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PMC:7161517 / 26718-27422 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T149 168-175 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T150 204-211 Body_part denotes cytosol http://purl.org/sig/ont/fma/fma66836
T151 219-226 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T152 336-342 Body_part denotes serine http://purl.org/sig/ont/fma/fma82764
T153 561-571 Body_part denotes calmodulin http://purl.org/sig/ont/fma/fma62343

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T136 41-49 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T137 61-108 Disease denotes Severe acute respiratory syndrome coronavirus 2 http://purl.obolibrary.org/obo/MONDO_0100096
T138 110-118 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T139 282-287 Disease denotes tumor http://purl.obolibrary.org/obo/MONDO_0005070
T140 514-522 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T240 393-395 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T241 400-402 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T242 400-402 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T243 412-414 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T244 412-414 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T245 422-429 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T246 447-455 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T295 168-175 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T296 219-226 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T297 237-241 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T298 336-342 Chemical denotes serine http://purl.obolibrary.org/obo/CHEBI_17822
T299 400-402 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T300 412-414 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T301 422-429 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T302 572-582 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T67 288-296 http://purl.obolibrary.org/obo/GO_0070265 denotes necrosis
T68 288-296 http://purl.obolibrary.org/obo/GO_0019835 denotes necrosis
T69 288-296 http://purl.obolibrary.org/obo/GO_0008219 denotes necrosis
T70 288-296 http://purl.obolibrary.org/obo/GO_0001906 denotes necrosis
T71 377-386 http://purl.obolibrary.org/obo/GO_0009058 denotes formation
T72 494-505 http://purl.obolibrary.org/obo/GO_0006897 denotes endocytosis
T73 594-613 http://purl.obolibrary.org/obo/GO_0006509 denotes ectodomain cleavage

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T164 0-60 Sentence denotes Figure 2 Proposed Mechanism of Entry for SARS-CoV-2 Via ACE2
T165 61-176 Sentence denotes Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) binds to the catalytic site of ACE2 via its S protein.
T166 177-411 Sentence denotes To gain access to the host cytosol, the S protein undergoes acid dependent proteolytic cleavage by ACE2, tumor necrosis factor (TNF)-α, transmembrane protease serine 2 (TMPRRS2), which results in the formation of an S1 and S2 subunit.
T167 412-525 Sentence denotes S2 fusion peptide inserts into the membrane, which allows for clatherin-dependent endocytosis of ACE2-SARS-CoV-2.
T168 526-622 Sentence denotes Viral binding stimulates TNF-α and calmodulin inhibitors to promote ectodomain cleavage of ACE2.
T169 623-704 Sentence denotes ADAM 17 = disintegrin and metalloprotease 17; other abbreviations as in Figure 1.

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T41 282-287 Phenotype denotes tumor http://purl.obolibrary.org/obo/HP_0002664

