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PMC:7128678 / 29988-30679 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
938 116-117 Gene denotes S Gene:43740568
939 105-115 Species denotes SARS-CoV-2 Tax:2697049
940 408-418 Species denotes SARS-CoV-2 Tax:2697049
941 60-71 Chemical denotes ganglioside MESH:D005732
942 132-143 Chemical denotes ganglioside MESH:D005732
943 219-235 Chemical denotes basic amino acid MESH:D024361
944 335-346 Chemical denotes ganglioside MESH:D005732
945 626-638 Chemical denotes gangliosides MESH:D005732

LitCovid-PMC-OGER-BB

Id Subject Object Predicate Lexical cue
T670 60-71 CHEBI:5386;CHEBI:5386 denotes ganglioside
T671 80-86 SO:0000417 denotes domain
T672 105-115 SP_7 denotes SARS-CoV-2
T673 116-125 PG_1 denotes S protein
T674 132-143 CHEBI:28892;CHEBI:28892 denotes ganglioside
T675 152-158 SO:0000417 denotes domain
T676 335-346 CHEBI:28892;CHEBI:28892 denotes ganglioside
T677 355-362 SO:0000417 denotes domains
T678 408-418 SP_7 denotes SARS-CoV-2
T679 496-502 SO:0000417 denotes domain
T680 526-533 SO:0000417 denotes domains
T681 626-638 CHEBI:5386;CHEBI:5386 denotes gangliosides

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T210 60-71 Body_part denotes ganglioside http://purl.org/sig/ont/fma/fma82816
T211 118-125 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T212 132-143 Body_part denotes ganglioside http://purl.org/sig/ont/fma/fma82816
T213 225-235 Body_part denotes amino acid http://purl.org/sig/ont/fma/fma82739
T214 272-282 Body_part denotes amino acid http://purl.org/sig/ont/fma/fma82739
T215 335-346 Body_part denotes ganglioside http://purl.org/sig/ont/fma/fma82816
T216 626-638 Body_part denotes gangliosides http://purl.org/sig/ont/fma/fma82816

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T145 94-97 Disease denotes NTD http://purl.obolibrary.org/obo/MONDO_0008449|http://purl.obolibrary.org/obo/MONDO_0018075
T147 105-113 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T148 408-416 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T245 31-34 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T246 46-47 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T247 171-172 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T248 225-244 http://purl.obolibrary.org/obo/CHEBI_33708 denotes amino acid residues
T249 225-244 http://purl.obolibrary.org/obo/PR_000036907 denotes amino acid residues
T250 256-257 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T251 269-271 http://purl.obolibrary.org/obo/CLO_0001407 denotes 52
T252 272-291 http://purl.obolibrary.org/obo/CHEBI_33708 denotes amino acid residues
T253 272-291 http://purl.obolibrary.org/obo/PR_000036907 denotes amino acid residues
T254 297-300 http://purl.obolibrary.org/obo/CLO_0001002 denotes 162
T255 428-437 http://purl.obolibrary.org/obo/OBI_0000245 denotes organized
T256 477-478 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T698 60-71 Chemical denotes ganglioside http://purl.obolibrary.org/obo/CHEBI_28892
T699 118-125 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T700 132-143 Chemical denotes ganglioside http://purl.obolibrary.org/obo/CHEBI_28892
T701 225-235 Chemical denotes amino acid http://purl.obolibrary.org/obo/CHEBI_33709
T702 225-230 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T703 231-235 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T704 272-282 Chemical denotes amino acid http://purl.obolibrary.org/obo/CHEBI_33709
T705 272-277 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T706 278-282 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T707 335-346 Chemical denotes ganglioside http://purl.obolibrary.org/obo/CHEBI_28892
T708 626-638 Chemical denotes gangliosides http://purl.obolibrary.org/obo/CHEBI_28892

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T234 0-126 Sentence denotes This molecular modelling study has identified a new type of ganglioside-binding domain in the NTD of the SARS-CoV-2 S protein.
T235 127-245 Sentence denotes This ganglioside-binding domain consists of a large flat interface enriched in aromatic and basic amino acid residues.
T236 246-390 Sentence denotes It covers a stretch of 52 amino acid residues (111–162), which is longer than all linear ganglioside-binding domains characterized to date [29].
T237 391-544 Sentence denotes However, the new SARS-CoV-2 motif is organized into three distinct regions, including a central aromatic domain and two terminal basic domains (Fig. 10).
T238 545-691 Sentence denotes Thus, this motif displays the typical features that determine optimal binding to gangliosides (i.e. CH-π stacking and electrostatic interactions).