PMC:7128678 / 18051-18486 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"580","span":{"begin":75,"end":86},"obj":"Chemical"},{"id":"581","span":{"begin":231,"end":242},"obj":"Chemical"},{"id":"582","span":{"begin":279,"end":282},"obj":"Chemical"}],"attributes":[{"id":"A580","pred":"tao:has_database_id","subj":"580","obj":"MESH:D005732"},{"id":"A581","pred":"tao:has_database_id","subj":"581","obj":"MESH:D005732"},{"id":"A582","pred":"tao:has_database_id","subj":"582","obj":"MESH:D005677"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"cal chalice-like structure into which the NTD could insert its interfacial ganglioside-binding domain (Fig. 7 ). The formation of this trimolecular complex was progressive, starting with a conformational rearrangement of the first ganglioside–NTD complex triggered by the second GM1 molecule. The energy of interaction of the new complex was consistently increased by 37%, reaching an estimated value of -137 kJ.mol−1. At this stage, a"}

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T382","span":{"begin":75,"end":86},"obj":"CHEBI:5386;CHEBI:5386"},{"id":"T383","span":{"begin":95,"end":101},"obj":"SO:0000417"},{"id":"T384","span":{"begin":117,"end":129},"obj":"GO:0065003"},{"id":"T385","span":{"begin":148,"end":155},"obj":"GO:0032991"},{"id":"T386","span":{"begin":231,"end":242},"obj":"CHEBI:28892;CHEBI:28892"},{"id":"T387","span":{"begin":247,"end":254},"obj":"GO:0032991"},{"id":"T388","span":{"begin":283,"end":291},"obj":"CHEBI:36357;CHEBI:36357"},{"id":"T389","span":{"begin":330,"end":337},"obj":"GO:0032991"}],"text":"cal chalice-like structure into which the NTD could insert its interfacial ganglioside-binding domain (Fig. 7 ). The formation of this trimolecular complex was progressive, starting with a conformational rearrangement of the first ganglioside–NTD complex triggered by the second GM1 molecule. The energy of interaction of the new complex was consistently increased by 37%, reaching an estimated value of -137 kJ.mol−1. At this stage, a"}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T103","span":{"begin":75,"end":86},"obj":"Body_part"},{"id":"T104","span":{"begin":231,"end":242},"obj":"Body_part"}],"attributes":[{"id":"A103","pred":"fma_id","subj":"T103","obj":"http://purl.org/sig/ont/fma/fma82816"},{"id":"A104","pred":"fma_id","subj":"T104","obj":"http://purl.org/sig/ont/fma/fma82816"}],"text":"cal chalice-like structure into which the NTD could insert its interfacial ganglioside-binding domain (Fig. 7 ). The formation of this trimolecular complex was progressive, starting with a conformational rearrangement of the first ganglioside–NTD complex triggered by the second GM1 molecule. The energy of interaction of the new complex was consistently increased by 37%, reaching an estimated value of -137 kJ.mol−1. At this stage, a"}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T60","span":{"begin":42,"end":45},"obj":"Disease"},{"id":"T62","span":{"begin":243,"end":246},"obj":"Disease"}],"attributes":[{"id":"A60","pred":"mondo_id","subj":"T60","obj":"http://purl.obolibrary.org/obo/MONDO_0008449"},{"id":"A61","pred":"mondo_id","subj":"T60","obj":"http://purl.obolibrary.org/obo/MONDO_0018075"},{"id":"A62","pred":"mondo_id","subj":"T62","obj":"http://purl.obolibrary.org/obo/MONDO_0008449"},{"id":"A63","pred":"mondo_id","subj":"T62","obj":"http://purl.obolibrary.org/obo/MONDO_0018075"}],"text":"cal chalice-like structure into which the NTD could insert its interfacial ganglioside-binding domain (Fig. 7 ). The formation of this trimolecular complex was progressive, starting with a conformational rearrangement of the first ganglioside–NTD complex triggered by the second GM1 molecule. The energy of interaction of the new complex was consistently increased by 37%, reaching an estimated value of -137 kJ.mol−1. At this stage, a"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T131","span":{"begin":187,"end":188},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"cal chalice-like structure into which the NTD could insert its interfacial ganglioside-binding domain (Fig. 7 ). The formation of this trimolecular complex was progressive, starting with a conformational rearrangement of the first ganglioside–NTD complex triggered by the second GM1 molecule. The energy of interaction of the new complex was consistently increased by 37%, reaching an estimated value of -137 kJ.mol−1. At this stage, a"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T359","span":{"begin":75,"end":86},"obj":"Chemical"},{"id":"T360","span":{"begin":231,"end":242},"obj":"Chemical"},{"id":"T361","span":{"begin":279,"end":282},"obj":"Chemical"},{"id":"T364","span":{"begin":283,"end":291},"obj":"Chemical"}],"attributes":[{"id":"A359","pred":"chebi_id","subj":"T359","obj":"http://purl.obolibrary.org/obo/CHEBI_28892"},{"id":"A360","pred":"chebi_id","subj":"T360","obj":"http://purl.obolibrary.org/obo/CHEBI_28892"},{"id":"A361","pred":"chebi_id","subj":"T361","obj":"http://purl.obolibrary.org/obo/CHEBI_18216"},{"id":"A362","pred":"chebi_id","subj":"T361","obj":"http://purl.obolibrary.org/obo/CHEBI_61048"},{"id":"A363","pred":"chebi_id","subj":"T361","obj":"http://purl.obolibrary.org/obo/CHEBI_73110"},{"id":"A364","pred":"chebi_id","subj":"T364","obj":"http://purl.obolibrary.org/obo/CHEBI_25367"}],"text":"cal chalice-like structure into which the NTD could insert its interfacial ganglioside-binding domain (Fig. 7 ). The formation of this trimolecular complex was progressive, starting with a conformational rearrangement of the first ganglioside–NTD complex triggered by the second GM1 molecule. The energy of interaction of the new complex was consistently increased by 37%, reaching an estimated value of -137 kJ.mol−1. At this stage, a"}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T7","span":{"begin":117,"end":126},"obj":"http://purl.obolibrary.org/obo/GO_0009058"}],"text":"cal chalice-like structure into which the NTD could insert its interfacial ganglioside-binding domain (Fig. 7 ). The formation of this trimolecular complex was progressive, starting with a conformational rearrangement of the first ganglioside–NTD complex triggered by the second GM1 molecule. The energy of interaction of the new complex was consistently increased by 37%, reaching an estimated value of -137 kJ.mol−1. At this stage, a"}

