PMC:7113162 / 125-5770
Annnotations
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
12 | 74-81 | Species | denotes | Patient | Tax:9606 |
13 | 124-132 | Species | denotes | patients | Tax:9606 |
14 | 287-295 | Species | denotes | patients | Tax:9606 |
15 | 142-150 | Disease | denotes | COVID-19 | MESH:C000657245 |
16 | 324-332 | Disease | denotes | COVID-19 | MESH:C000657245 |
17 | 333-342 | Disease | denotes | infection | MESH:D007239 |
18 | 407-416 | Disease | denotes | infection | MESH:D007239 |
19 | 529-539 | Disease | denotes | infections | MESH:D007239 |
22 | 649-656 | Species | denotes | patient | Tax:9606 |
23 | 756-763 | Species | denotes | patient | Tax:9606 |
25 | 828-835 | Species | denotes | Patient | Tax:9606 |
29 | 894-902 | Species | denotes | patients | Tax:9606 |
30 | 1035-1043 | Disease | denotes | COVID-19 | MESH:C000657245 |
31 | 1044-1053 | Disease | denotes | infection | MESH:D007239 |
34 | 1132-1140 | Species | denotes | Patients | Tax:9606 |
35 | 1257-1264 | Species | denotes | patient | Tax:9606 |
37 | 2226-2233 | Species | denotes | patient | Tax:9606 |
39 | 2710-2717 | Disease | denotes | fatigue | MESH:D005221 |
41 | 4083-4089 | Chemical | denotes | oxygen | MESH:D010100 |
43 | 4514-4520 | Chemical | denotes | oxygen | MESH:D010100 |
45 | 4708-4711 | Gene | denotes | zip | Gene:1613 |
47 | 4822-4825 | Gene | denotes | zip | Gene:1613 |
49 | 4964-4978 | Chemical | denotes | carbon dioxide | MESH:D002245 |
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T1 | 3179-3183 | Body_part | denotes | body | http://purl.org/sig/ont/fma/fma256135 |
T2 | 3221-3225 | Body_part | denotes | face | http://purl.org/sig/ont/fma/fma24728 |
T3 | 3957-3961 | Body_part | denotes | face | http://purl.org/sig/ont/fma/fma24728 |
T4 | 4009-4013 | Body_part | denotes | face | http://purl.org/sig/ont/fma/fma24728 |
T5 | 4480-4484 | Body_part | denotes | face | http://purl.org/sig/ont/fma/fma24728 |
T6 | 5163-5167 | Body_part | denotes | hand | http://purl.org/sig/ont/fma/fma9712 |
T7 | 5570-5574 | Body_part | denotes | body | http://purl.org/sig/ont/fma/fma256135 |
T8 | 5608-5612 | Body_part | denotes | hair | http://purl.org/sig/ont/fma/fma53667 |
T9 | 5616-5620 | Body_part | denotes | face | http://purl.org/sig/ont/fma/fma24728 |
LitCovid-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T1 | 1384-1388 | Body_part | denotes | tube | http://purl.obolibrary.org/obo/UBERON_0000025 |
T2 | 2130-2134 | Body_part | denotes | tube | http://purl.obolibrary.org/obo/UBERON_0000025 |
T3 | 3221-3225 | Body_part | denotes | face | http://purl.obolibrary.org/obo/UBERON_0001456 |
T4 | 3334-3339 | Body_part | denotes | hands | http://purl.obolibrary.org/obo/UBERON_0002398 |
T5 | 3957-3961 | Body_part | denotes | face | http://purl.obolibrary.org/obo/UBERON_0001456 |
T6 | 4009-4013 | Body_part | denotes | face | http://purl.obolibrary.org/obo/UBERON_0001456 |
T7 | 4480-4484 | Body_part | denotes | face | http://purl.obolibrary.org/obo/UBERON_0001456 |
T8 | 5163-5167 | Body_part | denotes | hand | http://purl.obolibrary.org/obo/UBERON_0002398 |
T9 | 5536-5541 | Body_part | denotes | hands | http://purl.obolibrary.org/obo/UBERON_0002398 |
T10 | 5616-5620 | Body_part | denotes | face | http://purl.obolibrary.org/obo/UBERON_0001456 |
T11 | 5628-5633 | Body_part | denotes | hands | http://purl.obolibrary.org/obo/UBERON_0002398 |
LitCovid-PD-HP
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T1 | 2710-2717 | Phenotype | denotes | fatigue | http://purl.obolibrary.org/obo/HP_0012378 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T4 | 142-150 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T5 | 324-332 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T6 | 333-342 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T7 | 407-416 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T8 | 529-539 | Disease | denotes | infections | http://purl.obolibrary.org/obo/MONDO_0005550 |
