PMC:7105881 / 26340-30935
Annnotations
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 893 | 284-287 | Gene | denotes | MPL | Gene:4352 |
| 894 | 961-964 | Gene | denotes | Abs | Gene:51428 |
| 895 | 1012-1016 | Gene | denotes | ACE2 | Gene:70008 |
| 896 | 2178-2183 | Gene | denotes | IFN-γ | Gene:3458 |
| 897 | 2185-2189 | Gene | denotes | IL-2 | Gene:3558 |
| 898 | 2191-2195 | Gene | denotes | IL-4 | Gene:3565 |
| 899 | 2197-2202 | Gene | denotes | IL-10 | Gene:3586 |
| 900 | 3016-3020 | Gene | denotes | IgG1 | Gene:16017 |
| 901 | 3026-3031 | Gene | denotes | IgG2a | Gene:668478 |
| 902 | 3150-3155 | Gene | denotes | IFN-γ | Gene:3458 |
| 903 | 3320-3323 | Gene | denotes | MPL | Gene:4352 |
| 904 | 3824-3829 | Gene | denotes | IFN-γ | Gene:3458 |
| 905 | 3834-3838 | Gene | denotes | IL-4 | Gene:3565 |
| 906 | 4045-4049 | Gene | denotes | IgG1 | Gene:16017 |
| 907 | 4055-4060 | Gene | denotes | IgG2a | Gene:668478 |
| 908 | 4123-4128 | Gene | denotes | IFN-γ | Gene:15978 |
| 909 | 4133-4138 | Gene | denotes | IL-10 | Gene:16153 |
| 910 | 4347-4353 | Gene | denotes | IFN- γ | Gene:3458 |
| 911 | 529-532 | Gene | denotes | MPL | Gene:4352 |
| 912 | 4547-4550 | Gene | denotes | Abs | Gene:51428 |
| 913 | 4273-4276 | Gene | denotes | Abs | Gene:51428 |
| 914 | 4021-4024 | Gene | denotes | Abs | Gene:51428 |
| 915 | 3706-3709 | Gene | denotes | Abs | Gene:51428 |
| 916 | 3379-3382 | Gene | denotes | Abs | Gene:51428 |
| 917 | 3006-3009 | Gene | denotes | Abs | Gene:51428 |
| 918 | 2662-2665 | Gene | denotes | Abs | Gene:51428 |
| 919 | 1959-1962 | Gene | denotes | Abs | Gene:51428 |
| 920 | 1420-1423 | Gene | denotes | Abs | Gene:51428 |
| 921 | 588-591 | Gene | denotes | Abs | Gene:51428 |
| 922 | 341-344 | Gene | denotes | Abs | Gene:51428 |
| 923 | 164-172 | Species | denotes | SARS-CoV | Tax:694009 |
| 924 | 239-247 | Species | denotes | SARS-CoV | Tax:694009 |
| 925 | 308-312 | Species | denotes | mice | Tax:10090 |
| 926 | 321-329 | Species | denotes | SARS-CoV | Tax:694009 |
| 927 | 407-415 | Species | denotes | SARS-CoV | Tax:694009 |
| 928 | 555-559 | Species | denotes | mice | Tax:10090 |
| 929 | 568-576 | Species | denotes | SARS-CoV | Tax:694009 |
| 930 | 610-614 | Species | denotes | mice | Tax:10090 |
| 931 | 678-695 | Species | denotes | SARS-CoV (Urbani | Tax:228330 |
| 932 | 728-732 | Species | denotes | mice | Tax:10090 |
| 933 | 751-767 | Species | denotes | SARS-CoV (Urbani | Tax:228330 |
| 934 | 899-903 | Species | denotes | mice | Tax:10090 |
| 935 | 923-931 | Species | denotes | SARS-CoV | Tax:694009 |
| 936 | 982-986 | Species | denotes | mice | Tax:10090 |
| 937 | 1056-1064 | Species | denotes | SARS-CoV | Tax:694009 |
| 938 | 1150-1166 | Species | denotes | SARS-CoV (Urbani | Tax:228330 |
| 939 | 1300-1308 | Species | denotes | SARS-CoV | Tax:694009 |
| 940 | 1373-1377 | Species | denotes | mice | Tax:10090 |
| 941 | 1379-1386 | Species | denotes | Rabbits | Tax:9986 |
| 942 | 1396-1404 | Species | denotes | SARS-CoV | Tax:694009 |
| 943 | 1433-1437 | Species | denotes | mice | Tax:10090 |
| 944 | 1442-1449 | Species | denotes | rabbits | Tax:9986 |
| 945 | 1477-1484 | Species | denotes | rabbits | Tax:9986 |
| 946 | 1509-1513 | Species | denotes | mice | Tax:10090 |
| 947 | 1526-1533 | Species | denotes | rabbits | Tax:9986 |
| 948 | 1550-1558 | Species | denotes | SARS-CoV | Tax:694009 |
| 949 | 1617-1621 | Species | denotes | mice | Tax:10090 |
| 950 | 1640-1648 | Species | denotes | SARS-CoV | Tax:694009 |
| 951 | 1685-1690 | Species | denotes | mouse | Tax:10090 |
| 952 | 1805-1813 | Species | denotes | SARS-CoV | Tax:694009 |
| 953 | 1924-1928 | Species | denotes | mice | Tax:10090 |
| 954 | 1937-1945 | Species | denotes | SARS-CoV | Tax:694009 |
| 955 | 2098-2106 | Species | denotes | SARS-CoV | Tax:694009 |
| 956 | 2129-2137 | Species | denotes | SARS-CoV | Tax:694009 |
| 957 | 2207-2211 | Species | denotes | mice | Tax:10090 |
| 958 | 2290-2294 | Species | denotes | mice | Tax:10090 |
| 959 | 2313-2321 | Species | denotes | SARS-CoV | Tax:694009 |
| 960 | 2512-2520 | Species | denotes | SARS-CoV | Tax:694009 |
| 961 | 2626-2630 | Species | denotes | mice | Tax:10090 |
| 962 | 2640-2648 | Species | denotes | SARS-CoV | Tax:694009 |
| 963 | 2735-2743 | Species | denotes | SARS-CoV | Tax:694009 |
| 964 | 2788-2792 | Species | denotes | mice | Tax:10090 |
