PMC:7126544 / 52509-53143 JSONTXT

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    LitCovid-PD-FMA-UBERON

    {"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T176","span":{"begin":81,"end":92},"obj":"Body_part"},{"id":"T177","span":{"begin":136,"end":141},"obj":"Body_part"},{"id":"T178","span":{"begin":142,"end":149},"obj":"Body_part"},{"id":"T179","span":{"begin":156,"end":160},"obj":"Body_part"},{"id":"T180","span":{"begin":161,"end":164},"obj":"Body_part"},{"id":"T181","span":{"begin":219,"end":238},"obj":"Body_part"},{"id":"T182","span":{"begin":307,"end":311},"obj":"Body_part"},{"id":"T183","span":{"begin":339,"end":343},"obj":"Body_part"},{"id":"T184","span":{"begin":345,"end":354},"obj":"Body_part"},{"id":"T185","span":{"begin":365,"end":370},"obj":"Body_part"},{"id":"T186","span":{"begin":375,"end":380},"obj":"Body_part"},{"id":"T187","span":{"begin":397,"end":413},"obj":"Body_part"},{"id":"T188","span":{"begin":504,"end":508},"obj":"Body_part"},{"id":"T189","span":{"begin":513,"end":518},"obj":"Body_part"},{"id":"T190","span":{"begin":520,"end":529},"obj":"Body_part"},{"id":"T191","span":{"begin":551,"end":567},"obj":"Body_part"},{"id":"T192","span":{"begin":562,"end":567},"obj":"Body_part"},{"id":"T193","span":{"begin":591,"end":602},"obj":"Body_part"},{"id":"T194","span":{"begin":612,"end":617},"obj":"Body_part"},{"id":"T195","span":{"begin":622,"end":627},"obj":"Body_part"}],"attributes":[{"id":"A176","pred":"fma_id","subj":"T176","obj":"http://purl.org/sig/ont/fma/fma14515"},{"id":"A177","pred":"fma_id","subj":"T177","obj":"http://purl.org/sig/ont/fma/fma7197"},{"id":"A178","pred":"fma_id","subj":"T178","obj":"http://purl.org/sig/ont/fma/fma9637"},{"id":"A179","pred":"fma_id","subj":"T179","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A180","pred":"fma_id","subj":"T180","obj":"http://purl.org/sig/ont/fma/fma67095"},{"id":"A181","pred":"fma_id","subj":"T181","obj":"http://purl.org/sig/ont/fma/fma7158"},{"id":"A182","pred":"fma_id","subj":"T182","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A183","pred":"fma_id","subj":"T183","obj":"http://purl.org/sig/ont/fma/fma7195"},{"id":"A184","pred":"fma_id","subj":"T184","obj":"http://purl.org/sig/ont/fma/fma7131"},{"id":"A185","pred":"fma_id","subj":"T185","obj":"http://purl.org/sig/ont/fma/fma7208"},{"id":"A186","pred":"fma_id","subj":"T186","obj":"http://purl.org/sig/ont/fma/fma14543"},{"id":"A187","pred":"fma_id","subj":"T187","obj":"http://purl.org/sig/ont/fma/fma7152"},{"id":"A188","pred":"fma_id","subj":"T188","obj":"http://purl.org/sig/ont/fma/fma7195"},{"id":"A189","pred":"fma_id","subj":"T189","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A190","pred":"fma_id","subj":"T190","obj":"http://purl.org/sig/ont/fma/fma7131"},{"id":"A191","pred":"fma_id","subj":"T191","obj":"http://purl.org/sig/ont/fma/fma66768"},{"id":"A192","pred":"fma_id","subj":"T192","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A193","pred":"fma_id","subj":"T193","obj":"http://purl.org/sig/ont/fma/fma62122"},{"id":"A194","pred":"fma_id","subj":"T194","obj":"http://purl.org/sig/ont/fma/fma7208"},{"id":"A195","pred":"fma_id","subj":"T195","obj":"http://purl.org/sig/ont/fma/fma14543"}],"text":"SARS-CoV-2 may directly bind to ACE2 positive cholangiocytes but not necessarily hepatocytes via specific expression of ACE2 in healthy liver tissues using cell RNA-seq data of two independent cohorts [126]. Though the respiratory systems is a primary target of SARS-CoV-2, bioinformatic analysis of single-cell transcriptomes datasets of lung, esophagus, gastric, ileum and colon reveal that the digestive system is also a potential route of entry for COVID-19, as ACE2 was not only highly expressed in lung AT2 cells, esophagus upper and stratified epithelial cells but also in absorptive enterocytes from the ileum and colon [127]."}

