> top > docs > PMC:7121452 > spans > 17707-18325 > annotations

PMC:7121452 / 17707-18325 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
966 20-30 Species denotes SARS-CoV-2 Tax:2697049
967 57-68 Chemical denotes Aldosterone MESH:D000450
978 253-284 Gene denotes angiotensin-converting enzyme 2 Gene:59272
979 286-290 Gene denotes ACE2 Gene:59272
980 341-345 Gene denotes ACE2 Gene:59272
981 396-410 Gene denotes angiotensin II Gene:183
982 538-541 Gene denotes ACE Gene:1636
983 550-579 Gene denotes angiotensin-converting enzyme Gene:1636
984 107-154 Species denotes severe acute respiratory syndrome coronavirus 2 Tax:2697049
985 156-166 Species denotes SARS-CoV-2 Tax:2697049
986 467-478 Chemical denotes aldosterone MESH:D000450
987 498-509 Disease denotes lung injury MESH:D055370

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T63 173-178 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T64 198-209 Body_part denotes pneumocytes http://purl.org/sig/ont/fma/fma62499
T65 498-502 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T39 498-502 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048

LitCovid_AGAC

Id Subject Object Predicate Lexical cue
p78855s7 333-345 MPA denotes surface ACE2
p78855s17 386-410 MPA denotes unopposed angiotensin II
p78855s20 411-423 PosReg denotes accumulation

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T83 20-28 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T84 107-154 Disease denotes severe acute respiratory syndrome coronavirus 2 http://purl.obolibrary.org/obo/MONDO_0100096
T85 107-140 Disease denotes severe acute respiratory syndrome http://purl.obolibrary.org/obo/MONDO_0005091
T86 156-164 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T87 503-509 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T88 585-588 Disease denotes ARB http://purl.obolibrary.org/obo/MONDO_0012733

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T192 173-178 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T193 431-441 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T194 498-502 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T195 498-502 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T154 45-56 Chemical denotes Angiotensin http://purl.obolibrary.org/obo/CHEBI_2719
T155 57-68 Chemical denotes Aldosterone http://purl.obolibrary.org/obo/CHEBI_27584
T156 195-197 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T157 253-264 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433
T158 396-410 Chemical denotes angiotensin II http://purl.obolibrary.org/obo/CHEBI_2719|http://purl.obolibrary.org/obo/CHEBI_48432|http://purl.obolibrary.org/obo/CHEBI_58506
T161 396-407 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433
T162 408-410 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067
T163 455-466 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433
T164 467-478 Chemical denotes aldosterone http://purl.obolibrary.org/obo/CHEBI_27584|http://purl.obolibrary.org/obo/CHEBI_30834
T166 550-561 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433
T167 589-600 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T10 299-310 http://purl.obolibrary.org/obo/GO_0006897 denotes endocytosis

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T69 77-292 Sentence denotes Shown is the initial entry of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) into cells, primarily type II pneumocytes, after binding to its functional receptor, angiotensin-converting enzyme 2 (ACE2).
T70 293-424 Sentence denotes After endocytosis of the viral complex, surface ACE2 is further down-regulated, resulting in unopposed angiotensin II accumulation.
T71 425-537 Sentence denotes Local activation of the renin–angiotensin–aldosterone system may mediate lung injury responses to viral insults.
T72 538-618 Sentence denotes ACE denotes angiotensin-converting enzyme, and ARB angiotensin-receptor blocker.