PMC:7156291 / 13761-17982 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7156291","sourcedb":"PMC","sourceid":"7156291","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7156291","text":"Evolution of CT findings in patients with COVID-19\nThe initial CTs of 4 out of 88 (4.5%) patients were negative. Two of these four patients had their baseline CT during days 1–3, one during days 4–7, and one during days 8–10 of disease. Subsequently, CT images of one patient remained negative even during days 8–10, and other patients developed CT abnormalities.\nThere were significant differences between the time interval groups after disease onset in proportions of patients with both GGO and consolidation (χ2 = 22.2, p \u003c 0.01) and the combination of GGO, consolidation, and linear opacities (χ2 = 21.5, p \u003c 0.01) (Table 2). A proportion of patients with GGO and consolidation presented a decreasing trend during the 21 days after disease onset (y = 0.48–0.09x, p \u003c 0.01), while a proportion of patient with all three findings including ground glass opacities, consolidation, and linear opacities presented an increasing trend (y = 0.12–0.11x, p \u003c 0.01). No significant difference was found in the proportions of patients with other CT findings or total lung severity score.\nTable 2 Evolution of CT findings and total lung severity scores of patients with COVID-19 within 21 days after disease onset\nCharacteristic Time after disease onset χ2 p value\nDays 0–3 (n = 37) Days 4–7 (n = 69) Days 8–10 (n = 53) Days 11–14 (n = 49) Days 15–21 (n = 25)\nPulmonary opacities\n  GGO only 8 (21.6) 13 (18.8) 7 (13.2) 4 (8.2) 1 (4.0) 6.6 0.16\n  GGO and consolidation 12 (32.4) 26 (37.7) 8 (15.1) 5 (10.1) 1 (4.0) 22.2 \u003c 0.01\n  GGO and linear opacities 2 (5.4) 2 (2.9) 4 (7.5) 2 (4.1) 2 (8.0) 1.87 0.76\n  Consolidation only 1 (2.8) 6 (8.7) 3 (5.7) 4 (8.2) 1 (4.0) 1.98 0.74\n  Consolidation and linear opacities 0 (0) 2 (2.9) 4 (7.5) 4 (8.2) 3 (12.0) 6.0 0.19\n  GGO, consolidation, and linear opacities 12 (32.4) 19 (27.5) 25 (47.2) 30 (61.2) 17 (68.0) 21.5 \u003c 0.01\n  Negative CT 2 (5.4) 1 (1.5) 2 (3.8) 0 (0.0) 0 (0.0) 4.3 0.36\nOther findings\n  Discrete pulmonary nodules 4 (10.8) 4 (5.8) 3 (5.7) 1 (2.0) 0 (0) 4.8 0.36\n  Pleural effusion 0 (0) 0 (0) 0 (0) 0 (0) 0 (0) – –\n  Lymphadenopathy 0 (0) 0 (0) 0 (0) 0 (0) 0 (0) – –\n  Cavitation 3 (8.1) 3 (4.3) 1 (1.9) 2 (4.1) 1 (4.0) 2.1 0.72\nTotal lung severity score\n  Mean ± SD 3.9 ± 2.7 4.8 ± 2.9 4.9 ± 2.8 5.3 ± 3.3 5.2 ± 2.8 – 0.29\n  Median (range) 4 (0–10) 5 (0–12) 5 (0–11) 5 (1–13) 5 (1–11) – –\nNumbers in parentheses are percentages\nn number of patients, GGO ground glass opacities\nNone of the patients had pleural effusions or intrathoracic lymphadenopathy during the follow-up period. Some of the patients had cavitation on CT, but these are thought to represent pre-existing conditions as none of the patients in the study cohort developed cavitation on follow-up CT.\nFigures 3 and 4 show the evolution of CT findings of two patients with COVID-19 pneumonia.\nFig. 3 A 54-year-old woman with exposure to a COVID-infected patient presented with fever, cough, and low back pain for 2 days and remains hospitalized. a–c CT shows left lower lobe GGO on day 2. The total severity score is 1. d–f CT on day 7 shows a significant increase in GGO in both lungs. The severity score of the left lower lobe is 2. The total severity score is 5. g–i CT on day 9 shows bilateral GGO and subpleural consolidation. The severity score of the left lower lobe is 3. The total severity score is 9. j–l CT on day 11 shows diffuse GGO and linear opacities (thick arrow). The severity score of the left lower lobe is 4. The total severity score is 12\nFig. 4 A 24-year-old man with exposure to a COVID-infected patient presented with fever and cough for 1 day and remains hospitalized currently. a–e CT scan shows GGO in the subpleural left lower lobe on day 1 (thick arrow). The overall total severity score is 1. f–j CT on day 4 shows enlarging GGO in left lower lobes (thick arrow). The overall total severity score is 3. k–o CT on day 8 shows increased GGO in bilateral lower lobes. The total severity score was 5. p–t CT obtained on day 11 shows bilateral ground glass opacities and linear opacities (thick arrow). The overall total severity score was 7. u–y CT obtained on day 15 shows improvement of bilateral lower lobe GGO and atoll sign (thick arrow). The overall total severity score is 