> top > docs > PMC:7166305 > annotations

PMC:7166305 JSONTXT

Annnotations TAB JSON ListView MergeView

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T1 22-45 Body_part denotes Low-density lipoprotein http://purl.org/sig/ont/fma/fma63170
T2 253-258 Body_part denotes lipid http://purl.org/sig/ont/fma/fma67264
T3 367-372 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T4 537-560 Body_part denotes low-density lipoprotein http://purl.org/sig/ont/fma/fma63170
T5 562-565 Body_part denotes LDL http://purl.org/sig/ont/fma/fma63170
T6 661-664 Body_part denotes LDL http://purl.org/sig/ont/fma/fma63170
T7 963-966 Body_part denotes LDL http://purl.org/sig/ont/fma/fma63170
T8 1112-1115 Body_part denotes LDL http://purl.org/sig/ont/fma/fma63170
T9 1194-1201 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T10 1273-1276 Body_part denotes LDL http://purl.org/sig/ont/fma/fma63170
T11 1458-1461 Body_part denotes LDL http://purl.org/sig/ont/fma/fma63170
T12 1816-1819 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T13 1909-1916 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T14 1968-1973 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T15 2203-2208 Body_part denotes lungs http://purl.org/sig/ont/fma/fma68877
T16 2266-2277 Body_part denotes pneumocytes http://purl.org/sig/ont/fma/fma62499
T17 2310-2315 Body_part denotes lipid http://purl.org/sig/ont/fma/fma67264
T18 3168-3173 Body_part denotes lipid http://purl.org/sig/ont/fma/fma67264
T19 3822-3828 Body_part denotes kidney http://purl.org/sig/ont/fma/fma7203
T20 4410-4424 Body_part denotes immunoglobulin http://purl.org/sig/ont/fma/fma62871
T21 5030-5036 Body_part denotes Kidney http://purl.org/sig/ont/fma/fma7203
T22 5724-5731 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T23 5793-5806 Body_part denotes interleukin-6 http://purl.org/sig/ont/fma/fma264829
T24 5910-5915 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T25 5951-5956 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T26 6364-6375 Body_part denotes lymphocytes http://purl.org/sig/ont/fma/fma62863
T27 6377-6379 Body_part denotes LY http://purl.org/sig/ont/fma/fma62863
T28 7139-7144 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T29 7226-7231 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T30 7313-7318 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T31 7483-7488 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T32 7573-7578 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T33 7816-7821 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T34 7822-7827 Body_part denotes lipid http://purl.org/sig/ont/fma/fma67264
T35 8016-8039 Body_part denotes low-density lipoprotein http://purl.org/sig/ont/fma/fma63170
T36 8041-8044 Body_part denotes LDL http://purl.org/sig/ont/fma/fma63170
T37 8240-8243 Body_part denotes LDL http://purl.org/sig/ont/fma/fma63170
T38 8463-8487 Body_part denotes high-density lipoprotein http://purl.org/sig/ont/fma/fma63171
T39 8489-8492 Body_part denotes HDL http://purl.org/sig/ont/fma/fma63171
T40 8676-8679 Body_part denotes LDL http://purl.org/sig/ont/fma/fma63170
T41 8681-8684 Body_part denotes HDL http://purl.org/sig/ont/fma/fma63171
T42 8909-8912 Body_part denotes LDL http://purl.org/sig/ont/fma/fma63170
T43 9118-9121 Body_part denotes LDL http://purl.org/sig/ont/fma/fma63170
T44 9127-9130 Body_part denotes HDL http://purl.org/sig/ont/fma/fma63171
T45 9259-9262 Body_part denotes LDL http://purl.org/sig/ont/fma/fma63170
T46 9264-9267 Body_part denotes HDL http://purl.org/sig/ont/fma/fma63171
T47 9971-9974 Body_part denotes LDL http://purl.org/sig/ont/fma/fma63170
T48 9980-9983 Body_part denotes HDL http://purl.org/sig/ont/fma/fma63171
T49 10067-10070 Body_part denotes LDL http://purl.org/sig/ont/fma/fma63170
T50 10072-10075 Body_part denotes HDL http://purl.org/sig/ont/fma/fma63171
T51 10218-10221 Body_part denotes LDL http://purl.org/sig/ont/fma/fma63170
T52 10562-10565 Body_part denotes LDL http://purl.org/sig/ont/fma/fma63170
T53 10567-10570 Body_part denotes HDL http://purl.org/sig/ont/fma/fma63171
T54 10587-10590 Body_part denotes LDL http://purl.org/sig/ont/fma/fma63170
T55 10592-10595 Body_part denotes HDL http://purl.org/sig/ont/fma/fma63171
T56 10881-10884 Body_part denotes LDL http://purl.org/sig/ont/fma/fma63170
T57 11139-11142 Body_part denotes LDL http://purl.org/sig/ont/fma/fma63170
T58 11144-11147 Body_part denotes HDL http://purl.org/sig/ont/fma/fma63171
T59 11368-11371 Body_part denotes LDL http://purl.org/sig/ont/fma/fma63170
T60 11449-11452 Body_part denotes LDL http://purl.org/sig/ont/fma/fma63170
T61 11527-11532 Body_part denotes Organ http://purl.org/sig/ont/fma/fma67498
T62 11701-11706 Body_part denotes lipid http://purl.org/sig/ont/fma/fma67264
T63 11764-11769 Body_part denotes liver http://purl.org/sig/ont/fma/fma7197
T64 11787-11792 Body_part denotes liver http://purl.org/sig/ont/fma/fma7197
T65 11838-11845 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T66 11889-11894 Body_part denotes lipid http://purl.org/sig/ont/fma/fma67264
T67 11998-12007 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T68 12017-12022 Body_part denotes lipid http://purl.org/sig/ont/fma/fma67264
T69 12057-12060 Body_part denotes LDL http://purl.org/sig/ont/fma/fma63170
T70 12111-12114 Body_part denotes LDL http://purl.org/sig/ont/fma/fma63170
T71 12171-12174 Body_part denotes LDL http://purl.org/sig/ont/fma/fma63170
T72 12188-12193 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T73 12407-12411 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T74 12471-12478 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T75 12724-12736 Body_part denotes lipoproteins http://purl.org/sig/ont/fma/fma63169
T76 12908-12911 Body_part denotes LDL http://purl.org/sig/ont/fma/fma63170
T77 13134-13137 Body_part denotes LDL http://purl.org/sig/ont/fma/fma63170
T78 13432-13440 Body_part denotes Appendix http://purl.org/sig/ont/fma/fma14542
T79 13494-13502 Body_part denotes Appendix http://purl.org/sig/ont/fma/fma14542

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 367-372 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T2 2238-2245 Body_part denotes exudate http://purl.obolibrary.org/obo/UBERON_0007780
T3 3822-3828 Body_part denotes kidney http://purl.obolibrary.org/obo/UBERON_0002113
T4 5030-5036 Body_part denotes Kidney http://purl.obolibrary.org/obo/UBERON_0002113
T5 7816-7821 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T6 11527-11532 Body_part denotes Organ http://purl.obolibrary.org/obo/UBERON_0000062
T7 11764-11769 Body_part denotes liver http://purl.obolibrary.org/obo/UBERON_0002107
T8 11787-11792 Body_part denotes liver http://purl.obolibrary.org/obo/UBERON_0002107
T9 12188-12193 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T10 12407-12411 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 106-130 Disease denotes coronavirus disease 2019 http://purl.obolibrary.org/obo/MONDO_0100096
T2 168-192 Disease denotes coronavirus disease 2019 http://purl.obolibrary.org/obo/MONDO_0100096
T3 194-202 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T4 278-286 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T5 416-424 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T6 446-462 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T7 646-655 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T8 791-800 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T9 1624-1648 Disease denotes coronavirus disease 2019 http://purl.obolibrary.org/obo/MONDO_0100096
T10 1650-1658 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T11 1675-1722 Disease denotes severe acute respiratory syndrome coronavirus 2 http://purl.obolibrary.org/obo/MONDO_0100096
T12 1675-1708 Disease denotes severe acute respiratory syndrome http://purl.obolibrary.org/obo/MONDO_0005091
T13 1724-1732 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T14 1786-1790 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T15 1920-1924 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T16 2069-2077 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T17 2335-2343 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T18 2411-2419 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T19 2520-2530 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T20 2812-2816 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T21 2822-2831 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T22 2856-2864 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T23 2878-2886 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T24 3107-3144 Disease denotes chronic obstructive pulmonary disease http://purl.obolibrary.org/obo/MONDO_0005002
T25 3127-3144 Disease denotes pulmonary disease http://purl.obolibrary.org/obo/MONDO_0005275
T26 3146-3150 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T27 3267-3275 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T28 3753-3761 Disease denotes diabetes http://purl.obolibrary.org/obo/MONDO_0005015
T29 3763-3775 Disease denotes hypertension http://purl.obolibrary.org/obo/MONDO_0005044
T30 3777-3801 Disease denotes cardiovascular disorders http://purl.obolibrary.org/obo/MONDO_0004995
T31 3803-3817 Disease denotes hyperlipidemia http://purl.obolibrary.org/obo/MONDO_0021187
T32 3822-3837 Disease denotes kidney diseases http://purl.obolibrary.org/obo/MONDO_0001343|http://purl.obolibrary.org/obo/MONDO_0005240
T34 3951-3959 Disease denotes diarrhea http://purl.obolibrary.org/obo/MONDO_0001673
T35 4687-4695 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T36 4896-4911 Disease denotes Type 2 diabetes http://purl.obolibrary.org/obo/MONDO_0005148
T37 4903-4911 Disease denotes diabetes http://purl.obolibrary.org/obo/MONDO_0005015
T38 4937-4949 Disease denotes Hypertension http://purl.obolibrary.org/obo/MONDO_0005044
T39 4979-5001 Disease denotes Cardiovascular disease http://purl.obolibrary.org/obo/MONDO_0004995
T40 5030-5045 Disease denotes Kidney diseases http://purl.obolibrary.org/obo/MONDO_0001343|http://purl.obolibrary.org/obo/MONDO_0005240
