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LitCovid-PD-FMA-UBERON

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T23","span":{"begin":121,"end":144},"obj":"Body_part"},{"id":"T24","span":{"begin":173,"end":181},"obj":"Body_part"},{"id":"T25","span":{"begin":345,"end":348},"obj":"Body_part"},{"id":"T26","span":{"begin":428,"end":433},"obj":"Body_part"},{"id":"T27","span":{"begin":513,"end":520},"obj":"Body_part"},{"id":"T28","span":{"begin":619,"end":624},"obj":"Body_part"},{"id":"T29","span":{"begin":849,"end":853},"obj":"Body_part"}],"attributes":[{"id":"A23","pred":"fma_id","subj":"T23","obj":"http://purl.org/sig/ont/fma/fma45662"},{"id":"A24","pred":"fma_id","subj":"T24","obj":"http://purl.org/sig/ont/fma/fma84050"},{"id":"A25","pred":"fma_id","subj":"T25","obj":"http://purl.org/sig/ont/fma/fma55675"},{"id":"A26","pred":"fma_id","subj":"T26","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A27","pred":"fma_id","subj":"T27","obj":"http://purl.org/sig/ont/fma/fma296970"},{"id":"A28","pred":"fma_id","subj":"T28","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A29","pred":"fma_id","subj":"T29","obj":"http://purl.org/sig/ont/fma/fma7195"}],"text":"SARS-CoV was isolated and identified as the causative agent of SARS [9]. Unlike 229E and OC43, SARS-CoV infection causes lower respiratory tract infection, accompanied by a cytokine storm in patients with poor outcome. Life-threatening ARDS was developed in some critically ill patients. Apart from a respiratory infection, gastrointestinal and CNS infection was also found in some patients with SARS [10,11]. FRHK4 and Vero-E6 cells played an important role in the discovery of SARS-CoV [9]. The same as chicken embryos in which other CoVs including avian infectious bronchitis virus were isolated and cultured, these cells are highly susceptible to SARS-CoV infection because they are type I interferon-defective [12]. Consistent with this, infection of STAT1−/− mice with SARS-CoV resulted in a lethal outcome with a profibrotic phenotype in the lung [13]. These mice cannot clear the virus. All these highlight the importance of host antiviral response in the control of SARS-CoV infection at the cellular and organismal level."}

LitCovid-PD-UBERON

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T14","span":{"begin":121,"end":144},"obj":"Body_part"},{"id":"T15","span":{"begin":127,"end":144},"obj":"Body_part"},{"id":"T16","span":{"begin":345,"end":348},"obj":"Body_part"},{"id":"T17","span":{"begin":849,"end":853},"obj":"Body_part"}],"attributes":[{"id":"A14","pred":"uberon_id","subj":"T14","obj":"http://purl.obolibrary.org/obo/UBERON_0001558"},{"id":"A15","pred":"uberon_id","subj":"T15","obj":"http://purl.obolibrary.org/obo/UBERON_0000065"},{"id":"A16","pred":"uberon_id","subj":"T16","obj":"http://purl.obolibrary.org/obo/UBERON_0001017"},{"id":"A17","pred":"uberon_id","subj":"T17","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"}],"text":"SARS-CoV was isolated and identified as the causative agent of SARS [9]. Unlike 229E and OC43, SARS-CoV infection causes lower respiratory tract infection, accompanied by a cytokine storm in patients with poor outcome. Life-threatening ARDS was developed in some critically ill patients. Apart from a respiratory infection, gastrointestinal and CNS infection was also found in some patients with SARS [10,11]. FRHK4 and Vero-E6 cells played an important role in the discovery of SARS-CoV [9]. The same as chicken embryos in which other CoVs including avian infectious bronchitis virus were isolated and cultured, these cells are highly susceptible to SARS-CoV infection because they are type I interferon-defective [12]. Consistent with this, infection of STAT1−/− mice with SARS-CoV resulted in a lethal outcome with a profibrotic phenotype in the lung [13]. These mice cannot clear the virus. All these highlight the importance of host antiviral response in the control of SARS-CoV infection at the cellular and organismal level."}