{"project":"LitCovid-PD-GlycoEpitope","denotations":[{"id":"T19","span":{"begin":279,"end":282},"obj":"GlycoEpitope"}],"attributes":[{"id":"A19","pred":"glyco_epitope_db_id","subj":"T19","obj":"http://www.glycoepitope.jp/epitopes/EP0050"}],"text":"cal chalice-like structure into which the NTD could insert its interfacial ganglioside-binding domain (Fig. 7 ). The formation of this trimolecular complex was progressive, starting with a conformational rearrangement of the first ganglioside–NTD complex triggered by the second GM1 molecule. The energy of interaction of the new complex was consistently increased by 37%, reaching an estimated value of -137 kJ.mol−1. At this stage, a"}

{"project":"LitCovid-sentences","denotations":[{"id":"T128","span":{"begin":113,"end":292},"obj":"Sentence"},{"id":"T129","span":{"begin":293,"end":418},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"cal chalice-like structure into which the NTD could insert its interfacial ganglioside-binding domain (Fig. 7 ). The formation of this trimolecular complex was progressive, starting with a conformational rearrangement of the first ganglioside–NTD complex triggered by the second GM1 molecule. The energy of interaction of the new complex was consistently increased by 37%, reaching an estimated value of -137 kJ.mol−1. At this stage, a"}