| 965 | 2811-2819 | Species | denotes | SARS-CoV | Tax:694009 |
| 966 | 2974-2978 | Species | denotes | mice | Tax:10090 |
| 967 | 2988-2996 | Species | denotes | SARS-CoV | Tax:694009 |
| 968 | 3036-3040 | Species | denotes | mice | Tax:10090 |
| 969 | 3103-3111 | Species | denotes | SARS-CoV | Tax:694009 |
| 970 | 3160-3164 | Species | denotes | mice | Tax:10090 |
| 971 | 3231-3239 | Species | denotes | SARS-CoV | Tax:694009 |
| 972 | 3346-3350 | Species | denotes | mice | Tax:10090 |
| 973 | 3359-3367 | Species | denotes | SARS-CoV | Tax:694009 |
| 974 | 3401-3405 | Species | denotes | mice | Tax:10090 |
| 975 | 3466-3483 | Species | denotes | SARS-CoV (Urbani | Tax:228330 |
| 976 | 3516-3520 | Species | denotes | mice | Tax:10090 |
| 977 | 3539-3555 | Species | denotes | SARS-CoV (Urbani | Tax:228330 |
| 978 | 3671-3675 | Species | denotes | mice | Tax:10090 |
| 979 | 3685-3693 | Species | denotes | SARS-CoV | Tax:694009 |
| 980 | 3732-3736 | Species | denotes | mice | Tax:10090 |
| 981 | 3776-3784 | Species | denotes | SARS-CoV | Tax:694009 |
| 982 | 3843-3847 | Species | denotes | mice | Tax:10090 |
| 983 | 3897-3905 | Species | denotes | SARS-CoV | Tax:694009 |
| 984 | 3987-3991 | Species | denotes | mice | Tax:10090 |
| 985 | 4001-4009 | Species | denotes | SARS-CoV | Tax:694009 |
| 986 | 4065-4069 | Species | denotes | mice | Tax:10090 |
| 987 | 4152-4156 | Species | denotes | mice | Tax:10090 |
| 988 | 4239-4243 | Species | denotes | mice | Tax:10090 |
| 989 | 4253-4261 | Species | denotes | SARS-CoV | Tax:694009 |
| 990 | 4286-4290 | Species | denotes | mice | Tax:10090 |
| 991 | 4300-4308 | Species | denotes | SARS-CoV | Tax:694009 |
| 992 | 4358-4362 | Species | denotes | mice | Tax:10090 |
| 993 | 4438-4446 | Species | denotes | patients | Tax:9606 |
| 994 | 4460-4464 | Species | denotes | mice | Tax:10090 |
| 995 | 4469-4476 | Species | denotes | rabbits | Tax:9986 |
| 996 | 4501-4505 | Species | denotes | mice | Tax:10090 |
| 997 | 4511-4518 | Species | denotes | rabbits | Tax:9986 |
| 998 | 4527-4535 | Species | denotes | SARS-CoV | Tax:694009 |
| 999 | 4560-4570 | Disease | denotes | rabbits N | MESH:D001480 |
| 1000 | 216-220 | CellLine | denotes | EC-S | CVCL:5V07 |
| 1001 | 1560-1564 | CellLine | denotes | BJ01 | CVCL:6573 |
| 1002 | 1650-1654 | CellLine | denotes | BJ01 | CVCL:6573 |
| 1003 | 1770-1773 | CellLine | denotes | CHO | CVCL:0213 |
| 1004 | 1782-1785 | CellLine | denotes | CHO | CVCL:0213 |
| 1005 | 1896-1898 | CellLine | denotes | H9 | CVCL:1240 |
| 1006 | 2009-2012 | CellLine | denotes | CHO | CVCL:0213 |
| 1007 | 2030-2040 | CellLine | denotes | RBD219-CHO | CVCL:G580 |
| 1008 | 2071-2074 | CellLine | denotes | CHO | CVCL:0213 |
| 1009 | 2086-2096 | CellLine | denotes | RBD219-CHO | CVCL:G580 |
| 1010 | 2230-2240 | CellLine | denotes | RBD219-CHO | CVCL:G580 |
| 1011 | 2271-2274 | CellLine | denotes | CHO | CVCL:0213 |
| 1012 | 2358-2361 | CellLine | denotes | CHO | CVCL:0213 |
| 1013 | 2382-2392 | CellLine | denotes | RBD219-CHO | CVCL:G580 |
| 1014 | 2489-2493 | CellLine | denotes | 293T | CVCL:0063 |
| 1015 | 2603-2605 | CellLine | denotes | H9 | CVCL:1240 |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T115 | 70-78 | Body_part | denotes | Antibody | http://purl.org/sig/ont/fma/fma62871 |
| T116 | 199-206 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T117 | 221-229 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T118 | 346-349 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
| T119 | 488-496 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T120 | 593-596 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
| T121 | 820-825 | Body_part | denotes | lungs | http://purl.org/sig/ont/fma/fma68877 |
| T122 | 852-859 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T123 | 955-960 | Body_part | denotes | serum | http://purl.org/sig/ont/fma/fma63083 |
| T124 | 966-969 | Body_part | denotes | IgA | http://purl.org/sig/ont/fma/fma62874 |
| T125 | 974-977 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
| T126 | 1230-1235 | Body_part | denotes | lungs | http://purl.org/sig/ont/fma/fma68877 |
| T127 | 1313-1320 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T128 | 1328-1335 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T129 | 1425-1428 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
| T130 | 1704-1712 | Body_part | denotes | alveolar | http://purl.org/sig/ont/fma/fma264783 |