LitCovid-PD-MONDO

LitCovid-PD-CLO

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T89","span":{"begin":121,"end":144},"obj":"http://purl.obolibrary.org/obo/UBERON_0001558"},{"id":"T90","span":{"begin":171,"end":172},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T91","span":{"begin":299,"end":300},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T92","span":{"begin":345,"end":348},"obj":"http://www.ebi.ac.uk/efo/EFO_0000302"},{"id":"T93","span":{"begin":345,"end":348},"obj":"http://www.ebi.ac.uk/efo/EFO_0000908"},{"id":"T94","span":{"begin":345,"end":348},"obj":"http://purl.obolibrary.org/obo/UBERON_0001017"},{"id":"T95","span":{"begin":410,"end":415},"obj":"http://purl.obolibrary.org/obo/CLO_0003388"},{"id":"T96","span":{"begin":420,"end":433},"obj":"http://purl.obolibrary.org/obo/CLO_0051719"},{"id":"T97","span":{"begin":505,"end":512},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9031"},{"id":"T98","span":{"begin":513,"end":520},"obj":"http://purl.obolibrary.org/obo/UBERON_0000922"},{"id":"T99","span":{"begin":579,"end":584},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T100","span":{"begin":603,"end":624},"obj":"http://purl.obolibrary.org/obo/CL_0000010"},{"id":"T101","span":{"begin":687,"end":704},"obj":"http://purl.obolibrary.org/obo/PR_000024990"},{"id":"T102","span":{"begin":796,"end":797},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T103","span":{"begin":818,"end":819},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T104","span":{"begin":849,"end":853},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T105","span":{"begin":849,"end":853},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T106","span":{"begin":888,"end":893},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"}],"text":"SARS-CoV was isolated and identified as the causative agent of SARS [9]. Unlike 229E and OC43, SARS-CoV infection causes lower respiratory tract infection, accompanied by a cytokine storm in patients with poor outcome. Life-threatening ARDS was developed in some critically ill patients. Apart from a respiratory infection, gastrointestinal and CNS infection was also found in some patients with SARS [10,11]. FRHK4 and Vero-E6 cells played an important role in the discovery of SARS-CoV [9]. The same as chicken embryos in which other CoVs including avian infectious bronchitis virus were isolated and cultured, these cells are highly susceptible to SARS-CoV infection because they are type I interferon-defective [12]. Consistent with this, infection of STAT1−/− mice with SARS-CoV resulted in a lethal outcome with a profibrotic phenotype in the lung [13]. These mice cannot clear the virus. All these highlight the importance of host antiviral response in the control of SARS-CoV infection at the cellular and organismal level."}

LitCovid-PD-CHEBI

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T19","span":{"begin":694,"end":704},"obj":"Chemical"},{"id":"T20","span":{"begin":938,"end":947},"obj":"Chemical"}],"attributes":[{"id":"A19","pred":"chebi_id","subj":"T19","obj":"http://purl.obolibrary.org/obo/CHEBI_52999"},{"id":"A20","pred":"chebi_id","subj":"T20","obj":"http://purl.obolibrary.org/obo/CHEBI_22587"}],"text":"SARS-CoV was isolated and identified as the causative agent of SARS [9]. Unlike 229E and OC43, SARS-CoV infection causes lower respiratory tract infection, accompanied by a cytokine storm in patients with poor outcome. Life-threatening ARDS was developed in some critically ill patients. Apart from a respiratory infection, gastrointestinal and CNS infection was also found in some patients with SARS [10,11]. FRHK4 and Vero-E6 cells played an important role in the discovery of SARS-CoV [9]. The same as chicken embryos in which other CoVs including avian infectious bronchitis virus were isolated and cultured, these cells are highly susceptible to SARS-CoV infection because they are type I interferon-defective [12]. Consistent with this, infection of STAT1−/− mice with SARS-CoV resulted in a lethal outcome with a profibrotic phenotype in the lung [13]. These mice cannot clear the virus. All these highlight the importance of host antiviral response in the control of SARS-CoV infection at the cellular and organismal level."}