5","divisions":[{"label":"td","span":{"begin":2029,"end":2034}},{"label":"title","span":{"begin":0,"end":50}},{"label":"p","span":{"begin":51,"end":363}},{"label":"p","span":{"begin":364,"end":2425}},{"label":"table-wrap","span":{"begin":1080,"end":2425}},{"label":"label","span":{"begin":1080,"end":1087}},{"label":"caption","span":{"begin":1088,"end":1204}},{"label":"p","span":{"begin":1088,"end":1204}},{"label":"table","span":{"begin":1205,"end":2337}},{"label":"tr","span":{"begin":1205,"end":1255}},{"label":"th","span":{"begin":1205,"end":1219}},{"label":"th","span":{"begin":1220,"end":1244}},{"label":"th","span":{"begin":1245,"end":1247}},{"label":"th","span":{"begin":1248,"end":1255}},{"label":"tr","span":{"begin":1256,"end":1350}},{"label":"th","span":{"begin":1256,"end":1273}},{"label":"th","span":{"begin":1274,"end":1291}},{"label":"th","span":{"begin":1292,"end":1310}},{"label":"th","span":{"begin":1311,"end":1330}},{"label":"th","span":{"begin":1331,"end":1350}},{"label":"tr","span":{"begin":1351,"end":1370}},{"label":"td","span":{"begin":1351,"end":1370}},{"label":"tr","span":{"begin":1371,"end":1434}},{"label":"td","span":{"begin":1371,"end":1381}},{"label":"td","span":{"begin":1382,"end":1390}},{"label":"td","span":{"begin":1391,"end":1400}},{"label":"td","span":{"begin":1401,"end":1409}},{"label":"td","span":{"begin":1410,"end":1417}},{"label":"td","span":{"begin":1418,"end":1425}},{"label":"td","span":{"begin":1426,"end":1429}},{"label":"td","span":{"begin":1430,"end":1434}},{"label":"tr","span":{"begin":1435,"end":1516}},{"label":"td","span":{"begin":1435,"end":1458}},{"label":"td","span":{"begin":1459,"end":1468}},{"label":"td","span":{"begin":1469,"end":1478}},{"label":"td","span":{"begin":1479,"end":1487}},{"label":"td","span":{"begin":1488,"end":1496}},{"label":"td","span":{"begin":1497,"end":1504}},{"label":"td","span":{"begin":1505,"end":1509}},{"label":"td","span":{"begin":1510,"end":1516}},{"label":"tr","span":{"begin":1517,"end":1593}},{"label":"td","span":{"begin":1517,"end":1543}},{"label":"td","span":{"begin":1544,"end":1551}},{"label":"td","span":{"begin":1552,"end":1559}},{"label":"td","span":{"begin":1560,"end":1567}},{"label":"td","span":{"begin":1568,"end":1575}},{"label":"td","span":{"begin":1576,"end":1583}},{"label":"td","span":{"begin":1584,"end":1588}},{"label":"td","span":{"begin":1589,"end":1593}},{"label":"tr","span":{"begin":1594,"end":1664}},{"label":"td","span":{"begin":1594,"end":1614}},{"label":"td","span":{"begin":1615,"end":1622}},{"label":"td","span":{"begin":1623,"end":1630}},{"label":"td","span":{"begin":1631,"end":1638}},{"label":"td","span":{"begin":1639,"end":1646}},{"label":"td","span":{"begin":1647,"end":1654}},{"label":"td","span":{"begin":1655,"end":1659}},{"label":"td","span":{"begin":1660,"end":1664}},{"label":"tr","span":{"begin":1665,"end":1749}},{"label":"td","span":{"begin":1665,"end":1701}},{"label":"td","span":{"begin":1702,"end":1707}},{"label":"td","span":{"begin":1708,"end":1715}},{"label":"td","span":{"begin":1716,"end":1723}},{"label":"td","span":{"begin":1724,"end":1731}},{"label":"td","span":{"begin":1732,"end":1740}},{"label":"td","span":{"begin":1741,"end":1744}},{"label":"td","span":{"begin":1745,"end":1749}},{"label":"tr","span":{"begin":1750,"end":1854}},{"label":"td","span":{"begin":1750,"end":1792}},{"label":"td","span":{"begin":1793,"end":1802}},{"label":"td","span":{"begin":1803,"end":1812}},{"label":"td","span":{"begin":1813,"end":1822}},{"label":"td","span":{"begin":1823,"end":1832}},{"label":"td","span":{"begin":1833,"end":1842}},{"label":"td","span":{"begin":1843,"end":1847}},{"label":"td","span":{"begin":1848,"end":1854}},{"label":"tr","span":{"begin":1855,"end":1917}},{"label":"td","span":{"begin":1855,"end":1868}},{"label":"td","span":{"begin":1869,"end":1876}},{"label":"td","span":{"begin":1877,"end":1884}},{"label":"td","span":{"begin":1885,"end":1892}},{"label":"td","span":{"begin":1893,"end":1900}},{"label":"td","span":{"begin":1901,"end":1908}},{"label":"td","span":{"begin":1909,"end":1912}},{"label":"td","span":{"begin":1913,"end":1917}},{"label":"tr","span":{"begin":1918,"end":1932}},{"label":"td","span":{"begin":1918,"end":1932}},{"label":"tr","span":{"begin":1933,"end":2009}},{"label":"td","span":{"begin":1933,"end":1961}},{"label":"td","span":{"begin":1962,"end":1970}},{"label":"td","span":{"begin":1971,"end":1978}},{"label":"td","span":{"begin":1979,"end":1986}},{"label":"td","span":{"begin":1987,"end":1994}},{"label":"td","span":{"begin":1995,"end":2000}},{"label":"td","span":{"begin":2001,"end":2004}},{"label":"td","span":{"begin":2005,"end":2009}},{"label":"tr","span":{"begin":2010,"end":2062}},{"label":"td","span":{"begin":2010,"end":2028}},{"label":"td","span":{"begin":2035,"end":2040}},{"label":"td","span":{"begin":2041,"end":2046}},{"label":"td","span":{"begin":2047,"end":2052}},{"label":"td","span":{"begin":2053,"end":2058}},{"label":"td","span":{"begin":2059,"end":2060}},{"label":"td","span":{"begin":2061,"end":2062}},{"label":"tr","span":{"begin":2063,"end":2114}},{"label":"td","span":{"begin":2063,"end":2080}},{"label":"td","span":{"begin":2081,"end":2086}},{"label":"td","span":{"begin":2087,"end":2092}},{"label":"td","span":{"begin":2093,"end":2098}},{"label":"td","span":{"begin":2099,"end":2104}},{"label":"td","span":{"begin":2105,"end":2110}},{"label":"td","span":{"begin":2111,"end":2112}},{"label":"td","span":{"begin":2113,"end":2114}},{"label":"tr","span":{"begin":2115,"end":2176}},{"label":"td","span":{"begin":2115,"end":2127}},{"label":"td","span":{"begin":2128,"end":2135}},{"label":"td","span":{"begin":2136,"end":2143}},{"label":"td","span":{"begin":2144,"end":2151}},{"label":"td","span":{"begin":2152,"end":2159}},{"label":"td","span":{"begin":2160,"end":2167}},{"label":"td","span":{"begin":2168,"end":2171}},{"label":"td","span":{"begin":2172,"end":2176}},{"label":"tr","span":{"begin":2177,"end":2202}},{"label":"td","span":{"begin":2177,"end":2202}},{"label":"tr","span":{"begin":2203,"end":2271}},{"label":"td","span":{"begin":2203,"end":2214}},{"label":"td","span":{"begin":2215,"end":2224}},{"label":"td","span":{"begin":2225,"end":2234}},{"label":"td","span":{"begin":2235,"end":2244}},{"label":"td","span":{"begin":2245,"end":2254}},{"label":"td","span":{"begin":2255,"end":2264}},{"label":"td","span":{"begin":2265,"end":2266}},{"label":"td","span":{"begin":2267,"end":2271}},{"label":"tr","span":{"begin":2272,"end":2337}},{"label":"td","span":{"begin":2272,"end":2288}},{"label":"td","span":{"begin":2289,"end":2297}},{"label":"td","span":{"begin":2298,"end":2306}},{"label":"td","span":{"begin":2307,"end":2315}},{"label":"td","span":{"begin":2316,"end":2324}},{"label":"td","span":{"begin":2325,"end":2333}},{"label":"td","span":{"begin":2334,"end":2335}},{"label":"td","span":{"begin":2336,"end":2337}},{"label":"table-wrap-foot","span":{"begin":2338,"end":2425}},{"label":"p","span":{"begin":2338,"end":2376}},{"label":"p","span":{"begin":2377,"end":2425}},{"label":"p","span":{"begin":2426,"end":2714}},{"label":"figure","span":{"begin":2806,"end":3473}},{"label":"label","span":{"begin":2806,"end":2812}},{"label":"caption","span":{"begin":2813,"end":3473}},{"label":"p","span":{"begin":2813,"end":3473}},{"label":"label","span":{"begin":3474,"end":3480}}],"tracks":[{"project":"LitCovid-PubTator","denotations":[{"id":"266","span":{"begin":28,"end":36},"obj":"Species"},{"id":"267","span":{"begin":42,"end":50},"obj":"Disease"},{"id":"272","span":{"begin":89,"end":97},"obj":"Species"},{"id":"273","span":{"begin":131,"end":139},"obj":"Species"},{"id":"274","span":{"begin":268,"end":275},"obj":"Species"},{"id":"275","span":{"begin":327,"end":335},"obj":"Species"},{"id":"278","span":{"begin":2012,"end":2028},"obj":"Disease"},{"id":"279","span":{"begin":2065,"end":2080},"obj":"Disease"},{"id":"282","span":{"begin":1147,"end":1155},"obj":"Species"},{"id":"283","span":{"begin":1161,"end":1169},"obj":"Disease"},{"id":"285","span":{"begin":2389,"end":2397},"obj":"Species"},{"id":"290","span":{"begin":470,"end":478},"obj":"Species"},{"id":"291","span":{"begin":646,"end":654},"obj":"Species"},{"id":"292","span":{"begin":800,"end":807},"obj":"Species"},{"id":"293","span":{"begin":1018,"end":1026},"obj":"Species"},{"id":"299","span":{"begin":2438,"end":2446},"obj":"Species"},{"id":"300","span":{"begin":2543,"end":2551},"obj":"Species"},{"id":"301","span":{"begin":2648,"end":2656},"obj":"Species"},{"id":"302","span":{"begin":2451,"end":2468},"obj":"Disease"},{"id":"303","span":{"begin":2486,"end":2501},"obj":"Disease"},{"id":"310","span":{"begin":2827,"end":2832},"obj":"Species"},{"id":"311","span":{"begin":2867,"end":2874},"obj":"Species"},{"id":"312","span":{"begin":2852,"end":2866},"obj":"Disease"},{"id":"313","span":{"begin":2890,"end":2895},"obj":"Disease"},{"id":"314","span":{"begin":2897,"end":2902},"obj":"Disease"},{"id":"315","span":{"begin":2908,"end":2921},"obj":"Disease"},{"id":"320","span":{"begin":3533,"end":3540},"obj":"Species"},{"id":"321","span":{"begin":3518,"end":3532},"obj":"Disease"},{"id":"322","span":{"begin":3556,"end":3561},"obj":"Disease"},{"id":"323","span":{"begin":3566,"end":3571},"obj":"Disease"},{"id":"326","span":{"begin":2772,"end":2780},"obj":"Species"},{"id":"327","span":{"begin":2786,"end":2804},"obj":"Disease"}],"attributes":[{"id":"A266","pred":"tao:has_database_