PMC:7128678 / 7442-7854 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"193","span":{"begin":22,"end":33},"obj":"Chemical"},{"id":"194","span":{"begin":44,"end":62},"obj":"Chemical"},{"id":"195","span":{"begin":64,"end":70},"obj":"Chemical"},{"id":"196","span":{"begin":86,"end":92},"obj":"Chemical"},{"id":"197","span":{"begin":98,"end":104},"obj":"Chemical"},{"id":"198","span":{"begin":129,"end":135},"obj":"Chemical"},{"id":"199","span":{"begin":139,"end":144},"obj":"Chemical"},{"id":"200","span":{"begin":197,"end":202},"obj":"Chemical"},{"id":"201","span":{"begin":222,"end":223},"obj":"Chemical"},{"id":"202","span":{"begin":273,"end":279},"obj":"Chemical"},{"id":"203","span":{"begin":288,"end":296},"obj":"Chemical"},{"id":"204","span":{"begin":304,"end":310},"obj":"Chemical"},{"id":"205","span":{"begin":317,"end":325},"obj":"Chemical"},{"id":"206","span":{"begin":355,"end":363},"obj":"Chemical"},{"id":"207","span":{"begin":380,"end":386},"obj":"Chemical"}],"attributes":[{"id":"A193","pred":"tao:has_database_id","subj":"193","obj":"MESH:D002738"},{"id":"A194","pred":"tao:has_database_id","subj":"194","obj":"MESH:D006886"},{"id":"A199","pred":"tao:has_database_id","subj":"199","obj":"MESH:D014867"},{"id":"A200","pred":"tao:has_database_id","subj":"200","obj":"MESH:D014867"},{"id":"A201","pred":"tao:has_database_id","subj":"201","obj":"MESH:D002244"},{"id":"A202","pred":"tao:has_database_id","subj":"202","obj":"MESH:D002244"},{"id":"A203","pred":"tao:has_database_id","subj":"203","obj":"MESH:D009584"},{"id":"A204","pred":"tao:has_database_id","subj":"204","obj":"MESH:D010100"},{"id":"A205","pred":"tao:has_database_id","subj":"205","obj":"MESH:D006859"},{"id":"A206","pred":"tao:has_database_id","subj":"206","obj":"MESH:D002713"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Chemical structure of chloroquine (CLQ) and hydroxychloroquine (CLQ-OH). (a) CLQ. (b) CLQ-OH. (c) CLQ-OH extended conformer. (d) CLQ-OH in water. (e) Typical condensed conformer of CLQ. (f) CLQ in water. The molecules in (c–f) are shown in either tube or sphere rendering (carbon, green; nitrogen, blue; oxygen, red; hydrogen, white). In (c) and (e), the chlorine atom of CLQ and CLQ-OH is indicated by an arrow."}

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T160","span":{"begin":22,"end":33},"obj":"CHEBI:3638;DG_10;CHEBI:3638"},{"id":"T161","span":{"begin":44,"end":62},"obj":"CHEBI:5801;DG_20;CHEBI:5801"},{"id":"T162","span":{"begin":139,"end":144},"obj":"CHEBI:15377;CHEBI:15377"},{"id":"T163","span":{"begin":197,"end":202},"obj":"CHEBI:15377;CHEBI:15377"},{"id":"T164","span":{"begin":208,"end":217},"obj":"CHEBI:36357;CHEBI:36357"},{"id":"T165","span":{"begin":355,"end":363},"obj":"CHEBI:33910;CHEBI:33910"},{"id":"T166","span":{"begin":364,"end":368},"obj":"CHEBI:33250;CHEBI:33250"}],"text":"Chemical structure of chloroquine (CLQ) and hydroxychloroquine (CLQ-OH). (a) CLQ. (b) CLQ-OH. (c) CLQ-OH extended conformer. (d) CLQ-OH in water. (e) Typical condensed conformer of CLQ. (f) CLQ in water. The molecules in (c–f) are shown in either tube or sphere rendering (carbon, green; nitrogen, blue; oxygen, red; hydrogen, white). In (c) and (e), the chlorine atom of CLQ and CLQ-OH is indicated by an arrow."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T3","span":{"begin":247,"end":251},"obj":"Body_part"}],"attributes":[{"id":"A3","pred":"uberon_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/UBERON_0000025"}],"text":"Chemical structure of chloroquine (CLQ) and hydroxychloroquine (CLQ-OH). (a) CLQ. (b) CLQ-OH. (c) CLQ-OH extended conformer. (d) CLQ-OH in water. (e) Typical condensed conformer of CLQ. (f) CLQ in water. The molecules in (c–f) are shown in either tube or sphere rendering (carbon, green; nitrogen, blue; oxygen, red; hydrogen, white). In (c) and (e), the chlorine atom of CLQ and CLQ-OH is indicated by an arrow."