PMC:7172841 / 24265-24600 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7172841","sourcedb":"PMC","sourceid":"7172841","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7172841","text":"All patients with pneumonia caused by SARS-CoV-2 who develop SRF display hyper-inflammatory responses with features of either immune dysregulation or MAS, both of which are characterized by pro-inflammatory cytokines: the immune dysregulation described here, which is driven by IL-6 and not by IL-1β, and MAS, which is driven by IL-1β.","tracks":[{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T152","span":{"begin":207,"end":216},"obj":"Body_part"},{"id":"T153","span":{"begin":294,"end":298},"obj":"Body_part"},{"id":"T154","span":{"begin":329,"end":333},"obj":"Body_part"}],"attributes":[{"id":"A152","pred":"fma_id","subj":"T152","obj":"http://purl.org/sig/ont/fma/fma84050"},{"id":"A153","pred":"fma_id","subj":"T153","obj":"http://purl.org/sig/ont/fma/fma86583"},{"id":"A154","pred":"fma_id","subj":"T154","obj":"http://purl.org/sig/ont/fma/fma86583"},{"subj":"T152","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T153","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T154","pred":"source","obj":"LitCovid-PD-FMA-UBERON"}]},{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T218","span":{"begin":18,"end":27},"obj":"Disease"},{"id":"T219","span":{"begin":38,"end":46},"obj":"Disease"},{"id":"T220","span":{"begin":38,"end":42},"obj":"Disease"},{"id":"T221","span":{"begin":150,"end":153},"obj":"Disease"},{"id":"T222","span":{"begin":305,"end":308},"obj":"Disease"}],"attributes":[{"id":"A218","pred":"mondo_id","subj":"T218","obj":"http://purl.obolibrary.org/obo/MONDO_0005249"},{"id":"A219","pred":"mondo_id","subj":"T219","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A220","pred":"mondo_id","subj":"T220","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A221","pred":"mondo_id","subj":"T221","obj":"http://purl.obolibrary.org/obo/MONDO_0015545"},{"id":"A222","pred":"mondo_id","subj":"T222","obj":"http://purl.obolibrary.org/obo/MONDO_0015545"},{"subj":"T218","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T219","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T220","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T221","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T222","pred":"source","obj":"LitCovid-PD-MONDO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T144","span":{"begin":278,"end":280},"obj":"Chemical"},{"id":"T146","span":{"begin":294,"end":296},"obj":"Chemical"},{"id":"T148","span":{"begin":329,"end":331},"obj":"Chemical"}],"attributes":[{"id":"A144","pred":"chebi_id","subj":"T144","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A145","pred":"chebi_id","subj":"T144","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"},{"id":"A146","pred":"chebi_id","subj":"T146","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A147","pred":"chebi_id","subj":"T146","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"},{"id":"A148","pred":"chebi_id","subj":"T148","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A149","pred":"chebi_id","subj":"T148","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"},{"subj":"T144","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T146","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T148","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T29","span":{"begin":79,"end":101},"obj":"http://purl.obolibrary.org/obo/GO_0006954"}],"attributes":[{"subj":"T29","pred":"source","obj":"LitCovid-PD-GO-BP"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T180","span":{"begin":0,"end":335},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T180","pred":"source","obj":"LitCovid-sentences"}]},{"project":"LitCovid-PD-HP","denotations":[{"id":"T86","span":{"begin":18,"end":27},"obj":"Phenotype"},{"id":"T87","span":{"begin":126,"end":146},"obj":