PMC:7103724 / 8716-11428 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T21","span":{"begin":66,"end":82},"obj":"Body_part"},{"id":"T22","span":{"begin":78,"end":82},"obj":"Body_part"},{"id":"T23","span":{"begin":228,"end":233},"obj":"Body_part"},{"id":"T24","span":{"begin":238,"end":244},"obj":"Body_part"},{"id":"T25","span":{"begin":689,"end":694},"obj":"Body_part"},{"id":"T26","span":{"begin":717,"end":722},"obj":"Body_part"},{"id":"T27","span":{"begin":848,"end":853},"obj":"Body_part"},{"id":"T28","span":{"begin":1016,"end":1020},"obj":"Body_part"},{"id":"T29","span":{"begin":1320,"end":1323},"obj":"Body_part"},{"id":"T30","span":{"begin":1330,"end":1333},"obj":"Body_part"},{"id":"T31","span":{"begin":1340,"end":1343},"obj":"Body_part"},{"id":"T32","span":{"begin":2317,"end":2333},"obj":"Body_part"},{"id":"T33","span":{"begin":2329,"end":2333},"obj":"Body_part"},{"id":"T34","span":{"begin":2338,"end":2348},"obj":"Body_part"},{"id":"T35","span":{"begin":2353,"end":2363},"obj":"Body_part"},{"id":"T36","span":{"begin":2381,"end":2391},"obj":"Body_part"},{"id":"T37","span":{"begin":2398,"end":2409},"obj":"Body_part"},{"id":"T38","span":{"begin":2450,"end":2457},"obj":"Body_part"},{"id":"T39","span":{"begin":2536,"end":2539},"obj":"Body_part"},{"id":"T40","span":{"begin":2541,"end":2557},"obj":"Body_part"},{"id":"T41","span":{"begin":2541,"end":2555},"obj":"Body_part"},{"id":"T42","span":{"begin":2559,"end":2562},"obj":"Body_part"},{"id":"T43","span":{"begin":2564,"end":2580},"obj":"Body_part"},{"id":"T44","span":{"begin":2564,"end":2578},"obj":"Body_part"},{"id":"T45","span":{"begin":2586,"end":2602},"obj":"Body_part"},{"id":"T46","span":{"begin":2586,"end":2600},"obj":"Body_part"},{"id":"T47","span":{"begin":2654,"end":2659},"obj":"Body_part"},{"id":"T48","span":{"begin":2696,"end":2701},"obj":"Body_part"}],"attributes":[{"id":"A21","pred":"fma_id","subj":"T21","obj":"http://purl.org/sig/ont/fma/fma62852"},{"id":"A22","pred":"fma_id","subj":"T22","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A23","pred":"fma_id","subj":"T23","obj":"http://purl.org/sig/ont/fma/fma7197"},{"id":"A24","pred":"fma_id","subj":"T24","obj":"http://purl.org/sig/ont/fma/fma7203"},{"id":"A25","pred":"fma_id","subj":"T25","obj":"http://purl.org/sig/ont/fma/fma9576"},{"id":"A26","pred":"fma_id","subj":"T26","obj":"http://purl.org/sig/ont/fma/fma9576"},{"id":"A27","pred":"fma_id","subj":"T27","obj":"http://purl.org/sig/ont/fma/fma9576"},{"id":"A28","pred":"fma_id","subj":"T28","obj":"http://purl.org/sig/ont/fma/fma7195"},{"id":"A29","pred":"fma_id","subj":"T29","obj":"http://purl.org/sig/ont/fma/fma62873"},{"id":"A30","pred":"fma_id","subj":"T30","obj":"http://purl.org/sig/ont/fma/fma62874"},{"id":"A31","pred":"fma_id","subj":"T31","obj":"http://purl.org/sig/ont/fma/fma62872"},{"id":"A32","pred":"fma_id","subj":"T32","obj":"http://purl.org/sig/ont/fma/fma62852"},{"id":"A33","pred":"fma_id","subj":"T33","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A34","pred":"fma_id","subj":"T34","obj":"http://purl.org