T42 5238-5246 Disease denotes Diarrhea http://purl.obolibrary.org/obo/MONDO_0001673
T43 6199-6208 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T44 6454-6463 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T45 6527-6536 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T46 6762-6773 Disease denotes lymphopenia http://purl.obolibrary.org/obo/MONDO_0003783
T47 6842-6850 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T48 7892-7900 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T49 8158-8167 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T50 8173-8182 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T51 8348-8357 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T52 8591-8600 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T53 8606-8615 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T54 8944-8953 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T55 9149-9157 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T56 9284-9293 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T57 9557-9566 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T58 9819-9828 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T59 10637-10645 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T60 10656-10660 Disease denotes COPD http://purl.obolibrary.org/obo/MONDO_0005002
T61 10744-10752 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T62 10775-10791 Disease denotes viral infections http://purl.obolibrary.org/obo/MONDO_0005108
T63 11288-11300 Disease denotes dyslipidemia http://purl.obolibrary.org/obo/MONDO_0002525
T64 11304-11312 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T65 11717-11725 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T66 11770-11776 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T67 11957-11972 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T68 11963-11972 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T69 12241-12249 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T70 12327-12339 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T71 12398-12406 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T72 12510-12522 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T73 12842-12850 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T74 12923-12931 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T75 12965-12977 Disease denotes dyslipidemia http://purl.obolibrary.org/obo/MONDO_0002525
T76 13033-13041 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T77 13189-13197 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T1 49-50 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T2 204-207 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T3 215-216 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T4 1528-1529 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T5 1737-1740 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T6 1748-1749 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T7 1800-1801 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T8 1820-1825 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T9 1859-1862 http://purl.obolibrary.org/obo/NCBITaxon_9397 denotes bat
T10 1889-1895 http://purl.obolibrary.org/obo/CLO_0001302 denotes 3], [4
T11 1968-1973 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12 2098-2099 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T13 2203-2208 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lungs
T14 2370-2371 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T15 2472-2474 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T16 2707-2708 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T17 2728-2732 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T18 2836-2842 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T19 2984-2986 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T20 3174-3179 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T21 3553-3554 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T22 3570-3578 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test was
T23 3690-3692 http://purl.obolibrary.org/obo/CLO_0001407 denotes 52
T24 3699-3703 http://purl.obolibrary.org/obo/UBERON_0003101 denotes male
T25 3699-3703 http://www.ebi.ac.uk/efo/EFO_0000970 denotes male
T26 3708-3710 http://purl.obolibrary.org/obo/CLO_0001382 denotes 48
T27 3717-3723 http://purl.obolibrary.org/obo/UBERON_0003100 denotes female
T28 3822-3828 http://purl.obolibrary.org/obo/UBERON_0002113 denotes kidney
T29 3822-3828 http://www.ebi.ac.uk/efo/EFO_0000927 denotes kidney
T30 3822-3828 http://www.ebi.ac.uk/efo/EFO_0000929 denotes kidney
T31 3915-3917 http://purl.obolibrary.org/obo/CLO_0054055 denotes 71
T32 4073-4074 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T33 4139-4142 http://purl.obolibrary.org/obo/CL_0000990 denotes CDC
T34 4233-4236 http://purl.obolibrary.org/obo/CL_0000990 denotes CDC
T35 4821-4825 http://purl.obolibrary.org/obo/UBERON_0003101 denotes Male
T36 4821-4825 http://www.ebi.ac.uk/efo/EFO_0000970 denotes Male
T37 4826-4828 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T38 5030-5036 http://purl.obolibrary.org/obo/UBERON_0002113 denotes Kidney
T39 5030-5036 http://www.ebi.ac.uk/efo/EFO_0000927 denotes Kidney
T40 5030-5036 http://www.ebi.ac.uk/efo/EFO_0000929 denotes Kidney
T41 5090-5092 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T42 5172-5174 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T43 5764-5766 http://purl.obolibrary.org/obo/CLO_0001313 denotes 36
T44 5793-5806 http://purl.obolibrary.org/obo/PR_000001393 denotes interleukin-6
T45 5842-5844 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T46 5850-5852 http://purl.obolibrary.org/obo/CLO_0008426 denotes pg
T47 5889-5892 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T48 5908-5915 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T49 5951-5956 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T50 6239-6241 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T51 6284-6286 http://purl.obolibrary.org/obo/CLO_0053799 denotes 45
T52 6345-6347 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T53 6481-6482 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T54 6678-6680 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T55 6722-6723 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T56 6807-6809 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T57 6832-6837 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T58 6912-6917 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T59 7003-7005 http://purl.obolibrary.org/obo/CLO_0008426 denotes pg
T60 7038-7040 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T61 7090-7092 http://purl.obolibrary.org/obo/CLO_0053799 denotes 45
T62 7104-7106 http://purl.obolibrary.org/obo/CLO_0001313 denotes 36
T63 7133-7136 http://purl.obolibrary.org/obo/CLO_0052882 denotes CD3
T64 7133-7136 http://purl.obolibrary.org/obo/CLO_0053434 denotes CD3
T65 7139-7144 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T66 7166-7169 http://purl.obolibrary.org/obo/CLO_0001180 denotes 203
T67 7197-7200 http://purl.obolibrary.org/obo/CLO_0001203 denotes 232
T68 7220-7223 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T69 7226-7231 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T70 7307-7310 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T71 7313-7318 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T72 7391-7394 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T73 7396-7399 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T74 7476-7480 http://purl.obolibrary.org/obo/CLO_0053432 denotes CD19
T75 7483-7488 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T76 7543-7545 http://purl.obolibrary.org/obo/CLO_0001302 denotes 34
T77 7573-7578 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T78 7734-7735 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T79 7751-7755 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T80 8454-8456 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T81 8846-8848 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T82 8888-8889 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T83 9088-9090 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T84 9123-9124 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T85 9132-9133 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T86 9642-9643 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T87 9659-9663 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T88 9738-9740 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T89 10199-10201 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T90 10389-10391 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T91 10414-10416 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T92 10414-10416 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T93 10424-10425 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T94 10457-10458 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T95 11527-11532 http://purl.obolibrary.org/obo/UBERON_0003103 denotes Organ
T96 11762-11763 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T97 11764-11769 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
T98 11764-11769 http://www.ebi.ac.uk/efo/EFO_0000887 denotes liver
T99 11787-11792 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
T100 11787-11792 http://www.ebi.ac.uk/efo/EFO_0000887 denotes liver
T101 11906-11909 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T102 12127-12129 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T103 12145-12146 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T104 12407-12411 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T105 12407-12411 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T106 12663-12664 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T107 12786-12787 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T108 12823-12824 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T109 13215-13216 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T110 13441-13442 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T111 13503-13504 http://purl.obolibrary.org/obo/CLO_0001020 denotes A

