PMC:7126544 / 36498-39707 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7126544","sourcedb":"PMC","sourceid":"7126544","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7126544","text":"7 Diagnosis\nThe earliest cases of SARS-CoV-2 were identified as “pneumonia of unknown etiology”, which was defined as an illness of unknown etiology with 1. Fever with or without a recorded temperature 2. Radiographic evidence of pneumonia 3. Low or normal leukocyte count or low lymphocyte count during the early stage of disease and 4. No improvement or worsening symptoms after 3–5 days of antimicrobial treatment per standard clinical guidelines [61]. With increasing research and knowledge of the disease, diagnosis and treatment guidelines have been continuously updated. At present, the NHC has issued the fifth edition of the guidelines. However, because of a shortage of diagnostic reagents for SARS-CoV-2 detection, different guidelines or programs emphasized comprehensive analysis based on epidemiological history, clinical manifestations and imaging examinations in diagnosis.\n\n7.1 Diagnostic criteria [37,[78], [79], [80], [81], [82]]\nThe diagnostic criteria of suspected and confirmed cases were summarized in Table 1 .\nTable 1 The diagnostic criteria for suspected and confirmed cases [37,[77], [78], [79], [80], [81]].\nCase Diagnostic criteria\nSuspected case Anyone with a history of epidemiology and any two of the clinical manifestations or anyone without epidemiological history and three of the clinical manifestations is considered to be a suspected case:\n(1) Epidemiological history:1) within 14 days before the disease onset, there is a travel history or living history in Wuhan or other areas with local cases\n2) within 14 days before the disease onset, there is contact with patients who had fever or respiratory symptoms from Wuhan or other areas with local cases\n3) a clustering of patients or a contact with patients infected with the SARS-CoV-2\n(2) Clinical manifestations:1) fever and/or respiratory symptoms\n2) with the above-mentioned imaging characteristics of pneumonia\n3) the total number of leukocytes in the early stage of the disease is normal or decreased, or the lymphocyte count is decreased\nConfirmed case Any suspected case with one of the following pathogenic features is reclassified as a confirmed case:\n(1) Positive results of SARS-CoV-2 nucleic acids by RT-PCR of respiratory or blood specimens\n(2) DNA highly homologous to SARS-CoV-2 by genetic sequencing of viral genes in respiratory or blood specimens\nRT-PCR: real-time reverse-transcriptase polymerase-chain-reaction.\n\n7.2 Differential diagnosis\nThe SARS-CoV-2 needs to be distinguished from other known viral pneumonias including influenza virus, parainfluenza virus, adenovirus, respiratory syncytial virus, rhinovirus, human metapneumovirus, SARS coronavirus, MERS coronavirus, as well as Mycoplasma pneumoniae, chlamydia pneumonia, and bacterial pneumonias. For patients with underlying diseases, attention should be paid to the detection of invasive fungal infections. The differential diagnosis also includes non-infectious diseases such as vasculitis, dermatomyositis, and organizing pneumonia. It should be noted that often patients with viral pneumonia may test positive to multiple viruses, and the potential lethality of a combined SARS-CoV-2/influenza virus infection should not be ignored.","divisions":[{"label":"label","span":{"begin":0,"end":1}},{"label":"title","span":{"begin":3,"end":12}},{"label":"p","span":{"begin":13,"end":890}},{"label":"sec","span":{"begin":892,"end":2423}},{"label":"label","span":{"begin":892,"end":895}},{"label":"title","span":{"begin":897,"end":950}},{"label":"p","span":{"begin":951,"end":2423}},{"label":"table-wrap","span":{"begin":1037,"end":2423}},{"label":"label","span":{"begin":1037,"end":1044}},{"label":"caption","span":{"begin":1045,"end":1137}},{"label":"p","span":{"begin":1045,"end":1137}},{"label":"table","span":{"begin":1138,"end":2356}},{"label":"tr","span":{"begin":1138,"end":1162}},{"label":"td","span":{"begin":1138,"end":1142}},{"label":"td","span":{"begin":1143,"end":1162}},{"label":"tr","span":{"begin":1163,"end":1379}},{"label":"td","span":{"begin":1163,"end":1177}},{"label":"td","span":{"begin":1178,"end":1379}},{"label":"tr","span":{"begin":1380,"end":1776}},{"label":"td","span":{"begin":1380,"end":1776}},{"label":"label","span":{"begin":1380,"end":1383}},{"label":"p","span":{"begin":1384,"end":1776}},{"label":"label","span":{"begin":1408,"end":1410}},{"label":"p","span":{"begin":1411,"end