PMC:7152911 / 44536-46419 JSONTXT

Annnotations TAB JSON ListView MergeView

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7152911","sourcedb":"PMC","sourceid":"7152911","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7152911","text":"2.1.4 Electrode form factor and patterning\nAs shown in Table 1, Au electrodes of various size and form factor have been used for pathogen detection. The use of complex masks and programmable tool paths with lithographic and 3D printing processes, respectively, also enable the fabrication of complex electrode geometries (Cesewski et al. 2018; Xu et al. 2017). In addition to complex form factor, lithographic processes, 3D printing processes, and assembly operations also enable the fabrication of electrode arrays through electrode patterning (Hintsche et al. 1994). Electrode arrays, including interdigitated microelectrodes and other patterned electrodes, have been developed in an attempt to enhance the sensitivity and multiplexing capability of biosensors. Interdigitated array microelectrodes (IDAMs) consist of alternating, parallel-electrode fingers organized in an interdigitated pattern. IDAMs have been shown to exhibit rapid response and high signal-to-noise ratio (Varshney and Li, 2009). As shown in Table 1, Au interdigitated microelectrode arrays are one of the most common electrode configurations for pathogen detection. For example, Dastider et al. usedinterdigitated Au microelectrode arrays for detection of S. typhimurium via EIS (see Fig. 4a) (Dastider et al. 2015). Ceramic electrodes, such as ITO, with interdigitated array designs have also been examined for the detection of S. typhimurium (Yang and Li, 2006). Mannoor et al. also examined interdigitated carbon-based electrodes for pathogen detection (Mannoor et al. 2012). The aforementioned emerging manufacturing processes are also used to construct electrode arrays that exhibit geometries other than interdigitated designs for electrochemical sensing applications. For example, Yang et al. used aerosol jet additive manufacturing to fabricate silver (Ag) microelectrode arrays (Yang et al. 2016a).","divisions":[{"label":"label","span":{"begin":0,"end":5}},{"label":"title","span":{"begin":7,"end":43}}],"tracks":[{"project":"LitCovid-PubTator","denotations":[{"id":"1276","span":{"begin":1232,"end":1246},"obj":"Species"},{"id":"1277","span":{"begin":1405,"end":1419},"obj":"Species"},{"id":"1278","span":{"begin":65,"end":67},"obj":"Chemical"},{"id":"1279","span":{"begin":1026,"end":1028},"obj":"Chemical"},{"id":"1280","span":{"begin":1190,"end":1192},"obj":"Chemical"},{"id":"1281","span":{"begin":1321,"end":1324},"obj":"Chemical"},{"id":"1282","span":{"begin":1485,"end":1491},"obj":"Chemical"},{"id":"1283","span":{"begin":1829,"end":1835},"obj":"Chemical"}],"attributes":[{"id":"A1276","pred":"tao:has_database_id","subj":"1276","obj":"Tax:90371"},{"id":"A1277","pred":"tao:has_database_id","subj":"1277","obj":"Tax:90371"},{"id":"A1278","pred":"tao:has_database_id","subj":"1278","obj":"MESH:D006046"},{"id":"A1279","pred":"tao:has_database_id","subj":"1279","obj":"MESH:D006046"},{"id":"A1280","pred":"tao:has_database_id","subj":"1280","obj":"MESH:D006046"},{"id":"A1281","pred":"tao:has_database_id","subj":"1281","obj":"MESH:C109984"},{"id":"A1282","pred":"tao:has_database_id","subj":"1282","obj":"MESH:D002244"},{"id":"A1283","pred":"tao:has_database_id","subj":"1283","obj":"MESH:D012834"},{"subj":"1276","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1277","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1278","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1279","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1280","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1281","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