    LitCovid-PD-UBERON

    {"project":"LitCovid-PD-UBERON","denotations":[{"id":"T57","span":{"begin":136,"end":141},"obj":"Body_part"},{"id":"T58","span":{"begin":219,"end":238},"obj":"Body_part"},{"id":"T59","span":{"begin":339,"end":343},"obj":"Body_part"},{"id":"T60","span":{"begin":345,"end":354},"obj":"Body_part"},{"id":"T61","span":{"begin":365,"end":370},"obj":"Body_part"},{"id":"T62","span":{"begin":375,"end":380},"obj":"Body_part"},{"id":"T63","span":{"begin":397,"end":413},"obj":"Body_part"},{"id":"T64","span":{"begin":504,"end":508},"obj":"Body_part"},{"id":"T65","span":{"begin":520,"end":529},"obj":"Body_part"},{"id":"T66","span":{"begin":612,"end":617},"obj":"Body_part"},{"id":"T67","span":{"begin":622,"end":627},"obj":"Body_part"}],"attributes":[{"id":"A57","pred":"uberon_id","subj":"T57","obj":"http://purl.obolibrary.org/obo/UBERON_0002107"},{"id":"A58","pred":"uberon_id","subj":"T58","obj":"http://purl.obolibrary.org/obo/UBERON_0001004"},{"id":"A59","pred":"uberon_id","subj":"T59","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"A60","pred":"uberon_id","subj":"T60","obj":"http://purl.obolibrary.org/obo/UBERON_0001043"},{"id":"A61","pred":"uberon_id","subj":"T61","obj":"http://purl.obolibrary.org/obo/UBERON_0002116"},{"id":"A62","pred":"uberon_id","subj":"T62","obj":"http://purl.obolibrary.org/obo/UBERON_0001155"},{"id":"A63","pred":"uberon_id","subj":"T63","obj":"http://purl.obolibrary.org/obo/UBERON_0001007"},{"id":"A64","pred":"uberon_id","subj":"T64","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"A65","pred":"uberon_id","subj":"T65","obj":"http://purl.obolibrary.org/obo/UBERON_0001043"},{"id":"A66","pred":"uberon_id","subj":"T66","obj":"http://purl.obolibrary.org/obo/UBERON_0002116"},{"id":"A67","pred":"uberon_id","subj":"T67","obj":"http://purl.obolibrary.org/obo/UBERON_0001155"}],"text":"SARS-CoV-2 may directly bind to ACE2 positive cholangiocytes but not necessarily hepatocytes via specific expression of ACE2 in healthy liver tissues using cell RNA-seq data of two independent cohorts [126]. Though the respiratory systems is a primary target of SARS-CoV-2, bioinformatic analysis of single-cell transcriptomes datasets of lung, esophagus, gastric, ileum and colon reveal that the digestive system is also a potential route of entry for COVID-19, as ACE2 was not only highly expressed in lung AT2 cells, esophagus upper and stratified epithelial cells but also in absorptive enterocytes from the ileum and colon [127]."}

    LitCovid-PD-MONDO

    {"project":"LitCovid-PD-MONDO","denotations":[{"id":"T466","span":{"begin":0,"end":8},"obj":"Disease"},{"id":"T467","span":{"begin":0,"end":4},"obj":"Disease"},{"id":"T468","span":{"begin":262,"end":270},"obj":"Disease"},{"id":"T469","span":{"begin":262,"end":266},"obj":"Disease"},{"id":"T470","span":{"begin":453,"end":461},"obj":"Disease"}],"attributes":[{"id":"A466","pred":"mondo_id","subj":"T466","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A467","pred":"mondo_id","subj":"T467","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A468","pred":"mondo_id","subj":"T468","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A469","pred":"mondo_id","subj":"T469","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A470","pred":"mondo_id","subj":"T470","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"}],"text":"SARS-CoV-2 may directly bind to ACE2 positive cholangiocytes but not necessarily hepatocytes via specific expression of ACE2 in healthy liver tissues using cell RNA-seq data of two independent cohorts [126]. Though the respiratory systems is a primary target of SARS-CoV-2, bioinformatic analysis of single-cell transcriptomes datasets of lung, esophagus, gastric, ileum and colon reveal that the digestive system is also a potential route of entry for COVID-19, as ACE2 was not only highly expressed in lung AT2 cells, esophagus upper and stratified epithelial cells but also in absorptive enterocytes from the ileum and colon [127]."}