":1536}},{"label":"label","span":{"begin":1537,"end":1539}},{"label":"p","span":{"begin":1540,"end":1692}},{"label":"label","span":{"begin":1693,"end":1695}},{"label":"p","span":{"begin":1696,"end":1776}},{"label":"tr","span":{"begin":1777,"end":2035}},{"label":"td","span":{"begin":1777,"end":2035}},{"label":"label","span":{"begin":1777,"end":1780}},{"label":"p","span":{"begin":1781,"end":2035}},{"label":"label","span":{"begin":1805,"end":1807}},{"label":"p","span":{"begin":1808,"end":1841}},{"label":"label","span":{"begin":1842,"end":1844}},{"label":"p","span":{"begin":1845,"end":1906}},{"label":"label","span":{"begin":1907,"end":1909}},{"label":"p","span":{"begin":1910,"end":2035}},{"label":"tr","span":{"begin":2036,"end":2152}},{"label":"td","span":{"begin":2036,"end":2050}},{"label":"td","span":{"begin":2051,"end":2152}},{"label":"tr","span":{"begin":2153,"end":2356}},{"label":"td","span":{"begin":2153,"end":2356}},{"label":"label","span":{"begin":2153,"end":2156}},{"label":"p","span":{"begin":2157,"end":2245}},{"label":"label","span":{"begin":2246,"end":2249}},{"label":"p","span":{"begin":2250,"end":2356}},{"label":"table-wrap-foot","span":{"begin":2357,"end":2423}},{"label":"footnote","span":{"begin":2357,"end":2423}},{"label":"p","span":{"begin":2357,"end":2423}},{"label":"label","span":{"begin":2425,"end":2428}},{"label":"title","span":{"begin":2430,"end":2452}}],"tracks":[{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T78","span":{"begin":258,"end":267},"obj":"Body_part"},{"id":"T79","span":{"begin":281,"end":291},"obj":"Body_part"},{"id":"T80","span":{"begin":1930,"end":1940},"obj":"Body_part"},{"id":"T81","span":{"begin":2006,"end":2016},"obj":"Body_part"},{"id":"T82","span":{"begin":2230,"end":2235},"obj":"Body_part"},{"id":"T83","span":{"begin":2250,"end":2253},"obj":"Body_part"},{"id":"T84","span":{"begin":2341,"end":2346},"obj":"Body_part"}],"attributes":[{"id":"A78","pred":"fma_id","subj":"T78","obj":"http://purl.org/sig/ont/fma/fma62852"},{"id":"A79","pred":"fma_id","subj":"T79","obj":"http://purl.org/sig/ont/fma/fma62863"},{"id":"A80","pred":"fma_id","subj":"T80","obj":"http://purl.org/sig/ont/fma/fma62852"},{"id":"A81","pred":"fma_id","subj":"T81","obj":"http://purl.org/sig/ont/fma/fma62863"},{"id":"A82","pred":"fma_id","subj":"T82","obj":"http://purl.org/sig/ont/fma/fma9670"},{"id":"A83","pred":"fma_id","subj":"T83","obj":"http://purl.org/sig/ont/fma/fma74412"},{"id":"A84","pred":"fma_id","subj":"T84","obj":"http://purl.org/sig/ont/fma/fma9670"},{"subj":"T78","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T79","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T80","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T81","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T82","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T83","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T84","pred":"source","obj":"LitCovid-PD-FMA-UBERON"}]},{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T42","span":{"begin":2230,"end":2235},"obj":"Body_part"},{"id":"T43","span":{"begin":2341,"end":2346},"obj":"Body_part"}],"attributes":[{"id":"A42","pred":"uberon_id","subj":"T42","obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"A43","pred":"uberon_id","subj":"T43","obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"subj":"T42","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T43","pred":"source","obj":"LitCovid-PD-UBERON"}]},{"project":"LitCovid-PD-HP","denotations":[{"id":"T102","span":{"begin":66,"end":75},"obj":"Phenotype"},{"id":"T103","span":{"begin":158,"end":163},"obj":"Phenotype"},{"id":"T104","span":{"begin":231,"end":240},"obj":"Phenotype"},{"id":"T105","span":{"begin":1620,"end":1625},"obj":"Phenotype"},{"id":"T106","span":{"begin":1808,"end":1813},"obj":"Phenotype"},{"id":"T107","span":{"begin":1897,"end":1906},"obj":"Phenotype"},{"id":"T108","span":{"begin":2517,"end":2527},"obj":"Phenotype"},{"id":"T109","span":{"begin":2710,"end":2720},"obj":"Phenotype"},{"id":"T110","span":{"begin":2732,"end":2741},"obj":"Phenotype"},{"id":"T111","span":{"begin":2757,"end":2767},"obj":"Phenotype"},{"id":"T112","span":{"begin":2853,"end":2879},"obj":"Phenotype"},{"id":"T113","span":{"begin":2954,"end":2964},"obj":"Phenotype"},{"id":"T114","span":{"begin":2998,"end":3007},"obj":"Phenotype"},{"id":"T115","span":{"begin":3059,"end":3068},"obj":"Phenotype"}],"attributes":[{"id":"A102","pred":"hp_id","subj":"T102","obj":"http://purl.obolibrary.org/obo/HP_0002090"},{"id":"A103","pred":"hp_id","subj":"T103","obj":"http://purl.obolibrary.org/obo/HP_0001945"},{"id":"