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T1 0-6 Chemical denotes Letter http://purl.obolibrary.org/obo/CHEBI_6446
T2 22-45 Chemical denotes Low-density lipoprotein http://purl.obolibrary.org/obo/CHEBI_39026
T3 34-45 Chemical denotes lipoprotein http://purl.obolibrary.org/obo/CHEBI_6495
T4 253-258 Chemical denotes lipid http://purl.obolibrary.org/obo/CHEBI_18059
T5 373-379 Chemical denotes lipids http://purl.obolibrary.org/obo/CHEBI_18059
T6 537-560 Chemical denotes low-density lipoprotein http://purl.obolibrary.org/obo/CHEBI_39026
T7 549-560 Chemical denotes lipoprotein http://purl.obolibrary.org/obo/CHEBI_6495
T8 562-565 Chemical denotes LDL http://purl.obolibrary.org/obo/CHEBI_39026
T9 661-664 Chemical denotes LDL http://purl.obolibrary.org/obo/CHEBI_39026
T10 963-966 Chemical denotes LDL http://purl.obolibrary.org/obo/CHEBI_39026
T11 1112-1115 Chemical denotes LDL http://purl.obolibrary.org/obo/CHEBI_39026
T12 1194-1201 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T13 1273-1276 Chemical denotes LDL http://purl.obolibrary.org/obo/CHEBI_39026
T14 1458-1461 Chemical denotes LDL http://purl.obolibrary.org/obo/CHEBI_39026
T15 1909-1916 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T16 1997-2008 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433
T17 2310-2315 Chemical denotes lipid http://purl.obolibrary.org/obo/CHEBI_18059
T18 2743-2749 Chemical denotes lipids http://purl.obolibrary.org/obo/CHEBI_18059
T19 3168-3173 Chemical denotes lipid http://purl.obolibrary.org/obo/CHEBI_18059
T20 3699-3703 Chemical denotes male http://purl.obolibrary.org/obo/CHEBI_30780
T21 4248-4257 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T22 4268-4275 Chemical denotes arbidol http://purl.obolibrary.org/obo/CHEBI_134730
T23 4277-4286 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T24 4302-4312 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T25 4358-4372 Chemical denotes corticosteroid http://purl.obolibrary.org/obo/CHEBI_50858
T26 4397-4408 Chemical denotes thymalfasin http://purl.obolibrary.org/obo/CHEBI_135915
T27 4485-4491 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T28 5319-5328 Chemical denotes Lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T29 5329-5338 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T30 5494-5500 Chemical denotes Oxygen http://purl.obolibrary.org/obo/CHEBI_15379
T31 5613-5618 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T32 5724-5731 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T33 5808-5810 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T35 6377-6379 Chemical denotes LY http://purl.obolibrary.org/obo/CHEBI_73591
T36 6997-6999 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T38 7675-7680 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T39 7704-7709 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T40 7822-7827 Chemical denotes lipid http://purl.obolibrary.org/obo/CHEBI_18059
T41 8016-8039 Chemical denotes low-density lipoprotein http://purl.obolibrary.org/obo/CHEBI_39026
T42 8028-8039 Chemical denotes lipoprotein http://purl.obolibrary.org/obo/CHEBI_6495
T43 8041-8044 Chemical denotes LDL http://purl.obolibrary.org/obo/CHEBI_39026
T44 8240-8243 Chemical denotes LDL http://purl.obolibrary.org/obo/CHEBI_39026
T45 8463-8487 Chemical denotes high-density lipoprotein http://purl.obolibrary.org/obo/CHEBI_39025
T46 8476-8487 Chemical denotes lipoprotein http://purl.obolibrary.org/obo/CHEBI_6495
T47 8489-8492 Chemical denotes HDL http://purl.obolibrary.org/obo/CHEBI_39025
T48 8676-8679 Chemical denotes LDL http://purl.obolibrary.org/obo/CHEBI_39026
T49 8681-8684 Chemical denotes HDL http://purl.obolibrary.org/obo/CHEBI_39025
T50 8857-8868 Chemical denotes cholesterol http://purl.obolibrary.org/obo/CHEBI_16113
T51 8909-8912 Chemical denotes LDL http://purl.obolibrary.org/obo/CHEBI_39026
T52 9118-9121 Chemical denotes LDL http://purl.obolibrary.org/obo/CHEBI_39026
T53 9127-9130 Chemical denotes HDL http://purl.obolibrary.org/obo/CHEBI_39025
T54 9259-9262 Chemical denotes LDL http://purl.obolibrary.org/obo/CHEBI_39026
T55 9264-9267 Chemical denotes HDL http://purl.obolibrary.org/obo/CHEBI_39025
T56 9971-9974 Chemical denotes LDL http://purl.obolibrary.org/obo/CHEBI_39026
T57 9980-9983 Chemical denotes HDL http://purl.obolibrary.org/obo/CHEBI_39025
T58 10067-10070 Chemical denotes LDL http://purl.obolibrary.org/obo/CHEBI_39026
T59 10072-10075 Chemical denotes HDL http://purl.obolibrary.org/obo/CHEBI_39025
T60 10218-10221 Chemical denotes LDL http://purl.obolibrary.org/obo/CHEBI_39026
T61 10414-10416 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T62 10562-10565 Chemical denotes LDL http://purl.obolibrary.org/obo/CHEBI_39026
T63 10567-10570 Chemical denotes HDL http://purl.obolibrary.org/obo/CHEBI_39025
T64 10587-10590 Chemical denotes LDL http://purl.obolibrary.org/obo/CHEBI_39026
T65 10592-10595 Chemical denotes HDL http://purl.obolibrary.org/obo/CHEBI_39025
T66 10813-10815 Chemical denotes S3 http://purl.obolibrary.org/obo/CHEBI_29388
T67 10881-10884 Chemical denotes LDL http://purl.obolibrary.org/obo/CHEBI_39026
T68 11139-11142 Chemical denotes LDL http://purl.obolibrary.org/obo/CHEBI_39026
T69 11144-11147 Chemical denotes HDL http://purl.obolibrary.org/obo/CHEBI_39025
T70 11368-11371 Chemical denotes LDL http://purl.obolibrary.org/obo/CHEBI_39026
T71 11449-11452 Chemical denotes LDL http://purl.obolibrary.org/obo/CHEBI_39026
T72 11701-11706 Chemical denotes lipid http://purl.obolibrary.org/obo/CHEBI_18059
T73 11838-11845 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T74 11889-11894 Chemical denotes lipid http://purl.obolibrary.org/obo/CHEBI_18059
T75 12017-12022 Chemical denotes lipid http://purl.obolibrary.org/obo/CHEBI_18059
T76 12057-12060 Chemical denotes LDL http://purl.obolibrary.org/obo/CHEBI_39026
T77 12064-12087 Chemical denotes reactive oxygen species http://purl.obolibrary.org/obo/CHEBI_26523
T78 12073-12079 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T79 12111-12114 Chemical denotes LDL http://purl.obolibrary.org/obo/CHEBI_39026
T80 12162-12174 Chemical denotes oxidized LDL http://purl.obolibrary.org/obo/CHEBI_60151
T81 12171-12174 Chemical denotes LDL http://purl.obolibrary.org/obo/CHEBI_39026
T82 12471-12478 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T83 12483-12494 Chemical denotes cholesterol http://purl.obolibrary.org/obo/CHEBI_16113
T84 12724-12736 Chemical denotes lipoproteins http://purl.obolibrary.org/obo/CHEBI_6495
T85 12802-12808 Chemical denotes lipids http://purl.obolibrary.org/obo/CHEBI_18059
T86 12859-12864 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T87 12908-12911 Chemical denotes LDL http://purl.obolibrary.org/obo/CHEBI_39026
T88 13134-13137 Chemical denotes LDL http://purl.obolibrary.org/obo/CHEBI_39026

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T1 446-462 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T2 10775-10791 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infections
T3 11838-11855 http://purl.obolibrary.org/obo/GO_0006412 denotes protein synthesis
T4 11846-11855 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis
T5 11957-11972 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection
T6 12017-12033 http://purl.obolibrary.org/obo/GO_0006629 denotes lipid metabolism
T7 12023-12033 http://purl.obolibrary.org/obo/GO_0008152 denotes metabolism
T8 12111-12124 http://purl.obolibrary.org/obo/GO_0034383 denotes LDL clearance
T9 12327-12339 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T10 12510-12522 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T1 0-21 Sentence denotes Letter to the Editor:
T2 22-130 Sentence denotes Low-density lipoprotein is a potential predictor of poor prognosis in patients with coronavirus disease 2019
T3 132-140 Sentence denotes Abstract
T4 141-151 Sentence denotes Background
T5 152-248 Sentence denotes The pandemic of coronavirus disease 2019 (COVID-19) has become a global threat to public health.
T6 249-298 Sentence denotes The lipid pathophysiology in COVID-19 is unknown.
T7 300-307 Sentence denotes Methods
T8 308-503 Sentence denotes In this retrospective longitudinal study, we monitored the serum lipids in 17 surviving and 4 non-surviving COVID-19 cases prior to their viral infections and duration the entire disease courses.
T9 505-512 Sentence denotes Results
T10 513-801 Sentence denotes In surviving cases, the low-density lipoprotein (LDL) levels decreased significantly on admission as compared with the levels before infection; the LDL levels remained constantly low during the disease progression and resumed to the original levels when patients recovered (pre-infection:
T11 802-830 Sentence denotes 3.5 (3.0–4.4); on admission:
T12 831-868 Sentence denotes 2.8 (2.3–3.1), p < 0.01; progression:
T13 869-894 Sentence denotes 2.5 (2.3–3.0); discharge:
T14 895-935 Sentence denotes 3.6 (2.7–4.1); median (IQR), in mmol/L).
T15 936-1090 Sentence denotes In non-surviving patients, LDL levels showed an irreversible and continuous decrease until death (1.1 (0.9–1.2), p = 0.02 versus the levels on admission).
T16 1091-1209 Sentence denotes The ratio changes of LDL levels inversely correlated with ratio changes of high-sensitivity C-reactive protein levels.
T17 1210-1332 Sentence denotes Logistic regression analysis showed increasing odds of lowered LDL levels associated with disease progression (odds ratio:
T18 1333-1346 Sentence denotes 4.48, 95% IC:
T19 1347-1404 Sentence denotes 1.55–12.92, p = 0.006) and in-hospital death (odds ratio:
T20 1405-1419 Sentence denotes 21.72, 95% IC:
T21 1420-1444 Sentence denotes 1.40–337.54, p = 0.028).
T22 1446-1457 Sentence denotes Conclusions
T23 1458-1580 Sentence denotes LDL levels inversely correlated to disease severities, which could be a predictor for disease progress and poor prognosis.
