PMC:7160614 / 4222-5095 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7160614","sourcedb":"PMC","sourceid":"7160614","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7160614","text":"The current diagnostic criterion for COVID-19 is the positive result of a nucleic acid test by real-time reverse transcription polymerase chain reaction (RT-PCR) or next-generation sequencing [14]. However, false-negative results caused by unstable specimen processing are relatively high in clinical practice, which has worsened the spread of the outbreak [15–18]. Moreover, laboratory testing for SARS-CoV-2 requires a rigorous platform, which is not assembled in all hospitals. Thus, this requires specimen transfer, which may delay diagnosis for days. Early and accurate diagnosis is crucial, particularly for critically ill patients who need emergency surgery, and with pneumonia complications. To solve these problems, we hypothesize that a diagnostic model can be developed based on CT imaging and clinical manifestations alone, independent of the nucleic acid 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