T9 | 1035-1043 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T10 | 1044-1053 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 967-968 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T2 | 1292-1293 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T3 | 1320-1321 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T4 | 1384-1388 | http://purl.obolibrary.org/obo/UBERON_0000025 | denotes | tube |
T5 | 1505-1510 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T6 | 1552-1553 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T7 | 1750-1751 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T8 | 1778-1779 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T9 | 1976-1977 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T10 | 2050-2051 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T11 | 2130-2134 | http://purl.obolibrary.org/obo/UBERON_0000025 | denotes | tube |
T12 | 2844-2847 | http://purl.obolibrary.org/obo/CLO_0002807 | denotes | don |
T13 | 3221-3225 | http://purl.obolibrary.org/obo/UBERON_0001456 | denotes | face |
T14 | 3361-3362 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T15 | 3607-3608 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T16 | 3677-3682 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T17 | 3838-3845 | http://purl.obolibrary.org/obo/OBI_0000968 | denotes | devices |
T18 | 3892-3893 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T19 | 3957-3961 | http://purl.obolibrary.org/obo/UBERON_0001456 | denotes | face |
T20 | 4009-4013 | http://purl.obolibrary.org/obo/UBERON_0001456 | denotes | face |
T21 | 4214-4219 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T22 | 4338-4339 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T23 | 4381-4382 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T24 | 4396-4402 | http://purl.obolibrary.org/obo/UBERON_0001005 | denotes | airway |
T25 | 4478-4479 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T26 | 4480-4484 | http://purl.obolibrary.org/obo/UBERON_0001456 | denotes | face |
T27 | 4554-4561 | http://purl.obolibrary.org/obo/OBI_0000968 | denotes | devices |
T28 | 4591-4596 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T29 | 4664-4670 | http://purl.obolibrary.org/obo/UBERON_0001005 | denotes | airway |
T30 | 5065-5076 | http://purl.obolibrary.org/obo/OBI_0000968 | denotes | instruments |
T31 | 5616-5620 | http://purl.obolibrary.org/obo/UBERON_0001456 | denotes | face |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T1 | 1961-1972 | Chemical | denotes | application | http://purl.obolibrary.org/obo/CHEBI_33232 |
T2 | 3640-3657 | Chemical | denotes | local anesthetics | http://purl.obolibrary.org/obo/CHEBI_36333 |
T3 | 3646-3657 | Chemical | denotes | anesthetics | http://purl.obolibrary.org/obo/CHEBI_38867 |
T4 | 4083-4089 | Chemical | denotes | oxygen | http://purl.obolibrary.org/obo/CHEBI_25805 |
T5 | 4514-4520 | Chemical | denotes | oxygen | http://purl.obolibrary.org/obo/CHEBI_25805 |
T6 | 4964-4978 | Chemical | denotes | carbon dioxide | http://purl.obolibrary.org/obo/CHEBI_16526 |
T7 | 4964-4970 | Chemical | denotes | carbon | http://purl.obolibrary.org/obo/CHEBI_27594|http://purl.obolibrary.org/obo/CHEBI_33415 |
LitCovid-PD-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 836-845 | http://purl.obolibrary.org/obo/GO_0006810 | denotes | transport |
T2 | 1389-1397 | http://purl.obolibrary.org/obo/GO_0015297 | denotes | exchange |
T3 | 3975-3984 | http://purl.obolibrary.org/obo/GO_0007585 | denotes | breathing |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T3 | 0-272 | Sentence | denotes | The following guidelines are based on recommendations from the Anesthesia Patient Safety Foundation (APSF) for working with patients who have COVID-19 [1] and the other literature [2-5], and can be modified and adapted to the circumstances of each institution or hospital. |