T24 1582-1597 Sentence denotes 1 Introduction
T25 1598-1607 Sentence denotes Dear Sir,
T26 1608-1785 Sentence denotes The pandemic of coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global threat to public health [1].
T27 1786-1898 Sentence denotes SARS-COV-2 is a single-strand RNA virus with 96.3% sequence identity the bat coronavirus RaTG13 [[2], [3], [4]].
T28 1899-2035 Sentence denotes The spike protein of SARS-COV-2 is responsible for entry of the host cells via binding to surface angiotensin converting enzyme 2 [2,5].
T29 2036-2164 Sentence denotes The estimated mortality rate for COVID-19 is about 2.3%, with a range of 6 to 41 days from the onset of symptoms to death [6,7].
T30 2165-2284 Sentence denotes The prominent pathological changes in lungs include edema, proteinaceous exudate, and multinucleated pneumocytes [8,9].
T31 2285-2344 Sentence denotes We here first report the lipid pathophysiology in COVID-19.
T32 2346-2356 Sentence denotes 2 Methods
T33 2357-2597 Sentence denotes We performed a retrospective longitudinal analysis of COVID-19 patients (n = 21) who were admitted between January 18 and February 8, 2020, into the department of infectious diseases at Zhongnan Hospital of Wuhan University in Wuhan, China.
T34 2598-2675 Sentence denotes The study was approved by the Institutional Review Board at the hospital (No.
T35 2676-2685 Sentence denotes 2020011).
T36 2686-2924 Sentence denotes The patients who had a routine laboratory test including lipids in our hospital between January 9 and 17, 2020 prior to their SARS-CoV2 infection and tested positive for SARS-CoV-2 during the COVID-19 epidemic were included in this study.
T37 2925-3062 Sentence denotes All patients were admitted to our hospital between January 18 and February 8, 2020, and were either discharged or died by March 15, 2020.
T38 3063-3285 Sentence denotes Healthy subjects (n = 31) and patients with chronic obstructive pulmonary disease (COPD, n = 21) who had lipid tests in our hospital between September 2019 to October 2019 were included as normal and non-COVID-19 controls.
T39 3286-3392 Sentence denotes Electronic medical records including demographic, clinical treatment, and laboratory data, were extracted.
T40 3393-3456 Sentence denotes Detailed methods were described in the supplementary materials.
T41 3457-3622 Sentence denotes Data were presented as median (interquartile range, IQR) or mean (standard deviation, s.d.) and a Mann-Whitney U test was used to compare differences between groups.
T42 3624-3634 Sentence denotes 3 Results
T43 3635-3724 Sentence denotes The average age of the patients was 62.5 ± 12.6 years; 52% were male and 48% were female.
T44 3725-3838 Sentence denotes 62% had morbidities such as diabetes, hypertension, cardiovascular disorders, hyperlipidemia, or kidney diseases.
T45 3839-3978 Sentence denotes The onset symptoms of the patients were: fever (86%), cough (95%), fatigue (71%), shortness of breath (43%) and diarrhea (10%) (Table 1a ).
T46 3979-4159 Sentence denotes The severities of the admitted patients were 62% of mild, 19% of severe, and 19% of critical, a classification according to Chinese Center for Disease Control (CDC) guidelines [1].
T47 4160-4437 Sentence denotes Patients received standard treatments based on the guidelines of Chinese CDC, including antiviral remedies (arbidol, lopinavir and ribonavir, interferon α inhalation), anti-inflammatory treatments (corticosteroid), and immune-modulator (thymalfasin, immunoglobulin) (Table 1a).
T48 4438-4562 Sentence denotes Severe and critical cases were given high-flow oxygen, non-invasive or invasive ventilation, depending on their morbidities.
T49 4563-4649 Sentence denotes Seventeen patients recovered and were discharged, while four patients did not survive.
T50 4650-4705 Sentence denotes Table 1a Clinical characteristics of COVID-19 patients.
T51 4706-4713 Sentence denotes No. (%)
T52 4714-4767 Sentence denotes Total (n = 21) Survival (n = 17) Non-survival (n = 4)
T53 4768-4820 Sentence denotes Age, mean (s.d.) 62.5 (12.6) 61.5 (9.5) 79.7 (14.3)⁎
T54 4821-4853 Sentence denotes Male 11 (52.3) 9 (53.9) 2 (50.0)
T55 4854-4894 Sentence denotes Comorbidities 13 (61.9) 9 (53.9) 4 (100)
T56 4895-4935 Sentence denotes  Type 2 diabetes 3 (14.3) 3 (17.6) 0 (0)
T57 4936-4977 Sentence denotes  Hypertension 10 (47.6) 8 (35.3) 2 (50.0)
T58 4978-5028 Sentence denotes  Cardiovascular disease 5 (23.8) 3 (17.6) 2 (50.0)
T59 5029-5067 Sentence denotes  Kidney diseases 1 (4.8) 1 (5.8) 0 (0)
T60 5068-5082 Sentence denotes Onset symptoms
T61 5083-5117 Sentence denotes  Fever 18 (85.7) 14 (82.3) 4 (100)
T62 5118-5152 Sentence denotes  Cough 20 (95.2) 16 (94.1) 4 (100)
T63 5153-5189 Sentence denotes  Fatigue 15 (71.4) 11 (64.7) 4 (100)
T64 5190-5236 Sentence denotes  Shortness of breath 9 (42.8) 5 (29.4) 4 (100)
T65 5237-5269 Sentence denotes  Diarrhea 2 (9.5) 2 (11.7) 0 (0)
T66 5270-5279 Sentence denotes Treatment
T67 5280-5317 Sentence denotes  Arbidol 15 (71.4) 12 (70.6) 3 (75.0)
T68 5318-5365 Sentence denotes  Lopinavir/ritonavir 7 (33.3) 4 (23.5) 3 (75.0)
T69 5366-5415 Sentence denotes  Interferon inhalation 7 (33.3) 4 (23.5) 3 (75.0)
T70 5416-5455 Sentence denotes  Corticosteroid 3 (14.3) 3 (17.6) 0 (0)
T71 5456-5492 Sentence denotes  Thymalfasin 6 (28.6) 6 (35.3) 0 (0)
T72 5493-5526 Sentence denotes  Oxygen 8 (38.1) 4 (23.5) 4 (100)
T73 5527-5573 Sentence denotes  Mechanical ventilation 4 (19.0) 0 (0) 4 (100)
T74 5574-5633 Sentence denotes ⁎ p < 0.05, as compared to the patient group that survived.
T75 5634-6049 Sentence denotes In the stage of disease progression, there were significantly higher levels of C-reactive protein (CRP) (78 (28–134) versus 15 (7–36), in mg/L, p = 0.042) and interleukin-6 (IL-6) (195 (127–280) versus 12 (4–18), in pg/ml, p < 0.001), but lower levels of CD8+ subpopulation T cells (33 (23–135) versus 273 (122–377), cells/μl, p = 0.016) in non-surviving patients as compared with the patients survived (Table 1b ).
T76 6050-6209 Sentence denotes Furthermore, in surviving patients, increases in levels of high-sensitivity CRP (hsCRP) were significantly associated with the disease severity (pre-infection:
T77 6210-6238 Sentence denotes 1.2 (0.7–5.9); on admission:
T78 6239-6274 Sentence denotes 11 (5.9–26), p < 0.02; progression:
T79 6275-6299 Sentence denotes 9.8 (5.3–45); discharge:
T80 6300-6349 Sentence denotes 2.2 (1.2–7.0), in mg/L) (Supplementary Table S1).
T81 6350-6537 Sentence denotes The number of lymphocytes (LY) decreased significantly at the time of admission as compared with before infection; it did not show a full recovery at the time of discharge (pre-infection:
T82 6538-6566 Sentence denotes 1.6 (1.4–2.2); on admission:
T83 6567-6604 Sentence denotes 1.0 (0.8–1.5), p < 0.02; progression:
T84 6605-6630 Sentence denotes 0.9 (0.5–1.4); discharge:
T85 6631-6682 Sentence denotes 1.2 (0.8–1.9), in x109/L) (Supplementary Table S1).
T86 6683-6811 Sentence denotes In patients did not survive, there was a continuous increase in hsCRP level or lymphopenia until death (Supplementary Table S1).
T87 6812-6900 Sentence denotes Table 1b Laboratory tests for COVID-19 patients during the stage of disease progression.