/sig/ont/fma/fma62860"},{"id":"A35","pred":"fma_id","subj":"T35","obj":"http://purl.org/sig/ont/fma/fma62863"},{"id":"A36","pred":"fma_id","subj":"T36","obj":"http://purl.org/sig/ont/fma/fma62293"},{"id":"A37","pred":"fma_id","subj":"T37","obj":"http://purl.org/sig/ont/fma/fma62845"},{"id":"A38","pred":"fma_id","subj":"T38","obj":"http://purl.org/sig/ont/fma/fma82749"},{"id":"A39","pred":"fma_id","subj":"T39","obj":"http://purl.org/sig/ont/fma/fma62873"},{"id":"A40","pred":"fma_id","subj":"T40","obj":"http://purl.org/sig/ont/fma/fma62873"},{"id":"A41","pred":"fma_id","subj":"T41","obj":"http://purl.org/sig/ont/fma/fma62871"},{"id":"A42","pred":"fma_id","subj":"T42","obj":"http://purl.org/sig/ont/fma/fma62872"},{"id":"A43","pred":"fma_id","subj":"T43","obj":"http://purl.org/sig/ont/fma/fma62872"},{"id":"A44","pred":"fma_id","subj":"T44","obj":"http://purl.org/sig/ont/fma/fma62871"},{"id":"A45","pred":"fma_id","subj":"T45","obj":"http://purl.org/sig/ont/fma/fma62874"},{"id":"A46","pred":"fma_id","subj":"T46","obj":"http://purl.org/sig/ont/fma/fma62871"},{"id":"A47","pred":"fma_id","subj":"T47","obj":"http://purl.org/sig/ont/fma/fma50801"},{"id":"A48","pred":"fma_id","subj":"T48","obj":"http://purl.org/sig/ont/fma/fma63083"}],"text":"As shown in Table 2, 8/9 (88.9%) children had normal or decreased white blood cell counts, consistent with the main characteristic of viral infection. Six children (66.7%) showed increased CK-MB. ALT, AST and the other index of liver and kidney were all normal. All inflammation indicators, including CRP, PCT, ESR and IL-6 were all within the normal range. Two children (22.2%) showed bronchitis and one (11.1%) showed bronchial pneumonia. One (11.1%) boy (the older of the twins) showed pulmonary consolidation and ground glass opacity on the first day (Figure 1(A)) admitted in the hospital, and disappeared after five days (Figure 1(B)). Five other (55.6%) children showed no abnormal chest radiograph.\nFigure 1: Chest CT images of a case 7 and case 8 (one pair of 11 month old twins) patient upon admission, who had no symptom. (A) Transverse chest CT images showed pulmonary consolidation and ground glass opacity (case 7 on 7 February). (B) Showed marked improvement after 5 days (case 7 on 13 February). (C) Lung CT of case 8 – the case 7’s younger brother on admission day (case 8 on 7 February).\nTable 2. The laboratory results of nine children patients.\nCase no. WBC (109/L) N (%) L (%) PLT (109/L) Hb (g/L) CRP (mg/L) ESR (mm/h) PCT (ug/L) IL-6 (pg/ml) ALT (U/L) AST (U/L) CK-MB (U/L) CD4 (%) CD8 (%) NK (%) IgM (g/L) IgA (g/L) IgG (g/L) C3 (g/L) C4 (g/L) Ferritin D-dimer Myoglobin (ug/l) BNP (pg/ml) SAA\n1 8.48 32.1 59.9 361 128 0.12 5 0.04 1.5 13 35 34 31.9 34.6 16.5 1.0 0.6 7 0.8 0.2 45.5 0.3 9 133 3\n2 7.55 20.4 73.6 193 120 0.35 2 0.08 1.5 14 33 28 28.3 27.1 27.3 1.2 0.8 7.3 0.8 0.3 33.6 0.3 11 24 4\n3 3.78 38.7 43.9 293 119 0.19 7 0.05 1.5 15 28 23 33.2 35.6 – 1.1 1.6 12.9 1.0 0.2 85.6 0.4 9 29 3\n4 4.14 23.6 69.3 65 129 0.18 6 0.04 1.5 14 28 30 46.6 20.2 8.5 1.1 0.8 6. 