PMC:7128678 / 571-1086 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7128678","sourcedb":"PMC","sourceid":"7128678","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7128678","text":"SARS-CoV-2) is responsible for a worldwide pandemic. Given the global health emergency, drug repositioning is the most reliable option to design an efficient therapy for infected patients without delay. The first step of the viral replication cycle [i.e. attachment to the surface of respiratory cells, mediated by the spike (S) viral protein] offers several potential therapeutic targets. The S protein uses the angiotension-converting enzyme-2 (ACE-2) receptor for entry, but also sialic acids linked to host cell","tracks":[{"project":"LitCovid-PubTator","denotations":[{"id":"48","span":{"begin":447,"end":452},"obj":"Gene"},{"id":"50","span":{"begin":319,"end":324},"obj":"Gene"},{"id":"54","span":{"begin":0,"end":10},"obj":"Species"},{"id":"55","span":{"begin":179,"end":187},"obj":"Species"},{"id":"60","span":{"begin":413,"end":425},"obj":"Chemical"},{"id":"61","span":{"begin":483,"end":495},"obj":"Chemical"},{"id":"72","span":{"begin":170,"end":178},"obj":"Disease"}],"attributes":[{"id":"A48","pred":"tao:has_database_id","subj":"48","obj":"Gene:59272"},{"id":"A50","pred":"tao:has_database_id","subj":"50","obj":"Gene:43740568"},{"id":"A54","pred":"tao:has_database_id","subj":"54","obj":"Tax:2697049"},{"id":"A55","pred":"tao:has_database_id","subj":"55","obj":"Tax:9606"},{"id":"A61","pred":"tao:has_database_id","subj":"61","obj":"MESH:D012794"},{"id":"A72","pred":"tao:has_database_id","subj":"72","obj":"MESH:D007239"},{"subj":"48","pred":"source","obj":"LitCovid-PubTator"},{"subj":"50","pred":"source","obj":"LitCovid-PubTator"},{"subj":"54","pred":"source","obj":"LitCovid-PubTator"},{"subj":"55","pred":"source","obj":"LitCovid-PubTator"},{"subj":"60","pred":"source","obj":"LitCovid-PubTator"},{"subj":"61","pred":"source","obj":"LitCovid-PubTator"},{"subj":"72","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T22","span":{"begin":0,"end":10},"obj":"SP_7"},{"id":"T23","span":{"begin":88,"end":92},"obj":"CHEBI:23888;CHEBI:23888"},{"id":"T24","span":{"begin":225,"end":230},"obj":"NCBITaxon:10239;GO:0006260"},{"id":"T25","span":{"begin":231,"end":242},"obj":"GO:0006260"},{"id":"T26","span":{"begin":273,"end":283},"obj":"GO:0009986"},{"id":"T27","span":{"begin":284,"end":295},"obj":"GO:0045333;CL:0000082"},{"id":"T28","span":{"begin":296,"end":301},"obj":"CL:0000082"},{"id":"T29","span":{"begin":329,"end":334},"obj":"NCBITaxon:10239"},{"id":"T30","span":{"begin":394,"end":403},"obj":"PG_1"},{"id":"T31","span":{"begin":447,"end":452},"obj":"G_3;PG_10;PR:000003622"},{"id":"T32","span":{"begin":483,"end":489},"obj":"CHEBI:30563;CHEBI:30563"},{"id":"T33","span":{"begin":490,"end":495},"obj":"CHEBI:41865;CHEBI:41865"}],"attributes":[{"subj":"T22","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T23","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T24","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T25","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T26","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T27","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T28","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T29","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T30","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T31","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T32","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T33","pred":"source","obj":"LitCovid-PMC-OGER-BB"}]},{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T1","span":{"begin":296,"end":301},"obj":"Body_part"},{"id":"T2","span":{"begin":335,"end":342},"obj":"Body_part"},{"id":"T3","span":{"begin":396,"end":403},"obj":"Body_part"},{"id":"T5","span":{"begin":511,"end":515},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"fma_id","subj":"T1","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A2","pred":"fma_id","subj":"T2","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A3","pred":"fma_id","subj":"T3","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A5","pred":"fma_id","subj":"T5","obj":"http://purl.org/sig/ont/fma/fma68646"},{"subj":"T1","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T2","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T3","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T5","pred":"source","obj":"LitCovid-PD-FMA-UBERON"}]},{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T7","span":{"begin":0,"end":8},"obj":"Disease"}],"attributes":[{"id":"A7","pred":"mondo_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"subj":"T7","pred":"source","obj":"LitCovid-PD-MONDO"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T3","span":{"begin":31,"end":32},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T4","span":{"begin":296,"end":301},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T5","span":{"begin":511,"end":515},"obj":"http://purl.obolibrary.org/obo/GO_0005623"}],"attributes":[{"subj":"T3","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T4","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T5","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T8","span":{"begin":88,"end":92},"obj":"Chemical"},{"id":"T9","span":{"begin":335,"end":342},"obj":"Chemical"},{"id":"T10","span":{"begin":396,"end":403},"obj":"Chemical"},{"id":"T11","span":{"begin":483,"end":495},"obj":"Chemical"},{"id":"T12","span":{"begin":490,"end":495},"obj":"Chemical"}],"attributes":[{"id":"A8","pred":"chebi_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/CHEBI_23888"},{"id":"A9","pred":"chebi_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A10","pred":"chebi_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A11","pred":"chebi_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/CHEBI_26667"},{"id":"A12","pred":"chebi_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"},{"subj":"T8","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T9","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T10","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T11","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T12","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T1","span":{"begin":225,"end":242},"obj":"http://purl.obolibrary.org/obo/GO_0019079"},{"id":"T2","span":{"begin":225,"end":242},"obj":"http://purl.obolibrary.org/obo/GO_0019058"}],"attributes":[{"subj":"T1","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T2","pred":"source","obj":"LitCovid-PD-GO-BP"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T10","span":{"begin":53,"end":202},"obj":"Sentence"},{"id":"T11","span":{"begin":203,"end":389},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T10","pred":"source","obj":"LitCovid-sentences"},{"subj":"T11","pred":"source","obj":"LitCovid-sentences"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PubTator","color":"#93ecc5","default":true},{"id":"LitCovid-PMC-OGER-BB","color":"#ecab93"},{"id":"LitCovid-PD-FMA-UBERON","color":"#9394ec"},{"id":"LitCovid-PD-MONDO","color":"#aeec93"},{"id":"LitCovid-PD-CLO","color":"#ec93c8"},{"id":"LitCovid-PD-CHEBI","color":"#93e2ec"},{"id":"LitCovid-PD-GO-BP","color":"#ecdb93"},{"id":"LitCovid-sentences","color":"#c193ec"}]}]}}