A104","pred":"hp_id","subj":"T104","obj":"http://purl.obolibrary.org/obo/HP_0002090"},{"id":"A105","pred":"hp_id","subj":"T105","obj":"http://purl.obolibrary.org/obo/HP_0001945"},{"id":"A106","pred":"hp_id","subj":"T106","obj":"http://purl.obolibrary.org/obo/HP_0001945"},{"id":"A107","pred":"hp_id","subj":"T107","obj":"http://purl.obolibrary.org/obo/HP_0002090"},{"id":"A108","pred":"hp_id","subj":"T108","obj":"http://purl.obolibrary.org/obo/HP_0002090"},{"id":"A109","pred":"hp_id","subj":"T109","obj":"http://purl.obolibrary.org/obo/HP_0002090"},{"id":"A110","pred":"hp_id","subj":"T110","obj":"http://purl.obolibrary.org/obo/HP_0002090"},{"id":"A111","pred":"hp_id","subj":"T111","obj":"http://purl.obolibrary.org/obo/HP_0002090"},{"id":"A112","pred":"hp_id","subj":"T112","obj":"http://purl.obolibrary.org/obo/HP_0020101"},{"id":"A113","pred":"hp_id","subj":"T113","obj":"http://purl.obolibrary.org/obo/HP_0002633"},{"id":"A114","pred":"hp_id","subj":"T114","obj":"http://purl.obolibrary.org/obo/HP_0002090"},{"id":"A115","pred":"hp_id","subj":"T115","obj":"http://purl.obolibrary.org/obo/HP_0002090"},{"subj":"T102","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T103","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T104","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T105","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T106","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T107","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T108","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T109","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T110","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T111","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T112","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T113","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T114","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T115","pred":"source","obj":"LitCovid-PD-HP"}]},{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T287","span":{"begin":35,"end":43},"obj":"Disease"},{"id":"T288","span":{"begin":35,"end":39},"obj":"Disease"},{"id":"T289","span":{"begin":66,"end":75},"obj":"Disease"},{"id":"T290","span":{"begin":231,"end":240},"obj":"Disease"},{"id":"T291","span":{"begin":705,"end":713},"obj":"Disease"},{"id":"T292","span":{"begin":705,"end":709},"obj":"Disease"},{"id":"T293","span":{"begin":1766,"end":1774},"obj":"Disease"},{"id":"T294","span":{"begin":1766,"end":1770},"obj":"Disease"},{"id":"T295","span":{"begin":1897,"end":1906},"obj":"Disease"},{"id":"T296","span":{"begin":2177,"end":2185},"obj":"Disease"},{"id":"T297","span":{"begin":2177,"end":2181},"obj":"Disease"},{"id":"T298","span":{"begin":2275,"end":2283},"obj":"Disease"},{"id":"T299","span":{"begin":2275,"end":2279},"obj":"Disease"},{"id":"T300","span":{"begin":2457,"end":2465},"obj":"Disease"},{"id":"T301","span":{"begin":2457,"end":2461},"obj":"Disease"},{"id":"T302","span":{"begin":2511,"end":2527},"obj":"Disease"},{"id":"T303","span":{"begin":2538,"end":2547},"obj":"Disease"},{"id":"T304","span":{"begin":2652,"end":2656},"obj":"Disease"},{"id":"T305","span":{"begin":2699,"end":2720},"obj":"Disease"},{"id":"T306","span":{"begin":2722,"end":2741},"obj":"Disease"},{"id":"T307","span":{"begin":2722,"end":2731},"obj":"Disease"},{"id":"T308","span":{"begin":2732,"end":2741},"obj":"Disease"},{"id":"T309","span":{"begin":2747,"end":2767},"obj":"Disease"},{"id":"T310","span":{"begin":2862,"end":2879},"obj":"Disease"},{"id":"T311","span":{"begin":2926,"end":2936},"obj":"Disease"},{"id":"T312","span":{"begin":2954,"end":2964},"obj":"Disease"},{"id":"T313","span":{"begin":2966,"end":2981},"obj":"Disease"},{"id":"T314","span":{"begin":2987,"end":3007},"obj":"Disease"},{"id":"T316","span":{"begin":2998,"end":3007},"obj":"Disease"},{"id":"T317","span":{"begin":3053,"end":3068},"obj":"Disease"},{"id":"T318","span":{"begin":3059,"end":3068},"obj":"Disease"},{"id":"T319","span":{"begin":3150,"end":3158},"obj":"Disease"},{"id":"T320","span":{"begin":3150,"end":3154},"obj":"Disease"},{"id":"T321","span":{"begin":3161,"end":3170},"obj":"Disease"},{"id":"T322","span":{"begin":3171,"end":3186},"obj":"Disease"},{"id":"T323","span":{"begin":3177,"end":3186},"obj":"Disease"}],"attributes":[{"id":"A287","pred":"mondo_id","subj":"T287","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A288","pred":"mondo_id","subj":"T288","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A289","pred":"mondo_id","subj":"T289","obj":"http://purl.obolibrary.org/obo/MONDO_0005249"},{"id":"A290","pred":"mondo_id","subj":"T290","obj":