| T131 | 1723-1728 | Body_part | denotes | lungs | http://purl.org/sig/ont/fma/fma68877 |
| T132 | 1786-1794 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T133 | 2185-2189 | Body_part | denotes | IL-2 | http://purl.org/sig/ont/fma/fma84051 |
| T134 | 2418-2421 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T135 | 2455-2460 | Body_part | denotes | lungs | http://purl.org/sig/ont/fma/fma68877 |
| T136 | 2494-2501 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T137 | 2667-2670 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
| T138 | 2870-2873 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T139 | 2892-2897 | Body_part | denotes | lungs | http://purl.org/sig/ont/fma/fma68877 |
| T140 | 2925-2932 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T141 | 3011-3014 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
| T142 | 3242-3249 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T143 | 3277-3285 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T144 | 3384-3387 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
| T145 | 3608-3613 | Body_part | denotes | lungs | http://purl.org/sig/ont/fma/fma68877 |
| T146 | 3634-3641 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T147 | 3711-3714 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
| T148 | 3923-3931 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T149 | 3950-3957 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T150 | 4026-4029 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
| T151 | 4139-4148 | Body_part | denotes | cytokines | http://purl.org/sig/ont/fma/fma84050 |
| T152 | 4185-4192 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T153 | 4278-4281 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
| T154 | 4552-4555 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T11 | 955-960 | Body_part | denotes | serum | http://purl.obolibrary.org/obo/UBERON_0001977 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T115 | 164-172 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T116 | 239-247 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T117 | 252-255 | Disease | denotes | NTD | http://purl.obolibrary.org/obo/MONDO_0008449|http://purl.obolibrary.org/obo/MONDO_0018075 |
| T119 | 321-329 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T120 | 407-415 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T121 | 568-576 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T122 | 678-686 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T123 | 751-759 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T124 | 923-931 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T125 | 1056-1064 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T126 | 1093-1096 | Disease | denotes | ADE | http://purl.obolibrary.org/obo/MONDO_0019383 |
| T127 | 1150-1158 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T128 | 1300-1308 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T129 | 1396-1404 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T130 | 1550-1558 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T131 | 1640-1648 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T132 | 1805-1813 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T133 | 1937-1945 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T134 | 2098-2106 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T135 | 2129-2137 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T136 | 2313-2321 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T137 | 2512-2520 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T138 | 2640-2648 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T139 | 2735-2743 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T140 | 2811-2819 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T141 | 2988-2996 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T142 | 3103-3111 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T143 | 3231-3239 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T144 | 3359-3367 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T145 | 3466-3474 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T146 | 3539-3547 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T147 | 3685-3693 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T148 | 3776-3784 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T149 | 3897-3905 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T150 | 4001-4009 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T151 | 4253-4261 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T152 | 4300-4308 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T153 | 4433-4437 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T154 | 4527-4535 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T274 | 55-61 | http://purl.obolibrary.org/obo/NCBITaxon_33208 | denotes | Animal |
