PMC:7128678 / 571-1086 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"48","span":{"begin":447,"end":452},"obj":"Gene"},{"id":"50","span":{"begin":319,"end":324},"obj":"Gene"},{"id":"54","span":{"begin":0,"end":10},"obj":"Species"},{"id":"55","span":{"begin":179,"end":187},"obj":"Species"},{"id":"60","span":{"begin":413,"end":425},"obj":"Chemical"},{"id":"61","span":{"begin":483,"end":495},"obj":"Chemical"},{"id":"72","span":{"begin":170,"end":178},"obj":"Disease"}],"attributes":[{"id":"A48","pred":"tao:has_database_id","subj":"48","obj":"Gene:59272"},{"id":"A50","pred":"tao:has_database_id","subj":"50","obj":"Gene:43740568"},{"id":"A54","pred":"tao:has_database_id","subj":"54","obj":"Tax:2697049"},{"id":"A55","pred":"tao:has_database_id","subj":"55","obj":"Tax:9606"},{"id":"A61","pred":"tao:has_database_id","subj":"61","obj":"MESH:D012794"},{"id":"A72","pred":"tao:has_database_id","subj":"72","obj":"MESH:D007239"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"SARS-CoV-2) is responsible for a worldwide pandemic. Given the global health emergency, drug repositioning is the most reliable option to design an efficient therapy for infected patients without delay. The first step of the viral replication cycle [i.e. attachment to the surface of respiratory cells, mediated by the spike (S) viral protein] offers several potential therapeutic targets. The S protein uses the angiotension-converting enzyme-2 (ACE-2) receptor for entry, but also sialic acids linked to host cell"}

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T22","span":{"begin":0,"end":10},"obj":"SP_7"},{"id":"T23","span":{"begin":88,"end":92},"obj":"CHEBI:23888;CHEBI:23888"},{"id":"T24","span":{"begin":225,"end":230},"obj":"NCBITaxon:10239;GO:0006260"},{"id":"T25","span":{"begin":231,"end":242},"obj":"GO:0006260"},{"id":"T26","span":{"begin":273,"end":283},"obj":"GO:0009986"},{"id":"T27","span":{"begin":284,"end":295},"obj":"GO:0045333;CL:0000082"},{"id":"T28","span":{"begin":296,"end":301},"obj":"CL:0000082"},{"id":"T29","span":{"begin":329,"end":334},"obj":"NCBITaxon:10239"},{"id":"T30","span":{"begin":394,"end":403},"obj":"PG_1"},{"id":"T31","span":{"begin":447,"end":452},"obj":"G_3;PG_10;PR:000003622"},{"id":"T32","span":{"begin":483,"end":489},"obj":"CHEBI:30563;CHEBI:30563"},{"id":"T33","span":{"begin":490,"end":495},"obj":"CHEBI:41865;CHEBI:41865"}],"text":"SARS-CoV-2) is responsible for a worldwide pandemic. Given the global health emergency, drug repositioning is the most reliable option to design an efficient therapy for infected patients without delay. The first step of the viral replication cycle [i.e. attachment to the surface of respiratory cells, mediated by the spike (S) viral protein] offers several potential therapeutic targets. The S protein uses the angiotension-converting enzyme-2 (ACE-2) receptor for entry, but also sialic acids linked to host cell"}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T1","span":{"begin":296,"end":301},"obj":"Body_part"},{"id":"T2","span":{"begin":335,"end":342},"obj":"Body_part"},{"id":"T3","span":{"begin":396,"end":403},"obj":"Body_part"},{"id":"T5","span":{"begin":511,"end":515},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"fma_id","subj":"T1","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A2","pred":"fma_id","subj":"T2","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A3","pred":"fma_id","subj":"T3","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A5","pred":"fma_id","subj":"T5","obj":"http://purl.org/sig/ont/fma/fma68646"}],"text":"SARS-CoV-2) is responsible for a worldwide pandemic. Given the global health emergency, drug repositioning is the most reliable option to design an efficient therapy for infected patients without delay. The first step of the viral replication cycle [i.e. attachment to the surface of respiratory cells, mediated by the spike (S) viral protein] offers several potential therapeutic targets. The S protein uses the angiotension-converting enzyme-2 (ACE-2) receptor for entry, but also sialic acids linked to host cell"}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T7","span":{"begin":0,"end":8},"obj":"Disease"}],"attributes":[{"id":"A7","pred":"mondo_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"SARS-CoV-2) is