id","subj":"266","obj":"Tax:9606"},{"id":"A267","pred":"tao:has_database_id","subj":"267","obj":"MESH:C000657245"},{"id":"A272","pred":"tao:has_database_id","subj":"272","obj":"Tax:9606"},{"id":"A273","pred":"tao:has_database_id","subj":"273","obj":"Tax:9606"},{"id":"A274","pred":"tao:has_database_id","subj":"274","obj":"Tax:9606"},{"id":"A275","pred":"tao:has_database_id","subj":"275","obj":"Tax:9606"},{"id":"A278","pred":"tao:has_database_id","subj":"278","obj":"MESH:D010996"},{"id":"A279","pred":"tao:has_database_id","subj":"279","obj":"MESH:D008206"},{"id":"A282","pred":"tao:has_database_id","subj":"282","obj":"Tax:9606"},{"id":"A283","pred":"tao:has_database_id","subj":"283","obj":"MESH:C000657245"},{"id":"A285","pred":"tao:has_database_id","subj":"285","obj":"Tax:9606"},{"id":"A290","pred":"tao:has_database_id","subj":"290","obj":"Tax:9606"},{"id":"A291","pred":"tao:has_database_id","subj":"291","obj":"Tax:9606"},{"id":"A292","pred":"tao:has_database_id","subj":"292","obj":"Tax:9606"},{"id":"A293","pred":"tao:has_database_id","subj":"293","obj":"Tax:9606"},{"id":"A299","pred":"tao:has_database_id","subj":"299","obj":"Tax:9606"},{"id":"A300","pred":"tao:has_database_id","subj":"300","obj":"Tax:9606"},{"id":"A301","pred":"tao:has_database_id","subj":"301","obj":"Tax:9606"},{"id":"A302","pred":"tao:has_database_id","subj":"302","obj":"MESH:D010996"},{"id":"A303","pred":"tao:has_database_id","subj":"303","obj":"MESH:D008206"},{"id":"A310","pred":"tao:has_database_id","subj":"310","obj":"Tax:9606"},{"id":"A311","pred":"tao:has_database_id","subj":"311","obj":"Tax:9606"},{"id":"A312","pred":"tao:has_database_id","subj":"312","obj":"MESH:C000657245"},{"id":"A313","pred":"tao:has_database_id","subj":"313","obj":"MESH:D005334"},{"id":"A314","pred":"tao:has_database_id","subj":"314","obj":"MESH:D003371"},{"id":"A315","pred":"tao:has_database_id","subj":"315","obj":"MESH:D017116"},{"id":"A320","pred":"tao:has_database_id","subj":"320","obj":"Tax:9606"},{"id":"A321","pred":"tao:has_database_id","subj":"321","obj":"MESH:C000657245"},{"id":"A322","pred":"tao:has_database_id","subj":"322","obj":"MESH:D005334"},{"id":"A323","pred":"tao:has_database_id","subj":"323","obj":"MESH:D003371"},{"id":"A326","pred":"tao:has_database_id","subj":"326","obj":"Tax:9606"},{"id":"A327","pred":"tao:has_database_id","subj":"327","obj":"MESH:C000657245"},{"subj":"266","pred":"source","obj":"LitCovid-PubTator"},{"subj":"267","pred":"source","obj":"LitCovid-PubTator"},{"subj":"272","pred":"source","obj":"LitCovid-PubTator"},{"subj":"273","pred":"source","obj":"LitCovid-PubTator"},{"subj":"274","pred":"source","obj":"LitCovid-PubTator"},{"subj":"275","pred":"source","obj":"LitCovid-PubTator"},{"subj":"278","pred":"source","obj":"LitCovid-PubTator"},{"subj":"279","pred":"source","obj":"LitCovid-PubTator"},{"subj":"282","pred":"source","obj":"LitCovid-PubTator"},{"subj":"283","pred":"source","obj":"LitCovid-PubTator"},{"subj":"285","pred":"source","obj":"LitCovid-PubTator"},{"subj":"290","pred":"source","obj":"LitCovid-PubTator"},{"subj":"291","pred":"source","obj":"LitCovid-PubTator"},{"subj":"292","pred":"source","obj":"LitCovid-PubTator"},{"subj":"293","pred":"source","obj":"LitCovid-PubTator"},{"subj":"299","pred":"source","obj":"LitCovid-PubTator"},{"subj":"300","pred":"source","obj":"LitCovid-PubTator"},{"subj":"301","pred":"source","obj":"LitCovid-PubTator"},{"subj":"302","pred":"source","obj":"LitCovid-PubTator"},{"subj":"303","pred":"source","obj":"LitCovid-PubTator"},{"subj":"310","pred":"source","obj":"LitCovid-PubTator"},{"subj":"311","pred":"source","obj":"LitCovid-PubTator"},{"subj":"312","pred":"source","obj":"LitCovid-PubTator"},{"subj":"313","pred":"source","obj":"LitCovid-PubTator"},{"subj":"314","pred":"source","obj":"LitCovid-PubTator"},{"subj":"315","pred":"source","obj":"LitCovid-PubTator"},{"subj":"320","pred":"source","obj":"LitCovid-PubTator"},{"subj":"321","pred":"source","obj":"LitCovid-PubTator"},{"subj":"322","pred":"source","obj":"LitCovid-PubTator"},{"subj":"323","pred":"source","obj":"LitCovid-PubTator"},{"subj":"326","pred":"source","obj":"LitCovid-PubTator"},{"subj":"327","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T36","span":{"begin":1059,"end":1063},"obj":"Body_part"},{"id":"T37","span":{"begin":1123,"end":1127},"obj":"Body_part"},{"id":"T38","span":{"begin":2183,"end":2187},"obj":"Body_part"},{"id":"T39","span":{"begin":2912,"end":2916},"obj":"Body_part"},{"id":"T40","span":{"begin":2972,"end":2987},"obj":"Body_part"},{"id":"T41","span":{"begin":3093,"end":3098},"obj":"Body_part"},{"id":"T42","span":{"begin":3126,