PMC:7152526 / 13592-14388 JSONTXT

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Other studies about viral kinetics of COVID-19 show naturally reducing viral titers after 7–10 days from onset in most patients.1617 However, Liu and colleagues reported that severe patients requiring intensive care unit admission due to COVID-19 had high viral load for a longer period than in mild patients.16 Both our cases presented severe ARDS and the viral loads were in increasing trend at the time of plasma infusion regardless of the date of 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