LitCovid-PMC-OGER-BB

Id Subject Object Predicate Lexical cue
T854 41-51 SP_7 denotes SARS-CoV-2
T855 56-67 G_3;PG_10;SP_7 denotes ACE2 Severe
T856 68-73 SP_7 denotes acute
T857 74-85 SP_7;GO:0045333;UBERON:0001004 denotes respiratory
T858 86-108 SP_7 denotes syndrome coronavirus 2
T859 110-120 SP_7 denotes SARS-CoV-2
T860 153-157 G_3;PG_10;PR:000003622 denotes ACE2
T861 166-175 PG_1 denotes S protein
T862 199-211 GO:0044164 denotes host cytosol
T863 217-226 PG_1 denotes S protein
T864 237-241 CHEBI:37527;CHEBI:37527 denotes acid
T865 242-251 GO:0010498 denotes dependent
T866 252-263 GO:0006508 denotes proteolytic
T867 264-272 MOP:0000780 denotes cleavage
T868 276-280 G_3;PG_10;PR:000003622 denotes ACE2
T869 305-308 PR:000000134 denotes TNF
T870 313-326 GO:0016020;PG_8 denotes transmembrane
T871 327-344 PG_8 denotes protease serine 2
T872 430-437 SO:0000667 denotes inserts
T873 447-455 GO:0016020 denotes membrane
T874 474-493 GO:0017156 denotes clatherin-dependent
T875 494-505 GO:0006897 denotes endocytosis
T876 509-513 G_3;PG_10;PR:000003622 denotes ACE2
T877 514-524 SP_7 denotes SARS-CoV-2
T878 551-556 PR:000000134 denotes TNF-α
T879 561-571 PR:000004978 denotes calmodulin
T880 572-582 CHEBI:35222;CHEBI:35222 denotes inhibitors
T881 605-613 MOP:0000780 denotes cleavage
T882 617-621 PR:000003622;G_3;PG_10 denotes ACE2
T883 623-630 PR:000001279 denotes ADAM 17
T886 61-73 SP_7 denotes Severe acute
T884 41-51 SP_7 denotes SARS-CoV-2
T885 56-60 G_3;PG_10;PR:000003622 denotes ACE2
T887 74-85 SP_7;UBERON:0001004;GO:0045333 denotes respiratory
T888 86-108 SP_7 denotes syndrome coronavirus 2
T889 110-120 SP_7 denotes SARS-CoV-2
T890 153-157 G_3;PG_10;PR:000003622 denotes ACE2
T891 166-175 PG_1 denotes S protein
T892 199-211 GO:0044164 denotes host cytosol
T893 217-226 PG_1 denotes S protein
T894 237-241 CHEBI:37527;CHEBI:37527 denotes acid
T895 242-251 GO:0010498 denotes dependent
T896 252-263 GO:0006508 denotes proteolytic
T897 264-272 MOP:0000780 denotes cleavage
T898 276-280 G_3;PG_10;PR:000003622 denotes ACE2
T899 305-308 PR:000000134 denotes TNF
T900 313-326 GO:0016020;PG_8 denotes transmembrane
T901 327-344 PG_8 denotes protease serine 2
T902 430-437 SO:0000667 denotes inserts
T903 447-455 GO:0016020 denotes membrane
T904 474-493 GO:0017156 denotes clatherin-dependent
T905 494-505 GO:0006897 denotes endocytosis
T906 509-513 G_3;PG_10;PR:000003622 denotes ACE2
T907 514-524 SP_7 denotes SARS-CoV-2
T908 551-556 PR:000000134 denotes TNF-α
T909 561-571 PR:000004978 denotes calmodulin
T910 572-582 CHEBI:35222;CHEBI:35222 denotes inhibitors
T911 605-613 MOP:0000780 denotes cleavage
T912 617-621 PR:000003622;G_3;PG_10 denotes ACE2
T913 623-630 PR:000001279 denotes ADAM 17

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
1125 41-51 Species denotes SARS-CoV-2 Tax:2697049
1141 153-157 Gene denotes ACE2 Gene:59272
1142 276-280 Gene denotes ACE2 Gene:59272
1143 282-311 Gene denotes tumor necrosis factor (TNF)-α Gene:7124
1144 313-344 Gene denotes transmembrane protease serine 2 Gene:7113
1145 509-513 Gene denotes ACE2 Gene:59272
1146 551-556 Gene denotes TNF-α Gene:7124
1147 561-571 Gene denotes calmodulin Gene:801
1148 617-621 Gene denotes ACE2 Gene:59272
1149 623-630 Gene denotes ADAM 17 Gene:6868
1150 217-218 Gene denotes S Gene:43740568
1151 166-167 Gene denotes S Gene:43740568
1152 61-108 Species denotes Severe acute respiratory syndrome coronavirus 2 Tax:2697049
1153 110-120 Species denotes SARS-CoV-2 Tax:2697049
1154 514-524 Species denotes SARS-CoV-2 Tax:2697049
1155 474-483 Chemical denotes clatherin