9 1.0 0.2 – 0.2 9 116 5\n5 3.69 33.8 53.3 169 106 0.12 5 0.03 1.5 15 23 22 45.7 33.4 14,8 0.9 0.6 8.1 0.1 1.0 48.1 0.1 9 87 3\n6 9.33 27.8 66.7 278 133 0.24 2 0.08 1.5 13 36 76 36.9 22.6 16.7 1.6 1.7 16.3 1.0 0.2 50.7 0.2 9 39 6\n7 11.17 17.2 77.4 305 117 0.19 2 0.04 1.5 22 39 43 – – – 1.3 0.3 7.1 0.7 0.1 62.6 0.3 9 31 3\n8 9.42 24.5 68.6 358 116 0.19 2 0.04 1.5 22 42 52 – – – 0.6 0.2 7.0 0.7 0.1 59.7 0.3 9 2 3\n9 5.45 41.2 53.0 235 140 0.26 3 0.02 1.5 9 24 27 33.1 29.3 16.5 1.3 1. 6 8.9 1.0 0.2 45.6 0.3 18 23 5\nNote: WBC, white blood cell; N, Neutrophil; L, Lymphocyte; PLT, plate; Hb, Hemoglobin; ESR, erythrocyte sedimentation; PCT, Procalcitonin; ALT, alanine aminotransferase; AST, aspartate aminotransferase; CK-MB, creatine kinase MB; IgM, Immunoglobulin M; IgG, Immunoglobulin G; Ig, Immunoglobulin A; C3, complement3; C4, complement4; BNP, N-terminal brain natriuretic peptide precursor; SAA, Serum amyloid A."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T16","span":{"begin":72,"end":77},"obj":"Body_part"},{"id":"T17","span":{"begin":228,"end":233},"obj":"Body_part"},{"id":"T18","span":{"begin":238,"end":244},"obj":"Body_part"},{"id":"T19","span":{"begin":689,"end":694},"obj":"Body_part"},{"id":"T20","span":{"begin":717,"end":722},"obj":"Body_part"},{"id":"T21","span":{"begin":848,"end":853},"obj":"Body_part"},{"id":"T22","span":{"begin":1016,"end":1020},"obj":"Body_part"},{"id":"T23","span":{"begin":2323,"end":2328},"obj":"Body_part"},{"id":"T24","span":{"begin":2654,"end":2659},"obj":"Body_part"},{"id":"T25","span":{"begin":2696,"end":2701},"obj":"Body_part"}],"attributes":[{"id":"A16","pred":"uberon_id","subj":"T16","obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"A17","pred":"uberon_id","subj":"T17","obj":"http://purl.obolibrary.org/obo/UBERON_0002107"},{"id":"A18","pred":"uberon_id","subj":"T18","obj":"http://purl.obolibrary.org/obo/UBERON_0002113"},{"id":"A19","pred":"uberon_id","subj":"T19","obj":"http://purl.obolibrary.org/obo/UBERON_0001443"},{"id":"A20","pred":"uberon_id","subj":"T20","obj":"http://purl.obolibrary.org/obo/UBERON_0001443"},{"id":"A21","pred":"uberon_id","subj":"T21","obj":"http://purl.obolibrary.org/obo/UBERON_0001443"},{"id":"A22","pred":"uberon_id","subj":"T22","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"A23","pred":"uberon_id","subj":"T23","obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"A24","pred":"uberon_id","subj":"T24","obj":"http://purl.obolibrary.org/obo/UBERON_0000955"},{"id":"A25","pred":"uberon_id","subj":"T25","obj":"http://purl.obolibrary.org/obo/UBERON_0001977"}],"text":"As shown in Table 2, 8/9 (88.9%) children had normal or decreased white blood cell counts, consistent with the main characteristic of viral infection. Six children (66.7%) showed increased CK-MB. ALT, AST and the other index of liver and kidney were all normal. All inflammation indicators, including CRP, PCT, ESR and IL-6 were all within the normal range. Two children (22.2%) showed bronchitis and one (11.1%) showed bronchial pneumonia. One (11.1%) boy (the older of the twins) showed pulmonary consolidation and ground glass opacity on the first day (Figure 1(A)) admitted in the hospital, and disappeared after five days (Figure 1(B)). Five other (55.6%) children showed no abnormal chest radiograph.