PMC:7105881 / 43900-44281 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"1392","span":{"begin":39,"end":43},"obj":"Gene"},{"id":"1393","span":{"begin":163,"end":168},"obj":"Gene"},{"id":"1394","span":{"begin":294,"end":299},"obj":"Gene"},{"id":"1409","span":{"begin":199,"end":202},"obj":"Gene"},{"id":"1454","span":{"begin":48,"end":56},"obj":"Species"},{"id":"1455","span":{"begin":157,"end":161},"obj":"Species"},{"id":"1456","span":{"begin":172,"end":176},"obj":"Species"},{"id":"1457","span":{"begin":220,"end":224},"obj":"Species"},{"id":"1458","span":{"begin":238,"end":246},"obj":"Species"},{"id":"1459","span":{"begin":303,"end":307},"obj":"Species"},{"id":"1460","span":{"begin":326,"end":334},"obj":"Species"},{"id":"1501","span":{"begin":5,"end":10},"obj":"Mutation"}],"attributes":[{"id":"A1392","pred":"tao:has_database_id","subj":"1392","obj":"Gene:1803"},{"id":"A1393","pred":"tao:has_database_id","subj":"1393","obj":"Gene:1803"},{"id":"A1394","pred":"tao:has_database_id","subj":"1394","obj":"Gene:1803"},{"id":"A1409","pred":"tao:has_database_id","subj":"1409","obj":"Gene:72935"},{"id":"A1454","pred":"tao:has_database_id","subj":"1454","obj":"Tax:1335626"},{"id":"A1455","pred":"tao:has_database_id","subj":"1455","obj":"Tax:10090"},{"id":"A1456","pred":"tao:has_database_id","subj":"1456","obj":"Tax:10090"},{"id":"A1457","pred":"tao:has_database_id","subj":"1457","obj":"Tax:10090"},{"id":"A1458","pred":"tao:has_database_id","subj":"1458","obj":"Tax:1335626"},{"id":"A1459","pred":"tao:has_database_id","subj":"1459","obj":"Tax:10090"},{"id":"A1460","pred":"tao:has_database_id","subj":"1460","obj":"Tax:1335626"},{"id":"A1501","pred":"tao:has_standard_notation","subj":"1501","obj":"p.T579N"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"RBD (T579N) protein Binds to receptor DPP4 and MERS-CoV RBD-specific neutralizing mAbs (hMS-1, m336, m337, and m338) Montanide; Alum I.M. or S.C. BALB/c mice; hDPP4-Tg mice Elicits neutralizing Abs (\u003e 1:3 × 103) in mice against live MERS-CoV (EMC2012 strain) N/A Protects all vaccinated hDPP4-Tg mice from challenge of MERS-CoV (EMC2012 strain, 104 TCID50) Du et al., 2016a"}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T263","span":{"begin":12,"end":19},"obj":"Body_part"}],"attributes":[{"id":"A263","pred":"fma_id","subj":"T263","obj":"http://purl.org/sig/ont/fma/fma67257"}],"text":"RBD (T579N) protein Binds to receptor DPP4 and MERS-CoV RBD-specific neutralizing mAbs (hMS-1, m336, m337, and m338) Montanide; Alum I.M. or S.C. BALB/c mice; hDPP4-Tg mice Elicits neutralizing Abs (\u003e 1:3 × 103) in mice against live MERS-CoV (EMC2012 strain) N/A Protects all vaccinated hDPP4-Tg mice from challenge of MERS-CoV (EMC2012 strain, 104 TCID50) Du et al., 2016a"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T561","span":{"begin":267,"end":268},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"RBD (T579N) protein Binds to receptor DPP4 and MERS-CoV RBD-specific neutralizing mAbs (hMS-1, m336, m337, and m338) Montanide; Alum I.M. or S.C. BALB/c mice; hDPP4-Tg mice Elicits neutralizing Abs (\u003e 1:3 × 103) in mice against live MERS-CoV (EMC2012 strain) N/A Protects all vaccinated hDPP4-Tg mice from challenge of MERS-CoV (EMC2012 strain, 104 TCID50) Du et al., 2016a"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T288","span":{"begin":12,"end":19},"obj":"Chemical"},{"id":"T289","span":{"begin":169,"end":171},"obj":"Chemical"},{"id":"T290","span":{"begin":300,"end":302},"obj":"Chemical"}],"attributes":[{"id":"A288","pred":"chebi_id","subj":"T288","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A289","pred":"chebi_id","subj":"T289","obj":"http://purl.obolibrary.org/obo/CHEBI_9516"},{"id":"A290","pred":"chebi_id","subj":"T290","obj":"http://purl.obolibrary.org/obo/CHEBI_9516"}],"text":"RBD (T579N) protein Binds to receptor DPP4 and MERS-CoV RBD-specific neutralizing mAbs (hMS-1, m336, m337, and m338) Montanide; Alum I.M. or S.C. BALB/c mice; hDPP4-Tg mice Elicits neutralizing Abs (\u003e 1:3 × 103) in mice against live MERS-CoV (EMC2012 strain) N/A Protects all vaccinated hDPP4-Tg mice from challenge of MERS-CoV (EMC2012 strain, 104 TCID50) Du et al., 2016a"}

{"project":"LitCovid-sentences","denotations":[{"id":"T249","span":{"begin":0,"end":148},"obj":"Sentence"},{"id":"T250","span":{"begin":150,"end":381},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"RBD (T579N) protein Binds to receptor DPP4 and MERS-CoV RBD-specific neutralizing mAbs (hMS-1, m336, m337, and m338) Montanide; Alum I.M. or S.C. BALB/c mice; hDPP4-Tg mice Elicits neutralizing Abs (\u003e 1:3 × 103) in mice against live MERS-CoV (EMC2012 strain) N/A Protects all vaccinated hDPP4-Tg mice from challenge of MERS-CoV (EMC2012 strain, 104 TCID50) Du et al., 2016a"}