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PMC:7170415 / 20612-22788 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
304 498-506 Species denotes patients Tax:9606
305 256-265 Disease denotes pneumonia MESH:D011014
306 589-597 Disease denotes COVID-19 MESH:C000657245
307 876-884 Disease denotes COVID-19 MESH:C000657245
308 953-961 Disease denotes COVID-19 MESH:C000657245
309 1012-1021 Disease denotes pneumonia MESH:D011014
310 1083-1091 Disease denotes COVID-19 MESH:C000657245
311 1113-1125 Disease denotes co-infection MESH:D060085
313 1188-1196 Disease denotes COVID-19 MESH:C000657245
329 1345-1363 Gene denotes C-reactive protein Gene:1401
330 1646-1670 Gene denotes alanine aminotransferase Gene:2875
331 1254-1262 Species denotes patients Tax:9606
332 1885-1895 Species denotes SARS–CoV-2 Tax:2697049
333 1967-1975 Species denotes patients Tax:9606
334 1676-1686 Chemical denotes creatinine MESH:D003404
335 1742-1751 Chemical denotes bilirubin MESH:D001663
336 1756-1766 Chemical denotes creatinine MESH:D003404
337 1268-1276 Disease denotes COVID-19 MESH:C000657245
338 1470-1481 Disease denotes lymphopenia MESH:D008231
339 1702-1712 Disease denotes leukopenia MESH:D007970
340 1714-1726 Disease denotes leukocytosis MESH:D007964
341 1920-1941 Disease denotes end-organ dysfunction MESH:C564816
342 1981-1987 Disease denotes sepsis MESH:D018805
343 2118-2126 Disease denotes COVID-19 MESH:C000657245

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T34 195-200 Body_part denotes chest http://purl.org/sig/ont/fma/fma9576
T35 227-232 Body_part denotes chest http://purl.org/sig/ont/fma/fma9576
T36 601-606 Body_part denotes chest http://purl.org/sig/ont/fma/fma9576
T37 764-769 Body_part denotes chest http://purl.org/sig/ont/fma/fma9576
T38 1356-1363 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T39 1576-1587 Body_part denotes erythrocyte http://purl.org/sig/ont/fma/fma62845
T40 1646-1653 Body_part denotes alanine http://purl.org/sig/ont/fma/fma82749
T41 1924-1929 Body_part denotes organ http://purl.org/sig/ont/fma/fma67498

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T17 195-200 Body_part denotes chest http://purl.obolibrary.org/obo/UBERON_0001443
T18 227-232 Body_part denotes chest http://purl.obolibrary.org/obo/UBERON_0001443
T19 601-606 Body_part denotes chest http://purl.obolibrary.org/obo/UBERON_0001443
T20 764-769 Body_part denotes chest http://purl.obolibrary.org/obo/UBERON_0001443
T21 1924-1929 Body_part denotes organ http://purl.obolibrary.org/obo/UBERON_0000062

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T89 256-265 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T90 589-597 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T91 876-884 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T92 953-961 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T93 1012-1021 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T94 1083-1091 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T95 1116-1125 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T96 1188-1196 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T97 1268-1276 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T98 1470-1481 Disease denotes lymphopenia http://purl.obolibrary.org/obo/MONDO_0003783
T99 1702-1712 Disease denotes leukopenia http://purl.obolibrary.org/obo/MONDO_0003785
T100 1885-1889 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T101 2118-2126 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T190 21-26 http://purl.obolibrary.org/obo/UBERON_0000473 denotes Tests
T191 105-110 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T192 146-151 http://purl.obolibrary.org/obo/UBERON_0000473 denotes Tests
T193 195-200 http://www.ebi.ac.uk/efo/EFO_0000965 denotes chest
T194 227-232 http://www.ebi.ac.uk/efo/EFO_0000965 denotes chest
T195 353-354 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T196 366-371 http://purl.obolibrary.org/obo/CLO_0009985 denotes focus
T197 601-606 http://www.ebi.ac.uk/efo/EFO_0000965 denotes chest
T198 635-636 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T199 764-769 http://www.ebi.ac.uk/efo/EFO_0000965 denotes chest
T200 827-831 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T201 835-836 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T202 886-888 http://purl.obolibrary.org/obo/CLO_0001407 denotes 52
T203 1111-1112 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T204 1576-1587 http://purl.obolibrary.org/obo/CL_0000232 denotes erythrocyte
T205 1924-1929 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organ
T206 2103-2104 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T24 1356-1363 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T25 1407-1414 Chemical denotes lactate http://purl.obolibrary.org/obo/CHEBI_24996
T26 1618-1627 Chemical denotes aspartate http://purl.obolibrary.org/obo/CHEBI_132943|http://purl.obolibrary.org/obo/CHEBI_29995|http://purl.obolibrary.org/obo/CHEBI_72314
T29 1646-1653 Chemical denotes alanine http://purl.obolibrary.org/obo/CHEBI_16449
T30 1676-1686 Chemical denotes creatinine http://purl.obolibrary.org/obo/CHEBI_16737
T31 1742-1751 Chemical denotes bilirubin http://purl.obolibrary.org/obo/CHEBI_16990
T32 1756-1766 Chemical denotes creatinine http://purl.obolibrary.org/obo/CHEBI_16737
T33 1997-2006 Chemical denotes biomarker http://purl.obolibrary.org/obo/CHEBI_59163