T4 | 273-417 | Sentence | denotes | When managing patients with confirmed or suspected COVID-19 infection, it is of utmost importance to protect health care workers from infection. |
T5 | 418-540 | Sentence | denotes | All medical personnel must be provided with personal protective equipment (PPE) to prevent droplet and contact infections. |
T6 | 541-639 | Sentence | denotes | Medical staff and institutions should establish procedural protocols for donning and removing PPE. |
T7 | 640-826 | Sentence | denotes | Prior to patient treatment, staff must identify and review the in-hospital procedural protocols, and plan ahead for patient transfer, anesthesia work environment, and anesthesia methods. |
T8 | 828-878 | Sentence | denotes | Patient transport and operating room managing plan |
T9 | 879-931 | Sentence | denotes | • Do not allow patients to stay in the holding area. |
T10 | 932-1016 | Sentence | denotes | Treatment should be carried out in a pre-allocated negative pressure operating room. |
T11 | 1017-1129 | Sentence | denotes | Warning signs for COVID-19 infection should be posted in front of the operating room to minimize staff exposure. |
T12 | 1130-1205 | Sentence | denotes | • Patients should not stay in the recovery room or postoperative care unit. |
T13 | 1206-1356 | Sentence | denotes | After complete recovery in the operating room, the patient should be transferred into a negative pressure room in a ward or intensive care unit (ICU). |
T14 | 1357-1511 | Sentence | denotes | • Endotracheal intubation, tube exchange, and extubation are high-risk procedures that can expose healthcare workers to respiratory droplets of the virus. |
T15 | 1512-1663 | Sentence | denotes | These procedures must be carried out in a location where negative pressure is applied such as negative pressure room, and special care should be taken. |
T16 | 1664-1848 | Sentence | denotes | • Depending on the clinical situation, performing an endotracheal intubation early in a negative pressure room in a ward or ICU, rather than in an operating room, should be considered. |
T17 | 1849-2047 | Sentence | denotes | • If it is determined that the degree of negative pressure in the environment is not sufficient, the additional application of a portable high-efficiency particulate air filter should be considered. |
T18 | 2048-2244 | Sentence | denotes | • A highly efficient hydrophobic filter should be placed between the endotracheal tube and the reservoir bag, to prevent atmospheric contamination by respiratory droplets during patient transfers. |
T19 | 2246-2264 | Sentence | denotes | Anesthesia Process |
T20 | 2266-2268 | Sentence | denotes | 1. |
T21 | 2269-2292 | Sentence | denotes | Preparation of manpower |
T22 | 2293-2401 | Sentence | denotes | • Assign the most experienced anesthesia professionals to practitioners performing endotracheal intubations. |
T23 | 2402-2490 | Sentence | denotes | Inexperienced trainees should not perform endotracheal intubation for training purposes. |
T24 | 2491-2622 | Sentence | denotes | • Assign experienced assistants who can perform techniques such as cricoid pressure when performing rapid sequence induction (RSI). |
T25 | 2623-2718 | Sentence | denotes | • Consider allowing anesthesia teams to be replaced at least every 2 hours, to prevent fatigue. |
T26 | 2720-2722 | Sentence | denotes | 2. |
T27 | 2723-2793 | Sentence | denotes | Preparation before anesthesia and use of personal protective equipment |
T28 | 2794-2852 | Sentence | denotes | • Allow sufficient time for all staff involved to don PPE. |
T29 | 2853-2906 | Sentence | denotes | It may take more than 5 minutes to properly wear PPE. |
T30 | 2907-2991 | Sentence | denotes | • Early planning and implementation of endotracheal intubation should be considered. |