"http://purl.obolibrary.org/obo/MONDO_0005249"},{"id":"A291","pred":"mondo_id","subj":"T291","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A292","pred":"mondo_id","subj":"T292","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A293","pred":"mondo_id","subj":"T293","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A294","pred":"mondo_id","subj":"T294","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A295","pred":"mondo_id","subj":"T295","obj":"http://purl.obolibrary.org/obo/MONDO_0005249"},{"id":"A296","pred":"mondo_id","subj":"T296","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A297","pred":"mondo_id","subj":"T297","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A298","pred":"mondo_id","subj":"T298","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A299","pred":"mondo_id","subj":"T299","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A300","pred":"mondo_id","subj":"T300","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A301","pred":"mondo_id","subj":"T301","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A302","pred":"mondo_id","subj":"T302","obj":"http://purl.obolibrary.org/obo/MONDO_0006012"},{"id":"A303","pred":"mondo_id","subj":"T303","obj":"http://purl.obolibrary.org/obo/MONDO_0005812"},{"id":"A304","pred":"mondo_id","subj":"T304","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A305","pred":"mondo_id","subj":"T305","obj":"http://purl.obolibrary.org/obo/MONDO_0005867"},{"id":"A306","pred":"mondo_id","subj":"T306","obj":"http://purl.obolibrary.org/obo/MONDO_0025598"},{"id":"A307","pred":"mondo_id","subj":"T307","obj":"http://purl.obolibrary.org/obo/MONDO_0005701"},{"id":"A308","pred":"mondo_id","subj":"T308","obj":"http://purl.obolibrary.org/obo/MONDO_0005249"},{"id":"A309","pred":"mondo_id","subj":"T309","obj":"http://purl.obolibrary.org/obo/MONDO_0004652"},{"id":"A310","pred":"mondo_id","subj":"T310","obj":"http://purl.obolibrary.org/obo/MONDO_0002041"},{"id":"A311","pred":"mondo_id","subj":"T311","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A312","pred":"mondo_id","subj":"T312","obj":"http://purl.obolibrary.org/obo/MONDO_0018882"},{"id":"A313","pred":"mondo_id","subj":"T313","obj":"http://purl.obolibrary.org/obo/MONDO_0016367"},{"id":"A314","pred":"mondo_id","subj":"T314","obj":"http://purl.obolibrary.org/obo/MONDO_0015265"},{"id":"A315","pred":"mondo_id","subj":"T314","obj":"http://purl.obolibrary.org/obo/MONDO_0056821"},{"id":"A316","pred":"mondo_id","subj":"T316","obj":"http://purl.obolibrary.org/obo/MONDO_0005249"},{"id":"A317","pred":"mondo_id","subj":"T317","obj":"http://purl.obolibrary.org/obo/MONDO_0006012"},{"id":"A318","pred":"mondo_id","subj":"T318","obj":"http://purl.obolibrary.org/obo/MONDO_0005249"},{"id":"A319","pred":"mondo_id","subj":"T319","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A320","pred":"mondo_id","subj":"T320","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A321","pred":"mondo_id","subj":"T321","obj":"http://purl.obolibrary.org/obo/MONDO_0005812"},{"id":"A322","pred":"mondo_id","subj":"T322","obj":"http://purl.obolibrary.org/obo/MONDO_0005108"},{"id":"A323","pred":"mondo_id","subj":"T323","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"subj":"T287","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T288","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T289","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T290","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T291","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T292","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T293","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T294","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T295","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T296","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T297","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T298","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T299","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T300","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T301","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T302","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T303","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T304","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T305","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T306","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T307","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T308","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T309","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