| T275 | 207-209 | http://purl.obolibrary.org/obo/CLO_0003358 | denotes | FL |
| T276 | 216-218 | http://purl.obolibrary.org/obo/CLO_0002878 | denotes | EC |
| T277 | 248-250 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
| T278 | 266-268 | http://purl.obolibrary.org/obo/CLO_0008922 | denotes | S2 |
| T279 | 266-268 | http://purl.obolibrary.org/obo/CLO_0050052 | denotes | S2 |
| T280 | 449-450 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T281 | 454-455 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T282 | 500-501 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T283 | 637-640 | http://purl.obolibrary.org/obo/CLO_0054060 | denotes | 102 |
| T284 | 645-650 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S; ∼1 |
| T285 | 655-658 | http://purl.obolibrary.org/obo/CLO_0054060 | denotes | 102 |
| T286 | 706-707 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T287 | 820-825 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lungs |
| T288 | 827-829 | http://purl.obolibrary.org/obo/CLO_0001022 | denotes | Li |
| T289 | 827-829 | http://purl.obolibrary.org/obo/CLO_0007314 | denotes | Li |
| T290 | 863-864 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T291 | 905-913 | http://purl.obolibrary.org/obo/NCBITaxon_10026 | denotes | Hamsters |
| T292 | 991-999 | http://purl.obolibrary.org/obo/NCBITaxon_10026 | denotes | hamsters |
| T293 | 1100-1101 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T294 | 1123-1131 | http://purl.obolibrary.org/obo/NCBITaxon_10026 | denotes | hamsters |
| T295 | 1230-1235 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lungs |
| T296 | 1325-1327 | http://purl.obolibrary.org/obo/CLO_0052676 | denotes | Fc |
| T297 | 1339-1340 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T298 | 1576-1577 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T299 | 1598-1601 | http://purl.obolibrary.org/obo/CLO_0053799 | denotes | 4/5 |
| T300 | 1685-1690 | http://purl.obolibrary.org/obo/CLO_0007836 | denotes | mouse |
| T301 | 1723-1728 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lungs |
| T302 | 1770-1773 | http://purl.obolibrary.org/obo/CLO_0002421 | denotes | CHO |
| T303 | 1770-1773 | http://purl.obolibrary.org/obo/CLO_0052479 | denotes | CHO |
| T304 | 1770-1773 | http://purl.obolibrary.org/obo/CLO_0052480 | denotes | CHO |
| T305 | 1770-1773 | http://purl.obolibrary.org/obo/CLO_0052483 | denotes | CHO |
| T306 | 1770-1773 | http://purl.obolibrary.org/obo/CLO_0052484 | denotes | CHO |
| T307 | 1770-1773 | http://purl.obolibrary.org/obo/CLO_0052485 | denotes | CHO |
| T308 | 1782-1785 | http://purl.obolibrary.org/obo/CLO_0002421 | denotes | CHO |
| T309 | 1782-1785 | http://purl.obolibrary.org/obo/CLO_0052479 | denotes | CHO |
| T310 | 1782-1785 | http://purl.obolibrary.org/obo/CLO_0052480 | denotes | CHO |
| T311 | 1782-1785 | http://purl.obolibrary.org/obo/CLO_0052483 | denotes | CHO |
| T312 | 1782-1785 | http://purl.obolibrary.org/obo/CLO_0052484 | denotes | CHO |
| T313 | 1782-1785 | http://purl.obolibrary.org/obo/CLO_0052485 | denotes | CHO |
| T314 | 2009-2012 | http://purl.obolibrary.org/obo/CLO_0002421 | denotes | CHO |
| T315 | 2009-2012 | http://purl.obolibrary.org/obo/CLO_0052479 | denotes | CHO |
| T316 | 2009-2012 | http://purl.obolibrary.org/obo/CLO_0052480 | denotes | CHO |
| T317 | 2009-2012 | http://purl.obolibrary.org/obo/CLO_0052483 | denotes | CHO |
| T318 | 2009-2012 | http://purl.obolibrary.org/obo/CLO_0052484 | denotes | CHO |
| T319 | 2009-2012 | http://purl.obolibrary.org/obo/CLO_0052485 | denotes | CHO |
| T320 | 2037-2040 | http://purl.obolibrary.org/obo/CLO_0002421 | denotes | CHO |
| T321 | 2037-2040 | http://purl.obolibrary.org/obo/CLO_0052479 | denotes | CHO |
| T322 | 2037-2040 | http://purl.obolibrary.org/obo/CLO_0052480 | denotes | CHO |
| T323 | 2037-2040 | http://purl.obolibrary.org/obo/CLO_0052483 | denotes | CHO |