T31 | 2992-3156 | Sentence | denotes | In the event of an unexpected emergency endotracheal intubation, PPE cannot be adequately donned; therefore, early implementation should be performed when possible. |
T32 | 3157-3294 | Sentence | denotes | • Protective coverall/body suits, N95 masks, disposable goggles/face shields, disposable shoe covers, and disposable gloves must be worn. |
T33 | 3295-3358 | Sentence | denotes | Use the double glove technique on both hands to reduce contact. |
T34 | 3359-3501 | Sentence | denotes | • A powered air-purifying respirator should be worn by healthcare workers who are involved in endotracheal intubation or extubation processes. |
T35 | 3503-3505 | Sentence | denotes | 3. |
T36 | 3506-3539 | Sentence | denotes | Selection of intubation technique |
T37 | 3540-3630 | Sentence | denotes | • Awake fiberoptic intubation should not be performed unless it is a necessary indication. |
T38 | 3631-3706 | Sentence | denotes | Spraying local anesthetics can aerosolize the virus, and should be avoided. |
T39 | 3707-3809 | Sentence | denotes | • Consider using video laryngoscopes to increase the likelihood of successful endotracheal intubation. |
T40 | 3810-3861 | Sentence | denotes | • Consider using disposable devices for intubation. |
T41 | 3863-3865 | Sentence | denotes | 4. |
T42 | 3866-3889 | Sentence | denotes | Endotracheal intubation |
T43 | 3890-4041 | Sentence | denotes | • A high-efficiency hydrophobic filter must be applied between the face mask and the breathing circuit, or between the face mask and the reservoir bag. |
T44 | 4042-4110 | Sentence | denotes | • Preoxygenation for 5 minutes with 100% oxygen should be performed. |
T45 | 4111-4234 | Sentence | denotes | • RSI should be performed to limit procedures such as manual ventilation, which can spread aerosolized virus into the room. |
T46 | 4235-4302 | Sentence | denotes | • The method of RSI can be modified to suit the clinical situation. |
T47 | 4303-4490 | Sentence | denotes | If manual ventilation is required, a small tidal volume may be considered, or a supraglottic airway may be inserted to provide ventilation instead of manual ventilation using a face mask. |
T48 | 4491-4597 | Sentence | denotes | • Do not use high-flow oxygen, such as high-flow nasal cannula devices, as these can aerosolize the virus. |
T49 | 4599-4601 | Sentence | denotes | 5. |
T50 | 4602-4652 | Sentence | denotes | Equipment management after endotracheal intubation |
T51 | 4653-4773 | Sentence | denotes | • All used airway equipment should be placed in double zip-locked plastic bags and removed for disposal or disinfection. |
T52 | 4774-4951 | Sentence | denotes | • Used laryngoscopes should be sealed in double zip-locked plastic bags as soon as the endotracheal intubation is complete, to prevent further contamination of the surroundings. |
T53 | 4952-5021 | Sentence | denotes | • End-tidal carbon dioxide sample lines and traps should be replaced. |
T54 | 5022-5143 | Sentence | denotes | • Take care to avoid contaminating various instruments in the operating room, such as stethoscopes, pens, and telephones. |
T55 | 5145-5147 | Sentence | denotes | 6. |
T56 | 5148-5205 | Sentence | denotes | Undressing and hand washing after endotracheal intubation |
T57 | 5206-5360 | Sentence | denotes | • Consider preparing additional isolation rooms as contaminated areas next to the operating room to remove and dispose of PPE in accordance with protocol. |
T58 | 5361-5523 | Sentence | denotes | If it is difficult to obtain an additional isolation room, use the space inside or immediately outside the operating room to remove PPE according to the protocol. |
T59 | 5524-5561 | Sentence | denotes | • Wash your hands after removing PPE. |
T60 | 5562-5645 | Sentence | denotes | • Avoid body contact, including touching your hair or face, until hands are washed. |