PMC:7161517 / 17295-17576 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T105","span":{"begin":50,"end":58},"obj":"Body_part"}],"attributes":[{"id":"A105","pred":"fma_id","subj":"T105","obj":"http://purl.org/sig/ont/fma/fma63891"}],"text":"ulted in improved cardiac function and alleviated collagen disposition (49). These experiments suggested that both ACE inhibitors and ARBs variably upregulated ACE2 expression (49). ARBs inhibited binding of Ang II to the AT1 receptor, which permitted circulating Ang II to be shun"}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T73","span":{"begin":222,"end":225},"obj":"Disease"}],"attributes":[{"id":"A73","pred":"mondo_id","subj":"T73","obj":"http://purl.obolibrary.org/obo/MONDO_0008840"}],"text":"ulted in improved cardiac function and alleviated collagen disposition (49). These experiments suggested that both ACE inhibitors and ARBs variably upregulated ACE2 expression (49). ARBs inhibited binding of Ang II to the AT1 receptor, which permitted circulating Ang II to be shun"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T175","span":{"begin":50,"end":58},"obj":"http://purl.obolibrary.org/obo/CHEBI_3815"}],"text":"ulted in improved cardiac function and alleviated collagen disposition (49). These experiments suggested that both ACE inhibitors and ARBs variably upregulated ACE2 expression (49). ARBs inhibited binding of Ang II to the AT1 receptor, which permitted circulating Ang II to be shun"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T221","span":{"begin":115,"end":129},"obj":"Chemical"},{"id":"T222","span":{"begin":119,"end":129},"obj":"Chemical"},{"id":"T223","span":{"begin":212,"end":214},"obj":"Chemical"},{"id":"T224","span":{"begin":268,"end":270},"obj":"Chemical"}],"attributes":[{"id":"A221","pred":"chebi_id","subj":"T221","obj":"http://purl.obolibrary.org/obo/CHEBI_35457"},{"id":"A222","pred":"chebi_id","subj":"T222","obj":"http://purl.obolibrary.org/obo/CHEBI_35222"},{"id":"A223","pred":"chebi_id","subj":"T223","obj":"http://purl.obolibrary.org/obo/CHEBI_74067"},{"id":"A224","pred":"chebi_id","subj":"T224","obj":"http://purl.obolibrary.org/obo/CHEBI_74067"}],"text":"ulted in improved cardiac function and alleviated collagen disposition (49). These experiments suggested that both ACE inhibitors and ARBs variably upregulated ACE2 expression (49). ARBs inhibited binding of Ang II to the AT1 receptor, which permitted circulating Ang II to be shun"}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T57","span":{"begin":187,"end":204},"obj":"http://purl.obolibrary.org/obo/GO_0051100"}],"text":"ulted in improved cardiac function and alleviated collagen disposition (49). These experiments suggested that both ACE inhibitors and ARBs variably upregulated ACE2 expression (49). ARBs inhibited binding of Ang II to the AT1 receptor, which permitted circulating Ang II to be shun"}

{"project":"LitCovid-sentences","denotations":[{"id":"T110","span":{"begin":77,"end":181},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"ulted in improved cardiac function and alleviated collagen disposition (49). These experiments suggested that both ACE inhibitors and ARBs variably upregulated ACE2 expression (49). ARBs inhibited binding of Ang II to the AT1 receptor, which permitted circulating Ang II to be shun"}

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T647","span":{"begin":18,"end":25},"obj":"UBERON:0000948"},{"id":"T648","span":{"begin":119,"end":129},"obj":"CHEBI:35222;CHEBI:35222"},{"id":"T649","span":{"begin":160,"end":164},"obj":"G_3;PG_10;PR:000003622"},{"id":"T650","span":{"begin":165,"end":175},"obj":"GO:0010467"},{"id":"T651","span":{"begin":208,"end":211},"obj":"CHEBI:37886;CHEBI:37886;PR:000036009"},{"id":"T652","span":{"begin":212,"end":214},"obj":"PR:000036009"},{"id":"T653","span":{"begin":264,"end":270},"obj":"PR:000036009"},{"id":"T27622","span":{"begin":24,"end":34},"obj":"CHEBI:35222;CHEBI:35222"},{"id":"T45254","span":{"begin":61,"end":64},"obj":"PR:000036008"},{"id":"T68302","span":{"begin":65,"end":66},"obj":"PR:000036008;CHEBI:16382;CHEBI:16382"},{"id":"T53701","span":{"begin":70,"end":73},"obj":"CHEBI:37886;CHEBI:37886;PR:000036009"},{"id":"T10363","span":{"begin":74,"end":76},"obj":"PR:000036009"},{"id":"T56333","span":{"begin":93,"end":103},"obj":"MOP:0000619"},{"id":"T27917","span":{"begin":107,"end":117},"obj":"CHEBI:3165;CHEBI:3165"},{"id":"T15920","span":{"begin":171,"end":181},"obj":"CHEBI:3165;CHEBI:3165"},{"id":"T33386","span":{"begin":192,"end":203},"obj":"UBERON:0001986;GO:0017156"},{"id":"T67450","span":{"begin":203,"end":213},"obj":"GO:0017156"},{"id":"T25824","span":{"begin":214,"end":226},"obj":"GO:0042311"},{"id":"T87208","span":{"begin":245,"end":258},"obj":"CHEBI:26333;CHEBI:26333"},{"id":"T9658","span":{"begin":263,"end":274},"obj":"CHEBI:16480;CHEBI:16480"}],"text":"ulted in improved cardiac function and alleviated collagen disposition (49). These experiments suggested that both ACE inhibitors and ARBs variably upregulated ACE2 expression (49). ARBs inhibited binding of Ang II to the AT1 receptor, which permitted circulating Ang II to be shun"}

{"project":"LitCovid-PubTator","denotations":[{"id":"720","span":{"begin":115,"end":118},"obj":"Gene"},{"id":"721","span":{"begin":160,"end":164},"obj":"Gene"},{"id":"722","span":{"begin":208,"end":214},"obj":"Gene"},{"id":"723","span":{"begin":264,"end":270},"obj":"Gene"}],"attributes":[{"id":"A720","pred":"tao:has_database_id","subj":"720","obj":"Gene:11421"},{"id":"A721","pred":"tao:has_database_id","subj":"721","obj":"Gene:70008"},{"id":"A722","pred":"tao:has_database_id","subj":"722","obj":"Gene:11606"},{"id":"A723","pred":"tao:has_database_id","subj":"723","obj":"Gene:11606"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"ulted in improved cardiac function and alleviated collagen disposition (49). These experiments suggested that both ACE inhibitors and ARBs variably upregulated ACE2 expression (49). ARBs inhibited binding of Ang II to the AT1 receptor, which permitted circulating Ang II to be shun"}

{"project":"2_test","denotations":[{"id":"32305401-28656296-55252962","span":{"begin":72,"end":74},"obj":"28656296"},{"id":"32305401-28656296-55252963","span":{"begin":177,"end":179},"obj":"28656296"}],"text":"ulted in improved cardiac function and alleviated collagen disposition (49). These experiments suggested that both ACE inhibitors and ARBs variably upregulated ACE2 expression (49). ARBs inhibited binding of Ang II to the AT1 receptor, which permitted circulating Ang II to be shun"}