T310","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T311","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T312","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T313","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T314","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T316","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T317","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T318","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T319","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T320","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T321","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T322","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T323","pred":"source","obj":"LitCovid-PD-MONDO"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T302","span":{"begin":180,"end":181},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T303","span":{"begin":382,"end":385},"obj":"http://purl.obolibrary.org/obo/CLO_0001000"},{"id":"T304","span":{"begin":599,"end":602},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T305","span":{"begin":667,"end":668},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T306","span":{"begin":1190,"end":1191},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T307","span":{"begin":1362,"end":1363},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T308","span":{"begin":1461,"end":1462},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T309","span":{"begin":1696,"end":1697},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T310","span":{"begin":1724,"end":1725},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T311","span":{"begin":2135,"end":2136},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T312","span":{"begin":2230,"end":2235},"obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"T313","span":{"begin":2230,"end":2235},"obj":"http://www.ebi.ac.uk/efo/EFO_0000296"},{"id":"T314","span":{"begin":2317,"end":2322},"obj":"http://purl.obolibrary.org/obo/OGG_0000000002"},{"id":"T315","span":{"begin":2341,"end":2346},"obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"T316","span":{"begin":2341,"end":2346},"obj":"http://www.ebi.ac.uk/efo/EFO_0000296"},{"id":"T317","span":{"begin":2548,"end":2553},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T318","span":{"begin":2569,"end":2574},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T319","span":{"begin":2610,"end":2615},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T320","span":{"begin":2629,"end":2634},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T321","span":{"begin":2987,"end":2997},"obj":"http://purl.obolibrary.org/obo/OBI_0000245"},{"id":"T322","span":{"begin":3073,"end":3077},"obj":"http://purl.obolibrary.org/obo/UBERON_0000473"},{"id":"T323","span":{"begin":3099,"end":3106},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T324","span":{"begin":3139,"end":3140},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T325","span":{"begin":3171,"end":3176},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"}],"attributes":[{"subj":"T302","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T303","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T304","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T305","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T306","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T307","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T308","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T309","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T310","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T311","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T312","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T313","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T314","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T315","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T316","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T317","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T318","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T319","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T320","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T321","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T322","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T323","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T324","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T325","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T62","span":{"begin":394,"end":407},"obj":"Chemical"},{