"end":3141},"obj":"Body_part"},{"id":"T43","span":{"begin":3271,"end":3286},"obj":"Body_part"},{"id":"T44","span":{"begin":3421,"end":3436},"obj":"Body_part"},{"id":"T45","span":{"begin":3658,"end":3673},"obj":"Body_part"},{"id":"T46","span":{"begin":3776,"end":3792},"obj":"Body_part"}],"attributes":[{"id":"A36","pred":"fma_id","subj":"T36","obj":"http://purl.org/sig/ont/fma/fma7195"},{"id":"A37","pred":"fma_id","subj":"T37","obj":"http://purl.org/sig/ont/fma/fma7195"},{"id":"A38","pred":"fma_id","subj":"T38","obj":"http://purl.org/sig/ont/fma/fma7195"},{"id":"A39","pred":"fma_id","subj":"T39","obj":"http://purl.org/sig/ont/fma/fma25056"},{"id":"A40","pred":"fma_id","subj":"T40","obj":"http://purl.org/sig/ont/fma/fma7371"},{"id":"A41","pred":"fma_id","subj":"T41","obj":"http://purl.org/sig/ont/fma/fma68877"},{"id":"A42","pred":"fma_id","subj":"T42","obj":"http://purl.org/sig/ont/fma/fma7371"},{"id":"A43","pred":"fma_id","subj":"T43","obj":"http://purl.org/sig/ont/fma/fma7371"},{"id":"A44","pred":"fma_id","subj":"T44","obj":"http://purl.org/sig/ont/fma/fma7371"},{"id":"A45","pred":"fma_id","subj":"T45","obj":"http://purl.org/sig/ont/fma/fma7371"},{"id":"A46","pred":"fma_id","subj":"T46","obj":"http://purl.org/sig/ont/fma/fma7371"},{"subj":"T36","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T37","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T38","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T39","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T40","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T41","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T42","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T43","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T44","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T45","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T46","pred":"source","obj":"LitCovid-PD-FMA-UBERON"}]},{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T23","span":{"begin":1059,"end":1063},"obj":"Body_part"},{"id":"T24","span":{"begin":1123,"end":1127},"obj":"Body_part"},{"id":"T25","span":{"begin":2012,"end":2028},"obj":"Body_part"},{"id":"T26","span":{"begin":2183,"end":2187},"obj":"Body_part"},{"id":"T27","span":{"begin":2451,"end":2468},"obj":"Body_part"},{"id":"T28","span":{"begin":2983,"end":2987},"obj":"Body_part"},{"id":"T29","span":{"begin":3137,"end":3141},"obj":"Body_part"},{"id":"T30","span":{"begin":3282,"end":3286},"obj":"Body_part"},{"id":"T31","span":{"begin":3432,"end":3436},"obj":"Body_part"},{"id":"T32","span":{"begin":3669,"end":3673},"obj":"Body_part"},{"id":"T33","span":{"begin":4145,"end":4149},"obj":"Body_part"}],"attributes":[{"id":"A23","pred":"uberon_id","subj":"T23","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"A24","pred":"uberon_id","subj":"T24","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"A25","pred":"uberon_id","subj":"T25","obj":"http://purl.obolibrary.org/obo/UBERON_0000175"},{"id":"A26","pred":"uberon_id","subj":"T26","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"A27","pred":"uberon_id","subj":"T27","obj":"http://purl.obolibrary.org/obo/UBERON_0000175"},{"id":"A28","pred":"uberon_id","subj":"T28","obj":"http://purl.obolibrary.org/obo/UBERON_3010752"},{"id":"A29","pred":"uberon_id","subj":"T29","obj":"http://purl.obolibrary.org/obo/UBERON_3010752"},{"id":"A30","pred":"uberon_id","subj":"T30","obj":"http://purl.obolibrary.org/obo/UBERON_3010752"},{"id":"A31","pred":"uberon_id","subj":"T31","obj":"http://purl.obolibrary.org/obo/UBERON_3010752"},{"id":"A32","pred":"uberon_id","subj":"T32","obj":"http://purl.obolibrary.org/obo/UBERON_3010752"},{"id":"A33","pred":"uberon_id","subj":"T33","obj":"http://purl.obolibrary.org/obo/UBERON_3010752"},{"subj":"T23","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T24","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T25","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T26","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T27","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T28","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T29","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T30","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T31","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T32","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T33","pred":"source","obj":"LitCovid-PD-UBERON"}]},{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T40","span":{"begin":42,"end":50},"obj":"Disease"},{"id":"T41","span":{"begin":1161,"end":1169},"obj":"Disease"},{"id":"T42","span":{"begin":2065,"end":2080},"obj":"Disease