    LitCovid-PD-CLO

    {"project":"LitCovid-PD-CLO","denotations":[{"id":"T464","span":{"begin":136,"end":141},"obj":"http://purl.obolibrary.org/obo/UBERON_0002107"},{"id":"T465","span":{"begin":136,"end":141},"obj":"http://www.ebi.ac.uk/efo/EFO_0000887"},{"id":"T466","span":{"begin":156,"end":160},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T467","span":{"begin":219,"end":238},"obj":"http://purl.obolibrary.org/obo/UBERON_0001004"},{"id":"T468","span":{"begin":242,"end":243},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T469","span":{"begin":307,"end":311},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T470","span":{"begin":339,"end":343},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T471","span":{"begin":339,"end":343},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T472","span":{"begin":345,"end":354},"obj":"http://purl.obolibrary.org/obo/UBERON_0001043"},{"id":"T473","span":{"begin":365,"end":370},"obj":"http://purl.obolibrary.org/obo/UBERON_0002116"},{"id":"T474","span":{"begin":375,"end":380},"obj":"http://purl.obolibrary.org/obo/UBERON_0001155"},{"id":"T475","span":{"begin":397,"end":413},"obj":"http://purl.obolibrary.org/obo/UBERON_0001007"},{"id":"T476","span":{"begin":397,"end":413},"obj":"http://www.ebi.ac.uk/efo/EFO_0000793"},{"id":"T477","span":{"begin":422,"end":423},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T478","span":{"begin":504,"end":508},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T479","span":{"begin":504,"end":508},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T480","span":{"begin":513,"end":518},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T481","span":{"begin":520,"end":529},"obj":"http://purl.obolibrary.org/obo/UBERON_0001043"},{"id":"T482","span":{"begin":540,"end":567},"obj":"http://purl.obolibrary.org/obo/CL_0000079"},{"id":"T483","span":{"begin":612,"end":617},"obj":"http://purl.obolibrary.org/obo/UBERON_0002116"},{"id":"T484","span":{"begin":622,"end":627},"obj":"http://purl.obolibrary.org/obo/UBERON_0001155"}],"text":"SARS-CoV-2 may directly bind to ACE2 positive cholangiocytes but not necessarily hepatocytes via specific expression of ACE2 in healthy liver tissues using cell RNA-seq data of two independent cohorts [126]. Though the respiratory systems is a primary target of SARS-CoV-2, bioinformatic analysis of single-cell transcriptomes datasets of lung, esophagus, gastric, ileum and colon reveal that the digestive system is also a potential route of entry for COVID-19, as ACE2 was not only highly expressed in lung AT2 cells, esophagus upper and stratified epithelial cells but also in absorptive enterocytes from the ileum and colon [127]."}

    LitCovid-sentences

    {"project":"LitCovid-sentences","denotations":[{"id":"T424","span":{"begin":0,"end":207},"obj":"Sentence"},{"id":"T425","span":{"begin":208,"end":634},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"SARS-CoV-2 may directly bind to ACE2 positive cholangiocytes but not necessarily hepatocytes via specific expression of ACE2 in healthy liver tissues using cell RNA-seq data of two independent cohorts [126]. Though the respiratory systems is a primary target of SARS-CoV-2, bioinformatic analysis of single-cell transcriptomes datasets of lung, esophagus, gastric, ileum and colon reveal that the digestive system is also a potential route of entry for COVID-19, as ACE2 was not only highly expressed in lung AT2 cells, esophagus upper and stratified epithelial cells but also in absorptive enterocytes from the ileum and colon [127]."}

    LitCovid-PubTator

    {"project":"LitCovid-PubTator","denotations":[{"id":"1401","span":{"begin":32,"end":36},"obj":"Gene"},{"id":"1402","span":{"begin":120,"end":124},"obj":"Gene"},{"id":"1403","span":{"begin":466,"end":470},"obj":"Gene"},{"id":"1404","span":{"begin":0,"end":10},"obj":"Species"},{"id":"1405","span":{"begin":262,"end":272},"obj":"Species"},{"id":"1406","span":{"begin":219,"end":230},"obj":"Species"},{"id":"1407","span":{"begin":453,"end":461},"obj":"Disease"}],"attributes":[{"id":"A1401","pred":"tao:has_database_id","subj":"1401","obj":"Gene:59272"},{"id":"A1402","pred":"tao:has_database_id","subj":"1402","obj":"Gene:59272"},{"id":"A1403","pred":"tao:has_database_id","subj":"1403","obj":"Gene:59272"},{"id":"A1404","pred":"tao:has_database_id","subj":"1404","obj":"Tax:2697049"},{"id":"A1405","pred":"tao:has_database_id","subj":"1405","obj":"Tax:2697049"},{"id":"A1406","pred":"tao:has_database_id","subj":"1406","obj":"Tax:12814"},{"id":"A1407","pred":"tao:has_database_id","subj":"1407","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"SARS-CoV-2 may directly bind to ACE2 positive cholangiocytes but not necessarily hepatocytes via specific expression of ACE2 in healthy liver tissues using cell RNA-seq data of two independent cohorts [126]. Though the respiratory systems is a primary target of SARS-CoV-2, bioinformatic analysis of single-cell transcriptomes datasets of lung, esophagus, gastric, ileum and colon reveal that the digestive system is also a potential route of entry for COVID-19, as ACE2 was not only highly expressed in lung AT2 cells, esophagus upper and stratified epithelial cells but also in absorptive enterocytes from the ileum and colon [127]."}