| T324 | 2037-2040 | http://purl.obolibrary.org/obo/CLO_0052484 | denotes | CHO |
| T325 | 2037-2040 | http://purl.obolibrary.org/obo/CLO_0052485 | denotes | CHO |
| T326 | 2071-2074 | http://purl.obolibrary.org/obo/CLO_0002421 | denotes | CHO |
| T327 | 2071-2074 | http://purl.obolibrary.org/obo/CLO_0052479 | denotes | CHO |
| T328 | 2071-2074 | http://purl.obolibrary.org/obo/CLO_0052480 | denotes | CHO |
| T329 | 2071-2074 | http://purl.obolibrary.org/obo/CLO_0052483 | denotes | CHO |
| T330 | 2071-2074 | http://purl.obolibrary.org/obo/CLO_0052484 | denotes | CHO |
| T331 | 2071-2074 | http://purl.obolibrary.org/obo/CLO_0052485 | denotes | CHO |
| T332 | 2093-2096 | http://purl.obolibrary.org/obo/CLO_0002421 | denotes | CHO |
| T333 | 2093-2096 | http://purl.obolibrary.org/obo/CLO_0052479 | denotes | CHO |
| T334 | 2093-2096 | http://purl.obolibrary.org/obo/CLO_0052480 | denotes | CHO |
| T335 | 2093-2096 | http://purl.obolibrary.org/obo/CLO_0052483 | denotes | CHO |
| T336 | 2093-2096 | http://purl.obolibrary.org/obo/CLO_0052484 | denotes | CHO |
| T337 | 2093-2096 | http://purl.obolibrary.org/obo/CLO_0052485 | denotes | CHO |
| T338 | 2185-2189 | http://purl.obolibrary.org/obo/PR_000001379 | denotes | IL-2 |
| T339 | 2237-2240 | http://purl.obolibrary.org/obo/CLO_0002421 | denotes | CHO |
| T340 | 2237-2240 | http://purl.obolibrary.org/obo/CLO_0052479 | denotes | CHO |
| T341 | 2237-2240 | http://purl.obolibrary.org/obo/CLO_0052480 | denotes | CHO |
| T342 | 2237-2240 | http://purl.obolibrary.org/obo/CLO_0052483 | denotes | CHO |
| T343 | 2237-2240 | http://purl.obolibrary.org/obo/CLO_0052484 | denotes | CHO |
| T344 | 2237-2240 | http://purl.obolibrary.org/obo/CLO_0052485 | denotes | CHO |
| T345 | 2255-2258 | http://purl.obolibrary.org/obo/CLO_0001000 | denotes | 3/5 |
| T346 | 2271-2274 | http://purl.obolibrary.org/obo/CLO_0002421 | denotes | CHO |
| T347 | 2271-2274 | http://purl.obolibrary.org/obo/CLO_0052479 | denotes | CHO |
| T348 | 2271-2274 | http://purl.obolibrary.org/obo/CLO_0052480 | denotes | CHO |
| T349 | 2271-2274 | http://purl.obolibrary.org/obo/CLO_0052483 | denotes | CHO |
| T350 | 2271-2274 | http://purl.obolibrary.org/obo/CLO_0052484 | denotes | CHO |
| T351 | 2271-2274 | http://purl.obolibrary.org/obo/CLO_0052485 | denotes | CHO |
| T352 | 2358-2361 | http://purl.obolibrary.org/obo/CLO_0002421 | denotes | CHO |
| T353 | 2358-2361 | http://purl.obolibrary.org/obo/CLO_0052479 | denotes | CHO |
| T354 | 2358-2361 | http://purl.obolibrary.org/obo/CLO_0052480 | denotes | CHO |
| T355 | 2358-2361 | http://purl.obolibrary.org/obo/CLO_0052483 | denotes | CHO |
| T356 | 2358-2361 | http://purl.obolibrary.org/obo/CLO_0052484 | denotes | CHO |
| T357 | 2358-2361 | http://purl.obolibrary.org/obo/CLO_0052485 | denotes | CHO |
| T358 | 2389-2392 | http://purl.obolibrary.org/obo/CLO_0002421 | denotes | CHO |
| T359 | 2389-2392 | http://purl.obolibrary.org/obo/CLO_0052479 | denotes | CHO |
| T360 | 2389-2392 | http://purl.obolibrary.org/obo/CLO_0052480 | denotes | CHO |
| T361 | 2389-2392 | http://purl.obolibrary.org/obo/CLO_0052483 | denotes | CHO |
| T362 | 2389-2392 | http://purl.obolibrary.org/obo/CLO_0052484 | denotes | CHO |
| T363 | 2389-2392 | http://purl.obolibrary.org/obo/CLO_0052485 | denotes | CHO |
| T364 | 2455-2460 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lungs |
| T365 | 2489-2493 | http://purl.obolibrary.org/obo/CLO_0050894 | denotes | 293T |
| T366 | 2489-2493 | http://purl.obolibrary.org/obo/CLO_0051650 | denotes | 293T |
| T367 | 2489-2493 | http://purl.obolibrary.org/obo/CLO_0052052 | denotes | 293T |
| T368 | 2608-2611 | http://purl.obolibrary.org/obo/CLO_0051568 | denotes | SAS |
| T369 | 2761-2762 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T370 | 2892-2897 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lungs |
| T371 | 2936-2937 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T372 | 3168-3169 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T373 | 3260-3262 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
| T374 | 3267-3269 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
| T375 | 3289-3290 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T376 | 3429-3432 | http://purl.obolibrary.org/obo/CLO_0054060 | denotes | 102 |
| T377 | 3437-3439 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
