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PMC:7143804 / 30619-33004 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
213 1069-1071 Chemical denotes N2
214 1222-1233 Chemical denotes cyclohexane MESH:C506365
215 1398-1408 Chemical denotes norbornene MESH:C046060
216 1434-1440 Chemical denotes ethene MESH:C036216
217 1455-1465 Chemical denotes norbornene MESH:C046060
218 1500-1518 Chemical denotes cyclic hydrocarbon MESH:D006844
219 1618-1629 Chemical denotes cyclohexane MESH:C506365

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T50 500-502 Body_part denotes V2 http://purl.org/sig/ont/fma/fma13443|http://purl.org/sig/ont/fma/fma68615

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T31 686-690 Disease denotes RRMS http://purl.obolibrary.org/obo/MONDO_0005314
T32 756-760 Disease denotes RRMS http://purl.obolibrary.org/obo/MONDO_0005314
T33 958-962 Disease denotes RRMS http://purl.obolibrary.org/obo/MONDO_0005314

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T206 318-319 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T207 438-439 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T208 684-685 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T209 874-875 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T210 1784-1785 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T211 1844-1846 http://purl.obolibrary.org/obo/CLO_0008149 denotes NE
T212 1912-1913 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T213 2065-2068 http://purl.obolibrary.org/obo/CLO_0051582 denotes has

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T193 84-87 Chemical denotes COC http://purl.obolibrary.org/obo/CHEBI_53310
T194 356-364 Chemical denotes electron http://purl.obolibrary.org/obo/CHEBI_10545
T195 676-679 Chemical denotes COC http://purl.obolibrary.org/obo/CHEBI_53310
T196 915-918 Chemical denotes COC http://purl.obolibrary.org/obo/CHEBI_53310
T197 993-996 Chemical denotes COC http://purl.obolibrary.org/obo/CHEBI_53310
T198 1069-1071 Chemical denotes N2 http://purl.obolibrary.org/obo/CHEBI_17997
T199 1174-1177 Chemical denotes COC http://purl.obolibrary.org/obo/CHEBI_53310
T200 1222-1233 Chemical denotes cyclohexane http://purl.obolibrary.org/obo/CHEBI_29005
T201 1303-1313 Chemical denotes copolymers http://purl.obolibrary.org/obo/CHEBI_53310|http://purl.obolibrary.org/obo/CHEBI_60804
T203 1398-1408 Chemical denotes norbornene http://purl.obolibrary.org/obo/CHEBI_52286
T204 1434-1440 Chemical denotes ethene http://purl.obolibrary.org/obo/CHEBI_18153
T205 1455-1465 Chemical denotes norbornene http://purl.obolibrary.org/obo/CHEBI_52286
T206 1500-1518 Chemical denotes cyclic hydrocarbon http://purl.obolibrary.org/obo/CHEBI_33663
T207 1507-1518 Chemical denotes hydrocarbon http://purl.obolibrary.org/obo/CHEBI_24632
T208 1597-1611 Chemical denotes polar solvents http://purl.obolibrary.org/obo/CHEBI_48354
T209 1603-1611 Chemical denotes solvents http://purl.obolibrary.org/obo/CHEBI_46787
T210 1618-1629 Chemical denotes cyclohexane http://purl.obolibrary.org/obo/CHEBI_29005
T211 1830-1832 Chemical denotes Co http://purl.obolibrary.org/obo/CHEBI_27638
T212 1844-1846 Chemical denotes NE http://purl.obolibrary.org/obo/CHEBI_73824
T213 2061-2064 Chemical denotes dye http://purl.obolibrary.org/obo/CHEBI_37958

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T236 0-32 Sentence denotes Milling and Optical Transparency
T237 33-127 Sentence denotes The milling increased the surface roughness of the COC plates also increases the surface area.
T238 128-267 Sentence denotes Inhibition of the amplification can be caused by large surface areas as the used chemicals have more surface to have interaction with [44].
T239 268-606 Sentence denotes The created surface roughness is visualized using a FEI Sirion high resolution scanning electron microscope (HR-SEM) (FEI Company, Hillsboro, OR, USA) and measured using a Bruker Icon Dimension AFM in tapping mode with Bruker Tespa-V2 cantilevers (Bruker Nano Surfaces, Santa Barbara, CA, USA) and Gwyddion 2.52 open source freeware [62].
T240 607-641 Sentence denotes The results are shown in Figure 8.
T241 642-701 Sentence denotes The surface roughness of pristine COC had a RRMS of 3.5 nm.
T242 702-774 Sentence denotes This increased two orders of magnitude after milling (RRMS of 310.1 nm).
T243 775-974 Sentence denotes With the reported surface treatment [44,59] we were capable of decreasing the surface roughness to a value even lower than that of pristine COC and the lowest reported in literature (RRMS of 0.9 nm).
T244 975-1186 Sentence denotes For this grade of COC (TOPAS 6017) it worked the best to do four short exposures of 5 s, with N2 blow drying after each exposure, instead of one longer exposure, as is more common in other grades of COC [44,59].
T245 1187-1336 Sentence denotes The difference in duration for the cyclohexane vapor post-treatment can be explained by the different ratios of the copolymers present in each grade.
T246 1337-1450 Sentence denotes As the grade number increase, the ratio changes towards more norbornene monomers and less linear ethene monomers.
T247 1451-1638 Sentence denotes The norbornene is more apolar due to the bridged cyclic hydrocarbon present in its molecular structure and therefore, will dissolve faster in non-polar solvents, like cyclohexane (vapor).
T248 1639-1720 Sentence denotes Lowering the surface roughness also increased the optical transmittance fivefold.
T249 1721-1821 Sentence denotes Transmittance measurements in the visible range are done using a Woollam M-2000UI ellipsometer (J.A.
T250 1822-1853 Sentence denotes Woollam Co., Lincoln, NE, USA).
T251 1854-1904 Sentence denotes The results can be seen in Figure 9 and Figure 10.
T252 1905-2144 Sentence denotes Having a high optical transparency in the visible range can be desired when in situ fluorescence detection will be implemented (e.g., EvaGreen fluorescence dye has an excitation wavelength of 500 nm and emission wavelength of 525 nm [63]).
T253 2145-2385 Sentence denotes However, as in situ fluorescence detection is not used yet in this system and can also be done through the transparent PCR plate sealing foil, no further effort is put into optimizing this procedure to get even better optical transmittance.