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LitCovid-PD-FMA-UBERON

LitCovid-PD-UBERON

LitCovid-PD-MONDO

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T85","span":{"begin":110,"end":118},"obj":"Disease"},{"id":"T86","span":{"begin":279,"end":287},"obj":"Disease"},{"id":"T87","span":{"begin":1310,"end":1318},"obj":"Disease"},{"id":"T88","span":{"begin":2774,"end":2782},"obj":"Disease"}],"attributes":[{"id":"A85","pred":"mondo_id","subj":"T85","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A86","pred":"mondo_id","subj":"T86","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A87","pred":"mondo_id","subj":"T87","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A88","pred":"mondo_id","subj":"T88","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"}],"text":"In “Expert Recommendations from the Chinese Medical Association Radiology Branch,” chest CT manifestations of COVID-19 are divided into three stages: early, advanced, and severe, based on the extent of lesion involvement [15]. This current clinical guideline recommends dividing COVID-19 into four stages according to the time of onset and the response of body to the virus with additional dissipation stage (Fig. 4).Early stage: Chest CT shows single or multiple scattered patchy or conglomerate ground glass opacities, predominantly in the middle and lower lungs and along the bronchovascular bundles. These ground glass lesions are often located in peripheral and subpleural areas of the lung. Intra- and interlobular septal thickening sometimes present in the areas of ground glass opacity can give a crazy paving pattern. The pathological process during this stage is dilatation and congestion of the alveolar septal capillary, exudation of fluid in alveolar cavity, and interlobular interstitial edema [19]. One patient had normal chest CT at initial presentation; however, 3 days later the disease progressed and developed a solitary rounded ground glass lesion in the right lower lobe, indicating this pattern may represent the very first radiologically visible manifestation in patients infected with SARS-CoV-2 [24].\nAdvanced stage: At this stage, chest CTs will show new lesions that are similar to the earlier lesions described above. In addition, findings from the early stage of disease increase in density and extent, coexisting with the new areas of disease. As areas of consolidation grow, air bronchograms are often present in the areas of consolidation. A previous case report described a patient who had evolved into a mixed pattern of ground glass opacities and consolidation by 15 after onset of symptoms [27]. The pathological features in this stage are the accumulation of a cell-rich exudate in the alveolar cavity, vascular expansion, and exudation in the interstitium. The fibrous exudation connects each alveolus through the interalveolar space to form a fusion state [19].\nSevere stage: As the disease further progresses, chest CT shows diffuse consolidation of the lungs of varying density secondary to the fibrous exudate into the alveolar cavity, air bronchograms, and bronchial dilation. Non-consolidated areas of the lung appear as patchy ground glass opacity. When most of the lungs are involved, the lungs appear as a “whited out lung.” The pleura is thickened and there can be a small amount of pleural effusion.\nDissipation stage: Images show gradual resolution of the ground glass opacity and consolidation in the lungs with some residual curvilinear opacities compatible with fibrosis.\nFig. 4 CT manifestations of different stages of COVID-19"}