| T378 | 3450-3452 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
| T379 | 3494-3495 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T380 | 3608-3613 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lungs |
| T381 | 3615-3617 | http://purl.obolibrary.org/obo/CLO_0001022 | denotes | Li |
| T382 | 3615-3617 | http://purl.obolibrary.org/obo/CLO_0007314 | denotes | Li |
| T383 | 3631-3633 | http://purl.obolibrary.org/obo/CLO_0008922 | denotes | S2 |
| T384 | 3631-3633 | http://purl.obolibrary.org/obo/CLO_0050052 | denotes | S2 |
| T385 | 3645-3646 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T386 | 3694-3696 | http://purl.obolibrary.org/obo/CLO_0008922 | denotes | S2 |
| T387 | 3694-3696 | http://purl.obolibrary.org/obo/CLO_0050052 | denotes | S2 |
| T388 | 3758-3766 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T389 | 3785-3787 | http://purl.obolibrary.org/obo/CLO_0008922 | denotes | S2 |
| T390 | 3785-3787 | http://purl.obolibrary.org/obo/CLO_0050052 | denotes | S2 |
| T391 | 3851-3852 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T392 | 3961-3962 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T393 | 4160-4161 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T394 | 4196-4197 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T395 | 4366-4367 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T396 | 4386-4388 | http://purl.obolibrary.org/obo/CLO_0007448 | denotes | M1 |
| T397 | 4386-4388 | http://purl.obolibrary.org/obo/CLO_0050175 | denotes | M1 |
| T398 | 4405-4413 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptides |
| T399 | 4571-4572 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T400 | 4576-4577 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T121 | 199-206 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T122 | 207-209 | Chemical | denotes | FL | http://purl.obolibrary.org/obo/CHEBI_91150 |
| T123 | 221-229 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T124 | 266-268 | Chemical | denotes | S2 | http://purl.obolibrary.org/obo/CHEBI_29387 |
| T125 | 488-496 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T126 | 512-516 | Chemical | denotes | Gold | http://purl.obolibrary.org/obo/CHEBI_29287 |
| T127 | 827-829 | Chemical | denotes | Li | http://purl.obolibrary.org/obo/CHEBI_30145 |
| T128 | 852-859 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T129 | 1313-1320 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T130 | 1328-1335 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T131 | 1786-1794 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T132 | 2185-2187 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T134 | 2191-2193 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T136 | 2197-2199 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T138 | 2494-2501 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T139 | 2925-2932 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T140 | 3242-3249 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T141 | 3277-3285 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T142 | 3301-3305 | Chemical | denotes | Gold | http://purl.obolibrary.org/obo/CHEBI_29287 |
| T143 | 3615-3617 | Chemical | denotes | Li | http://purl.obolibrary.org/obo/CHEBI_30145 |
| T144 | 3631-3633 | Chemical | denotes | S2 | http://purl.obolibrary.org/obo/CHEBI_29387 |
| T145 | 3634-3641 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T146 | 3694-3696 | Chemical | denotes | S2 | http://purl.obolibrary.org/obo/CHEBI_29387 |
| T147 | 3785-3787 | Chemical | denotes | S2 | http://purl.obolibrary.org/obo/CHEBI_29387 |
| T148 | 3834-3836 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T150 | 3854-3857 | Chemical | denotes | Guo | http://purl.obolibrary.org/obo/CHEBI_16750 |
| T151 | 3923-3931 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T152 | 3950-3957 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T153 | 4133-4135 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T155 | 4185-4192 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T156 | 4386-4388 | Chemical | denotes | M1 | http://purl.obolibrary.org/obo/CHEBI_51079|http://purl.obolibrary.org/obo/CHEBI_139019|http://purl.obolibrary.org/obo/CHEBI_140152|http://purl.obolibrary.org/obo/CHEBI_34826 |
| T160 | 4405-4413 | Chemical | denotes | peptides | http://purl.obolibrary.org/obo/CHEBI_16670 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T46 | 89-113 | http://purl.obolibrary.org/obo/GO_0002456 | denotes | Cellular immune response |