"},{"id":"T43","span":{"begin":2486,"end":2501},"obj":"Disease"},{"id":"T44","span":{"begin":2786,"end":2794},"obj":"Disease"},{"id":"T45","span":{"begin":2795,"end":2804},"obj":"Disease"}],"attributes":[{"id":"A40","pred":"mondo_id","subj":"T40","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A41","pred":"mondo_id","subj":"T41","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A42","pred":"mondo_id","subj":"T42","obj":"http://purl.obolibrary.org/obo/MONDO_0005833"},{"id":"A43","pred":"mondo_id","subj":"T43","obj":"http://purl.obolibrary.org/obo/MONDO_0005833"},{"id":"A44","pred":"mondo_id","subj":"T44","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A45","pred":"mondo_id","subj":"T45","obj":"http://purl.obolibrary.org/obo/MONDO_0005249"},{"subj":"T40","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T41","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T42","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T43","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T44","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T45","pred":"source","obj":"LitCovid-PD-MONDO"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T76","span":{"begin":630,"end":631},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T77","span":{"begin":692,"end":693},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T78","span":{"begin":784,"end":785},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T79","span":{"begin":1059,"end":1063},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T80","span":{"begin":1059,"end":1063},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T81","span":{"begin":1123,"end":1127},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T82","span":{"begin":1123,"end":1127},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T83","span":{"begin":1316,"end":1318},"obj":"http://purl.obolibrary.org/obo/CLO_0053733"},{"id":"T84","span":{"begin":2012,"end":2028},"obj":"http://purl.obolibrary.org/obo/UBERON_0000175"},{"id":"T85","span":{"begin":2183,"end":2187},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T86","span":{"begin":2183,"end":2187},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T87","span":{"begin":2312,"end":2314},"obj":"http://purl.obolibrary.org/obo/CLO_0053733"},{"id":"T88","span":{"begin":2330,"end":2332},"obj":"http://purl.obolibrary.org/obo/CLO_0053733"},{"id":"T89","span":{"begin":2451,"end":2468},"obj":"http://purl.obolibrary.org/obo/UBERON_0000175"},{"id":"T90","span":{"begin":2813,"end":2817},"obj":"http://purl.obolibrary.org/obo/CLO_0001599"},{"id":"T91","span":{"begin":2850,"end":2851},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T92","span":{"begin":2959,"end":2960},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T93","span":{"begin":3033,"end":3036},"obj":"http://purl.obolibrary.org/obo/CLO_0002755"},{"id":"T94","span":{"begin":3055,"end":3056},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T95","span":{"begin":3093,"end":3098},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T96","span":{"begin":3338,"end":3340},"obj":"http://purl.obolibrary.org/obo/CLO_0053733"},{"id":"T97","span":{"begin":3481,"end":3485},"obj":"http://purl.obolibrary.org/obo/CLO_0001568"},{"id":"T98","span":{"begin":3516,"end":3517},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T99","span":{"begin":3618,"end":3621},"obj":"http://purl.obolibrary.org/obo/CLO_0051456"},{"id":"T100","span":{"begin":3964,"end":3966},"obj":"http://purl.obolibrary.org/obo/CLO_0053733"}],"attributes":[{"subj":"T76","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T77","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T78","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T79","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T80","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T81","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T82","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T83","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T84","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T85","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T86","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T87","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T88","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T89","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T90","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T91","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T92","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T93","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T94","