T88 6901-6941 Sentence denotes Laboratory tests Reference value No. (%)
T89 6942-6996 Sentence denotes Total (n = 21) Survival (n = 17) Non-survival(n = 4) p
T90 6997-7069 Sentence denotes IL-6 (pg/ml) 0.1–2.9 15 (8–79, 19) 12 (4–18, 15) 195 (127–280, 4) <0.001
T91 7070-7132 Sentence denotes CRP (mg/L) <4 20 (7–45, 21) 15 (7–36, 17) 78 (28–134, 4) 0.042
T92 7133-7219 Sentence denotes CD3+ (cells/μl) 805 to 4459 562 (203–939, 19) 680 (303–945, 15) 232 (129–340, 4) 0.062
T93 7220-7306 Sentence denotes CD4+ (cells/μl) 345 to 2350 297 (135–557, 19) 416 (172–557, 15) 168 (108–250, 4) 0.121
T94 7307-7390 Sentence denotes CD8+ (cells/μl) 345 to 2350 166 (50–336, 19) 273 (122–377, 15) 33 (23–135, 4) 0.016
T95 7391-7475 Sentence denotes CD4+/CD8+ ratio 0.96–2.05 1.7 (1.2–3.1, 19) 1.6 (1.3–2.4, 15) 5.0 (2.0–6.2, 4) 0.079
T96 7476-7559 Sentence denotes CD19+ (cells/μl) 240 to 1317 104 (49–174, 19) 104 (49–236, 15) 84 (34–134, 4) 0.650
T97 7560-7650 Sentence denotes CD16+/CD56+ (cells/μl) 210 to 1514 164 (49–252, 19) 168 (106–252, 15) 33 (10–223, 4) 0.124
T98 7651-7756 Sentence denotes P value is compared the group that survived with the group that did not survive by a Mann-Whitney U test.
T99 7757-7794 Sentence denotes Data is presented as median (IQR, n).
T100 7795-7950 Sentence denotes We next analyzed the serum lipid levels (in mmol/L) of the patients before they were infected by SARS-CoV-2 and during their entire courses of the disease.
T101 7951-8011 Sentence denotes The average timeline of disease course was shown in Fig. 1 .
T102 8012-8183 Sentence denotes The low-density lipoprotein (LDL) levels in all patients showed significant decreases at the time on admission as compared to the levels prior to infection (pre-infection:
T103 8184-8209 Sentence denotes 3.5 (3.0–4.4); admission:
T104 8210-8458 Sentence denotes 2.8 (2.3–3.1), p < 0.01); the LDL levels remained relatively low during the treatment (2.5 (2.3–3.0)) and returned to the levels prior to infection in patients that survived by the time of discharge (3.6 (2.7–4.1)) (Fig. 1, Supplementary Table S1).
T105 8459-8616 Sentence denotes The high-density lipoprotein (HDL) levels also showed significant decreases at the time on admission as compared to levels prior to infection (pre-infection:
T106 8617-8642 Sentence denotes 1.4 (1.0–1.8); admission:
T107 8643-8668 Sentence denotes 1.1 (0.8–1.4), p = 0.03).
T108 8669-8775 Sentence denotes Unlike LDL, HDL levels remained relatively low during the treatment stage and after recovery (progression:
T109 8776-8801 Sentence denotes 1.2 (1.0–1.4); discharge:
T110 8802-8850 Sentence denotes 1.0 (1.0–1.4)) (Fig. 1, Supplementary Table S1).
T111 8851-8954 Sentence denotes Total cholesterol (TC) levels showed a pattern similar to LDL during the disease course (pre-infection:
T112 8955-8980 Sentence denotes 5.2 (4.6–6.5); admission:
T113 8981-9018 Sentence denotes 3.5 (3.3–4.1), p < 0.01; progression:
T114 9019-9044 Sentence denotes 4.5 (4.0–4.8); discharge:
T115 9045-9092 Sentence denotes 5.2 (4.4–6.1); Fig. 1, Supplementary Table S1).
T116 9093-9196 Sentence denotes Fig. 1 Ratio changes for LDL (A), HDL (B) and TC (C) in COVID-19 patients during the course of disease.
T117 9197-9315 Sentence denotes For each data point, the ratio is normalized to the levels of LDL, HDL and TC prior to infection for the same patient.
T118 9316-9406 Sentence denotes The days listed are the duration (median (IQR)) for each period during the disease course.
T119 9407-9447 Sentence denotes The date on admission is set as “day 0”.
T120 9448-9664 Sentence denotes Data is presented as “mean ± 95% confidence interval”. # indicates p < 0.05 as compared to the levels of pre-infection stage, and * indicates p < 0.05 as compared to the levels on admission, by a Mann-Whitney U test.
T121 9665-9741 Sentence denotes The sample actual values at each stage are listed in Supplementary Table S1.
T122 9742-9850 Sentence denotes The ratios of hsCRP at each time point are normalized to the levels prior to infection in the same patients.
T123 9851-10062 Sentence denotes Pearson correlation coefficient analysis show the ratios of hsCRP significantly inversely correlated with the ratios of LDL (D), HDL (E) and TC (F) during the disease course; n = 33 data pairs for each analysis.
T124 10063-10203 Sentence denotes The LDL, HDL and TC levels in the patients that did not survive (n = 4) decreased continuously until death (Fig. 1, Supplementary Table S1).
T125 10204-10393 Sentence denotes Particularly, LDL levels showed an irreversible decrease by the most percentage (~60%) until death (1.1 (0.9–1.2), p = 0.02 versus the levels on admission) (Fig. 1, Supplementary Table S1).
T126 10394-10586 Sentence denotes Supplementary table S2 showed a timeline of disease course for a non-surviving patient, from hospital admission to death, with continuous and irreversible decreases in LDL, HDL, and TC levels.
T127 10587-10817 Sentence denotes LDL, HDL and TC levels in normal subjects and non-COVID-19 patients (COPD) control groups did not show significant difference as compared with the levels in COVID-19 patients before their viral infections (Supplementary Table S3).
T128 10818-10970 Sentence denotes Logistic regression analysis showed increasing odds of lowered LDL levels associated with disease progression (Chi-Square = 7.49; p = 0.006; odds ratio:
T129 10971-10984 Sentence denotes 4.48, 95% IC:
T130 10985-11077 Sentence denotes 1.55–12.92, p = 0.006) and in-hospital mortality (Chi-Square = 10.87; p = 0.001; odds ratio:
T131 11078-11092 Sentence denotes 21.72, 95% IC:
T132 11093-11117 Sentence denotes 1.40–337.54, p = 0.028).
T133 11118-11243 Sentence denotes The ratio changes of LDL, HDL and TC inversely correlated with the ratio changes of hsCRP during the disease course (Fig. 1).
T134 11245-11258 Sentence denotes 4 Discussion
T135 11259-11448 Sentence denotes In this study, we report the dyslipidemia in COVID-19 patients and demonstrate that the degrees of decreased LDL levels have high odds associated with severity and mortality of the disease.
T136 11449-11647 Sentence denotes LDL, together with other risk factors [10] such as older age, high Sequential Organ Failure Assessment, and d-dimer, may aid physicians in identifying patients with poor prognosis at an early phase.
T137 11648-11735 Sentence denotes There are several possible explanations for aberrant lipid levels in COVID-19 patients.
T138 11736-11777 Sentence denotes First, it may result from a liver injury.
T139 11778-11948 Sentence denotes Although liver functions only exhibit mild abnormalities in protein synthesis (Supplementary Table 1), whether lipid biogenesis has been impaired is yet to be determined.
T140 11949-12144 Sentence denotes Second, viral infection induced pro-inflammatory cytokines modulate lipid metabolism including oxidation of LDL by reactive oxygen species singling to facilitate LDL clearance [[11], [12], [13]].
T141 12145-12233 Sentence denotes A measurement of oxidized LDL in patient's serum will aid in determining this mechanism.
T142 12234-12340 Sentence denotes Third, COVID-19 patients may have an increased vascular permeability caused by viral-induced inflammation.
T143 12341-12426 Sentence denotes Exudates have been found evidently in the early phase of COVID-19 lung pathology [8].
T144 12427-12618 Sentence denotes Exudative fluids, containing high levels of protein and cholesterol, are caused by inflammation-related vascular permeability [14,15], which may be one possible mechanism underlying our data.
T145 12619-12755 Sentence denotes The major limitations of this study include a small size of patients and lack of information of specific lipoproteins and oxidized LDLs.
T146 12756-12941 Sentence denotes Another limitation is lack of a data set with lipids monitoring on a hospitalized non-COVID-19 disease group to further address the specificity between LDL levels and COVID-19 severity.
T147 12942-13089 Sentence denotes We also posit that the dyslipidemia plays an important role in pathological development of COVID-19, which mechanism needs an urgent investigation.
T148 13090-13272 Sentence denotes In conclusion, our results demonstrate that LDL decrease is associated with pathological course of COVID-19, which can serve a factor to access the disease progression and mortality.
T149 13274-13307 Sentence denotes Declaration of competing interest
T150 13308-13430 Sentence denotes The authors do not have any professional and financial affiliations that may be perceived to have biased the presentation.
T151 13432-13462 Sentence denotes Appendix A Supplementary data
T152 13463-13610 Sentence denotes Supplementary methods and data Appendix A Supplementary data to this article can be found online at https://doi.org/10.1016/j.metabol.2020.154243.