"id":"T63","span":{"begin":595,"end":598},"obj":"Chemical"},{"id":"T64","span":{"begin":692,"end":700},"obj":"Chemical"},{"id":"T65","span":{"begin":2188,"end":2201},"obj":"Chemical"},{"id":"T66","span":{"begin":2196,"end":2201},"obj":"Chemical"},{"id":"T67","span":{"begin":2250,"end":2253},"obj":"Chemical"}],"attributes":[{"id":"A62","pred":"chebi_id","subj":"T62","obj":"http://purl.obolibrary.org/obo/CHEBI_33281"},{"id":"A63","pred":"chebi_id","subj":"T63","obj":"http://purl.obolibrary.org/obo/CHEBI_51369"},{"id":"A64","pred":"chebi_id","subj":"T64","obj":"http://purl.obolibrary.org/obo/CHEBI_33893"},{"id":"A65","pred":"chebi_id","subj":"T65","obj":"http://purl.obolibrary.org/obo/CHEBI_33696"},{"id":"A66","pred":"chebi_id","subj":"T66","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"},{"id":"A67","pred":"chebi_id","subj":"T67","obj":"http://purl.obolibrary.org/obo/CHEBI_16991"},{"subj":"T62","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T63","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T64","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T65","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T66","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T67","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T23","span":{"begin":2383,"end":2396},"obj":"http://purl.obolibrary.org/obo/GO_0003968"},{"id":"T24","span":{"begin":2383,"end":2396},"obj":"http://purl.obolibrary.org/obo/GO_0003899"}],"attributes":[{"subj":"T23","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T24","pred":"source","obj":"LitCovid-PD-GO-BP"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T305","span":{"begin":0,"end":12},"obj":"Sentence"},{"id":"T306","span":{"begin":13,"end":157},"obj":"Sentence"},{"id":"T307","span":{"begin":158,"end":205},"obj":"Sentence"},{"id":"T308","span":{"begin":206,"end":243},"obj":"Sentence"},{"id":"T309","span":{"begin":244,"end":338},"obj":"Sentence"},{"id":"T310","span":{"begin":339,"end":456},"obj":"Sentence"},{"id":"T311","span":{"begin":457,"end":578},"obj":"Sentence"},{"id":"T312","span":{"begin":579,"end":646},"obj":"Sentence"},{"id":"T313","span":{"begin":647,"end":890},"obj":"Sentence"},{"id":"T314","span":{"begin":892,"end":950},"obj":"Sentence"},{"id":"T315","span":{"begin":951,"end":1036},"obj":"Sentence"},{"id":"T316","span":{"begin":1037,"end":1137},"obj":"Sentence"},{"id":"T317","span":{"begin":1138,"end":1162},"obj":"Sentence"},{"id":"T318","span":{"begin":1163,"end":1379},"obj":"Sentence"},{"id":"T319","span":{"begin":1380,"end":1536},"obj":"Sentence"},{"id":"T320","span":{"begin":1537,"end":1692},"obj":"Sentence"},{"id":"T321","span":{"begin":1693,"end":1776},"obj":"Sentence"},{"id":"T322","span":{"begin":1777,"end":1841},"obj":"Sentence"},{"id":"T323","span":{"begin":1842,"end":1906},"obj":"Sentence"},{"id":"T324","span":{"begin":1907,"end":2035},"obj":"Sentence"},{"id":"T325","span":{"begin":2036,"end":2152},"obj":"Sentence"},{"id":"T326","span":{"begin":2153,"end":2245},"obj":"Sentence"},{"id":"T327","span":{"begin":2246,"end":2356},"obj":"Sentence"},{"id":"T328","span":{"begin":2357,"end":2423},"obj":"Sentence"},{"id":"T329","span":{"begin":2425,"end":2452},"obj":"Sentence"},{"id":"T330","span":{"begin":2453,"end":2768},"obj":"Sentence"},{"id":"T331","span":{"begin":2769,"end":2880},"obj":"Sentence"},{"id":"T332","span":{"begin":2881,"end":3008},"obj":"Sentence"},{"id":"T333","span":{"begin":3009,"end":3209},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T305","pred":"source","obj":"LitCovid-sentences"},{"subj":"T306","pred":"source","obj":"LitCovid-sentences"},{"subj":"T307","pred":"source","obj":"LitCovid-sentences"},{"subj":"T308","pred":"source","obj":"LitCovid-sentences"},{"subj":"T309","pred":"source","obj":"LitCovid-sentences"},{"subj":"T310","pred":"source","obj":"LitCovid-sentences"},{"subj":"T311","pred":"source","obj":"LitCovid-sentences"},{"subj":"T312","pred":"source","obj":"LitCovid-sentences"},{"subj":"T313","pred":"source","obj":"LitCovid-sentences"},{"subj":"T314","pred":"source","obj":"LitCovid-sentences"},{"subj":"T315","pred":"source","obj":"LitCovid-sentences"},{"subj":"T316","pred":"source","obj":"LitCovid-sentences"},{"subj":"T317","pred":"source","obj":"LitCovid-sentences"},{"subj":"T318","pred":"source","obj":"LitCovid-sentences"},{"subj":"T319","pred":"source","obj":"LitCovid-sentences"},{"subj":"T320","pred":"source","obj":"LitCovid-sentences"},{"subj":"T321","pred":"source","obj":"LitCovid-sentences"},{"subj":"T322","pred":"source","obj":"LitCovid-sentences"},{"subj":"T323","pred":"source","obj":"LitCovid-sentences"},{"subj":"T324","pred":"source","obj":"LitCovid-sentences"},{"subj":"T325","pred":"source","obj":"LitCovid-sentences"},{"subj":"T326","pred":"source","obj":"LitCovid-sentences"},{"subj":"T327","pred":"source","obj":"LitCovid-sentences"},{"subj":"T328","pred":"source","obj":"LitCovid-sentences"},{"subj":"T329","pred":"source","obj":"LitCovid-sentences"},{"subj":"T330","pred":"source","obj":"LitCovid-sentences"},{"subj":"T331","pred":"source","obj":"LitCovid-sentences"},{"subj":"T332","pred":"source","obj":"LitCovid-sentences"},{"subj":"T333","pred":"source","obj":"LitCovid-sentences"}]},{"project":"LitCovid_AGAC","denotations":[{"id":"p84012s24","span":{"begin":2026,"end":2035},"obj":"NegReg"}],"attributes":[{"subj":"p84012s24","pred":"source","obj":"LitCovid_AGAC"}]},{"project":"LitCovid-PubTator","denotations":[{"id":"969","span":{"begin":35,"end":45},"obj":"Species"},{"id":"970","span":{"begin":705,"end":715},"obj":"Species"},{"id":"971","span":{"begin":66,"end":75},"obj":"Disease"},{"id":"972","span":{"begin":158,"end":163},"obj":"Disease"},{"id":"973","span":{"begin":231,"end":240},"obj":"Disease"},{"id":"988","span":{"begin":1603,"end":1611},"obj":"Species"},{"id":"989","span":{"begin":1712,"end":1720},"obj":"Species"},{"id":"990","span":{"begin":1739,"end":1747},"obj":"Species"},{"id":"991","span":{"begin":1766,"end":1776},"obj":"Species"},{"id":"992","span":{"begin":2177,"end":2187},"obj":"Species"},{"id":"993","span":{"begin":2275,"end":2285},"obj":"Species"},{"id":"994","span":{"begin":1821,"end":1832},"obj":"Species"},{"id":"995","span":{"begin":2215,"end":2226},"obj":"Species"},{"id":"996","span":{"begin":2326,"end":2337},"obj":"Species"},{"id":"997","span":{"begin":1620,"end":1625},"obj":"Disease"},{"id":"998","span":{"begin":1629,"end":1649},"obj":"Disease"},{"id":"999","span":{"begin":1748,"end":1756},"obj":"Disease"},{"id":"1000","span":{"begin":1808,"end":1813},"obj":"Disease"},{"id":"1001","span":{"begin":1897,"end":1913},"obj":"Disease"},{"id":"1024","span":{"begin":2457,"end":2467},"obj":"Species"},{"id":"1025","span":{"begin":2538,"end":2553},"obj":"Species"},{"id":"1026","span":{"begin":2576,"end":2586},"obj":"Species"},{"id":"1027","span":{"begin":2588,"end":2615},"obj":"Species"},{"id":"1028","span":{"begin":2617,"end":2627},"obj":"Species"},{"id":"1029","span":{"begin":2629,"end":2650},"obj":"Species"},{"id":"1030","span":{"begin":2652,"end":2668},"obj":"Species"},{"id":"1031","span":{"begin":2670,"end":2686},"obj":"Species"},{"id":"1032","span":{"begin":2699,"end":2720},"obj":"Species"},{"id":"1033","span":{"begin":2773,"end":2781},"obj":"Species"},{"id":"1034","span":{"begin":3039,"end":3047},"obj":"Species"},{"id":"1035","span":{"begin":3150,"end":3160},"obj":"Species"},{"id":"1036","span":{"begin":2511,"end":2527},"obj":"Disease"},{"id":"1037","span":{"begin":2722,"end":2741},"obj":"Disease"},{"id":"1038","span":{"begin":2747,"end":2767},"obj":"Disease"},{"id":"1039","span":{"begin":2853,"end":2879},"obj":"Disease"},{"id":"1040","span":{"begin":2926,"end":2945},"obj":"Disease"},{"id":"1041","span":{"begin":2954,"end":2964},"obj":"Disease"},{"id":"1042","span":{"begin":2966,"end":2981},"obj":"Disease"},{"id":"1043","span":{"begin":2998,"end":3007},"obj":"Disease"},{"id":"1044","span":{"begin":3053,"end":3068},"obj":"Disease"},{"id":"1045","span":{"begin":3171,"end":3186},"obj":"Disease"}],"attributes":[{"id":"A969","pred":"tao:has_database_id","subj":"969","obj":"Tax:2697049"},{"id":"A970","pred":"tao:has_database_id","subj":"970","obj":"Tax:2697049"},{"id":"A971","pred":"tao:has_database_id","subj":"971","obj":"MESH:D011014"},{"id":"A972","pred":"tao:has_database_id","subj":"972","obj":"MESH:D005334"},{"id":"A973","pred":"tao:has_database_id","subj":"973","obj":"MESH:D011014"},{"id":"A988","pred":"tao:has_database_id","subj":"988","obj":"Tax:9606"},{"id":"A989","pred":"tao:has_database_id","subj":"989","obj":"Tax:9606"},{"id":"A990","pred":"tao:has_database_id","subj":"990","obj":"Tax:9606"},{"id":"A991","pred":"tao:has_database_id","subj":"991","obj":"Tax:2697049"},{"id":"A992","pred":"tao:has_database_id","subj":"992","obj":"Tax:2697049"},{"id":"A993","pred":"tao:has_database_id","subj":"993","obj":"Tax:2697049"},{"id":"A994","pred":"tao:has_database_id","subj":"994","obj":"Tax:12814"},{"id":"A995","pred":"tao:has_database_id","subj":"995","obj":"Tax:12814"},{"id":"A996","pred":"tao:has_database_id","subj":"996","obj":"Tax:12814"},{"id":"A997","pred":"tao:has_database_id","subj":"997","obj":"MESH:D005334"},{"id":"A998","pred":"tao:has_database_id","subj":"998","obj":"MESH:D012818"},{"id":"A999","pred":"tao:has_database_id","subj":"999","obj":"MESH:D007239"},{"id":"A1000","pred":"tao:has_database_id","subj":"1000","obj":"MESH:D005334"},{"id":"A1024","pred":"tao:has_database_id","subj":"1024","obj":"Tax:2697049"},{"id":"A1025","pred":"tao:has_database_id","subj":"1025","obj":"Tax:11308"},{"id":"A1026","pred":"tao:has_database_id","subj":"1026","obj":"Tax:10508"},{"id":"A1027","pred":"tao:has_database_id","subj":"1027","obj":"Tax:12814"},{"id":"A1028","pred":"tao:has_database_id","subj":"1028","obj":"Tax:12059"},{"id":"A1029","pred":"tao:has_database_id","subj":"1029","obj":"Tax:162145"},{"id":"A1030","pred":"tao:has_database_id","subj":"1030","obj":"Tax:694009"},{"id":"A1031","pred":"tao:has_database_id","subj":"1031","obj":"Tax:1335626"},{"id":"A1032","pred":"tao:has_database_id","subj":"1032","obj":"Tax:2104"},{"id":"A1033","pred":"tao:has_database_id","subj":"1033","obj":"Tax:9606"},{"id":"A1034","pred":"tao:has_database_id","subj":"1034","obj":"Tax:9606"},{"id":"A1035","pred":"tao:has_database_id","subj":"1035","obj":"Tax:2697049"},{"id":"A1037","pred":"tao:has_database_id","subj":"1037","obj":"MESH:D002690"},{"id":"A1038","pred":"tao:has_database_id","subj":"1038","obj":"MESH:D016920"},{"id":"A1039","pred":"tao:has_database_id","subj":"1039","obj":"MESH:D000072742"},{"id":"A1040","pred":"tao:has_database_id","subj":"1040","obj":"MESH:D003141"},{"id":"A1041","pred":"tao:has_database_id","subj":"1041","obj":"MESH:D014657"},{"id":"A1042","pred":"tao:has_database_id","subj":"1042","obj":"MESH:D003882"},{"id":"A1043","pred":"tao:has_database_id","subj":"1043","obj":"MESH:D011014"},{"id":"A1045","pred":"tao:has_database_id","subj":"1045","obj":"MESH:D001102"},{"subj":"969","pred":"source","obj":"LitCovid-PubTator"},{"subj":"970","pred":"source","obj":"LitCovid-PubTator"},{"subj":"971","pred":"source","obj":"LitCovid-PubTator"},{"subj":"972","pred":"source","obj":"LitCovid-PubTator"},{"subj":"973","pred":"source","obj":"LitCovid-PubTator"},{"subj":"988","pred":"source","obj":"LitCovid-PubTator"},{"subj":"989","pred":"source","obj":"LitCovid-PubTator"},{"subj":"990","pred":"source","obj":"LitCovid-PubTator"},{"subj":"991","pred":"source","obj":"LitCovid-PubTator"},{"subj":"992","pred":"source","obj":"LitCovid-PubTator"},{"subj":"993","pred":"source","obj":"LitCovid-PubTator"},{"subj":"994","pred":"source","obj":"LitCovid-PubTator"},{"subj":"995","pred":"source","obj":"LitCovid-PubTator"},{"subj":"996","pred":"source","obj":"LitCovid-PubTator"},{"subj":"997","pred":"source","obj":"LitCovid-PubTator"},{"subj":"998","pred":"source","obj":"LitCovid-PubTator"},{"subj":"999","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1000","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1001","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1024","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1025","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1026","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1027","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1028","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1029","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1030","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1031","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1032","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1033","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1034","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1035","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1036","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1037","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1038","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1039","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1040","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1041","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1042","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1043","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1044","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1045","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PD-FMA-UBERON","color":"#93b5ec","default":true},{"id":"LitCovid-PD-UBERON","color":"#cfec93"},{"id":"LitCovid-PD-HP","color":"#ec93e9"},{"id":"LitCovid-PD-MONDO","color":"#93ecd4"},{"id":"LitCovid-PD-CLO","color":"#ecba93"},{"id":"LitCovid-PD-CHEBI","color":"#a093ec"},{"id":"LitCovid-PD-GO-BP","color":"#9fec93"},{"id":"LitCovid-sentences","color":"#ec93b9"},{"id":"LitCovid_AGAC","color":"#93d3ec"},{"id":"LitCovid-PubTator","color":"#eceb93"}]}]}}