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PMC:7113162 / 125-5770 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
12 74-81 Species denotes Patient Tax:9606
13 124-132 Species denotes patients Tax:9606
14 287-295 Species denotes patients Tax:9606
15 142-150 Disease denotes COVID-19 MESH:C000657245
16 324-332 Disease denotes COVID-19 MESH:C000657245
17 333-342 Disease denotes infection MESH:D007239
18 407-416 Disease denotes infection MESH:D007239
19 529-539 Disease denotes infections MESH:D007239
22 649-656 Species denotes patient Tax:9606
23 756-763 Species denotes patient Tax:9606
25 828-835 Species denotes Patient Tax:9606
29 894-902 Species denotes patients Tax:9606
30 1035-1043 Disease denotes COVID-19 MESH:C000657245
31 1044-1053 Disease denotes infection MESH:D007239
34 1132-1140 Species denotes Patients Tax:9606
35 1257-1264 Species denotes patient Tax:9606
37 2226-2233 Species denotes patient Tax:9606
39 2710-2717 Disease denotes fatigue MESH:D005221
41 4083-4089 Chemical denotes oxygen MESH:D010100
43 4514-4520 Chemical denotes oxygen MESH:D010100
45 4708-4711 Gene denotes zip Gene:1613
47 4822-4825 Gene denotes zip Gene:1613
49 4964-4978 Chemical denotes carbon dioxide MESH:D002245

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T1 3179-3183 Body_part denotes body http://purl.org/sig/ont/fma/fma256135
T2 3221-3225 Body_part denotes face http://purl.org/sig/ont/fma/fma24728
T3 3957-3961 Body_part denotes face http://purl.org/sig/ont/fma/fma24728
T4 4009-4013 Body_part denotes face http://purl.org/sig/ont/fma/fma24728
T5 4480-4484 Body_part denotes face http://purl.org/sig/ont/fma/fma24728
T6 5163-5167 Body_part denotes hand http://purl.org/sig/ont/fma/fma9712
T7 5570-5574 Body_part denotes body http://purl.org/sig/ont/fma/fma256135
T8 5608-5612 Body_part denotes hair http://purl.org/sig/ont/fma/fma53667
T9 5616-5620 Body_part denotes face http://purl.org/sig/ont/fma/fma24728

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 1384-1388 Body_part denotes tube http://purl.obolibrary.org/obo/UBERON_0000025
T2 2130-2134 Body_part denotes tube http://purl.obolibrary.org/obo/UBERON_0000025
T3 3221-3225 Body_part denotes face http://purl.obolibrary.org/obo/UBERON_0001456
T4 3334-3339 Body_part denotes hands http://purl.obolibrary.org/obo/UBERON_0002398
T5 3957-3961 Body_part denotes face http://purl.obolibrary.org/obo/UBERON_0001456
T6 4009-4013 Body_part denotes face http://purl.obolibrary.org/obo/UBERON_0001456
T7 4480-4484 Body_part denotes face http://purl.obolibrary.org/obo/UBERON_0001456
T8 5163-5167 Body_part denotes hand http://purl.obolibrary.org/obo/UBERON_0002398
T9 5536-5541 Body_part denotes hands http://purl.obolibrary.org/obo/UBERON_0002398
T10 5616-5620 Body_part denotes face http://purl.obolibrary.org/obo/UBERON_0001456
T11 5628-5633 Body_part denotes hands http://purl.obolibrary.org/obo/UBERON_0002398

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T1 2710-2717 Phenotype denotes fatigue http://purl.obolibrary.org/obo/HP_0012378