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T144 0-26 Sentence denotes Ancillary Diagnostic Tests
T145 27-131 Sentence denotes The optimal use of diagnostic imaging, biomarkers, and other nonmicrobiologic tests is rapidly evolving.
T146 133-151 Sentence denotes Radiographic Tests
T147 152-223 Sentence denotes Many centers have evaluated the utility of chest imaging for diagnosis.
T148 224-381 Sentence denotes On chest radiography, bilateral pneumonia is the most frequently reported feature (range, 11.8% to 100%) and is more common than a unilateral focus (49, 50).
T149 382-550 Sentence denotes Computed tomography is regarded as more sensitive than radiography, with several cohort studies reporting that most patients (77.8% to 100%) had ground glass opacities.
T150 551-717 Sentence denotes Other features commonly reported with COVID-19 on chest computed tomography include a peripheral distribution, fine reticular opacities, and vascular thickening (51).
T151 718-894 Sentence denotes Compared with serial nasopharyngeal sampling, chest computed tomography may be more sensitive than an RT-PCR test at a single time point for the diagnosis of COVID-19 (52, 53).
T152 895-1027 Sentence denotes In addition, artificial intelligence may help distinguish COVID-19 from other etiologic agents of community-acquired pneumonia (54).
T153 1028-1159 Sentence denotes However, these findings are not completely specific to COVID-19 and do not exclude a co-infection or an alternative diagnosis (55).
T154 1161-1205 Sentence denotes Biomarkers Associated With COVID-19 Patients
T155 1206-1516 Sentence denotes The most common laboratory features reported in patients with COVID-19 include decreased albumin (75.8% [95% CI, 30.5% to 100%]), elevated C-reactive protein (58.3% [CI, 21.8% to 94.7%]), and elevated lactate dehydrogenase levels (57.0% [CI, 38.0% to 76.0%]), and lymphopenia (43.1% [CI, 18.9% to 67.3%]) (56).
T156 1517-1782 Sentence denotes Other biomarkers that have been reported include increased erythrocyte sedimentation rates; elevated aspartate aminotransferase, alanine aminotransferase, and creatinine kinase levels; leukopenia; leukocytosis; and increased bilirubin and creatinine levels (57–59).
T157 1783-1993 Sentence denotes Such findings are not surprising, because these biomarkers represent an inflammatory host response to SARS–CoV-2 or are early markers of end-organ dysfunction, similar to that seen in patients with sepsis (60).
T158 1994-2176 Sentence denotes No biomarker or combination of biomarkers currently exists that is sensitive or specific enough to establish a diagnosis of COVID-19, or to pragmatically predict its clinical course.

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T3 256-265 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T4 1012-1021 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T5 1470-1481 Phenotype denotes lymphopenia http://purl.obolibrary.org/obo/HP_0001888
T6 1566-1607 Phenotype denotes increased erythrocyte sedimentation rates http://purl.obolibrary.org/obo/HP_0003565
T7 1702-1712 Phenotype denotes leukopenia http://purl.obolibrary.org/obo/HP_0001882
T8 1714-1726 Phenotype denotes leukocytosis http://purl.obolibrary.org/obo/HP_0001974
T9 1732-1751 Phenotype denotes increased bilirubin http://purl.obolibrary.org/obo/HP_0003573
T10 1981-1987 Phenotype denotes sepsis http://purl.obolibrary.org/obo/HP_0100806