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T48","span":{"begin":74,"end":75},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T49","span":{"begin":83,"end":84},"obj":"http://purl.obolibrary.org/obo/CLO_0001021"},{"id":"T50","span":{"begin":247,"end":251},"obj":"http://purl.obolibrary.org/obo/UBERON_0000025"}],"text":"Chemical structure of chloroquine (CLQ) and hydroxychloroquine (CLQ-OH). (a) CLQ. (b) CLQ-OH. (c) CLQ-OH extended conformer. (d) CLQ-OH in water. (e) Typical condensed conformer of CLQ. (f) CLQ in water. The molecules in (c–f) are shown in either tube or sphere rendering (carbon, green; nitrogen, blue; oxygen, red; hydrogen, white). In (c) and (e), the chlorine atom of CLQ and CLQ-OH is indicated by an arrow."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T103","span":{"begin":22,"end":33},"obj":"Chemical"},{"id":"T104","span":{"begin":44,"end":62},"obj":"Chemical"},{"id":"T105","span":{"begin":139,"end":144},"obj":"Chemical"},{"id":"T106","span":{"begin":197,"end":202},"obj":"Chemical"},{"id":"T107","span":{"begin":208,"end":217},"obj":"Chemical"},{"id":"T108","span":{"begin":273,"end":279},"obj":"Chemical"},{"id":"T110","span":{"begin":288,"end":296},"obj":"Chemical"},{"id":"T111","span":{"begin":304,"end":310},"obj":"Chemical"},{"id":"T112","span":{"begin":317,"end":325},"obj":"Chemical"},{"id":"T113","span":{"begin":355,"end":368},"obj":"Chemical"},{"id":"T114","span":{"begin":355,"end":363},"obj":"Chemical"},{"id":"T115","span":{"begin":364,"end":368},"obj":"Chemical"}],"attributes":[{"id":"A103","pred":"chebi_id","subj":"T103","obj":"http://purl.obolibrary.org/obo/CHEBI_3638"},{"id":"A104","pred":"chebi_id","subj":"T104","obj":"http://purl.obolibrary.org/obo/CHEBI_5801"},{"id":"A105","pred":"chebi_id","subj":"T105","obj":"http://purl.obolibrary.org/obo/CHEBI_15377"},{"id":"A106","pred":"chebi_id","subj":"T106","obj":"http://purl.obolibrary.org/obo/CHEBI_15377"},{"id":"A107","pred":"chebi_id","subj":"T107","obj":"http://purl.obolibrary.org/obo/CHEBI_25367"},{"id":"A108","pred":"chebi_id","subj":"T108","obj":"http://purl.obolibrary.org/obo/CHEBI_27594"},{"id":"A109","pred":"chebi_id","subj":"T108","obj":"http://purl.obolibrary.org/obo/CHEBI_33415"},{"id":"A110","pred":"chebi_id","subj":"T110","obj":"http://purl.obolibrary.org/obo/CHEBI_25555"},{"id":"A111","pred":"chebi_id","subj":"T111","obj":"http://purl.obolibrary.org/obo/CHEBI_25805"},{"id":"A112","pred":"chebi_id","subj":"T112","obj":"http://purl.obolibrary.org/obo/CHEBI_49637"},{"id":"A113","pred":"chebi_id","subj":"T113","obj":"http://purl.obolibrary.org/obo/CHEBI_23116"},{"id":"A114","pred":"chebi_id","subj":"T114","obj":"http://purl.obolibrary.org/obo/CHEBI_29310"},{"id":"A115","pred":"chebi_id","subj":"T115","obj":"http://purl.obolibrary.org/obo/CHEBI_33250"}],"text":"Chemical structure of chloroquine (CLQ) and hydroxychloroquine (CLQ-OH). (a) CLQ. (b) CLQ-OH. (c) CLQ-OH extended conformer. (d) CLQ-OH in water. (e) Typical condensed conformer of CLQ. (f) CLQ in water. The molecules in (c–f) are shown in either tube or sphere rendering (carbon, green; nitrogen, blue; oxygen, red; hydrogen, white). In (c) and (e), the chlorine atom of CLQ and CLQ-OH is indicated by an arrow."}

{"project":"LitCovid-sentences","denotations":[{"id":"T59","span":{"begin":204,"end":334},"obj":"Sentence"},{"id":"T60","span":{"begin":335,"end":412},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Chemical structure of chloroquine (CLQ) and hydroxychloroquine (CLQ-OH). (a) CLQ. (b) CLQ-OH. (c) CLQ-OH extended conformer. (d) CLQ-OH in water. (e) Typical condensed conformer of CLQ. (f) CLQ in water. The molecules in (c–f) are shown in either tube or sphere rendering (carbon, green; nitrogen, blue; oxygen, red; hydrogen, white). In (c) and (e), the chlorine atom of CLQ and CLQ-OH is indicated by an arrow."}