\nFigure 1: Chest CT images of a case 7 and case 8 (one pair of 11 month old twins) patient upon admission, who had no symptom. (A) Transverse chest CT images showed pulmonary consolidation and ground glass opacity (case 7 on 7 February). (B) Showed marked improvement after 5 days (case 7 on 13 February). (C) Lung CT of case 8 – the case 7’s younger brother on admission day (case 8 on 7 February).\nTable 2. The laboratory results of nine children patients.\nCase no. WBC (109/L) N (%) L (%) PLT (109/L) Hb (g/L) CRP (mg/L) ESR (mm/h) PCT (ug/L) IL-6 (pg/ml) ALT (U/L) AST (U/L) CK-MB (U/L) CD4 (%) CD8 (%) NK (%) IgM (g/L) IgA (g/L) IgG (g/L) C3 (g/L) C4 (g/L) Ferritin D-dimer Myoglobin (ug/l) BNP (pg/ml) SAA\n1 8.48 32.1 59.9 361 128 0.12 5 0.04 1.5 13 35 34 31.9 34.6 16.5 1.0 0.6 7 0.8 0.2 45.5 0.3 9 133 3\n2 7.55 20.4 73.6 193 120 0.35 2 0.08 1.5 14 33 28 28.3 27.1 27.3 1.2 0.8 7.3 0.8 0.3 33.6 0.3 11 24 4\n3 3.78 38.7 43.9 293 119 0.19 7 0.05 1.5 15 28 23 33.2 35.6 – 1.1 1.6 12.9 1.0 0.2 85.6 0.4 9 29 3\n4 4.14 23.6 69.3 65 129 0.18 6 0.04 1.5 14 28 30 46.6 20.2 8.5 1.1 0.8 6. 9 1.0 0.2 – 0.2 9 116 5\n5 3.69 33.8 53.3 169 106 0.12 5 0.03 1.5 15 23 22 45.7 33.4 14,8 0.9 0.6 8.1 0.1 1.0 48.1 0.1 9 87 3\n6 9.33 27.8 66.7 278 133 0.24 2 0.08 1.5 13 36 76 36.9 22.6 16.7 1.6 1.7 16.3 1.0 0.2 50.7 0.2 9 39 6\n7 11.17 17.2 77.4 305 117 0.19 2 0.04 1.5 22 39 43 – – – 1.3 0.3 7.1 0.7 0.1 62.6 0.3 9 31 3\n8 9.42 24.5 68.6 358 116 0.19 2 0.04 1.5 22 42 52 – – – 0.6 0.2 7.0 0.7 0.1 59.7 0.3 9 2 3\n9 5.45 41.2 53.0 235 140 0.26 3 0.02 1.5 9 24 27 33.1 29.3 16.5 1.3 1. 6 8.9 1.0 0.2 45.6 0.3 18 23 5\nNote: WBC, white blood cell; N, Neutrophil; L, Lymphocyte; PLT, plate; Hb, Hemoglobin; ESR, erythrocyte sedimentation; PCT, Procalcitonin; ALT, alanine aminotransferase; AST, aspartate aminotransferase; CK-MB, creatine kinase MB; IgM, Immunoglobulin M; IgG, Immunoglobulin G; Ig, Immunoglobulin A; C3, complement3; C4, complement4; BNP, N-terminal brain natriuretic peptide precursor; SAA, Serum amyloid A."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T32","span":{"begin":134,"end":149},"obj":"Disease"},{"id":"T33","span":{"begin":140,"end":149},"obj":"Disease"},{"id":"T34","span":{"begin":189,"end":191},"obj":"Disease"},{"id":"T35","span":{"begin":266,"end":278},"obj":"Disease"},{"id":"T36","span":{"begin":306,"end":309},"obj":"Disease"},{"id":"T38","span":{"begin":386,"end":396},"obj":"Disease"},{"id":"T39","span":{"begin":420,"end":439},"obj":"Disease"},{"id":"T40","span":{"begin":430,"end":439},"obj":"Disease"},{"id":"T41","span":{"begin":1241,"end":1244},"obj":"Disease"},{"id":"T43","span":{"begin":1285,"end":1287},"obj":"Disease"},{"id":"T44","span":{"begin":2425,"end":2428},"obj":"Disease"},{"id":"T46","span":{"begin":2509,"end":2511},"obj":"Disease"},