"Phenotype"},{"id":"T88","span":{"begin":222,"end":242},"obj":"Phenotype"}],"attributes":[{"id":"A86","pred":"hp_id","subj":"T86","obj":"http://purl.obolibrary.org/obo/HP_0002090"},{"id":"A87","pred":"hp_id","subj":"T87","obj":"http://purl.obolibrary.org/obo/HP_0002958"},{"id":"A88","pred":"hp_id","subj":"T88","obj":"http://purl.obolibrary.org/obo/HP_0002958"},{"subj":"T86","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T87","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T88","pred":"source","obj":"LitCovid-PD-HP"}]},{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T774","span":{"begin":38,"end":48},"obj":"SP_7"},{"id":"T775","span":{"begin":126,"end":132},"obj":"UBERON:0002405"},{"id":"T776","span":{"begin":133,"end":146},"obj":"GO:0065007"},{"id":"T777","span":{"begin":222,"end":228},"obj":"UBERON:0002405;GO:0006955"},{"id":"T778","span":{"begin":229,"end":242},"obj":"GO:0065007"},{"id":"T779","span":{"begin":278,"end":282},"obj":"PR:000001393"},{"id":"T780","span":{"begin":294,"end":299},"obj":"PR:000001136"},{"id":"T781","span":{"begin":329,"end":334},"obj":"PR:000001136"},{"id":"T10521","span":{"begin":135,"end":145},"obj":"SP_7"},{"id":"T75385","span":{"begin":223,"end":229},"obj":"UBERON:0002405"},{"id":"T74786","span":{"begin":230,"end":243},"obj":"GO:0065007"},{"id":"T82585","span":{"begin":319,"end":324},"obj":"UBERON:0002405;GO:0006955"}],"attributes":[{"subj":"T774","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T775","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T776","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T777","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T778","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T779","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T780","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T781","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T10521","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T75385","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T74786","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T82585","pred":"source","obj":"LitCovid-PMC-OGER-BB"}]},{"project":"LitCovid-PubTator","denotations":[{"id":"978","span":{"begin":278,"end":282},"obj":"Gene"},{"id":"979","span":{"begin":294,"end":299},"obj":"Gene"},{"id":"980","span":{"begin":329,"end":334},"obj":"Gene"},{"id":"982","span":{"begin":4,"end":12},"obj":"Species"},{"id":"983","span":{"begin":38,"end":48},"obj":"Species"},{"id":"984","span":{"begin":18,"end":27},"obj":"Disease"},{"id":"985","span":{"begin":61,"end":91},"obj":"Disease"}],"attributes":[{"id":"A978","pred":"tao:has_database_id","subj":"978","obj":"Gene:3569"},{"id":"A979","pred":"tao:has_database_id","subj":"979","obj":"Gene:3552"},{"id":"A980","pred":"tao:has_database_id","subj":"980","obj":"Gene:3552"},{"id":"A982","pred":"tao:has_database_id","subj":"982","obj":"Tax:9606"},{"id":"A983","pred":"tao:has_database_id","subj":"983","obj":"Tax:2697049"},{"id":"A984","pred":"tao:has_database_id","subj":"984","obj":"MESH:D011014"},{"id":"A985","pred":"tao:has_database_id","subj":"985","obj":"MESH:D007249"},{"subj":"978","pred":"source","obj":"LitCovid-PubTator"},{"subj":"979","pred":"source","obj":"LitCovid-PubTator"},{"subj":"980","pred":"source","obj":"LitCovid-PubTator"},{"subj":"982","pred":"source","obj":"LitCovid-PubTator"},{"subj":"983","pred":"source","obj":"LitCovid-PubTator"},{"subj":"984","pred":"source","obj":"LitCovid-PubTator"},{"subj":"985","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PD-FMA-UBERON","color":"#ecb493","default":true},{"id":"LitCovid-PD-MONDO","color":"#9a93ec"},{"id":"LitCovid-PD-CHEBI","color":"#a6ec93"},{"id":"LitCovid-PD-GO-BP","color":"#ec93c0"},{"id":"LitCovid-sentences","color":"#93daec"},{"id":"LitCovid-PD-HP","color":"#ece493"},{"id":"LitCovid-PMC-OGER-BB","color":"#ca93ec"},{"id":"LitCovid-PubTator","color":"#93ecb0"}]}]}}