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T4 142-150 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T5 324-332 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T6 333-342 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T7 407-416 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T8 529-539 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T9 1035-1043 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T10 1044-1053 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T1 967-968 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T2 1292-1293 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T3 1320-1321 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T4 1384-1388 http://purl.obolibrary.org/obo/UBERON_0000025 denotes tube
T5 1505-1510 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T6 1552-1553 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T7 1750-1751 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T8 1778-1779 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T9 1976-1977 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T10 2050-2051 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T11 2130-2134 http://purl.obolibrary.org/obo/UBERON_0000025 denotes tube
T12 2844-2847 http://purl.obolibrary.org/obo/CLO_0002807 denotes don
T13 3221-3225 http://purl.obolibrary.org/obo/UBERON_0001456 denotes face
T14 3361-3362 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T15 3607-3608 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T16 3677-3682 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T17 3838-3845 http://purl.obolibrary.org/obo/OBI_0000968 denotes devices
T18 3892-3893 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T19 3957-3961 http://purl.obolibrary.org/obo/UBERON_0001456 denotes face
T20 4009-4013 http://purl.obolibrary.org/obo/UBERON_0001456 denotes face
T21 4214-4219 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T22 4338-4339 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T23 4381-4382 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T24 4396-4402 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airway
T25 4478-4479 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T26 4480-4484 http://purl.obolibrary.org/obo/UBERON_0001456 denotes face
T27 4554-4561 http://purl.obolibrary.org/obo/OBI_0000968 denotes devices
T28 4591-4596 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T29 4664-4670 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airway
T30 5065-5076 http://purl.obolibrary.org/obo/OBI_0000968 denotes instruments
T31 5616-5620 http://purl.obolibrary.org/obo/UBERON_0001456 denotes face

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T1 1961-1972 Chemical denotes application http://purl.obolibrary.org/obo/CHEBI_33232
T2 3640-3657 Chemical denotes local anesthetics http://purl.obolibrary.org/obo/CHEBI_36333
T3 3646-3657 Chemical denotes anesthetics http://purl.obolibrary.org/obo/CHEBI_38867
T4 4083-4089 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T5 4514-4520 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T6 4964-4978 Chemical denotes carbon dioxide http://purl.obolibrary.org/obo/CHEBI_16526
T7 4964-4970 Chemical denotes carbon http://purl.obolibrary.org/obo/CHEBI_27594|http://purl.obolibrary.org/obo/CHEBI_33415

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T1 836-845 http://purl.obolibrary.org/obo/GO_0006810 denotes transport
T2 1389-1397 http://purl.obolibrary.org/obo/GO_0015297 denotes exchange
T3 3975-3984 http://purl.obolibrary.org/obo/GO_0007585 denotes breathing