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T1 2217-2222 Phenotype denotes edema http://purl.obolibrary.org/obo/HP_0000969
T2 3107-3144 Phenotype denotes chronic obstructive pulmonary disease http://purl.obolibrary.org/obo/HP_0006510
T3 3146-3150 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T4 3763-3775 Phenotype denotes hypertension http://purl.obolibrary.org/obo/HP_0000822
T5 3803-3817 Phenotype denotes hyperlipidemia http://purl.obolibrary.org/obo/HP_0003077
T6 3822-3837 Phenotype denotes kidney diseases http://purl.obolibrary.org/obo/HP_0000112
T7 3880-3885 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T8 3893-3898 Phenotype denotes cough http://purl.obolibrary.org/obo/HP_0012735
T9 3906-3913 Phenotype denotes fatigue http://purl.obolibrary.org/obo/HP_0012378
T10 3921-3940 Phenotype denotes shortness of breath http://purl.obolibrary.org/obo/HP_0002098
T11 3951-3959 Phenotype denotes diarrhea http://purl.obolibrary.org/obo/HP_0002014
T12 4896-4911 Phenotype denotes Type 2 diabetes http://purl.obolibrary.org/obo/HP_0005978
T13 4937-4949 Phenotype denotes Hypertension http://purl.obolibrary.org/obo/HP_0000822
T14 4979-5001 Phenotype denotes Cardiovascular disease http://purl.obolibrary.org/obo/HP_0001626
T15 5030-5045 Phenotype denotes Kidney diseases http://purl.obolibrary.org/obo/HP_0000112
T16 5084-5089 Phenotype denotes Fever http://purl.obolibrary.org/obo/HP_0001945
T17 5119-5124 Phenotype denotes Cough http://purl.obolibrary.org/obo/HP_0012735
T18 5154-5161 Phenotype denotes Fatigue http://purl.obolibrary.org/obo/HP_0012378
T19 5191-5210 Phenotype denotes Shortness of breath http://purl.obolibrary.org/obo/HP_0002098
T20 5238-5246 Phenotype denotes Diarrhea http://purl.obolibrary.org/obo/HP_0002014
T21 6762-6773 Phenotype denotes lymphopenia http://purl.obolibrary.org/obo/HP_0001888
T22 10656-10660 Phenotype denotes COPD http://purl.obolibrary.org/obo/HP_0006510
T23 11288-11300 Phenotype denotes dyslipidemia http://purl.obolibrary.org/obo/HP_0003119
T24 11358-11371 Phenotype denotes decreased LDL http://purl.obolibrary.org/obo/HP_0003563
T25 12965-12977 Phenotype denotes dyslipidemia http://purl.obolibrary.org/obo/HP_0003119

LitCovid-PMC-OGER-BB

Id Subject Object Predicate Lexical cue
T1 106-117 NCBITaxon:11118 denotes coronavirus
T2 168-179 NCBITaxon:11118 denotes coronavirus
T3 194-202 SP_7 denotes COVID-19
T4 253-258 CHEBI:18059;CHEBI:18059 denotes lipid
T5 278-286 SP_7 denotes COVID-19
T6 367-372 UBERON:0001977 denotes serum
T7 373-379 CHEBI:18059;CHEBI:18059 denotes lipids
T8 416-424 SP_7 denotes COVID-19
T9 446-451 NCBITaxon:10239 denotes viral
T10 1027-1032 GO:0016265 denotes death
T11 1183-1201 PR:000005897 denotes C-reactive protein
T12 1386-1391 GO:0016265 denotes death
T13 1624-1635 NCBITaxon:11118 denotes coronavirus
T14 1650-1658 SP_7 denotes COVID-19
T15 1675-1687 SP_7 denotes severe acute
T16 1688-1699 SP_7;UBERON:0001004 denotes respiratory
T17 1700-1722 SP_7 denotes syndrome coronavirus 2
T18 1724-1734 SP_7 denotes SARS-CoV-2
T19 1786-1796 SP_7 denotes SARS-COV-2
T20 1802-1815 SO:0001199 denotes single-strand
T21 1816-1819 BV_22 denotes RNA
T22 1820-1825 BV_22;NCBITaxon:10239 denotes virus
T23 1859-1862 SP_2 denotes bat
T24 1863-1874 NCBITaxon:11118 denotes coronavirus
T25 1920-1930 SP_7 denotes SARS-COV-2
T26 1950-1958 GO:0035376 denotes entry of
T27 1989-1996 GO:0009986 denotes surface
T28 1997-2028 PG_10;PR:000003622 denotes angiotensin converting enzyme 2
T29 2069-2077 SP_7 denotes COVID-19
T30 2152-2157 GO:0016265 denotes death
T31 2203-2208 UBERON:0000170 denotes lungs
T32 2251-2265 GO:0005634;CL:0000228 denotes multinucleated
T33 2266-2277 CL:0000322 denotes pneumocytes
T34 2310-2315 CHEBI:18059;CHEBI:18059 denotes lipid
T35 2335-2343 SP_7 denotes COVID-19
T36 2411-2419 SP_7 denotes COVID-19
T37 2743-2749 CHEBI:18059;CHEBI:18059 denotes lipids
T38 2812-2821 SP_7 denotes SARS-CoV2
T39 2856-2866 SP_7 denotes SARS-CoV-2
T40 2878-2886 SP_7 denotes COVID-19
T41 3039-3043 GO:0016265 denotes died
T42 3127-3136 UBERON:0002048 denotes pulmonary
T43 3168-3173 CHEBI:18059;CHEBI:18059 denotes lipid
T44 3267-3275 SP_7 denotes COVID-19
T45 3777-3791 UBERON:0004535 denotes cardiovascular
T46 3822-3828 UBERON:0002113 denotes kidney
T47 3934-3940 UBERON:0002048 denotes breath
T48 4268-4275 CHEBI:2511;DG_49;CHEBI:2511 denotes arbidol
T49 4277-4286 CHEBI:31781;DG_23;CHEBI:31781 denotes lopinavir
T50 4302-4314 PR:000024938 denotes interferon α
T51 4358-4372 CHEBI:50858;CHEBI:50858 denotes corticosteroid
T52 4379-4385 UBERON:0002405 denotes immune
T53 4410-4424 GO:0019814 denotes immunoglobulin
T54 4687-4695 SP_7 denotes COVID-19
T55 4979-4993 UBERON:0004535 denotes Cardiovascular
T56 5030-5036 UBERON:0002113 denotes Kidney
T57 5281-5291 DG_49 denotes Arbidol 15
T58 5319-5328 DG_23 denotes Lopinavir
T59 5329-5340 DG_30 denotes ritonavir 7
T60 5417-5433 CHEBI:50858;CHEBI:50858 denotes Corticosteroid 3
T62 5713-5731 PR:000005897 denotes C-reactive protein
T63 5793-5806 PR:000001393 denotes interleukin-6
T64 5808-5812 PR:000001393 denotes IL-6
T65 6364-6375 CL:0000542 denotes lymphocytes
T66 6780-6785 GO:0016265 denotes death
T67 6842-6850 SP_7 denotes COVID-19
T68 6999-7001 PR:Q84LH8 denotes -6
T69 7556-7564 PR:000001483 denotes 650 CD16
T70 7566-7570 PR:000001024 denotes CD56
T72 7816-7821 UBERON:0001977 denotes serum
T73 7822-7827 CHEBI:18059;CHEBI:18059 denotes lipid
T74 7892-7902 SP_7 denotes SARS-CoV-2
T75 8857-8868 CHEBI:16113;CHEBI:16113 denotes cholesterol
T76 9149-9157 SP_7 denotes COVID-19
T78 10164-10169 GO:0016265 denotes death
T79 10297-10302 GO:0016265 denotes death
T80 10509-10514 GO:0016265 denotes death
T81 10637-10645 SP_7 denotes COVID-19
T82 10744-10752 SP_7 denotes COVID-19
T83 10775-10780 NCBITaxon:10239 denotes viral
T84 11304-11312 SP_7 denotes COVID-19
T85 11527-11532 UBERON:0000062 denotes Organ
T86 11701-11706 CHEBI:18059;CHEBI:18059 denotes lipid
T87 11717-11725 SP_7 denotes COVID-19
T88 11764-11769 UBERON:0002107 denotes liver
T89 11787-11792 UBERON:0002107 denotes liver
T90 11838-11855 GO:0006412 denotes protein synthesis
T91 11889-11894 CHEBI:18059;CHEBI:18059;GO:0006629 denotes lipid
T92 11895-11905 GO:0006629 denotes biogenesis
T93 11957-11962 NCBITaxon:10239 denotes viral
T94 12008-12016 GO:0065007 denotes modulate
T95 12017-12022 CHEBI:18059;CHEBI:18059;GO:0006629 denotes lipid
T96 12023-12033 GO:0006629 denotes metabolism
T97 12044-12053 MOP:0000568 denotes oxidation
T98 12064-12087 CHEBI:26523;CHEBI:26523 denotes reactive oxygen species
T99 12162-12170 MOP:0000568 denotes oxidized
T100 12188-12193 UBERON:0001977 denotes serum
T101 12241-12249 SP_7 denotes COVID-19
T102 12313-12318 NCBITaxon:10239 denotes viral
T103 12398-12406 SP_7 denotes COVID-19
T104 12407-12411 UBERON:0002048 denotes lung
T105 12437-12443 UBERON:0006314 denotes fluids
T106 12483-12494 CHEBI:16113;CHEBI:16113 denotes cholesterol
T107 12741-12749 MOP:0000568 denotes oxidized
T108 12802-12808 CHEBI:18059;CHEBI:18059 denotes lipids
T109 12842-12850 SP_7 denotes COVID-19
T110 12923-12931 SP_7 denotes COVID-19
T111 13033-13041 SP_7 denotes COVID-19
T112 13189-13197 SP_7 denotes COVID-19
T73685 106-117 NCBITaxon:11118 denotes coronavirus