responsible for a worldwide pandemic. Given the global health emergency, drug repositioning is the most reliable option to design an efficient therapy for infected patients without delay. The first step of the viral replication cycle [i.e. attachment to the surface of respiratory cells, mediated by the spike (S) viral protein] offers several potential therapeutic targets. The S protein uses the angiotension-converting enzyme-2 (ACE-2) receptor for entry, but also sialic acids linked to host cell"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T3","span":{"begin":31,"end":32},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T4","span":{"begin":296,"end":301},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T5","span":{"begin":511,"end":515},"obj":"http://purl.obolibrary.org/obo/GO_0005623"}],"text":"SARS-CoV-2) is responsible for a worldwide pandemic. Given the global health emergency, drug repositioning is the most reliable option to design an efficient therapy for infected patients without delay. The first step of the viral replication cycle [i.e. attachment to the surface of respiratory cells, mediated by the spike (S) viral protein] offers several potential therapeutic targets. The S protein uses the angiotension-converting enzyme-2 (ACE-2) receptor for entry, but also sialic acids linked to host cell"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T8","span":{"begin":88,"end":92},"obj":"Chemical"},{"id":"T9","span":{"begin":335,"end":342},"obj":"Chemical"},{"id":"T10","span":{"begin":396,"end":403},"obj":"Chemical"},{"id":"T11","span":{"begin":483,"end":495},"obj":"Chemical"},{"id":"T12","span":{"begin":490,"end":495},"obj":"Chemical"}],"attributes":[{"id":"A8","pred":"chebi_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/CHEBI_23888"},{"id":"A9","pred":"chebi_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A10","pred":"chebi_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A11","pred":"chebi_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/CHEBI_26667"},{"id":"A12","pred":"chebi_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"}],"text":"SARS-CoV-2) is responsible for a worldwide pandemic. Given the global health emergency, drug repositioning is the most reliable option to design an efficient therapy for infected patients without delay. The first step of the viral replication cycle [i.e. attachment to the surface of respiratory cells, mediated by the spike (S) viral protein] offers several potential therapeutic targets. The S protein uses the angiotension-converting enzyme-2 (ACE-2) receptor for entry, but also sialic acids linked to host cell"}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T1","span":{"begin":225,"end":242},"obj":"http://purl.obolibrary.org/obo/GO_0019079"},{"id":"T2","span":{"begin":225,"end":242},"obj":"http://purl.obolibrary.org/obo/GO_0019058"}],"text":"SARS-CoV-2) is responsible for a worldwide pandemic. Given the global health emergency, drug repositioning is the most reliable option to design an efficient therapy for infected patients without delay. The first step of the viral replication cycle [i.e. attachment to the surface of respiratory cells, mediated by the spike (S) viral protein] offers several potential therapeutic targets. The S protein uses the angiotension-converting enzyme-2 (ACE-2) receptor for entry, but also sialic acids linked to host cell"}

{"project":"LitCovid-sentences","denotations":[{"id":"T10","span":{"begin":53,"end":202},"obj":"Sentence"},{"id":"T11","span":{"begin":203,"end":389},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"SARS-CoV-2) is responsible for a worldwide pandemic. Given the global health emergency, drug repositioning is the most reliable option to design an efficient therapy for infected patients without delay. The first step of the viral replication cycle [i.e. attachment to the surface of respiratory cells, mediated by the spike (S) viral protein] offers several potential therapeutic targets. The S protein uses the angiotension-converting enzyme-2 (ACE-2) receptor for entry, but also sialic acids linked to host cell"}