PMC:7161517 / 19119-19523 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7161517","sourcedb":"PMC","sourceid":"7161517","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7161517","text":"ase neprilysin (17), although with less favorable kinetics at baseline. Thus, it can be assumed ACE inhibitors disrupt the balance between catalytically active ACE and ACE2, resulting in favored activation of the ACE2/Ang1-7/Mas axis.\nOverall, because of the demonstrated anti-inflammatory, antifibrotic, and antithrombotic effects associated with the ACE2/Ang1-7/Mas axis, upregulation could serve as a ","tracks":[{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T114","span":{"begin":229,"end":233},"obj":"Body_part"},{"id":"T115","span":{"begin":368,"end":372},"obj":"Body_part"}],"attributes":[{"id":"A114","pred":"fma_id","subj":"T114","obj":"http://purl.org/sig/ont/fma/fma12520"},{"id":"A115","pred":"fma_id","subj":"T115","obj":"http://purl.org/sig/ont/fma/fma12520"},{"subj":"T114","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T115","pred":"source","obj":"LitCovid-PD-FMA-UBERON"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T184","span":{"begin":4,"end":14},"obj":"http://purl.obolibrary.org/obo/PR_000001898"},{"id":"T185","span":{"begin":153,"end":159},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T186","span":{"begin":195,"end":205},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T187","span":{"begin":402,"end":403},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"attributes":[{"subj":"T184","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T185","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T186","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T187","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T250","span":{"begin":96,"end":110},"obj":"Chemical"},{"id":"T251","span":{"begin":100,"end":110},"obj":"Chemical"}],"attributes":[{"id":"A250","pred":"chebi_id","subj":"T250","obj":"http://purl.obolibrary.org/obo/CHEBI_35457"},{"id":"A251","pred":"chebi_id","subj":"T251","obj":"http://purl.obolibrary.org/obo/CHEBI_35222"},{"subj":"T250","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T251","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T121","span":{"begin":72,"end":234},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T121","pred":"source","obj":"LitCovid-sentences"}]},{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T707","span":{"begin":4,"end":14},"obj":"PR:000001898"},{"id":"T708","span":{"begin":100,"end":110},"obj":"CHEBI:35222;CHEBI:35222"},{"id":"T709","span":{"begin":168,"end":172},"obj":"G_3;PG_10;PR:000003622"},{"id":"T710","span":{"begin":213,"end":217},"obj":"G_3;PG_10;PR:000003622"},{"id":"T711","span":{"begin":218,"end":222},"obj":"PR:000036013"},{"id":"T712","span":{"begin":309,"end":323},"obj":"GO:0007596"},{"id":"T713","span":{"begin":352,"end":356},"obj":"G_3;PG_10;PR:000003622"},{"id":"T714","span":{"begin":357,"end":361},"obj":"PR:000036013"},{"id":"T715","span":{"begin":364,"end":367},"obj":"PR:000001563"},{"id":"T84387","span":{"begin":34,"end":52},"obj":"UBERON:0002012"},{"id":"T17302","span":{"begin":75,"end":80},"obj":"NCBITaxon:39107"},{"id":"T83070","span":{"begin":109,"end":118},"obj":"GO:0065007"},{"id":"T26990","span":{"begin":189,"end":195},"obj":"NCBITaxon:9606"},{"id":"T44915","span":{"begin":268,"end":273},"obj":"SP_6;NCBITaxon:9606;PG_10"},{"id":"T17920","span":{"begin":274,"end":305},"obj":"PG_10;PR:000003622"}],"attributes":[{"subj":"T707","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T708","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T709","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T710","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T711","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T712","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T713","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T714","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T715","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T84387","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T17302","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T83070","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T26990","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T44915","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T17920","pred":"source","obj":"LitCovid-PMC-OGER-BB"}]},{"project":"LitCovid-PubTator","denotations":[{"id":"823","span":{"begin":4,"end":14},"obj":"Gene"},{"id":"824","span":{"begin":96,"end":99},"obj":"Gene"},{"id":"825","span":{"begin":160,"end":163},"obj":"Gene"},{"id":"826","span":{"begin":168,"end":172},"obj":"Gene"},{"id":"827","span":{"begin":213,"end":217},"obj":"Gene"},{"id":"828","span":{"begin":218,"end":224},"obj":"Gene"},{"id":"840","span":{"begin":352,"end":356},"obj":"Gene"},{"id":"841","span":{"begin":357,"end":363},"obj":"Gene"}],"attributes":[{"id":"A823","pred":"tao:has_database_id","subj":"823","obj":"Gene:4311"},{"id":"A824","pred":"tao:has_database_id","subj":"824","obj":"Gene:1636"},{"id":"A825","pred":"tao:has_database_id","subj":"825","obj":"Gene:1636"},{"id":"A826","pred":"tao:has_database_id","subj":"826","obj":"Gene:59272"},{"id":"A827","pred":"tao:has_database_id","subj":"827","obj":"Gene:59272"},{"id":"A828","pred":"tao:has_database_id","subj":"828","obj":"Gene:284"},{"id":"A840","pred":"tao:has_database_id","subj":"840","obj":"Gene:59272"},{"id":"A841","pred":"tao:has_database_id","subj":"841","obj":"Gene:284"},{"subj":"823","pred":"source","obj":"LitCovid-PubTator"},{"subj":"824","pred":"source","obj":"LitCovid-PubTator"},{"subj":"825","pred":"source","obj":"LitCovid-PubTator"},{"subj":"826","pred":"source","obj":"LitCovid-PubTator"},{"subj":"827","pred":"source","obj":"LitCovid-PubTator"},{"subj":"828","pred":"source","obj":"LitCovid-PubTator"},{"subj":"840","pred":"source","obj":"LitCovid-PubTator"},{"subj":"841","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"2_test","denotations":[{"id":"32305401-15283675-55252970","span":{"begin":16,"end":18},"obj":"15283675"}],"attributes":[{"subj":"32305401-15283675-55252970","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PD-FMA-UBERON","color":"#ec93c1","default":true},{"id":"LitCovid-PD-CLO","color":"#93dbec"},{"id":"LitCovid-PD-CHEBI","color":"#ece393"},{"id":"LitCovid-sentences","color":"#c993ec"},{"id":"LitCovid-PMC-OGER-BB","color":"#93ecaf"},{"id":"LitCovid-PubTator","color":"#ec9593"},{"id":"2_test","color":"#93aaec"}]}]}}