1282","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1283","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T110","span":{"begin":853,"end":860},"obj":"Body_part"},{"id":"T111","span":{"begin":1837,"end":1839},"obj":"Body_part"}],"attributes":[{"id":"A110","pred":"fma_id","subj":"T110","obj":"http://purl.org/sig/ont/fma/fma9666"},{"id":"A111","pred":"fma_id","subj":"T111","obj":"http://purl.org/sig/ont/fma/fma61898"},{"subj":"T110","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T111","pred":"source","obj":"LitCovid-PD-FMA-UBERON"}]},{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T7","span":{"begin":853,"end":860},"obj":"Body_part"}],"attributes":[{"id":"A7","pred":"uberon_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/UBERON_0002389"},{"subj":"T7","pred":"source","obj":"LitCovid-PD-UBERON"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T329","span":{"begin":339,"end":343},"obj":"http://purl.obolibrary.org/obo/CLO_0001185"},{"id":"T330","span":{"begin":861,"end":873},"obj":"http://purl.obolibrary.org/obo/OBI_0000245"},{"id":"T331","span":{"begin":958,"end":964},"obj":"http://purl.obolibrary.org/obo/SO_0000418"},{"id":"T332","span":{"begin":994,"end":996},"obj":"http://purl.obolibrary.org/obo/CLO_0001022"},{"id":"T333","span":{"begin":994,"end":996},"obj":"http://purl.obolibrary.org/obo/CLO_0007314"},{"id":"T334","span":{"begin":1430,"end":1432},"obj":"http://purl.obolibrary.org/obo/CLO_0001022"},{"id":"T335","span":{"begin":1430,"end":1432},"obj":"http://purl.obolibrary.org/obo/CLO_0007314"}],"attributes":[{"subj":"T329","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T330","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T331","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T332","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T333","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T334","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T335","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T861","span":{"begin":65,"end":67},"obj":"Chemical"},{"id":"T862","span":{"begin":994,"end":996},"obj":"Chemical"},{"id":"T863","span":{"begin":1026,"end":1028},"obj":"Chemical"},{"id":"T864","span":{"begin":1190,"end":1192},"obj":"Chemical"},{"id":"T865","span":{"begin":1251,"end":1254},"obj":"Chemical"},{"id":"T866","span":{"begin":1430,"end":1432},"obj":"Chemical"},{"id":"T867","span":{"begin":1485,"end":1491},"obj":"Chemical"},{"id":"T869","span":{"begin":1829,"end":1835},"obj":"Chemical"},{"id":"T871","span":{"begin":1837,"end":1839},"obj":"Chemical"}],"attributes":[{"id":"A861","pred":"chebi_id","subj":"T861","obj":"http://purl.obolibrary.org/obo/CHEBI_29287"},{"id":"A862","pred":"chebi_id","subj":"T862","obj":"http://purl.obolibrary.org/obo/CHEBI_30145"},{"id":"A863","pred":"chebi_id","subj":"T863","obj":"http://purl.obolibrary.org/obo/CHEBI_29287"},{"id":"A864","pred":"chebi_id","subj":"T864","obj":"http://purl.obolibrary.org/obo/CHEBI_29287"},{"id":"A865","pred":"chebi_id","subj":"T865","obj":"http://purl.obolibrary.org/obo/CHEBI_73498"},{"id":"A866","pred":"chebi_id","subj":"T866","obj":"http://purl.obolibrary.org/obo/CHEBI_30145"},{"id":"A867","pred":"chebi_id","subj":"T867","obj":"http://purl.obolibrary.org/obo/CHEBI_27594"},{"id":"A868","pred":"chebi_id","subj":"T867","obj":"http://purl.obolibrary.org/obo/CHEBI_33415"},{"id":"A869","pred":"chebi_id","subj":"T869","obj":"http://purl.obolibrary.org/obo/CHEBI_30512"},{"id":"A870","pred":"chebi_id","subj":"T869","obj":"http://purl.obolibrary.org/obo/CHEBI_9141"},{"id":"A871","pred":"chebi_id","subj":"T871","obj":"http://purl.obolibrary.org/obo/CHEBI_30512"},{"id":"A872","pred":"chebi_id","subj":"T871","obj":"http://purl.obolibrary.org/obo/CHEBI_9141"},{"subj":"T861","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