T73962 168-179 NCBITaxon:11118 denotes coronavirus
T78212 194-202 SP_7 denotes COVID-19
T1063 253-258 CHEBI:18059;CHEBI:18059 denotes lipid
T45256 278-286 SP_7 denotes COVID-19
T57491 367-372 UBERON:0001977 denotes serum
T37482 373-379 CHEBI:18059;CHEBI:18059 denotes lipids
T44268 416-424 SP_7 denotes COVID-19
T57245 446-451 NCBITaxon:10239 denotes viral
T30280 1027-1032 GO:0016265 denotes death
T58122 1183-1201 PR:000005897 denotes C-reactive protein
T71297 1386-1391 GO:0016265 denotes death
T28619 1624-1635 NCBITaxon:11118 denotes coronavirus
T93676 1650-1658 SP_7 denotes COVID-19
T31083 1675-1687 SP_7 denotes severe acute
T73727 1688-1699 SP_7;UBERON:0001004 denotes respiratory
T18747 1700-1722 SP_7 denotes syndrome coronavirus 2
T1926 1724-1734 SP_7 denotes SARS-CoV-2
T5796 1786-1796 SP_7 denotes SARS-COV-2
T82336 1802-1815 SO:0001199 denotes single-strand
T68013 1816-1819 BV_22 denotes RNA
T54677 1820-1825 BV_22;NCBITaxon:10239 denotes virus
T97710 1859-1862 SP_2 denotes bat
T32171 1863-1874 NCBITaxon:11118 denotes coronavirus
T77527 1920-1930 SP_7 denotes SARS-COV-2
T2818 1950-1958 GO:0035376 denotes entry of
T36797 1989-1996 GO:0009986 denotes surface
T77301 1997-2028 PG_10;PR:000003622 denotes angiotensin converting enzyme 2
T84197 2069-2077 SP_7 denotes COVID-19
T10479 2152-2157 GO:0016265 denotes death
T22579 2203-2208 UBERON:0000170 denotes lungs
T53721 2251-2265 GO:0005634;CL:0000228 denotes multinucleated
T48123 2266-2277 CL:0000322 denotes pneumocytes
T82206 2310-2315 CHEBI:18059;CHEBI:18059 denotes lipid
T30426 2335-2343 SP_7 denotes COVID-19
T57759 2411-2419 SP_7 denotes COVID-19
T28678 2743-2749 CHEBI:18059;CHEBI:18059 denotes lipids
T59752 2812-2821 SP_7 denotes SARS-CoV2
T32600 2856-2866 SP_7 denotes SARS-CoV-2
T33088 2878-2886 SP_7 denotes COVID-19
T63413 3039-3043 GO:0016265 denotes died
T21380 3127-3136 UBERON:0002048 denotes pulmonary
T57045 3168-3173 CHEBI:18059;CHEBI:18059 denotes lipid
T45348 3267-3275 SP_7 denotes COVID-19
T8077 3777-3791 UBERON:0004535 denotes cardiovascular
T60693 3822-3828 UBERON:0002113 denotes kidney
T9803 3934-3940 UBERON:0002048 denotes breath
T56327 4268-4275 CHEBI:2511;DG_49;CHEBI:2511 denotes arbidol
T71601 4277-4286 CHEBI:31781;DG_23;CHEBI:31781 denotes lopinavir
T81588 4302-4314 PR:000024938 denotes interferon α
T72727 4358-4372 CHEBI:50858;CHEBI:50858 denotes corticosteroid
T85122 4379-4385 UBERON:0002405 denotes immune
T13301 4410-4424 GO:0019814 denotes immunoglobulin
T10728 4687-4695 SP_7 denotes COVID-19
T4676 4979-4993 UBERON:0004535 denotes Cardiovascular
T31009 5030-5036 UBERON:0002113 denotes Kidney
T31002 5281-5291 DG_49 denotes Arbidol 15
T45645 5319-5328 DG_23 denotes Lopinavir
T6788 5329-5340 DG_30 denotes ritonavir 7
T70091 5417-5433 CHEBI:50858;CHEBI:50858 denotes Corticosteroid 3
T23504 5838-5840 PR:Q84LH8 denotes (
T9285 6354-6362 PR:000001483 denotes number o
T21132 6364-6368 PR:000001024 denotes lymp
T71 6617-6625 SP_7 denotes ); disch
T24283 6842-6847 UBERON:0001977 denotes COVID
T55143 6848-6852 CHEBI:18059;CHEBI:18059 denotes 19 p
T37903 6917-6927 SP_7 denotes Reference
T51291 7883-7894 CHEBI:16113;CHEBI:16113 denotes ected by SA
T27254 8173-8181 SP_7 denotes infectio
T77 9149-9157 SP_7 denotes COVID-19
T38577 10164-10169 GO:0016265 denotes death
T80979 10297-10302 GO:0016265 denotes death
T59342 10509-10514 GO:0016265 denotes death
T45173 10637-10645 SP_7 denotes COVID-19
T71757 10744-10752 SP_7 denotes COVID-19
T14996 10775-10780 NCBITaxon:10239 denotes viral
T4073 11304-11312 SP_7 denotes COVID-19
T16206 11527-11532 UBERON:0000062 denotes Organ
T29276 11701-11706 CHEBI:18059;CHEBI:18059 denotes lipid
T86953 11717-11725 SP_7 denotes COVID-19
T66578 11764-11769 UBERON:0002107 denotes liver
T59820 11787-11792 UBERON:0002107 denotes liver
T39721 11838-11855 GO:0006412 denotes protein synthesis
T98783 11889-11894 CHEBI:18059;CHEBI:18059;GO:0006629 denotes lipid
T20661 11895-11905 GO:0006629 denotes biogenesis
T69035 11957-11962 NCBITaxon:10239 denotes viral
T93923 12008-12016 GO:0065007 denotes modulate
T12966 12017-12022 CHEBI:18059;CHEBI:18059;GO:0006629 denotes lipid
T21308 12023-12033 GO:0006629 denotes metabolism
T93593 12044-12053 MOP:0000568 denotes oxidation
T13553 12064-12087 CHEBI:26523;CHEBI:26523 denotes reactive oxygen species
T67219 12162-12170 MOP:0000568 denotes oxidized
T27393 12188-12193 UBERON:0001977 denotes serum
T797 12241-12249 SP_7 denotes COVID-19
T67111 12313-12318 NCBITaxon:10239 denotes viral
T17497 12398-12406 SP_7 denotes COVID-19
T9266 12407-12411 UBERON:0002048 denotes lung
T41883 12437-12443 UBERON:0006314 denotes fluids
T46522 12483-12494 CHEBI:16113;CHEBI:16113 denotes cholesterol
T34943 12741-12749 MOP:0000568 denotes oxidized
T13227 12802-12808 CHEBI:18059;CHEBI:18059 denotes lipids
T98724 12842-12850 SP_7 denotes COVID-19
T33821 12923-12931 SP_7 denotes COVID-19
T1735 13033-13041 SP_7 denotes COVID-19
T75143 13189-13197 SP_7 denotes COVID-19

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
2 92-100 Species denotes patients Tax:9606
3 106-130 Disease denotes coronavirus disease 2019 MESH:C000657245
7 168-192 Disease denotes coronavirus disease 2019 MESH:C000657245
8 194-202 Disease denotes COVID-19 MESH:C000657245
9 278-286 Disease denotes COVID-19 MESH:C000657245
13 373-379 Chemical denotes lipids MESH:D008055
14 416-424 Disease denotes COVID-19 MESH:C000657245
15 446-462 Disease denotes viral infections MESH:D001102
23 1183-1201 Gene denotes C-reactive protein Gene:1401
24 767-775 Species denotes patients Tax:9606
25 953-961 Species denotes patients Tax:9606
26 646-655 Disease denotes infection MESH:D007239
27 791-800 Disease denotes infection MESH:D007239
28 1027-1032 Disease denotes death MESH:D003643
29 1386-1391 Disease denotes death MESH:D003643
45 1903-1908 Gene denotes spike Gene:43740568
46 1997-2028 Gene denotes angiotensin converting enzyme 2 Gene:59272
47 1675-1722 Species denotes severe acute respiratory syndrome coronavirus 2 Tax:2697049
48 1724-1734 Species denotes SARS-CoV-2 Tax:2697049
49 1786-1796 Species denotes SARS-COV-2 Tax:2697049
50 1859-1881 Species denotes bat coronavirus RaTG13 Tax:2709072
51 1920-1930 Species denotes SARS-COV-2 Tax:2697049
52 2310-2315 Chemical denotes lipid MESH:D008055
53 1624-1648 Disease denotes coronavirus disease 2019 MESH:C000657245
54 1650-1658 Disease denotes COVID-19 MESH:C000657245
55 2050-2059 Disease denotes mortality MESH:D003643
56 2069-2077 Disease denotes COVID-19 MESH:C000657245
57 2152-2157 Disease denotes death MESH:D003643
58 2217-2222 Disease denotes edema MESH:D004487
59 2335-2343 Disease denotes COVID-19 MESH:C000657245
75 2420-2428 Species denotes patients Tax:9606
76 2690-2698 Species denotes patients Tax:9606
77 2812-2821 Species denotes SARS-CoV2 Tax:2697049
78 2856-2866 Species denotes SARS-CoV-2 Tax:2697049
79 2929-2937 Species denotes patients Tax:9606
80 3093-3101 Species denotes patients Tax:9606
81 2743-2749 Chemical denotes lipids MESH:D008055
82 3168-3173 Chemical denotes lipid MESH:D008055
83 2411-2419 Disease denotes COVID-19 MESH:C000657245
84 2520-2539 Disease denotes infectious diseases MESH:D003141
85 2822-2831 Disease denotes infection MESH:D007239