LitCovid-PD-CLO

LitCovid-sentences

{"project":"LitCovid-sentences","denotations":[{"id":"T124","span":{"begin":0,"end":226},"obj":"Sentence"},{"id":"T125","span":{"begin":227,"end":429},"obj":"Sentence"},{"id":"T126","span":{"begin":430,"end":603},"obj":"Sentence"},{"id":"T127","span":{"begin":604,"end":696},"obj":"Sentence"},{"id":"T128","span":{"begin":697,"end":826},"obj":"Sentence"},{"id":"T129","span":{"begin":827,"end":1013},"obj":"Sentence"},{"id":"T130","span":{"begin":1014,"end":1326},"obj":"Sentence"},{"id":"T131","span":{"begin":1327,"end":1342},"obj":"Sentence"},{"id":"T132","span":{"begin":1343,"end":1446},"obj":"Sentence"},{"id":"T133","span":{"begin":1447,"end":1574},"obj":"Sentence"},{"id":"T134","span":{"begin":1575,"end":1672},"obj":"Sentence"},{"id":"T135","span":{"begin":1673,"end":1832},"obj":"Sentence"},{"id":"T136","span":{"begin":1833,"end":1995},"obj":"Sentence"},{"id":"T137","span":{"begin":1996,"end":2101},"obj":"Sentence"},{"id":"T138","span":{"begin":2102,"end":2115},"obj":"Sentence"},{"id":"T139","span":{"begin":2116,"end":2320},"obj":"Sentence"},{"id":"T140","span":{"begin":2321,"end":2394},"obj":"Sentence"},{"id":"T141","span":{"begin":2395,"end":2549},"obj":"Sentence"},{"id":"T142","span":{"begin":2550,"end":2568},"obj":"Sentence"},{"id":"T143","span":{"begin":2569,"end":2725},"obj":"Sentence"},{"id":"T144","span":{"begin":2726,"end":2782},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"In “Expert Recommendations from the Chinese Medical Association Radiology Branch,” chest CT manifestations of COVID-19 are divided into three stages: early, advanced, and severe, based on the extent of lesion involvement [15]. This current clinical guideline recommends dividing COVID-19 into four stages according to the time of onset and the response of body to the virus with additional dissipation stage (Fig. 4).Early stage: Chest CT shows single or multiple scattered patchy or conglomerate ground glass opacities, predominantly in the middle and lower lungs and along the bronchovascular bundles. These ground glass lesions are often located in peripheral and subpleural areas of the lung. Intra- and interlobular septal thickening sometimes present in the areas of ground glass opacity can give a crazy paving pattern. The pathological process during this stage is dilatation and congestion of the alveolar septal capillary, exudation of fluid in alveolar cavity, and interlobular interstitial edema [19]. One patient had normal chest CT at initial presentation; however, 3 days later the disease progressed and developed a solitary rounded ground glass lesion in the right lower lobe, indicating this pattern may represent the very first radiologically visible manifestation in patients infected with SARS-CoV-2 [24].\nAdvanced stage: At this stage, chest CTs will show new lesions that are similar to the earlier lesions described above. In addition, findings from the early stage of disease increase in density and extent, coexisting with the new areas of disease. As areas of consolidation grow, air bronchograms are often present in the areas of consolidation. A previous case report described a patient who had evolved into a mixed pattern of ground glass opacities and consolidation by 15 after onset of symptoms [27]. The pathological features in this stage are the accumulation of a cell-rich exudate in the alveolar cavity, vascular expansion, and exudation in the interstitium. The fibrous exudation connects each alveolus through the interalveolar space to form a fusion state [19].\nSevere stage: As the disease further progresses, chest CT shows diffuse consolidation of the lungs of varying density secondary to the fibrous exudate into the alveolar cavity, air bronchograms, and bronchial dilation. Non-consolidated areas of the lung appear as patchy ground glass opacity. When most of the lungs are involved, the lungs appear as a “whited out lung.” The pleura is thickened and there can be a small amount of pleural effusion.\nDissipation stage: Images show gradual resolution of the ground glass opacity and consolidation in the lungs with some residual curvilinear opacities compatible with fibrosis.\nFig. 4 CT manifestations of different stages of COVID-19"}