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T95","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T96","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T97","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T98","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T99","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T100","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T29","span":{"begin":2212,"end":2214},"obj":"Chemical"}],"attributes":[{"id":"A29","pred":"chebi_id","subj":"T29","obj":"http://purl.obolibrary.org/obo/CHEBI_74807"},{"subj":"T29","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-PD-HP","denotations":[{"id":"T35","span":{"begin":1351,"end":1370},"obj":"Phenotype"},{"id":"T36","span":{"begin":2012,"end":2028},"obj":"Phenotype"},{"id":"T37","span":{"begin":2065,"end":2080},"obj":"Phenotype"},{"id":"T38","span":{"begin":2451,"end":2468},"obj":"Phenotype"},{"id":"T39","span":{"begin":2486,"end":2501},"obj":"Phenotype"},{"id":"T40","span":{"begin":2795,"end":2804},"obj":"Phenotype"},{"id":"T41","span":{"begin":2890,"end":2895},"obj":"Phenotype"},{"id":"T42","span":{"begin":2897,"end":2902},"obj":"Phenotype"},{"id":"T43","span":{"begin":2908,"end":2921},"obj":"Phenotype"},{"id":"T44","span":{"begin":3556,"end":3561},"obj":"Phenotype"},{"id":"T45","span":{"begin":3566,"end":3571},"obj":"Phenotype"},{"id":"T46","span":{"begin":4158,"end":4168},"obj":"Phenotype"}],"attributes":[{"id":"A35","pred":"hp_id","subj":"T35","obj":"http://purl.obolibrary.org/obo/HP_0031457"},{"id":"A36","pred":"hp_id","subj":"T36","obj":"http://purl.obolibrary.org/obo/HP_0002202"},{"id":"A37","pred":"hp_id","subj":"T37","obj":"http://purl.obolibrary.org/obo/HP_0002716"},{"id":"A38","pred":"hp_id","subj":"T38","obj":"http://purl.obolibrary.org/obo/HP_0002202"},{"id":"A39","pred":"hp_id","subj":"T39","obj":"http://purl.obolibrary.org/obo/HP_0002716"},{"id":"A40","pred":"hp_id","subj":"T40","obj":"http://purl.obolibrary.org/obo/HP_0002090"},{"id":"A41","pred":"hp_id","subj":"T41","obj":"http://purl.obolibrary.org/obo/HP_0001945"},{"id":"A42","pred":"hp_id","subj":"T42","obj":"http://purl.obolibrary.org/obo/HP_0012735"},{"id":"A43","pred":"hp_id","subj":"T43","obj":"http://purl.obolibrary.org/obo/HP_0003419"},{"id":"A44","pred":"hp_id","subj":"T44","obj":"http://purl.obolibrary.org/obo/HP_0001945"},{"id":"A45","pred":"hp_id","subj":"T45","obj":"http://purl.obolibrary.org/obo/HP_0012735"},{"id":"A46","pred":"hp_id","subj":"T46","obj":"http://purl.obolibrary.org/obo/HP_0032983"},{"subj":"T35","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T36","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T37","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T38","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T39","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T40","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T41","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T42","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T43","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T44","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T45","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T46","pred":"source","obj":"LitCovid-PD-HP"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T140","span":{"begin":0,"end":50},"obj":"Sentence"},{"id":"T141","span":{"begin":51,"end":112},"obj":"Sentence"},{"id":"T142","span":{"begin":113,"end":236},"obj":"Sentence"},{"id":"T143","span":{"begin":237,"end":363},"obj":"Sentence"},{"id":"T144","span":{"begin":364,"end":629},"obj":"Sentence"},{"id":"T145","span":{"begin":630,"end":959},"obj":"Sentence"},{"id":"T146","span":{"begin":960,"end":1079},"obj":"Sentence"},{"id":"T147","span":{"begin":1080,"end":1204},"obj":"Sentence"},{"id":"T148","span":{"begin":1205,"end":1255},"obj":"Sentence"},{"id":"T149","span":{"begin":1256,"end":1350},"obj":"Sentence"},{"id":"T150","span":{"begin":1351,"end":1370},"obj":"Sentence"},{"id":"T151","span":{"begin":1371,"end":1434},"obj":"Sentence"},{"id":"T152","span":{"begin":1435,"end":1516},"obj":"Sentence"},{"id":"T153","span":{"begin":1517,"end":1593},"obj":"Sentence"},{"id":"T154","span":{"begin":1594,"end":1664},"obj":"Sentence"},{"id":"T155","span":{"begin":1665,"end":1749},"obj":"Sentence"},{"id":"T156","span":{"begin":1750,"end":1854},"obj":"Sentence"},{"id":"T157","span":{"begin":1855,"end":1917},"obj":"Sentence"},{"id":"T158","span":{"begin":1918,"end":1932},"obj":"Sentence"},{"id":"T159","span":{"begin":1933,"end":2009},"obj":"Sentence"},{"id":"T160","span":{"begin":2010,"end":2062},"obj":"Sentence"},{"id":"T161","span":{"begin":2063,"end":2114},"obj":"Sentence"},{"id":"T162","span":{"begin":2115,"end":2176},"obj":"Sentence"},{"id":"T163","span":{"begin":2177,"end":2202},"obj":"Sentence"},{"id":"T164","span":{"begin":2203,"end":2271},"obj":"Sentence"},{"id":"T165","span":{"begin":2272,"end":2337},"obj":"Sentence"},{"id":"T166","span":{"begin":2338,"end":2376},"obj":"Sentence"},{"id":"T167","span":{"begin":2377,"end":2425},"obj":"Sentence"},{"id":"T168","span":{"begin":2426,"end":2530},"obj":"Sentence"},{"id":"T169","span":{"begin":2531,"end":2714},"obj":"Sentence"},{"id":"T170","span":{"begin":2715,"end":2805},"obj":"Sentence"},{"id":"T171","span":{"begin":2806,"end":3001},"obj":"Sentence"},{"id":"T172","span":{"begin":3002,"end":3099},"obj":"Sentence"},{"id":"T173","span":{"begin":3100,"end":3147},"obj":"Sentence"},{"id":"T174","span":{"begin":3148,"end":3244},"obj":"Sentence"},{"id":"T175","span":{"begin":3245,"end":3292},"obj":"Sentence"},{"id":"T176","span":{"begin":3293,"end":3394},"obj":"Sentence"},{"id":"T177","span":{"begin":3395,"end":3442},"obj":"Sentence"},{"id":"T178","span":{"begin":3443,"end":3473},"obj":"Sentence"},{"id":"T179","span":{"begin":3474,"end":3697},"obj":"Sentence"},{"id":"T180","span":{"begin":3698,"end":3807},"obj":"Sentence"},{"id":"T181","span":{"begin":3808,"end":3908},"obj":"Sentence"},{"id":"T182","span":{"begin":3909,"end":4041},"obj":"Sentence"},{"id":"T183","span":{"begin":4042,"end":4183},"obj":"Sentence"},{"id":"T184","span":{"begin":4184,"end":4221},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T140","pred":"source","obj":"LitCovid-sentences"},{"subj":"T141","pred":"source","obj":"LitCovid-sentences"},{"subj":"T142","pred":"source","obj":"LitCovid-sentences"},{"subj":"T143","pred":"source","obj":"LitCovid-sentences"},{"subj":"T144","pred":"source","obj":"LitCovid-sentences"},{"subj":"T145","pred":"source","obj":"LitCovid-sentences"},{"subj":"T146","pred":"source","obj":"LitCovid-sentences"},{"subj":"T147","pred":"source","obj":"LitCovid-sentences"},{"subj":"T148","pred":"source","obj":"LitCovid-sentences"},{"subj":"T149","pred":"source","obj":"LitCovid-sentences"},{"subj":"T150","pred":"source","obj":"LitCovid-sentences"},{"subj":"T151","pred":"source","obj":"LitCovid-sentences"},{"subj":"T152","pred":"source","obj":"LitCovid-sentences"},{"subj":"T153","pred":"source","obj":"LitCovid-sentences"},{"subj":"T154","pred":"source","obj":"LitCovid-sentences"},{"subj":"T155","pred":"source","obj":"LitCovid-sentences"},{"subj":"T156","pred":"source","obj":"LitCovid-sentences"},{"subj":"T157","pred":"source","obj":"LitCovid-sentences"},{"subj":"T158","pred":"source","obj":"LitCovid-sentences"},{"subj":"T159","pred":"source","obj":"LitCovid-sentences"},{"subj":"T160","pred":"source","obj":"LitCovid-sentences"},{"subj":"T161","pred":"source","obj":"LitCovid-sentences"},{"subj":"T162","pred":"source","obj":"LitCovid-sentences"},{"subj":"T163","pred":"source","obj":"LitCovid-sentences"},{"subj":"T164","pred":"source","obj":"LitCovid-sentences"},{"subj":"T165","pred":"source","obj":"LitCovid-sentences"},{"subj":"T166","pred":"source","obj":"LitCovid-sentences"},{"subj":"T167","pred":"source","obj":"LitCovid-sentences"},{"subj":"T168","pred":"source","obj":"LitCovid-sentences"},{"subj":"T169","pred":"source","obj":"LitCovid-sentences"},{"subj":"T170","pred":"source","obj":"LitCovid-sentences"},{"subj":"T171","pred":"source","obj":"LitCovid-sentences"},{"subj":"T172","pred":"source","obj":"LitCovid-sentences"},{"subj":"T173","pred":"source","obj":"LitCovid-sentences"},{"subj":"T174","pred":"source","obj":"LitCovid-sentences"},{"subj":"T175","pred":"source","obj":"LitCovid-sentences"},{"subj":"T176","pred":"source","obj":"LitCovid-sentences"},{"subj":"T177","pred":"source","obj":"LitCovid-sentences"},{"subj":"T178","pred":"source","obj":"LitCovid-sentences"},{"subj":"T179","pred":"source","obj":"LitCovid-sentences"},{"subj":"T180","pred":"source","obj":"LitCovid-sentences"},{"subj":"T181","pred":"source","obj":"LitCovid-sentences"},{"subj":"T182","pred":"source","obj":"LitCovid-sentences"},{"subj":"T183","pred":"source","obj":"LitCovid-sentences"},{"subj":"T184","pred":"source","obj":"LitCovid-sentences"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PubTator","color":"#93ec93","default":true},{"id":"LitCovid-PD-FMA-UBERON","color":"#ec93ac"},{"id":"LitCovid-PD-UBERON","color":"#93c6ec"},{"id":"LitCovid-PD-MONDO","color":"#e0ec93"},{"id":"LitCovid-PD-CLO","color":"#de93ec"},{"id":"LitCovid-PD-CHEBI","color":"#93ecc4"},{"id":"LitCovid-PD-HP","color":"#ecaa93"},{"id":"LitCovid-sentences","color":"#9396ec"}]}]}}