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T3 0-272 Sentence denotes The following guidelines are based on recommendations from the Anesthesia Patient Safety Foundation (APSF) for working with patients who have COVID-19 [1] and the other literature [2-5], and can be modified and adapted to the circumstances of each institution or hospital.
T4 273-417 Sentence denotes When managing patients with confirmed or suspected COVID-19 infection, it is of utmost importance to protect health care workers from infection.
T5 418-540 Sentence denotes All medical personnel must be provided with personal protective equipment (PPE) to prevent droplet and contact infections.
T6 541-639 Sentence denotes Medical staff and institutions should establish procedural protocols for donning and removing PPE.
T7 640-826 Sentence denotes Prior to patient treatment, staff must identify and review the in-hospital procedural protocols, and plan ahead for patient transfer, anesthesia work environment, and anesthesia methods.
T8 828-878 Sentence denotes Patient transport and operating room managing plan
T9 879-931 Sentence denotes • Do not allow patients to stay in the holding area.
T10 932-1016 Sentence denotes Treatment should be carried out in a pre-allocated negative pressure operating room.
T11 1017-1129 Sentence denotes Warning signs for COVID-19 infection should be posted in front of the operating room to minimize staff exposure.
T12 1130-1205 Sentence denotes • Patients should not stay in the recovery room or postoperative care unit.
T13 1206-1356 Sentence denotes After complete recovery in the operating room, the patient should be transferred into a negative pressure room in a ward or intensive care unit (ICU).
T14 1357-1511 Sentence denotes • Endotracheal intubation, tube exchange, and extubation are high-risk procedures that can expose healthcare workers to respiratory droplets of the virus.
T15 1512-1663 Sentence denotes These procedures must be carried out in a location where negative pressure is applied such as negative pressure room, and special care should be taken.
T16 1664-1848 Sentence denotes • Depending on the clinical situation, performing an endotracheal intubation early in a negative pressure room in a ward or ICU, rather than in an operating room, should be considered.
T17 1849-2047 Sentence denotes • If it is determined that the degree of negative pressure in the environment is not sufficient, the additional application of a portable high-efficiency particulate air filter should be considered.
T18 2048-2244 Sentence denotes • A highly efficient hydrophobic filter should be placed between the endotracheal tube and the reservoir bag, to prevent atmospheric contamination by respiratory droplets during patient transfers.
T19 2246-2264 Sentence denotes Anesthesia Process
T20 2266-2268 Sentence denotes 1.
T21 2269-2292 Sentence denotes Preparation of manpower
T22 2293-2401 Sentence denotes • Assign the most experienced anesthesia professionals to practitioners performing endotracheal intubations.
T23 2402-2490 Sentence denotes Inexperienced trainees should not perform endotracheal intubation for training purposes.
T24 2491-2622 Sentence denotes • Assign experienced assistants who can perform techniques such as cricoid pressure when performing rapid sequence induction (RSI).
T25 2623-2718 Sentence denotes • Consider allowing anesthesia teams to be replaced at least every 2 hours, to prevent fatigue.
T26 2720-2722 Sentence denotes 2.
T27 2723-2793 Sentence denotes Preparation before anesthesia and use of personal protective equipment
T28 2794-2852 Sentence denotes • Allow sufficient time for all staff involved to don PPE.
T29 2853-2906 Sentence denotes It may take more than 5 minutes to properly wear PPE.
T30 2907-2991 Sentence denotes • Early planning and implementation of endotracheal intubation should be considered.
T31 2992-3156 Sentence denotes In the event of an unexpected emergency endotracheal intubation, PPE cannot be adequately donned; therefore, early implementation should be performed when possible.
T32 3157-3294 Sentence denotes • Protective coverall/body suits, N95 masks, disposable goggles/face shields, disposable shoe covers, and disposable gloves must be worn.
T33 3295-3358 Sentence denotes Use the double glove technique on both hands to reduce contact.
T34 3359-3501 Sentence denotes • A powered air-purifying respirator should be worn by healthcare workers who are involved in endotracheal intubation or extubation processes.
T35 3503-3505 Sentence denotes 3.
T36 3506-3539 Sentence denotes Selection of intubation technique
T37 3540-3630 Sentence denotes • Awake fiberoptic intubation should not be performed unless it is a necessary indication.
T38 3631-3706 Sentence denotes Spraying local anesthetics can aerosolize the virus, and should be avoided.
T39 3707-3809 Sentence denotes • Consider using video laryngoscopes to increase the likelihood of successful endotracheal intubation.
T40 3810-3861 Sentence denotes • Consider using disposable devices for intubation.
T41 3863-3865 Sentence denotes 4.
T42 3866-3889 Sentence denotes Endotracheal intubation
T43 3890-4041 Sentence denotes • A high-efficiency hydrophobic filter must be applied between the face mask and the breathing circuit, or between the face mask and the reservoir bag.
T44 4042-4110 Sentence denotes • Preoxygenation for 5 minutes with 100% oxygen should be performed.
T45 4111-4234 Sentence denotes • RSI should be performed to limit procedures such as manual ventilation, which can spread aerosolized virus into the room.
T46 4235-4302 Sentence denotes • The method of RSI can be modified to suit the clinical situation.
T47 4303-4490 Sentence denotes If manual ventilation is required, a small tidal volume may be considered, or a supraglottic airway may be inserted to provide ventilation instead of manual ventilation using a face mask.
T48 4491-4597 Sentence denotes • Do not use high-flow oxygen, such as high-flow nasal cannula devices, as these can aerosolize the virus.
T49 4599-4601 Sentence denotes 5.
T50 4602-4652 Sentence denotes Equipment management after endotracheal intubation
T51 4653-4773 Sentence denotes • All used airway equipment should be placed in double zip-locked plastic bags and removed for disposal or disinfection.
T52 4774-4951 Sentence denotes • Used laryngoscopes should be sealed in double zip-locked plastic bags as soon as the endotracheal intubation is complete, to prevent further contamination of the surroundings.
T53 4952-5021 Sentence denotes • End-tidal carbon dioxide sample lines and traps should be replaced.
T54 5022-5143 Sentence denotes • Take care to avoid contaminating various instruments in the operating room, such as stethoscopes, pens, and telephones.
T55 5145-5147 Sentence denotes 6.
T56 5148-5205 Sentence denotes Undressing and hand washing after endotracheal intubation
T57 5206-5360 Sentence denotes • Consider preparing additional isolation rooms as contaminated areas next to the operating room to remove and dispose of PPE in accordance with protocol.
T58 5361-5523 Sentence denotes If it is difficult to obtain an additional isolation room, use the space inside or immediately outside the operating room to remove PPE according to the protocol.
T59 5524-5561 Sentence denotes • Wash your hands after removing PPE.
T60 5562-5645 Sentence denotes • Avoid body contact, including touching your hair or face, until hands are washed.