| T47 | 89-113 | http://purl.obolibrary.org/obo/GO_0002449 | denotes | Cellular immune response |
| T48 | 89-113 | http://purl.obolibrary.org/obo/GO_0002443 | denotes | Cellular immune response |
| T49 | 98-113 | http://purl.obolibrary.org/obo/GO_0006955 | denotes | immune response |
| T50 | 2151-2176 | http://purl.obolibrary.org/obo/GO_0002456 | denotes | cellular immune responses |
| T51 | 2151-2176 | http://purl.obolibrary.org/obo/GO_0002449 | denotes | cellular immune responses |
| T52 | 2151-2176 | http://purl.obolibrary.org/obo/GO_0002443 | denotes | cellular immune responses |
| T53 | 3080-3093 | http://purl.obolibrary.org/obo/GO_0070085 | denotes | glycosylation |
| T54 | 3123-3148 | http://purl.obolibrary.org/obo/GO_0002456 | denotes | cellular immune responses |
| T55 | 3123-3148 | http://purl.obolibrary.org/obo/GO_0002449 | denotes | cellular immune responses |
| T56 | 3123-3148 | http://purl.obolibrary.org/obo/GO_0002443 | denotes | cellular immune responses |
| T57 | 3797-3822 | http://purl.obolibrary.org/obo/GO_0002456 | denotes | cellular immune responses |
| T58 | 3797-3822 | http://purl.obolibrary.org/obo/GO_0002449 | denotes | cellular immune responses |
| T59 | 3797-3822 | http://purl.obolibrary.org/obo/GO_0002443 | denotes | cellular immune responses |
| T60 | 4079-4104 | http://purl.obolibrary.org/obo/GO_0002456 | denotes | cellular immune responses |
| T61 | 4079-4104 | http://purl.obolibrary.org/obo/GO_0002449 | denotes | cellular immune responses |
| T62 | 4079-4104 | http://purl.obolibrary.org/obo/GO_0002443 | denotes | cellular immune responses |
| T63 | 4320-4345 | http://purl.obolibrary.org/obo/GO_0002456 | denotes | cellular immune responses |
| T64 | 4320-4345 | http://purl.obolibrary.org/obo/GO_0002449 | denotes | cellular immune responses |
| T65 | 4320-4345 | http://purl.obolibrary.org/obo/GO_0002443 | denotes | cellular immune responses |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32265848-23573979-36511114 | 838-842 | 23573979 | denotes | 2013 |
| 32265848-17049691-36511115 | 1249-1253 | 17049691 | denotes | 2007 |
| 32265848-22311359-36511116 | 1269-1273 | 22311359 | denotes | 2012 |
| 32265848-15474494-36511117 | 1741-1745 | 15474494 | denotes | 2004 |
| 32265848-17092615-36511118 | 1758-1762 | 17092615 | denotes | 2007 |
| 32265848-20374001-36511120 | 2480-2484 | 20374001 | denotes | 2010 |
| 32265848-16919855-36511122 | 3192-3196 | 16919855 | denotes | 2007 |
| 32265848-23573979-36511123 | 3626-3630 | 23573979 | denotes | 2013 |
| 32265848-16101349-36511124 | 3866-3870 | 16101349 | denotes | 2005 |
| 32265848-19523911-36511125 | 4177-4181 | 19523911 | denotes | 2009 |
| 32265848-16494977-36511126 | 4381-4385 | 16494977 | denotes | 2006 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T158 | 0-137 | Sentence | denotes | Name Antigenicity and functionality Adjuvant Route Animal models Antibody response Cellular immune response Protection References |
| T159 | 138-206 | Sentence | denotes | Subunit vaccines based on SARS-CoV full-length or trimeric S protein |
| T160 | 207-299 | Sentence | denotes | FL-S and EC-S proteins Bind to SARS-CoV S1, NTD, RBD, and S2-specific mAbs MPL + TDM S.C. |
| T161 | 301-355 | Sentence | denotes | BALB/c mice Elicit SARS-CoV S-specific Abs (IgG, > 1: |
| T162 | 356-473 | Sentence | denotes | 2 × 105), neutralizing (> 1:2.4 × 104) pseudotyped SARS-CoV (Tor2, GD03, and SZ3 strains) N/A N/A He et al., 2006a |
| T163 | 474-546 | Sentence | denotes | S andS-foldon proteins N/A TiterMax Gold; Alum Hydro+MPL S.C. or I.M. |
| T164 | 548-842 | Sentence | denotes | BALB/c mice Elicit SARS-CoV S-specific Abs (IgG, > 1:104) in mice, neutralizing (∼2.4 × 102 for S; ∼1:7 × 102 for S-foldon) live SARS-CoV (Urbani strain) N/A Protect vaccinated mice from challenge of SARS-CoV (Urbani strain, 105 TCID50) with undetectable viral load in lungs Li et al., 2013 |
| T165 | 843-890 | Sentence | denotes | triSpike protein N/A Alum hydro I.P. or S.C. |
| T166 | 892-1273 | Sentence | denotes | BALB/c mice; Hamsters Elicits SARS-CoV S-specific mucosal and serum Abs (IgA and IgG) in mice and hamsters, blocking S-ACE2 receptor binding and neutralizing live SARS-CoV (HKU-39849 strain); induces ADE N/A Protects vaccinated hamsters from challenge of SARS-CoV (Urbani strain, 103 TCID50) with undetectable or reduced viral load in lungs Kam et al., 2007; Jaume et al., 2012 |
