PMC:7164862 / 63-842
Annnotations
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
17 | 93-138 | Species | denotes | severe acute respiratory syndrome coronavirus | Tax:694009 |
18 | 140-148 | Species | denotes | SARS-CoV | Tax:694009 |
19 | 251-262 | Species | denotes | coronavirus | Tax:11118 |
20 | 618-624 | Species | denotes | humans | Tax:9606 |
21 | 33-44 | Chemical | denotes | chloroquine | MESH:D002738 |
22 | 207-218 | Chemical | denotes | chloroquine | MESH:D002738 |
23 | 286-297 | Chemical | denotes | chloroquine | MESH:D002738 |
24 | 480-491 | Chemical | denotes | chloroquine | MESH:D002738 |
25 | 712-723 | Chemical | denotes | chloroquine | MESH:D002738 |
26 | 549-558 | Disease | denotes | infection | MESH:D007239 |
27 | 736-758 | Disease | denotes | coronavirus infections | MESH:D018352 |
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T1 | 306-319 | Body_part | denotes | immune system | http://purl.org/sig/ont/fma/fma9825 |
LitCovid-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T1 | 306-319 | Body_part | denotes | immune system | http://purl.obolibrary.org/obo/UBERON_0002405 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T2 | 93-126 | Disease | denotes | severe acute respiratory syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
T3 | 140-148 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T4 | 465-469 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T5 | 549-558 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T6 | 748-758 | Disease | denotes | infections | http://purl.obolibrary.org/obo/MONDO_0005550 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 74-81 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
T2 | 306-319 | http://purl.obolibrary.org/obo/UBERON_0002405 | denotes | immune system |
T3 | 320-328 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
T4 | 444-448 | http://purl.obolibrary.org/obo/CLO_0001757 | denotes | 1 At |
T5 | 509-510 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T6 | 618-624 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | humans |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T3 | 33-44 | Chemical | denotes | chloroquine | http://purl.obolibrary.org/obo/CHEBI_3638 |
T4 | 207-218 | Chemical | denotes | chloroquine | http://purl.obolibrary.org/obo/CHEBI_3638 |
T5 | 286-297 | Chemical | denotes | chloroquine | http://purl.obolibrary.org/obo/CHEBI_3638 |
T6 | 480-491 | Chemical | denotes | chloroquine | http://purl.obolibrary.org/obo/CHEBI_3638 |
T7 | 511-515 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
T8 | 712-723 | Chemical | denotes | chloroquine | http://purl.obolibrary.org/obo/CHEBI_3638 |
LitCovid-PD-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 345-371 | http://purl.obolibrary.org/obo/GO_0050728 | denotes | anti-inflammatory response |
T2 | 350-371 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammatory response |
T3 | 422-443 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammatory response |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T2 | 0-275 | Sentence | denotes | In-vitro studies have shown that chloroquine is effective against several viruses, including severe acute respiratory syndrome coronavirus (SARS-CoV).1 Multiple mechanisms of action have been identified for chloroquine that disrupt the early stage of coronavirus replication. |
T3 | 276-779 | Sentence | denotes | Moreover, chloroquine affects immune system activity by mediating an anti-inflammatory response, which might reduce damage due to the exaggerated inflammatory response.1 At the time of the SARS epidemic, chloroquine was suggested as a drug that could be used to treat this infection.2 However, randomised, double-blind, controlled studies in humans to evaluate its efficacy for this use were not done, and the true clinical efficacy of chloroquine in treating coronavirus infections was not established. |
LitCovid-PMC-OGER-BB
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T4 | 33-44 | CHEBI:3638;DG_10;CHEBI:3638 | denotes | chloroquine |
T5 | 74-81 | NCBITaxon:10239 | denotes | viruses |
T6 | 93-105 | SP_10 | denotes | severe acute |
T7 | 106-117 | SP_10;UBERON:0001004 | denotes | respiratory |
T8 | 118-138 | SP_10 | denotes | syndrome coronavirus |
T9 | 140-148 | SP_10 | denotes | SARS-CoV |
T10 | 207-218 | CHEBI:3638;DG_10;CHEBI:3638 | denotes | chloroquine |
T11 | 251-262 | NCBITaxon:11118 | denotes | coronavirus |
T12 | 263-274 | GO:0006260 | denotes | replication |
T13 | 286-297 | CHEBI:3638;DG_10;CHEBI:3638 | denotes | chloroquine |
T14 | 306-319 | UBERON:0002405 | denotes | immune system |
T15 | 465-469 | SP_10 | denotes | SARS |
T16 | 480-491 | CHEBI:3638;DG_10;CHEBI:3638 | denotes | chloroquine |
T17 | 511-515 | CHEBI:23888;CHEBI:23888 | denotes | drug |
T18 | 618-624 | NCBITaxon:9606 | denotes | humans |
T19 | 712-723 | CHEBI:3638;DG_10;CHEBI:3638 | denotes | chloroquine |
T20 | 736-747 | NCBITaxon:11118 | denotes | coronavirus |
T98454 | 33-44 | CHEBI:3638;DG_10;CHEBI:3638 | denotes | chloroquine |
T25476 | 74-81 | NCBITaxon:10239 | denotes | viruses |
T35585 | 93-105 | SP_10 | denotes | severe acute |
T99185 | 106-117 | SP_10;UBERON:0001004 | denotes | respiratory |
T79442 | 118-138 | SP_10 | denotes | syndrome coronavirus |
T65667 | 140-148 | SP_10 | denotes | SARS-CoV |
T1801 | 207-218 | CHEBI:3638;DG_10;CHEBI:3638 | denotes | chloroquine |
T88121 | 251-262 | NCBITaxon:11118 | denotes | coronavirus |
T96813 | 263-274 | GO:0006260 | denotes | replication |
T9936 | 286-297 | CHEBI:3638;DG_10;CHEBI:3638 | denotes | chloroquine |
T13615 | 306-319 | UBERON:0002405 | denotes | immune system |
T96197 | 465-469 | SP_10 | denotes | SARS |
T17697 | 480-491 | CHEBI:3638;DG_10;CHEBI:3638 | denotes | chloroquine |
T13009 | 511-515 | CHEBI:23888;CHEBI:23888 | denotes | drug |
T56976 | 618-624 | NCBITaxon:9606 | denotes | humans |
T51915 | 712-723 | CHEBI:3638;DG_10;CHEBI:3638 | denotes | chloroquine |
T97546 | 736-747 | NCBITaxon:11118 | denotes | coronavirus |