T862","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T863","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T864","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T865","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T866","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T867","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T869","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T871","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T346","span":{"begin":0,"end":43},"obj":"Sentence"},{"id":"T347","span":{"begin":44,"end":149},"obj":"Sentence"},{"id":"T348","span":{"begin":150,"end":338},"obj":"Sentence"},{"id":"T349","span":{"begin":339,"end":354},"obj":"Sentence"},{"id":"T350","span":{"begin":355,"end":361},"obj":"Sentence"},{"id":"T351","span":{"begin":362,"end":562},"obj":"Sentence"},{"id":"T352","span":{"begin":563,"end":569},"obj":"Sentence"},{"id":"T353","span":{"begin":570,"end":764},"obj":"Sentence"},{"id":"T354","span":{"begin":765,"end":900},"obj":"Sentence"},{"id":"T355","span":{"begin":901,"end":1004},"obj":"Sentence"},{"id":"T356","span":{"begin":1005,"end":1141},"obj":"Sentence"},{"id":"T357","span":{"begin":1142,"end":1285},"obj":"Sentence"},{"id":"T358","span":{"begin":1286,"end":1292},"obj":"Sentence"},{"id":"T359","span":{"begin":1293,"end":1440},"obj":"Sentence"},{"id":"T360","span":{"begin":1441,"end":1547},"obj":"Sentence"},{"id":"T361","span":{"begin":1548,"end":1554},"obj":"Sentence"},{"id":"T362","span":{"begin":1555,"end":1750},"obj":"Sentence"},{"id":"T363","span":{"begin":1751,"end":1875},"obj":"Sentence"},{"id":"T364","span":{"begin":1876,"end":1883},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T346","pred":"source","obj":"LitCovid-sentences"},{"subj":"T347","pred":"source","obj":"LitCovid-sentences"},{"subj":"T348","pred":"source","obj":"LitCovid-sentences"},{"subj":"T349","pred":"source","obj":"LitCovid-sentences"},{"subj":"T350","pred":"source","obj":"LitCovid-sentences"},{"subj":"T351","pred":"source","obj":"LitCovid-sentences"},{"subj":"T352","pred":"source","obj":"LitCovid-sentences"},{"subj":"T353","pred":"source","obj":"LitCovid-sentences"},{"subj":"T354","pred":"source","obj":"LitCovid-sentences"},{"subj":"T355","pred":"source","obj":"LitCovid-sentences"},{"subj":"T356","pred":"source","obj":"LitCovid-sentences"},{"subj":"T357","pred":"source","obj":"LitCovid-sentences"},{"subj":"T358","pred":"source","obj":"LitCovid-sentences"},{"subj":"T359","pred":"source","obj":"LitCovid-sentences"},{"subj":"T360","pred":"source","obj":"LitCovid-sentences"},{"subj":"T361","pred":"source","obj":"LitCovid-sentences"},{"subj":"T362","pred":"source","obj":"LitCovid-sentences"},{"subj":"T363","pred":"source","obj":"LitCovid-sentences"},{"subj":"T364","pred":"source","obj":"LitCovid-sentences"}]},{"project":"2_test","denotations":[{"id":"32364936-29897358-7713031","span":{"begin":339,"end":343},"obj":"29897358"},{"id":"32364936-19041235-7713032","span":{"begin":998,"end":1002},"obj":"19041235"},{"id":"32364936-15936099-7713033","span":{"begin":1434,"end":1438},"obj":"15936099"},{"id":"32364936-22453836-7713034","span":{"begin":1548,"end":1552},"obj":"22453836"}],"attributes":[{"subj":"32364936-29897358-7713031","pred":"source","obj":"2_test"},{"subj":"32364936-19041235-7713032","pred":"source","obj":"2_test"},{"subj":"32364936-15936099-7713033","pred":"source","obj":"2_test"},{"subj":"32364936-22453836-7713034","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PubTator","color":"#eccf93","default":true},{"id":"LitCovid-PD-FMA-UBERON","color":"#b593ec"},{"id":"LitCovid-PD-UBERON","color":"#93ec9b"},{"id":"LitCovid-PD-CLO","color":"#ec93a4"},{"id":"LitCovid-PD-CHEBI","color":"#93beec"},{"id":"LitCovid-sentences","color":"#d8ec93"},{"id":"2_test","color":"#e593ec"}]}]}}