LitCovid-PD-GO-BP

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T11","span":{"begin":938,"end":956},"obj":"http://purl.obolibrary.org/obo/GO_0051607"}],"text":"SARS-CoV was isolated and identified as the causative agent of SARS [9]. Unlike 229E and OC43, SARS-CoV infection causes lower respiratory tract infection, accompanied by a cytokine storm in patients with poor outcome. Life-threatening ARDS was developed in some critically ill patients. Apart from a respiratory infection, gastrointestinal and CNS infection was also found in some patients with SARS [10,11]. FRHK4 and Vero-E6 cells played an important role in the discovery of SARS-CoV [9]. The same as chicken embryos in which other CoVs including avian infectious bronchitis virus were isolated and cultured, these cells are highly susceptible to SARS-CoV infection because they are type I interferon-defective [12]. Consistent with this, infection of STAT1−/− mice with SARS-CoV resulted in a lethal outcome with a profibrotic phenotype in the lung [13]. These mice cannot clear the virus. All these highlight the importance of host antiviral response in the control of SARS-CoV infection at the cellular and organismal level."}

LitCovid-sentences

{"project":"LitCovid-sentences","denotations":[{"id":"T63","span":{"begin":0,"end":72},"obj":"Sentence"},{"id":"T64","span":{"begin":73,"end":218},"obj":"Sentence"},{"id":"T65","span":{"begin":219,"end":287},"obj":"Sentence"},{"id":"T66","span":{"begin":288,"end":409},"obj":"Sentence"},{"id":"T67","span":{"begin":410,"end":492},"obj":"Sentence"},{"id":"T68","span":{"begin":493,"end":720},"obj":"Sentence"},{"id":"T69","span":{"begin":721,"end":859},"obj":"Sentence"},{"id":"T70","span":{"begin":860,"end":894},"obj":"Sentence"},{"id":"T71","span":{"begin":895,"end":1031},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"SARS-CoV was isolated and identified as the causative agent of SARS [9]. Unlike 229E and OC43, SARS-CoV infection causes lower respiratory tract infection, accompanied by a cytokine storm in patients with poor outcome. Life-threatening ARDS was developed in some critically ill patients. Apart from a respiratory infection, gastrointestinal and CNS infection was also found in some patients with SARS [10,11]. FRHK4 and Vero-E6 cells played an important role in the discovery of SARS-CoV [9]. The same as chicken embryos in which other CoVs including avian infectious bronchitis virus were isolated and cultured, these cells are highly susceptible to SARS-CoV infection because they are type I interferon-defective [12]. Consistent with this, infection of STAT1−/− mice with SARS-CoV resulted in a lethal outcome with a profibrotic phenotype in the lung [13]. These mice cannot clear the virus. All these highlight the importance of host antiviral response in the control of SARS-CoV infection at the cellular and organismal level."}

LitCovid-PD-HP

{"project":"LitCovid-PD-HP","denotations":[{"id":"T11","span":{"begin":121,"end":154},"obj":"Phenotype"},{"id":"T12","span":{"begin":173,"end":187},"obj":"Phenotype"},{"id":"T13","span":{"begin":301,"end":322},"obj":"Phenotype"},{"id":"T14","span":{"begin":568,"end":578},"obj":"Phenotype"}],"attributes":[{"id":"A11","pred":"hp_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/HP_0002783"},{"id":"A12","pred":"hp_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/HP_0033041"},{"id":"A13","pred":"hp_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/HP_0011947"},{"id":"A14","pred":"hp_id","subj":"T14","obj":"http://purl.obolibrary.org/obo/HP_0012387"}],"text":"SARS-CoV was isolated and identified as the causative agent of SARS [9]. Unlike 229E and OC43, SARS-CoV infection causes lower respiratory tract infection, accompanied by a cytokine storm in patients with poor outcome. Life-threatening ARDS was developed in some critically ill patients. Apart from a respiratory infection, gastrointestinal and CNS infection was also found in some patients with SARS [10,11]. FRHK4 and Vero-E6 cells played an important role in the discovery of SARS-CoV [9]. The same as chicken embryos in which other CoVs including avian infectious bronchitis virus were isolated and cultured, these cells are highly susceptible to SARS-CoV infection because they are type I interferon-defective [12]. Consistent with this, infection of STAT1−/− mice with SARS-CoV resulted in a lethal outcome with a profibrotic phenotype in the lung [13]. These mice cannot clear the virus. All these highlight the importance of host antiviral response in the control of SARS-CoV infection at the cellular and organismal level."}

