PMC:7143804 / 9343-10920
Annnotations
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 95 | 148-155 | Chemical | denotes | polymer | MESH:D011108 |
| 96 | 674-679 | Chemical | denotes | metal | MESH:D008670 |
| 97 | 711-716 | Chemical | denotes | metal | MESH:D008670 |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T21 | 162-165 | Body_part | denotes | DNA | http://purl.org/sig/ont/fma/fma74412 |
| T22 | 948-951 | Body_part | denotes | DNA | http://purl.org/sig/ont/fma/fma74412 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T19 | 277-306 | Disease | denotes | Sexually Transmitted Diseases | http://purl.obolibrary.org/obo/MONDO_0021681 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T68 | 134-135 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T69 | 258-270 | http://purl.obolibrary.org/obo/OBI_0000245 | denotes | Organization |
| T70 | 354-361 | http://purl.obolibrary.org/obo/OBI_0000968 | denotes | Devices |
| T71 | 385-386 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T72 | 570-571 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T73 | 572-578 | http://purl.obolibrary.org/obo/OBI_0000968 | denotes | device |
| T74 | 629-636 | http://purl.obolibrary.org/obo/CLO_0009985 | denotes | focuses |
| T75 | 989-990 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T76 | 1230-1236 | http://purl.obolibrary.org/obo/OBI_0000968 | denotes | device |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T56 | 148-155 | Chemical | denotes | polymer | http://purl.obolibrary.org/obo/CHEBI_33839|http://purl.obolibrary.org/obo/CHEBI_60027 |
| T58 | 162-165 | Chemical | denotes | DNA | http://purl.obolibrary.org/obo/CHEBI_16991 |
| T59 | 763-766 | Chemical | denotes | HDA | http://purl.obolibrary.org/obo/CHEBI_17314 |
| T60 | 865-868 | Chemical | denotes | MDA | http://purl.obolibrary.org/obo/CHEBI_566274 |
| T61 | 948-951 | Chemical | denotes | DNA | http://purl.obolibrary.org/obo/CHEBI_16991 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T6 | 162-179 | http://purl.obolibrary.org/obo/GO_0006277 | denotes | DNA amplification |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T81 | 0-353 | Sentence | denotes | The work presented at the 4th Microfluidic Handling Systems conference and which is extended in this paper aims at the development of a disposable, polymer-based DNA amplification lab-on-chip system with integrated resistive heater based on the World Health Organization (WHO) Sexually Transmitted Diseases Diagnostics Initiative (SDI) ASSURED criteria. |
| T82 | 354-541 | Sentence | denotes | Devices which are ASSURED are (A) affordable, (S) sensitive, (S) specific, (U) user-friendly, (R) robust and rapid, (E) equipment-free, and (D) deliverable to those who need them [20,49]. |
| T83 | 542-617 | Sentence | denotes | The first step towards such a device is the development of the chip itself. |
| T84 | 618-717 | Sentence | denotes | This paper focuses on the choice of substrate material, metal deposition method, and type of metal. |
| T85 | 718-875 | Sentence | denotes | Although, it is mentioned above that PCR and HDA are sequence specific, the reaction chosen is the isothermal multiple displacement amplification (MDA) [50]. |
| T86 | 876-1154 | Sentence | denotes | This reaction is more straightforward [51], as it amplifies any present DNA, and is therefore better suitable as a proof-of-principle amplification reaction to show the functioning of the integrated heater and the biocompatibility of the substrate after the fabrication process. |
| T87 | 1155-1294 | Sentence | denotes | The use of an isothermal amplification technique also simplifies the final device and lowers its footprint, as there are no pumps required. |
| T88 | 1295-1450 | Sentence | denotes | In this research, external analysis methods are used which do not contribute to the WHO-SDI ASSURED criteria due to their bulkiness, costs, and difficulty. |
| T89 | 1451-1577 | Sentence | denotes | However, suggestions and comments on the integration of low-cost detection methods, which are ASSURED, are given in Section 5. |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32106462-22704369-69893309 | 534-536 | 22704369 | denotes | 20 |
| 32106462-16786504-69893310 | 871-873 | 16786504 | denotes | 50 |