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PMC:7115396 / 41346-42349 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T236 90-98 Body_part denotes backbone http://purl.org/sig/ont/fma/fma13478
T237 147-151 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T238 402-408 Body_part denotes tissue http://purl.org/sig/ont/fma/fma9637
T239 440-447 Body_part denotes kidneys http://purl.org/sig/ont/fma/fma7203
T240 452-457 Body_part denotes lungs http://purl.org/sig/ont/fma/fma68877
T241 749-757 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T242 776-781 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T82 402-408 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T83 776-781 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T44 993-1002 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T616 60-62 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T617 144-146 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T618 147-151 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T619 440-447 http://purl.obolibrary.org/obo/UBERON_0002113 denotes kidneys
T620 440-447 http://www.ebi.ac.uk/efo/EFO_0000927 denotes kidneys
T621 440-447 http://www.ebi.ac.uk/efo/EFO_0000929 denotes kidneys
T622 452-457 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lungs
T623 470-477 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animals
T624 511-519 http://purl.obolibrary.org/obo/NCBITaxon_9031 denotes chickens
T625 610-612 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T626 726-734 http://purl.obolibrary.org/obo/NCBITaxon_9031 denotes chickens
T627 800-808 http://purl.obolibrary.org/obo/NCBITaxon_9031 denotes chickens
T628 874-876 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T629 898-899 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T89 749-768 http://purl.obolibrary.org/obo/GO_0002377 denotes antibody production

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T267 0-272 Sentence denotes In conclusion, we constructed the recombinant strain, rH120-S1/YZ, which was based on the backbone of the H120 vaccine strain, and replaced the S1 gene with that of the QX-like nephropathogenic strain, ck/CH/IBYZ/2011, isolated from China using the reverse genetic system.
T268 273-478 Sentence denotes The safety results showed that this recombinant strain was not lethal to one-day-old chicks and it had not gained the ability to tissue invasion or replication in the kidneys and lungs of infected animals.
T269 479-590 Sentence denotes Moreover, the viral load of the chickens was significantly decreased compared with the rH120 and rIBYZ strains.
T270 591-735 Sentence denotes Furthermore, rH120-S1/YZ was found to provide effective protection against challenge with the QX-like nephropathogenic strain in young chickens.
T271 736-861 Sentence denotes The level of antibody production in the serum of the vaccinated chickens detected by ELISA continued to increase after 7 dpi.
T272 862-1003 Sentence denotes Thus, rH120-S1/YZ may be considered a potential live vaccine candidate for protection against Chinese QX-like nephropathogenic IBV infection.

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
606 511-519 Species denotes chickens Tax:9031
607 726-734 Species denotes chickens Tax:9031
608 800-808 Species denotes chickens Tax:9031
609 604-609 Chemical denotes rH120
610 177-193 Disease denotes nephropathogenic
611 461-469 Disease denotes infected MESH:D007239
612 693-709 Disease denotes nephropathogenic
613 972-1002 Disease denotes nephropathogenic IBV infection MESH:D007239