LitCovid-PD-HP

{"project":"LitCovid-PD-HP","denotations":[{"id":"T25","span":{"begin":1002,"end":1007},"obj":"Phenotype"},{"id":"T26","span":{"begin":2532,"end":2548},"obj":"Phenotype"}],"attributes":[{"id":"A25","pred":"hp_id","subj":"T25","obj":"http://purl.obolibrary.org/obo/HP_0000969"},{"id":"A26","pred":"hp_id","subj":"T26","obj":"http://purl.obolibrary.org/obo/HP_0002202"}],"text":"In “Expert Recommendations from the Chinese Medical Association Radiology Branch,” chest CT manifestations of COVID-19 are divided into three stages: early, advanced, and severe, based on the extent of lesion involvement [15]. This current clinical guideline recommends dividing COVID-19 into four stages according to the time of onset and the response of body to the virus with additional dissipation stage (Fig. 4).Early stage: Chest CT shows single or multiple scattered patchy or conglomerate ground glass opacities, predominantly in the middle and lower lungs and along the bronchovascular bundles. These ground glass lesions are often located in peripheral and subpleural areas of the lung. Intra- and interlobular septal thickening sometimes present in the areas of ground glass opacity can give a crazy paving pattern. The pathological process during this stage is dilatation and congestion of the alveolar septal capillary, exudation of fluid in alveolar cavity, and interlobular interstitial edema [19]. One patient had normal chest CT at initial presentation; however, 3 days later the disease progressed and developed a solitary rounded ground glass lesion in the right lower lobe, indicating this pattern may represent the very first radiologically visible manifestation in patients infected with SARS-CoV-2 [24].\nAdvanced stage: At this stage, chest CTs will show new lesions that are similar to the earlier lesions described above. In addition, findings from the early stage of disease increase in density and extent, coexisting with the new areas of disease. As areas of consolidation grow, air bronchograms are often present in the areas of consolidation. A previous case report described a patient who had evolved into a mixed pattern of ground glass opacities and consolidation by 15 after onset of symptoms [27]. The pathological features in this stage are the accumulation of a cell-rich exudate in the alveolar cavity, vascular expansion, and exudation in the interstitium. The fibrous exudation connects each alveolus through the interalveolar space to form a fusion state [19].\nSevere stage: As the disease further progresses, chest CT shows diffuse consolidation of the lungs of varying density secondary to the fibrous exudate into the alveolar cavity, air bronchograms, and bronchial dilation. Non-consolidated areas of the lung appear as patchy ground glass opacity. When most of the lungs are involved, the lungs appear as a “whited out lung.” The pleura is thickened and there can be a small amount of pleural effusion.\nDissipation stage: Images show gradual resolution of the ground glass opacity and consolidation in the lungs with some residual curvilinear opacities compatible with fibrosis.\nFig. 4 CT manifestations of different stages of COVID-19"}

MyTest

{"project":"MyTest","denotations":[{"id":"32296940-32029004-29373577","span":{"begin":1009,"end":1011},"obj":"32029004"},{"id":"32296940-32029004-29373578","span":{"begin":2097,"end":2099},"obj":"32029004"}],"namespaces":[{"prefix":"_base","uri":"https://www.uniprot.org/uniprot/testbase"},{"prefix":"UniProtKB","uri":"https://www.uniprot.org/uniprot/"},{"prefix":"uniprot","uri":"https://www.uniprot.org/uniprotkb/"}],"text":"In “Expert Recommendations from the Chinese Medical Association Radiology Branch,” chest CT manifestations of COVID-19 are divided into three stages: early, advanced, and severe, based on the extent of lesion involvement [15]. This current clinical guideline recommends dividing COVID-19 into four stages according to the time of onset and the response of body to the virus with additional dissipation stage (Fig. 4).Early stage: Chest CT shows single or multiple scattered patchy or conglomerate ground glass opacities, predominantly in the middle and lower lungs and along the bronchovascular bundles. These ground glass lesions are often located in peripheral and subpleural areas of the lung. Intra- and interlobular septal thickening sometimes present in the areas of ground glass opacity can give a crazy paving pattern. The pathological process during this stage is dilatation and congestion of the alveolar septal capillary, exudation of fluid in alveolar cavity, and interlobular interstitial edema [19]. One patient had normal chest CT at initial presentation; however, 3 days later the disease progressed and developed a solitary rounded ground glass lesion in the right lower lobe, indicating this pattern may represent the very first radiologically visible manifestation in patients infected with SARS-CoV-2 [24].\nAdvanced stage: At this stage, chest CTs will show new lesions that are similar to the earlier lesions described above. In addition, findings from the early stage of disease increase in density and extent, coexisting with the new areas of disease. As areas of consolidation grow, air bronchograms are often present in the areas of consolidation. A previous case report described a patient who had evolved into a mixed pattern of ground glass opacities and consolidation by 15 after onset of symptoms [27]. The pathological features in this stage are the accumulation of a cell-rich exudate in the alveolar cavity, vascular expansion, and exudation in the interstitium. The fibrous exudation connects each alveolus through the interalveolar space to form a fusion state [19].\nSevere stage: As the disease further progresses, chest CT shows diffuse consolidation of the lungs of varying density secondary to the fibrous exudate into the alveolar cavity, air bronchograms, and bronchial dilation. Non-consolidated areas of the lung appear as patchy ground glass opacity. When most of the lungs are involved, the lungs appear as a “whited out lung.” The pleura is thickened and there can be a small amount of pleural effusion.\nDissipation stage: Images show gradual resolution of the ground glass opacity and consolidation in the lungs with some residual curvilinear opacities compatible with fibrosis.\nFig. 4 CT manifestations of different stages of COVID-19"}