86 2878-2886 Disease denotes COVID-19 MESH:C000657245
87 3107-3144 Disease denotes chronic obstructive pulmonary disease MESH:D029424
88 3146-3150 Disease denotes COPD MESH:D029424
89 3267-3275 Disease denotes COVID-19 MESH:C000657245
100 5319-5338 Chemical denotes Lopinavir/ritonavir MESH:C558899
101 4903-4911 Disease denotes diabetes MESH:D003920
102 4937-4949 Disease denotes Hypertension MESH:D006973
103 4979-5001 Disease denotes Cardiovascular disease MESH:D002318
104 5030-5045 Disease denotes Kidney diseases MESH:D007674
105 5074-5089 Disease denotes symptoms  Fever MESH:D051271
106 5119-5124 Disease denotes Cough MESH:D003371
107 5154-5161 Disease denotes Fatigue MESH:D005221
108 5191-5210 Disease denotes Shortness of breath MESH:D004417
109 5238-5246 Disease denotes Diarrhea MESH:D003967
112 4696-4704 Species denotes patients Tax:9606
113 4687-4695 Disease denotes COVID-19 MESH:C000657245
115 5605-5612 Species denotes patient Tax:9606
136 3658-3666 Species denotes patients Tax:9606
137 3865-3873 Species denotes patients Tax:9606
138 4010-4018 Species denotes patients Tax:9606
139 4160-4168 Species denotes Patients Tax:9606
140 4573-4581 Species denotes patients Tax:9606
141 4624-4632 Species denotes patients Tax:9606
142 4268-4275 Chemical denotes arbidol MESH:C086979
143 4277-4286 Chemical denotes lopinavir MESH:D061466
144 4291-4300 Chemical denotes ribonavir
145 4485-4491 Chemical denotes oxygen MESH:D010100
146 3753-3761 Disease denotes diabetes MESH:D003920
147 3763-3775 Disease denotes hypertension MESH:D006973
148 3777-3801 Disease denotes cardiovascular disorders MESH:D002318
149 3803-3817 Disease denotes hyperlipidemia MESH:D006949
150 3822-3837 Disease denotes kidney diseases MESH:D007674
151 3880-3885 Disease denotes fever MESH:D005334
152 3893-3898 Disease denotes cough MESH:D003371
153 3906-3913 Disease denotes fatigue MESH:D005221
154 3921-3940 Disease denotes shortness of breath MESH:D004417
155 3951-3959 Disease denotes diarrhea MESH:D003967
162 6997-7001 Gene denotes IL-6 Gene:3569
163 7220-7223 Gene denotes CD4 Gene:920
164 7307-7310 Gene denotes CD8 Gene:925
165 7391-7394 Gene denotes CD4 Gene:920
166 7396-7399 Gene denotes CD8 Gene:925
167 7070-7073 Gene denotes CRP Gene:1401
170 6851-6859 Species denotes patients Tax:9606
171 6842-6850 Disease denotes COVID-19 MESH:C000657245
186 5713-5731 Gene denotes C-reactive protein Gene:1401
187 5733-5736 Gene denotes CRP Gene:1401
188 5793-5806 Gene denotes interleukin-6 Gene:3569
189 5808-5812 Gene denotes IL-6 Gene:3569
190 5889-5892 Gene denotes CD8 Gene:925
191 5989-5997 Species denotes patients Tax:9606
192 6019-6027 Species denotes patients Tax:9606
193 6076-6084 Species denotes patients Tax:9606
194 6686-6694 Species denotes patients Tax:9606
195 6199-6208 Disease denotes infection MESH:D007239
196 6454-6463 Disease denotes infection MESH:D007239
197 6527-6536 Disease denotes infection MESH:D007239
198 6762-6773 Disease denotes lymphopenia MESH:D008231
199 6780-6785 Disease denotes death MESH:D003643
210 9158-9166 Species denotes patients Tax:9606
211 9307-9314 Species denotes patient Tax:9606
212 9841-9849 Species denotes patients Tax:9606
213 9139-9141 Chemical denotes TC
214 9272-9274 Chemical denotes TC
215 9992-9994 Chemical denotes TC
216 9149-9157 Disease denotes COVID-19 MESH:C000657245
217 9284-9293 Disease denotes infection MESH:D007239
218 9557-9566 Disease denotes infection MESH:D007239
219 9819-9828 Disease denotes infection MESH:D007239
234 7854-7862 Species denotes patients Tax:9606
235 7892-7902 Species denotes SARS-CoV-2 Tax:2697049
236 8060-8068 Species denotes patients Tax:9606
237 8361-8369 Species denotes patients Tax:9606
238 7822-7827 Chemical denotes lipid MESH:D008055
239 8857-8868 Chemical denotes cholesterol MESH:D002784
240 8870-8872 Chemical denotes TC
241 7880-7888 Disease denotes infected MESH:D007239
242 8158-8167 Disease denotes infection MESH:D007239
243 8173-8182 Disease denotes infection MESH:D007239
244 8348-8357 Disease denotes infection MESH:D007239
245 8591-8600 Disease denotes infection MESH:D007239
246 8606-8615 Disease denotes infection MESH:D007239
247 8944-8953 Disease denotes infection MESH:D007239
264 10097-10105 Species denotes patients Tax:9606
265 10473-10480 Species denotes patient Tax:9606
266 10646-10654 Species denotes patients Tax:9606
267 10753-10761 Species denotes patients Tax:9606
268 10080-10082 Chemical denotes TC
269 10576-10578 Chemical denotes TC
270 10600-10602 Chemical denotes TC
271 11152-11154 Chemical denotes TC
272 10164-10169 Disease denotes death MESH:D003643
273 10297-10302 Disease denotes death MESH:D003643
274 10509-10514 Disease denotes death MESH:D003643
275 10637-10645 Disease denotes COVID-19 MESH:C000657245
276 10656-10660 Disease denotes COPD MESH:D029424
277 10744-10752 Disease denotes COVID-19 MESH:C000657245
278 10775-10791 Disease denotes viral infections MESH:D001102
279 11024-11033 Disease denotes mortality MESH:D003643
285 11313-11321 Species denotes patients Tax:9606
286 11600-11608 Species denotes patients Tax:9606
287 11288-11300 Disease denotes dyslipidemia MESH:D050171
288 11304-11312 Disease denotes COVID-19 MESH:C000657245
289 11423-11447 Disease denotes mortality of the disease MESH:D003643
313 11726-11734 Species denotes patients Tax:9606
314 12250-12258 Species denotes patients Tax:9606
315 12679-12687 Species denotes patients Tax:9606
316 12178-12185 Species denotes patient Tax:9606
317 11701-11706 Chemical denotes lipid MESH:D008055
318 11889-11894 Chemical denotes lipid MESH:D008055
319 12017-12022 Chemical denotes lipid MESH:D008055
320 12064-12087 Chemical denotes reactive oxygen species MESH:D017382
321 12483-12494 Chemical denotes cholesterol MESH:D002784
322 12802-12808 Chemical denotes lipids MESH:D008055
323 11717-11725 Disease denotes COVID-19 MESH:C000657245
324 11764-11776 Disease denotes liver injury MESH:D017093
325 11957-11972 Disease denotes viral infection MESH:D001102
326 12241-12249 Disease denotes COVID-19 MESH:C000657245
327 12327-12339 Disease denotes inflammation MESH:D007249
328 12398-12406 Disease denotes COVID-19 MESH:C000657245
329 12510-12522 Disease denotes inflammation MESH:D007249
330 12842-12850 Disease denotes COVID-19 MESH:C000657245
331 12923-12931 Disease denotes COVID-19 MESH:C000657245
332 12965-12977 Disease denotes dyslipidemia MESH:D050171
333 13033-13041 Disease denotes COVID-19 MESH:C000657245
334 13189-13197 Disease denotes COVID-19 MESH:C000657245
335 13262-13271 Disease denotes mortality MESH:D003643

2_test

Id Subject Object Predicate Lexical cue
32320740-32009228-69344053 1782-1783 32009228 denotes 1
32320740-32007145-69344054 1884-1885 32007145 denotes 2
32320740-32007145-69344055 2030-2031 32007145 denotes 2
32320740-31994742-69344056 2161-2162 31994742 denotes 7
32320740-32009228-69344057 4156-4157 32009228 denotes 1
32320740-27245605-69344058 12127-12129 27245605 denotes 11
32320740-25267014-69344059 12133-12135 25267014 denotes 12
32320740-23522788-69344060 12139-12141 23522788 denotes 13
32320740-4642731-69344061 12554-12556 4642731 denotes 14
32320740-12065357-69344062 12557-12559 12065357 denotes 15