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T159 596-605 Body_part denotes (NK) cell http://purl.org/sig/ont/fma/fma63147
T160 601-605 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T218 18-27 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T219 38-46 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T220 38-42 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T221 150-153 Disease denotes MAS http://purl.obolibrary.org/obo/MONDO_0015545
T222 305-308 Disease denotes MAS http://purl.obolibrary.org/obo/MONDO_0015545
T223 506-517 Disease denotes lymphopenia http://purl.obolibrary.org/obo/MONDO_0003783
T224 542-553 Disease denotes lymphopenia http://purl.obolibrary.org/obo/MONDO_0003783

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T219 442-451 http://purl.obolibrary.org/obo/CL_0000576 denotes monocytes
T220 502-505 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T221 535-541 http://purl.obolibrary.org/obo/CL_0000236 denotes B cell
T222 596-605 http://purl.obolibrary.org/obo/CL_0000623 denotes (NK) cell
T223 671-676 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T144 278-280 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T146 294-296 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T148 329-331 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T29 79-101 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammatory responses

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T180 0-335 Sentence denotes All patients with pneumonia caused by SARS-CoV-2 who develop SRF display hyper-inflammatory responses with features of either immune dysregulation or MAS, both of which are characterized by pro-inflammatory cytokines: the immune dysregulation described here, which is driven by IL-6 and not by IL-1β, and MAS, which is driven by IL-1β.
T181 336-554 Sentence denotes There are two key features of this immune dysregulation: over-production of pro-inflammatory cytokines by monocytes and dysregulation of lymphocytes characterized by CD4 lymphopenia and subsequently B cell lymphopenia.
T182 555-677 Sentence denotes In parallel, the absolute natural killer (NK) cell count is depleted, probably as result of the rapidly propagating virus.

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T86 18-27 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T87 126-146 Phenotype denotes immune dysregulation http://purl.obolibrary.org/obo/HP_0002958
T88 222-242 Phenotype denotes immune dysregulation http://purl.obolibrary.org/obo/HP_0002958
T89 371-391 Phenotype denotes immune dysregulation http://purl.obolibrary.org/obo/HP_0002958
T90 506-517 Phenotype denotes lymphopenia http://purl.obolibrary.org/obo/HP_0001888
T91 535-553 Phenotype denotes B cell lymphopenia http://purl.obolibrary.org/obo/HP_0010976

LitCovid-PMC-OGER-BB

Id Subject Object Predicate Lexical cue
T774 38-48 SP_7 denotes SARS-CoV-2
T775 126-132 UBERON:0002405 denotes immune
T776 133-146 GO:0065007 denotes dysregulation
T777 222-228 UBERON:0002405;GO:0006955 denotes immune
T778 229-242 GO:0065007 denotes dysregulation
T779 278-282 PR:000001393 denotes IL-6
T780 294-299 PR:000001136 denotes IL-1β
T781 329-334 PR:000001136 denotes IL-1β
T782 371-377 UBERON:0002405 denotes immune
T783 378-391 GO:0065007 denotes dysregulation
T784 442-451 CL:0000576 denotes monocytes
T785 456-469 GO:0065007 denotes dysregulation
T786 473-484 CL:0000542 denotes lymphocytes
T787 502-505 PR:000001004 denotes CD4
T788 535-541 CL:0000236 denotes B cell
T789 581-595 CL:0000623 denotes natural killer
T790 597-599 CL:0000623 denotes NK
T791 671-676 NCBITaxon:10239 denotes virus
T10521 135-145 SP_7 denotes sregulatio
T75385 223-229 UBERON:0002405 denotes mmune
T74786 230-243 GO:0065007 denotes ysregulation
T82585 319-324 UBERON:0002405;GO:0006955 denotes drive
T80560 325-338 GO:0065007 denotes by IL-1β. Th
T1347 375-379 PR:000001393 denotes ne d
T32757 391-396 PR:000001136 denotes : ove
T18461 426-431 PR:000001136 denotes ry cy
T99196 468-473 UBERON:0002405 denotes n of
T99785 474-487 GO:0065007 denotes ymphocytes ch
T92525 538-547 CL:0000576 denotes ell lymph
T72870 552-565 GO:0065007 denotes a. In paralle
T1208 569-580 CL:0000542 denotes he absolute
T5277 598-601 PR:000001004 denotes K)
T61893 631-637 CL:0000236 denotes ly as

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
978 278-282 Gene denotes IL-6 Gene:3569
979 294-299 Gene denotes IL-1β Gene:3552
980 329-334 Gene denotes IL-1β Gene:3552
981 502-505 Gene denotes CD4 Gene:920
982 4-12 Species denotes patients Tax:9606
983 38-48 Species denotes SARS-CoV-2 Tax:2697049
984 18-27 Disease denotes pneumonia MESH:D011014
985 61-91 Disease denotes SRF display hyper-inflammatory MESH:D007249
986 506-517 Disease denotes lymphopenia MESH:D008231
987 542-553 Disease denotes lymphopenia MESH:D008231