0_colil

{"project":"0_colil","denotations":[{"id":"32296940-32029004-67392","span":{"begin":1009,"end":1011},"obj":"32029004"},{"id":"32296940-32029004-67393","span":{"begin":2097,"end":2099},"obj":"32029004"}],"text":"In “Expert Recommendations from the Chinese Medical Association Radiology Branch,” chest CT manifestations of COVID-19 are divided into three stages: early, advanced, and severe, based on the extent of lesion involvement [15]. This current clinical guideline recommends dividing COVID-19 into four stages according to the time of onset and the response of body to the virus with additional dissipation stage (Fig. 4).Early stage: Chest CT shows single or multiple scattered patchy or conglomerate ground glass opacities, predominantly in the middle and lower lungs and along the bronchovascular bundles. These ground glass lesions are often located in peripheral and subpleural areas of the lung. Intra- and interlobular septal thickening sometimes present in the areas of ground glass opacity can give a crazy paving pattern. The pathological process during this stage is dilatation and congestion of the alveolar septal capillary, exudation of fluid in alveolar cavity, and interlobular interstitial edema [19]. One patient had normal chest CT at initial presentation; however, 3 days later the disease progressed and developed a solitary rounded ground glass lesion in the right lower lobe, indicating this pattern may represent the very first radiologically visible manifestation in patients infected with SARS-CoV-2 [24].\nAdvanced stage: At this stage, chest CTs will show new lesions that are similar to the earlier lesions described above. In addition, findings from the early stage of disease increase in density and extent, coexisting with the new areas of disease. As areas of consolidation grow, air bronchograms are often present in the areas of consolidation. A previous case report described a patient who had evolved into a mixed pattern of ground glass opacities and consolidation by 15 after onset of symptoms [27]. The pathological features in this stage are the accumulation of a cell-rich exudate in the alveolar cavity, vascular expansion, and exudation in the interstitium. The fibrous exudation connects each alveolus through the interalveolar space to form a fusion state [19].\nSevere stage: As the disease further progresses, chest CT shows diffuse consolidation of the lungs of varying density secondary to the fibrous exudate into the alveolar cavity, air bronchograms, and bronchial dilation. Non-consolidated areas of the lung appear as patchy ground glass opacity. When most of the lungs are involved, the lungs appear as a “whited out lung.” The pleura is thickened and there can be a small amount of pleural effusion.\nDissipation stage: Images show gradual resolution of the ground glass opacity and consolidation in the lungs with some residual curvilinear opacities compatible with fibrosis.\nFig. 4 CT manifestations of different stages of COVID-19"}

