PMC:7128678 / 4016-4354 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"117","span":{"begin":65,"end":70},"obj":"Gene"},{"id":"118","span":{"begin":72,"end":73},"obj":"Gene"},{"id":"119","span":{"begin":169,"end":170},"obj":"Gene"},{"id":"122","span":{"begin":91,"end":101},"obj":"Species"},{"id":"130","span":{"begin":2,"end":13},"obj":"Chemical"}],"attributes":[{"id":"A117","pred":"tao:has_database_id","subj":"117","obj":"Gene:43740568"},{"id":"A118","pred":"tao:has_database_id","subj":"118","obj":"Gene:43740568"},{"id":"A119","pred":"tao:has_database_id","subj":"119","obj":"Gene:43740568"},{"id":"A122","pred":"tao:has_database_id","subj":"122","obj":"Tax:2697049"},{"id":"A130","pred":"tao:has_database_id","subj":"130","obj":"MESH:D005732"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"A ganglioside-binding site in the N-terminal domain (NTD) of the spike (S) glycoprotein of SARS-CoV-2 was identified, and CLQ was shown to be a potential blocker of the S–ganglioside interaction which occurs in the first step of the viral replication cycle (i.e. attachment to the surface of respiratory cells, mediated by the S protein)."}

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T92","span":{"begin":2,"end":13},"obj":"CHEBI:28892;CHEBI:28892"},{"id":"T93","span":{"begin":14,"end":26},"obj":"SO:0000409"},{"id":"T94","span":{"begin":45,"end":51},"obj":"SO:0000417"},{"id":"T95","span":{"begin":75,"end":87},"obj":"CHEBI:17089;CHEBI:17089;BV_11"},{"id":"T96","span":{"begin":91,"end":101},"obj":"SP_7"},{"id":"T97","span":{"begin":171,"end":182},"obj":"CHEBI:28892;CHEBI:28892"},{"id":"T98","span":{"begin":233,"end":238},"obj":"NCBITaxon:10239;GO:0006260"},{"id":"T99","span":{"begin":239,"end":250},"obj":"GO:0006260"},{"id":"T100","span":{"begin":281,"end":291},"obj":"GO:0009986"},{"id":"T101","span":{"begin":292,"end":303},"obj":"GO:0045333;CL:0000100"},{"id":"T102","span":{"begin":304,"end":309},"obj":"CL:0000100"},{"id":"T103","span":{"begin":327,"end":336},"obj":"PG_1"}],"text":"A ganglioside-binding site in the N-terminal domain (NTD) of the spike (S) glycoprotein of SARS-CoV-2 was identified, and CLQ was shown to be a potential blocker of the S–ganglioside interaction which occurs in the first step of the viral replication cycle (i.e. attachment to the surface of respiratory cells, mediated by the S protein)."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T23","span":{"begin":2,"end":13},"obj":"Body_part"},{"id":"T24","span":{"begin":75,"end":87},"obj":"Body_part"},{"id":"T25","span":{"begin":171,"end":182},"obj":"Body_part"},{"id":"T26","span":{"begin":304,"end":309},"obj":"Body_part"},{"id":"T27","span":{"begin":329,"end":336},"obj":"Body_part"}],"attributes":[{"id":"A23","pred":"fma_id","subj":"T23","obj":"http://purl.org/sig/ont/fma/fma82816"},{"id":"A24","pred":"fma_id","subj":"T24","obj":"http://purl.org/sig/ont/fma/fma62925"},{"id":"A25","pred":"fma_id","subj":"T25","obj":"http://purl.org/sig/ont/fma/fma82816"},{"id":"A26","pred":"fma_id","subj":"T26","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A27","pred":"fma_id","subj":"T27","obj":"http://purl.org/sig/ont/fma/fma67257"}],"text":"A ganglioside-binding site in the N-terminal domain (NTD) of the spike (S) glycoprotein of SARS-CoV-2 was identified, and CLQ was shown to be a potential blocker of the S–ganglioside interaction which occurs in the first step of the viral replication cycle (i.e. attachment to the surface of respiratory cells, mediated by the S protein)."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T18","span":{"begin":53,"end":56},"obj":"Disease"},{"id":"T20","span":{"begin":91,"end":99},"obj":"Disease"}],"attributes":[{"id":"A18","pred":"mondo_id","subj":"T18","obj":"http://purl.obolibrary.org/obo/MONDO_0008449"},{"id":"A19","pred":"mondo_id","subj":"T18","obj":"http://purl.obolibrary.org/obo/MONDO_0018075"},{"id":"A20","pred":"mondo_id","subj":"T20","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"A ganglioside-binding site in the N-terminal domain (NTD) of the spike (S) glycoprotein of SARS-CoV-2 was identified, and CLQ was shown to be a potential blocker of the S–ganglioside interaction which occurs in the first step of the viral replication cycle (i.e. attachment to the surface of respiratory cells, mediated by the S protein)."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T27","span":{"begin":0,"end":1},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T28","span":{"begin":142,"end":143},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T29","span":{"begin":304,"end":309},"obj":"http://purl.obolibrary.org/obo/GO_0005623"}],"text":"A ganglioside-binding site in the N-terminal domain (NTD) of the spike (S) glycoprotein of SARS-CoV-2 was identified, and CLQ was shown to be a potential blocker of the S–ganglioside interaction which occurs in the first step of the viral replication cycle (i.e. attachment to the surface of respiratory cells, mediated by the S protein)."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T45","span":{"begin":2,"end":13},"obj":"Chemical"},{"id":"T46","span":{"begin":75,"end":87},"obj":"Chemical"},{"id":"T47","span":{"begin":171,"end":182},"obj":"Chemical"},{"id":"T48","span":{"begin":329,"end":336},"obj":"Chemical"}],"attributes":[{"id":"A45","pred":"chebi_id","subj":"T45","obj":"http://purl.obolibrary.org/obo/CHEBI_28892"},{"id":"A46","pred":"chebi_id","subj":"T46","obj":"http://purl.obolibrary.org/obo/CHEBI_17089"},{"id":"A47","pred":"chebi_id","subj":"T47","obj":"http://purl.obolibrary.org/obo/CHEBI_28892"},{"id":"A48","pred":"chebi_id","subj":"T48","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"}],"text":"A ganglioside-binding site in the N-terminal domain (NTD) of the spike (S) glycoprotein of SARS-CoV-2 was identified, and CLQ was shown to be a potential blocker of the S–ganglioside interaction which occurs in the first step of the viral replication cycle (i.e. attachment to the surface of respiratory cells, mediated by the S protein)."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T5","span":{"begin":233,"end":250},"obj":"http://purl.obolibrary.org/obo/GO_0019079"},{"id":"T6","span":{"begin":233,"end":250},"obj":"http://purl.obolibrary.org/obo/GO_0019058"}],"text":"A ganglioside-binding site in the N-terminal domain (NTD) of the spike (S) glycoprotein of SARS-CoV-2 was identified, and CLQ was shown to be a potential blocker of the S–ganglioside interaction which occurs in the first step of the viral replication cycle (i.e. attachment to the surface of respiratory cells, mediated by the S protein)."}

{"project":"LitCovid-sentences","denotations":[{"id":"T30","span":{"begin":0,"end":338},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"A ganglioside-binding site in the N-terminal domain (NTD) of the spike (S) glycoprotein of SARS-CoV-2 was identified, and CLQ was shown to be a potential blocker of the S–ganglioside interaction which occurs in the first step of the viral replication cycle (i.e. attachment to the surface of respiratory cells, mediated by the S protein)."}