PMC:7161517 / 18909-19190 JSONTXT

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T184","span":{"begin":214,"end":224},"obj":"http://purl.obolibrary.org/obo/PR_000001898"}],"text":"Although Ang II is the predominant substrate, ACE2 can also convert Ang I into Ang 1-9, which, in turn, could be converted to Ang 1-7 via ACE; Ang I can be directly converted into Ang 1-7 via zinc metallopeptidase neprilysin (17), although with less favorable kinetics at baseline."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T247","span":{"begin":13,"end":15},"obj":"Chemical"},{"id":"T248","span":{"begin":192,"end":196},"obj":"Chemical"}],"attributes":[{"id":"A247","pred":"chebi_id","subj":"T247","obj":"http://purl.obolibrary.org/obo/CHEBI_74067"},{"id":"A248","pred":"chebi_id","subj":"T248","obj":"http://purl.obolibrary.org/obo/CHEBI_27363"},{"id":"A249","pred":"chebi_id","subj":"T248","obj":"http://purl.obolibrary.org/obo/CHEBI_30185"}],"text":"Although Ang II is the predominant substrate, ACE2 can also convert Ang I into Ang 1-9, which, in turn, could be converted to Ang 1-7 via ACE; Ang I can be directly converted into Ang 1-7 via zinc metallopeptidase neprilysin (17), although with less favorable kinetics at baseline."}

{"project":"LitCovid-sentences","denotations":[{"id":"T120","span":{"begin":0,"end":281},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Although Ang II is the predominant substrate, ACE2 can also convert Ang I into Ang 1-9, which, in turn, could be converted to Ang 1-7 via ACE; Ang I can be directly converted into Ang 1-7 via zinc metallopeptidase neprilysin (17), although with less favorable kinetics at baseline."}

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T701","span":{"begin":9,"end":15},"obj":"PR:000036009"},{"id":"T702","span":{"begin":46,"end":50},"obj":"PR:000003622;G_3;PG_10"},{"id":"T703","span":{"begin":68,"end":73},"obj":"PR:000036008"},{"id":"T704","span":{"begin":79,"end":84},"obj":"PR:000036012"},{"id":"T705","span":{"begin":143,"end":148},"obj":"PR:000036008"},{"id":"T706","span":{"begin":180,"end":185},"obj":"PR:000036013"},{"id":"T707","span":{"begin":214,"end":224},"obj":"PR:000001898"},{"id":"T27522","span":{"begin":15,"end":21},"obj":"PR:000036009"},{"id":"T18328","span":{"begin":22,"end":25},"obj":"PR:000001251"},{"id":"T97445","span":{"begin":67,"end":71},"obj":"G_3;PG_10;PR:000003622"},{"id":"T95349","span":{"begin":72,"end":76},"obj":"PR:000036013"},{"id":"T57032","span":{"begin":195,"end":207},"obj":"UBERON:0001004"},{"id":"T84387","span":{"begin":244,"end":262},"obj":"UBERON:0002012"}],"text":"Although Ang II is the predominant substrate, ACE2 can also convert Ang I into Ang 1-9, which, in turn, could be converted to Ang 1-7 via ACE; Ang I can be directly converted into Ang 1-7 via zinc metallopeptidase neprilysin (17), although with less favorable kinetics at baseline."}

{"project":"LitCovid-PubTator","denotations":[{"id":"816","span":{"begin":9,"end":15},"obj":"Gene"},{"id":"817","span":{"begin":46,"end":50},"obj":"Gene"},{"id":"818","span":{"begin":79,"end":86},"obj":"Gene"},{"id":"819","span":{"begin":126,"end":133},"obj":"Gene"},{"id":"820","span":{"begin":138,"end":141},"obj":"Gene"},{"id":"821","span":{"begin":143,"end":148},"obj":"Gene"},{"id":"822","span":{"begin":180,"end":187},"obj":"Gene"},{"id":"823","span":{"begin":214,"end":224},"obj":"Gene"},{"id":"830","span":{"begin":68,"end":73},"obj":"Gene"}],"attributes":[{"id":"A816","pred":"tao:has_database_id","subj":"816","obj":"Gene:183"},{"id":"A817","pred":"tao:has_database_id","subj":"817","obj":"Gene:59272"},{"id":"A818","pred":"tao:has_database_id","subj":"818","obj":"Gene:284"},{"id":"A819","pred":"tao:has_database_id","subj":"819","obj":"Gene:284"},{"id":"A820","pred":"tao:has_database_id","subj":"820","obj":"Gene:1636"},{"id":"A821","pred":"tao:has_database_id","subj":"821","obj":"Gene:183"},{"id":"A822","pred":"tao:has_database_id","subj":"822","obj":"Gene:284"},{"id":"A823","pred":"tao:has_database_id","subj":"823","obj":"Gene:4311"},{"id":"A830","pred":"tao:has_database_id","subj":"830","obj":"Gene:183"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Although Ang II is the predominant substrate, ACE2 can also convert Ang I into Ang 1-9, which, in turn, could be converted to Ang 1-7 via ACE; Ang I can be directly converted into Ang 1-7 via zinc metallopeptidase neprilysin (17), although with less favorable kinetics at baseline."}

{"project":"2_test","denotations":[{"id":"32305401-15283675-55252970","span":{"begin":226,"end":228},"obj":"15283675"}],"text":"Although Ang II is the predominant substrate, ACE2 can also convert Ang I into Ang 1-9, which, in turn, could be converted to Ang 1-7 via ACE; Ang I can be directly converted into Ang 1-7 via zinc metallopeptidase neprilysin (17), although with less favorable kinetics at baseline."}