TEST0

{"project":"TEST0","denotations":[{"id":"32296940-182-188-67392","span":{"begin":1009,"end":1011},"obj":"[\"32029004\"]"},{"id":"32296940-101-107-67393","span":{"begin":2097,"end":2099},"obj":"[\"32029004\"]"}],"text":"In “Expert Recommendations from the Chinese Medical Association Radiology Branch,” chest CT manifestations of COVID-19 are divided into three stages: early, advanced, and severe, based on the extent of lesion involvement [15]. This current clinical guideline recommends dividing COVID-19 into four stages according to the time of onset and the response of body to the virus with additional dissipation stage (Fig. 4).Early stage: Chest CT shows single or multiple scattered patchy or conglomerate ground glass opacities, predominantly in the middle and lower lungs and along the bronchovascular bundles. These ground glass lesions are often located in peripheral and subpleural areas of the lung. Intra- and interlobular septal thickening sometimes present in the areas of ground glass opacity can give a crazy paving pattern. The pathological process during this stage is dilatation and congestion of the alveolar septal capillary, exudation of fluid in alveolar cavity, and interlobular interstitial edema [19]. One patient had normal chest CT at initial presentation; however, 3 days later the disease progressed and developed a solitary rounded ground glass lesion in the right lower lobe, indicating this pattern may represent the very first radiologically visible manifestation in patients infected with SARS-CoV-2 [24].\nAdvanced stage: At this stage, chest CTs will show new lesions that are similar to the earlier lesions described above. In addition, findings from the early stage of disease increase in density and extent, coexisting with the new areas of disease. As areas of consolidation grow, air bronchograms are often present in the areas of consolidation. A previous case report described a patient who had evolved into a mixed pattern of ground glass opacities and consolidation by 15 after onset of symptoms [27]. The pathological features in this stage are the accumulation of a cell-rich exudate in the alveolar cavity, vascular expansion, and exudation in the interstitium. The fibrous exudation connects each alveolus through the interalveolar space to form a fusion state [19].\nSevere stage: As the disease further progresses, chest CT shows diffuse consolidation of the lungs of varying density secondary to the fibrous exudate into the alveolar cavity, air bronchograms, and bronchial dilation. Non-consolidated areas of the lung appear as patchy ground glass opacity. When most of the lungs are involved, the lungs appear as a “whited out lung.” The pleura is thickened and there can be a small amount of pleural effusion.\nDissipation stage: Images show gradual resolution of the ground glass opacity and consolidation in the lungs with some residual curvilinear opacities compatible with fibrosis.\nFig. 4 CT manifestations of different stages of COVID-19"}

2_test

{"project":"2_test","denotations":[{"id":"32296940-32029004-29373577","span":{"begin":1009,"end":1011},"obj":"32029004"},{"id":"32296940-32029004-29373578","span":{"begin":2097,"end":2099},"obj":"32029004"}],"text":"In “Expert Recommendations from the Chinese Medical Association Radiology Branch,” chest CT manifestations of COVID-19 are divided into three stages: early, advanced, and severe, based on the extent of lesion involvement [15]. This current clinical guideline recommends dividing COVID-19 into four stages according to the time of onset and the response of body to the virus with additional dissipation stage (Fig. 4).Early stage: Chest CT shows single or multiple scattered patchy or conglomerate ground glass opacities, predominantly in the middle and lower lungs and along the bronchovascular bundles. These ground glass lesions are often located in peripheral and subpleural areas of the lung. Intra- and interlobular septal thickening sometimes present in the areas of ground glass opacity can give a crazy paving pattern. The pathological process during this stage is dilatation and congestion of the alveolar septal capillary, exudation of fluid in alveolar cavity, and interlobular interstitial edema [19]. One patient had normal chest CT at initial presentation; however, 3 days later the disease progressed and developed a solitary rounded ground glass lesion in the right lower lobe, indicating this pattern may represent the very first radiologically visible manifestation in patients infected with SARS-CoV-2 [24].\nAdvanced stage: At this stage, chest CTs will show new lesions that are similar to the earlier lesions described above. In addition, findings from the early stage of disease increase in density and extent, coexisting with the new areas of disease. As areas of consolidation grow, air bronchograms are often present in the areas of consolidation. A previous case report described a patient who had evolved into a mixed pattern of ground glass opacities and consolidation by 15 after onset of symptoms [27]. The pathological features in this stage are the accumulation of a cell-rich exudate in the alveolar cavity, vascular expansion, and exudation in the interstitium. The fibrous exudation connects each alveolus through the interalveolar space to form a fusion state [19].\nSevere stage: As the disease further progresses, chest CT shows diffuse consolidation of the lungs of varying density secondary to the fibrous exudate into the alveolar cavity, air bronchograms, and bronchial dilation. Non-consolidated areas of the lung appear as patchy ground glass opacity. When most of the lungs are involved, the lungs appear as a “whited out lung.” The pleura is thickened and there can be a small amount of pleural effusion.\nDissipation stage: Images show gradual resolution of the ground glass opacity and consolidation in the lungs with some residual curvilinear opacities compatible with fibrosis.\nFig. 4 CT manifestations of different stages of COVID-19"}

LitCovid-PubTator

PMC:7156903 / 16404-19186 JSONTXT

Annnotations TAB JSON ListView MergeView

PMC:7156903 / 16404-19186 JSON TXT