| T167 | 1274-1320 | Sentence | denotes | Subunit vaccines based on SARS-CoV RBD protein |
| T168 | 1321-1364 | Sentence | denotes | RBD-Fc protein N/A Freund’s I.D. or I.M. |
| T169 | 1366-1514 | Sentence | denotes | BALB/c mice; Rabbits Elicits SARS-CoV S/RBD-specific Abs (IgG) in mice and rabbits, neutralizing pseudotyped (rabbits: ≥ 7.3 × 104) and live (mice: |
| T170 | 1515-1762 | Sentence | denotes | 1:4 × 103; rabbits: > 1:1.5 × 104) SARS-CoV (BJ01 strain) N/A Protects majority (4/5) of vaccinated mice from challenge of SARS-CoV (BJ01 strain, 106 TCID50), with one mouse showing mild alveolar damage in lungs He et al., 2004; Du et al., 2007 |
| T171 | 1763-1915 | Sentence | denotes | RBD193-CHO; RBD219-CHO proteins Binds to SARS-CoV RBD-specific mAbs (neutralizing 24H8, 31H12, 35B5, 33G4, 19B2; non-neutralizing 17H9) Freund’s S.C. |
| T172 | 1917-2484 | Sentence | denotes | BALB/c mice Elicit SARS-CoV RBD-specific Abs, neutralizing pseudotyped (< 1:104 for RBD193-CHO; 1:5.8 × 104 for RBD219-CHO) and live (< 1:103 for RBD193-CHO; 1:103 for RBD219-CHO) SARS-CoV (GZ50 strain) Induce SARS-CoV RBD-specific cellular immune responses (IFN-γ, IL-2, IL-4, IL-10) in mice Protect all (for RBD219-CHO) or majority (3/5, for RBD219-CHO) of vaccinated mice from challenge of SARS-CoV (GZ50 strain, 100 TCID50 for RBD193-CHO; 5 × 105 TCID50 for RBD219-CHO) with undetectable viral RNA or no, to reduced, viral load in lungs Du et al., 2009c, 2010 |
| T173 | 2485-2617 | Sentence | denotes | RBD-293T protein Binds to SARS-CoV RBD-specific mAbs (neutralizing 24H8, 31H12, 35B5, 33G4, 19B2; non-neutralizing 17H9) SAS S.C. |
| T174 | 2619-2915 | Sentence | denotes | BALB/c mice Elicits SARS-CoV RBD-specific Abs (IgG), neutralizing pseudotyped (1:6.9 × 105) and live (1:1.6 × 103) SARS-CoV (GZ50 strain) N/A Protects all vaccinated mice from challenge of SARS-CoV (GZ50 strain, 100 TCID50) with undetectable viral RNA and viral load in lungs Du et al., 2009b |
| T175 | 2916-2961 | Sentence | denotes | S318-510 protein N/A Alum; Alum + CpG S.C. |
| T176 | 2963-3041 | Sentence | denotes | 129S6/SvEv mice Elicits SARS-CoV-specific Abs (IgG, IgG1, and IgG2a) in mice. |
| T177 | 3042-3196 | Sentence | denotes | Reduces neutralization after removing glycosylation Induces SARS-CoV S-specific cellular immune responses (IFN-γ) in mice N/A Zakhartchouk et al., 2007 |
| T178 | 3197-3259 | Sentence | denotes | Subunit vaccines based on non-RBD SARS-CoV S protein fragments |
| T179 | 3260-3337 | Sentence | denotes | S1 and S1-foldon proteins N/A TiterMax Gold; Alum Hydro + MPL S.C. or I.M. |
| T180 | 3339-3630 | Sentence | denotes | BALB/c mice Elicit SARS-CoV S-specific Abs (IgG, > 1:104) in mice, neutralizing (1:1.7 × 102 for S1; 1:90 for S1-foldon) live SARS-CoV (Urbani strain) N/A Protect vaccinated mice from challenge of SARS-CoV (Urbani strain, 105 TCID50) with undetectable viral load in lungs Li et al., 2013 |
| T181 | 3631-3662 | Sentence | denotes | S2 protein N/A Freund’s S.C. |
| T182 | 3664-3870 | Sentence | denotes | BALB/c mice Elicits SARS-CoV S2-specific Abs (IgG, 1:1.6 × 103) in mice with no neutralizing activity Induces SARS-CoV S2-specific cellular immune responses (IFN-γ and IL-4) in mice N/A Guo et al., 2005 |
| T183 | 3871-3946 | Sentence | denotes | Subunit vaccines based on SARS-CoV non-S structural proteins (i.e. N and M) |
| T184 | 3947-3978 | Sentence | denotes | rN protein N/A Freund’s I.P. |
| T185 | 3980-4181 | Sentence | denotes | BALB/c mice Elicits SARS-CoV N-specific Abs (IgG (1:1.8 × 103), IgG1, and IgG2a) in mice Induces cellular immune responses with up-regulated IFN-γ and IL-10 cytokines in mice N/A Zheng et al., 2009 |
| T186 | 4182-4230 | Sentence | denotes | rN protein N/A Montanide + CpG; Freund’s S.C. |
| T187 | 4232-4385 | Sentence | denotes | BALB/c mice Elicits SARS-CoV N-specific Abs (IgG) in mice Induces SARS-CoV N-specific cellular immune responses (IFN- γ) in mice N/A Liu et al., 2006 |
| T188 | 4386-4492 | Sentence | denotes | M1-31 and M132-161 peptides Bind to sera from SARS patients or immunized mice and rabbits Freund’s I.D. |
| T189 | 4494-4595 | Sentence | denotes | BALB/c mice; NZW rabbits Induce SARS-CoV M-specific Abs (IgG) in rabbits N/A N/A He et al., 2005b |