PMC:7172841 / 17054-17464 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T104","span":{"begin":24,"end":33},"obj":"Body_part"},{"id":"T105","span":{"begin":38,"end":46},"obj":"Body_part"},{"id":"T106","span":{"begin":194,"end":228},"obj":"Body_part"},{"id":"T107","span":{"begin":223,"end":228},"obj":"Body_part"}],"attributes":[{"id":"A104","pred":"fma_id","subj":"T104","obj":"http://purl.org/sig/ont/fma/fma62864"},{"id":"A105","pred":"fma_id","subj":"T105","obj":"http://purl.org/sig/ont/fma/fma84050"},{"id":"A106","pred":"fma_id","subj":"T106","obj":"http://purl.org/sig/ont/fma/fma86713"},{"id":"A107","pred":"fma_id","subj":"T107","obj":"http://purl.org/sig/ont/fma/fma68646"}],"text":" profound deficiency of monocytes for cytokine production upon ex vivo stimulation (Giamarellos-Bourboulis et al., 2011). Indeed, production of tumor necrosis factor-α (TNF-α) by LPS-stimulated peripheral blood mononuclear cells (PBMCs) of patients with bacterial CAP classified for immunoparalysis was significantly lower than in patients at an intermediate state (Figure 4 A). That was not the case for patie"}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T13","span":{"begin":205,"end":210},"obj":"Body_part"}],"attributes":[{"id":"A13","pred":"uberon_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/UBERON_0000178"}],"text":" profound deficiency of monocytes for cytokine production upon ex vivo stimulation (Giamarellos-Bourboulis et al., 2011). Indeed, production of tumor necrosis factor-α (TNF-α) by LPS-stimulated peripheral blood mononuclear cells (PBMCs) of patients with bacterial CAP classified for immunoparalysis was significantly lower than in patients at an intermediate state (Figure 4 A). That was not the case for patie"}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T163","span":{"begin":144,"end":149},"obj":"Disease"}],"attributes":[{"id":"A163","pred":"mondo_id","subj":"T163","obj":"http://purl.obolibrary.org/obo/MONDO_0005070"}],"text":" profound deficiency of monocytes for cytokine production upon ex vivo stimulation (Giamarellos-Bourboulis et al., 2011). Indeed, production of tumor necrosis factor-α (TNF-α) by LPS-stimulated peripheral blood mononuclear cells (PBMCs) of patients with bacterial CAP classified for immunoparalysis was significantly lower than in patients at an intermediate state (Figure 4 A). That was not the case for patie"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T163","span":{"begin":24,"end":33},"obj":"http://purl.obolibrary.org/obo/CL_0000576"},{"id":"T164","span":{"begin":194,"end":228},"obj":"http://purl.obolibrary.org/obo/CL_0000842"},{"id":"T165","span":{"begin":194,"end":228},"obj":"http://purl.obolibrary.org/obo/CL_2000001"},{"id":"T166","span":{"begin":375,"end":376},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":" profound deficiency of monocytes for cytokine production upon ex vivo stimulation (Giamarellos-Bourboulis et al., 2011). Indeed, production of tumor necrosis factor-α (TNF-α) by LPS-stimulated peripheral blood mononuclear cells (PBMCs) of patients with bacterial CAP classified for immunoparalysis was significantly lower than in patients at an intermediate state (Figure 4 A). That was not the case for patie"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T68","span":{"begin":179,"end":182},"obj":"Chemical"}],"attributes":[{"id":"A68","pred":"chebi_id","subj":"T68","obj":"http://purl.obolibrary.org/obo/CHEBI_16412"},{"id":"A69","pred":"chebi_id","subj":"T68","obj":"http://purl.obolibrary.org/obo/CHEBI_52603"},{"id":"A70","pred":"chebi_id","subj":"T68","obj":"http://purl.obolibrary.org/obo/CHEBI_89981"}],"text":" profound deficiency of monocytes for cytokine production upon ex vivo stimulation (Giamarellos-Bourboulis et al., 2011). Indeed, production of tumor necrosis factor-α (TNF-α) by LPS-stimulated peripheral blood mononuclear cells (PBMCs) of patients with bacterial CAP classified for immunoparalysis was significantly lower than in patients at an intermediate state (Figure 4 A). That was not the case for patie"}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T22","span":{"begin":38,"end":57},"obj":"http://purl.obolibrary.org/obo/GO_0001816"},{"id":"T23","span":{"begin":150,"end":158},"obj":"http://purl.obolibrary.org/obo/GO_0070265"},{"id":"T24","span":{"begin":150,"end":158},"obj":"http://purl.obolibrary.org/obo/GO_0019835"},{"id":"T25","span":{"begin":150,"end":158},"obj":"http://purl.obolibrary.org/obo/GO_0008219"},{"id":"T26","span":{"begin":150,"end":158},"obj":"http://purl.obolibrary.org/obo/GO_0001906"}],"text":" profound deficiency of monocytes for cytokine production upon ex vivo stimulation (Giamarellos-Bourboulis et al., 2011). Indeed, production of tumor necrosis factor-α (TNF-α) by LPS-stimulated peripheral blood mononuclear cells (PBMCs) of patients with bacterial CAP classified for immunoparalysis was significantly lower than in patients at an intermediate state (Figure 4 A). That was not the case for patie"}