2_test

{"project":"2_test","denotations":[{"id":"32172672-12711465-27782202","span":{"begin":69,"end":70},"obj":"12711465"},{"id":"32172672-14517783-27782203","span":{"begin":402,"end":404},"obj":"14517783"},{"id":"32172672-16163626-27782204","span":{"begin":405,"end":407},"obj":"16163626"},{"id":"32172672-12711465-27782205","span":{"begin":489,"end":490},"obj":"12711465"},{"id":"32172672-4302013-27782206","span":{"begin":716,"end":718},"obj":"4302013"},{"id":"32172672-20702617-27782207","span":{"begin":855,"end":857},"obj":"20702617"}],"text":"SARS-CoV was isolated and identified as the causative agent of SARS [9]. Unlike 229E and OC43, SARS-CoV infection causes lower respiratory tract infection, accompanied by a cytokine storm in patients with poor outcome. Life-threatening ARDS was developed in some critically ill patients. Apart from a respiratory infection, gastrointestinal and CNS infection was also found in some patients with SARS [10,11]. FRHK4 and Vero-E6 cells played an important role in the discovery of SARS-CoV [9]. The same as chicken embryos in which other CoVs including avian infectious bronchitis virus were isolated and cultured, these cells are highly susceptible to SARS-CoV infection because they are type I interferon-defective [12]. Consistent with this, infection of STAT1−/− mice with SARS-CoV resulted in a lethal outcome with a profibrotic phenotype in the lung [13]. These mice cannot clear the virus. All these highlight the importance of host antiviral response in the control of SARS-CoV infection at the cellular and organismal level."}

LitCovid-PubTator

MyTest

{"project":"MyTest","denotations":[{"id":"32172672-12711465-27782202","span":{"begin":69,"end":70},"obj":"12711465"},{"id":"32172672-14517783-27782203","span":{"begin":402,"end":404},"obj":"14517783"},{"id":"32172672-16163626-27782204","span":{"begin":405,"end":407},"obj":"16163626"},{"id":"32172672-12711465-27782205","span":{"begin":489,"end":490},"obj":"12711465"},{"id":"32172672-4302013-27782206","span":{"begin":716,"end":718},"obj":"4302013"},{"id":"32172672-20702617-27782207","span":{"begin":855,"end":857},"obj":"20702617"}],"namespaces":[{"prefix":"_base","uri":"https://www.uniprot.org/uniprot/testbase"},{"prefix":"UniProtKB","uri":"https://www.uniprot.org/uniprot/"},{"prefix":"uniprot","uri":"https://www.uniprot.org/uniprotkb/"}],"text":"SARS-CoV was isolated and identified as the causative agent of SARS [9]. Unlike 229E and OC43, SARS-CoV infection causes lower respiratory tract infection, accompanied by a cytokine storm in patients with poor outcome. Life-threatening ARDS was developed in some critically ill patients. Apart from a respiratory infection, gastrointestinal and CNS infection was also found in some patients with SARS [10,11]. FRHK4 and Vero-E6 cells played an important role in the discovery of SARS-CoV [9]. The same as chicken embryos in which other CoVs including avian infectious bronchitis virus were isolated and cultured, these cells are highly susceptible to SARS-CoV infection because they are type I interferon-defective [12]. Consistent with this, infection of STAT1−/− mice with SARS-CoV resulted in a lethal outcome with a profibrotic phenotype in the lung [13]. These mice cannot clear the virus. All these highlight the importance of host antiviral response in the control of SARS-CoV infection at the cellular and organismal level."}

PMC:7103735 / 7632-8663 JSONTXT

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PMC:7103735 / 7632-8663 JSON TXT