PMC:7128678 / 472-1164
Annnotations
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
21 | 11-22 | Chemical | denotes | chloroquine | MESH:D002738 |
48 | 546-551 | Gene | denotes | ACE-2 | Gene:59272 |
50 | 418-423 | Gene | denotes | spike | Gene:43740568 |
53 | 79-97 | Species | denotes | SARS-coronavirus 2 | Tax:2697049 |
54 | 99-109 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
55 | 278-286 | Species | denotes | patients | Tax:9606 |
60 | 512-524 | Chemical | denotes | angiotension | |
61 | 582-594 | Chemical | denotes | sialic acids | MESH:D012794 |
62 | 623-635 | Chemical | denotes | gangliosides | MESH:D005732 |
72 | 269-277 | Disease | denotes | infected | MESH:D007239 |
LitCovid-PMC-OGER-BB
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T11 | 11-22 | CHEBI:3638;DG_10;CHEBI:3638 | denotes | chloroquine |
T20 | 79-83 | SP_10 | denotes | SARS |
T21 | 84-95 | NCBITaxon:11118 | denotes | coronavirus |
T22 | 99-109 | SP_7 | denotes | SARS-CoV-2 |
T23 | 187-191 | CHEBI:23888;CHEBI:23888 | denotes | drug |
T24 | 324-329 | NCBITaxon:10239;GO:0006260 | denotes | viral |
T25 | 330-341 | GO:0006260 | denotes | replication |
T26 | 372-382 | GO:0009986 | denotes | surface of |
T27 | 383-394 | GO:0045333;CL:0000082 | denotes | respiratory |
T28 | 395-400 | CL:0000082 | denotes | cells |
T29 | 428-433 | NCBITaxon:10239 | denotes | viral |
T30 | 493-502 | PG_1 | denotes | S protein |
T31 | 546-551 | G_3;PG_10;PR:000003622 | denotes | ACE-2 |
T32 | 582-588 | CHEBI:30563;CHEBI:30563 | denotes | sialic |
T33 | 589-594 | CHEBI:41865;CHEBI:41865 | denotes | acids |
T34 | 605-622 | GO:0044228 | denotes | host cell surface |
T35 | 623-635 | CHEBI:28892;CHEBI:28892 | denotes | gangliosides |
T69104 | 11-22 | CHEBI:3638;DG_10;CHEBI:3638 | denotes | chloroquine |
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T1 | 395-400 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T2 | 434-441 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T3 | 495-502 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T4 | 610-622 | Body_part | denotes | cell surface | http://purl.org/sig/ont/fma/fma67653 |
T5 | 610-614 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T6 | 623-635 | Body_part | denotes | gangliosides | http://purl.org/sig/ont/fma/fma82816 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T6 | 79-95 | Disease | denotes | SARS-coronavirus | http://purl.obolibrary.org/obo/MONDO_0005091 |
T7 | 99-107 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T3 | 130-131 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T4 | 395-400 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T5 | 610-614 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
T6 | 643-644 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T7 | 11-22 | Chemical | denotes | chloroquine | http://purl.obolibrary.org/obo/CHEBI_3638 |
T8 | 187-191 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
T9 | 434-441 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T10 | 495-502 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T11 | 582-594 | Chemical | denotes | sialic acids | http://purl.obolibrary.org/obo/CHEBI_26667 |
T12 | 589-594 | Chemical | denotes | acids | http://purl.obolibrary.org/obo/CHEBI_37527 |
T13 | 623-635 | Chemical | denotes | gangliosides | http://purl.obolibrary.org/obo/CHEBI_28892 |
LitCovid-PD-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 324-341 | http://purl.obolibrary.org/obo/GO_0019079 | denotes | viral replication |
T2 | 324-341 | http://purl.obolibrary.org/obo/GO_0019058 | denotes | viral replication |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T8 | 25-33 | Sentence | denotes | Abstract |
T9 | 34-151 | Sentence | denotes | The recent emergence of the novel pathogenic SARS-coronavirus 2 (SARS-CoV-2) is responsible for a worldwide pandemic. |
T10 | 152-301 | Sentence | denotes | Given the global health emergency, drug repositioning is the most reliable option to design an efficient therapy for infected patients without delay. |
T11 | 302-488 | Sentence | denotes | The first step of the viral replication cycle [i.e. attachment to the surface of respiratory cells, mediated by the spike (S) viral protein] offers several potential therapeutic targets. |
T12 | 489-636 | Sentence | denotes | The S protein uses the angiotension-converting enzyme-2 (ACE-2) receptor for entry, but also sialic acids linked to host cell surface gangliosides. |