{"project":"LitCovid-sentences","denotations":[{"id":"T135","span":{"begin":122,"end":378},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":" profound deficiency of monocytes for cytokine production upon ex vivo stimulation (Giamarellos-Bourboulis et al., 2011). Indeed, production of tumor necrosis factor-α (TNF-α) by LPS-stimulated peripheral blood mononuclear cells (PBMCs) of patients with bacterial CAP classified for immunoparalysis was significantly lower than in patients at an intermediate state (Figure 4 A). That was not the case for patie"}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T66","span":{"begin":144,"end":149},"obj":"Phenotype"}],"attributes":[{"id":"A66","pred":"hp_id","subj":"T66","obj":"http://purl.obolibrary.org/obo/HP_0002664"}],"text":" profound deficiency of monocytes for cytokine production upon ex vivo stimulation (Giamarellos-Bourboulis et al., 2011). Indeed, production of tumor necrosis factor-α (TNF-α) by LPS-stimulated peripheral blood mononuclear cells (PBMCs) of patients with bacterial CAP classified for immunoparalysis was significantly lower than in patients at an intermediate state (Figure 4 A). That was not the case for patie"}

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T479","span":{"begin":24,"end":33},"obj":"CL:0000576"},{"id":"T480","span":{"begin":130,"end":143},"obj":"GO:1990774"},{"id":"T481","span":{"begin":144,"end":167},"obj":"PR:000000134"},{"id":"T482","span":{"begin":169,"end":174},"obj":"PR:000000134"},{"id":"T483","span":{"begin":179,"end":182},"obj":"CHEBI:16412;CHEBI:16412"},{"id":"T484","span":{"begin":205,"end":210},"obj":"UBERON:0000178;CL:0000842"},{"id":"T485","span":{"begin":211,"end":222},"obj":"CL:0000842;GO:0005634"},{"id":"T486","span":{"begin":223,"end":228},"obj":"CL:0000842"},{"id":"T487","span":{"begin":254,"end":263},"obj":"NCBITaxon:2"},{"id":"T567","span":{"begin":19,"end":32},"obj":"GO:0065007"},{"id":"T568","span":{"begin":47,"end":60},"obj":"GO:1990774"},{"id":"T569","span":{"begin":61,"end":66},"obj":"GO:1990774;PR:000000134"},{"id":"T570","span":{"begin":147,"end":152},"obj":"NCBITaxon:10239"},{"id":"T571","span":{"begin":160,"end":170},"obj":"SP_7"},{"id":"T572","span":{"begin":191,"end":196},"obj":"PR:000001136"},{"id":"T573","span":{"begin":239,"end":248},"obj":"NCBITaxon:2"},{"id":"T574","span":{"begin":292,"end":297},"obj":"UBERON:0002405;GO:0006955"},{"id":"T575","span":{"begin":298,"end":308},"obj":"GO:0006955"},{"id":"T576","span":{"begin":347,"end":352},"obj":"PR:000001136"},{"id":"T577","span":{"begin":393,"end":403},"obj":"SP_7"}],"text":" profound deficiency of monocytes for cytokine production upon ex vivo stimulation (Giamarellos-Bourboulis et al., 2011). Indeed, production of tumor necrosis factor-α (TNF-α) by LPS-stimulated peripheral blood mononuclear cells (PBMCs) of patients with bacterial CAP classified for immunoparalysis was significantly lower than in patients at an intermediate state (Figure 4 A). That was not the case for patie"}

{"project":"2_test","denotations":[{"id":"32320677-21244670-19656937","span":{"begin":115,"end":119},"obj":"21244670"}],"text":" profound deficiency of monocytes for cytokine production upon ex vivo stimulation (Giamarellos-Bourboulis et al., 2011). Indeed, production of tumor necrosis factor-α (TNF-α) by LPS-stimulated peripheral blood mononuclear cells (PBMCs) of patients with bacterial CAP classified for immunoparalysis was significantly lower than in patients at an intermediate state (Figure 4 A). That was not the case for patie"}

{"project":"LitCovid-PubTator","denotations":[{"id":"770","span":{"begin":144,"end":167},"obj":"Gene"},{"id":"771","span":{"begin":169,"end":174},"obj":"Gene"},{"id":"779","span":{"begin":240,"end":248},"obj":"Species"},{"id":"780","span":{"begin":331,"end":339},"obj":"Species"},{"id":"790","span":{"begin":283,"end":298},"obj":"Disease"}],"attributes":[{"id":"A770","pred":"tao:has_database_id","subj":"770","obj":"Gene:7124"},{"id":"A771","pred":"tao:has_database_id","subj":"771","obj":"Gene:7124"},{"id":"A779","pred":"tao:has_database_id","subj":"779","obj":"Tax:9606"},{"id":"A780","pred":"tao:has_database_id","subj":"780","obj":"Tax:9606"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":" profound deficiency of monocytes for cytokine production upon ex vivo stimulation (Giamarellos-Bourboulis et al., 2011). Indeed, production of tumor necrosis factor-α (TNF-α) by LPS-stimulated peripheral blood mononuclear cells (PBMCs) of patients with bacterial CAP classified for immunoparalysis was significantly lower than in patients at an intermediate state (Figure 4 A). That was not the case for patie"}