{"id":"T47","span":{"begin":2702,"end":2709},"obj":"Disease"}],"attributes":[{"id":"A32","pred":"mondo_id","subj":"T32","obj":"http://purl.obolibrary.org/obo/MONDO_0005108"},{"id":"A33","pred":"mondo_id","subj":"T33","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A34","pred":"mondo_id","subj":"T34","obj":"http://purl.obolibrary.org/obo/MONDO_0017941"},{"id":"A35","pred":"mondo_id","subj":"T35","obj":"http://purl.obolibrary.org/obo/MONDO_0021166"},{"id":"A36","pred":"mondo_id","subj":"T36","obj":"http://purl.obolibrary.org/obo/MONDO_0008296"},{"id":"A37","pred":"mondo_id","subj":"T36","obj":"http://purl.obolibrary.org/obo/MONDO_0015104"},{"id":"A38","pred":"mondo_id","subj":"T38","obj":"http://purl.obolibrary.org/obo/MONDO_0003781"},{"id":"A39","pred":"mondo_id","subj":"T39","obj":"http://purl.obolibrary.org/obo/MONDO_0005682"},{"id":"A40","pred":"mondo_id","subj":"T40","obj":"http://purl.obolibrary.org/obo/MONDO_0005249"},{"id":"A41","pred":"mondo_id","subj":"T41","obj":"http://purl.obolibrary.org/obo/MONDO_0008296"},{"id":"A42","pred":"mondo_id","subj":"T41","obj":"http://purl.obolibrary.org/obo/MONDO_0015104"},{"id":"A43","pred":"mondo_id","subj":"T43","obj":"http://purl.obolibrary.org/obo/MONDO_0017941"},{"id":"A44","pred":"mondo_id","subj":"T44","obj":"http://purl.obolibrary.org/obo/MONDO_0008296"},{"id":"A45","pred":"mondo_id","subj":"T44","obj":"http://purl.obolibrary.org/obo/MONDO_0015104"},{"id":"A46","pred":"mondo_id","subj":"T46","obj":"http://purl.obolibrary.org/obo/MONDO_0017941"},{"id":"A47","pred":"mondo_id","subj":"T47","obj":"http://purl.obolibrary.org/obo/MONDO_0019065"}],"text":"As shown in Table 2, 8/9 (88.9%) children had normal or decreased white blood cell counts, consistent with the main characteristic of viral infection. Six children (66.7%) showed increased CK-MB. ALT, AST and the other index of liver and kidney were all normal. All inflammation indicators, including CRP, PCT, ESR and IL-6 were all within the normal range. Two children (22.2%) showed bronchitis and one (11.1%) showed bronchial pneumonia. One (11.1%) boy (the older of the twins) showed pulmonary consolidation and ground glass opacity on the first day (Figure 1(A)) admitted in the hospital, and disappeared after five days (Figure 1(B)). Five other (55.6%) children showed no abnormal chest radiograph.\nFigure 1: Chest CT images of a case 7 and case 8 (one pair of 11 month old twins) patient upon admission, who had no symptom. (A) Transverse chest CT images showed pulmonary consolidation and ground glass opacity (case 7 on 7 February). (B) Showed marked improvement after 5 days (case 7 on 13 February). (C) Lung CT of case 8 – the case 7’s younger brother on admission day (case 8 on 7 February).\nTable 2. The laboratory results of nine children patients.\nCase no. WBC (109/L) N (%) L (%) PLT (109/L) Hb (g/L) CRP (mg/L) ESR (mm/h) PCT (ug/L) IL-6 (pg/ml) ALT (U/L) AST (U/L) CK-MB (U/L) CD4 (%) CD8 (%) NK (%) IgM (g/L) IgA (g/L) IgG (g/L) C3 (g/L) C4 (g/L) Ferritin D-dimer Myoglobin (ug/l) BNP (pg/ml) SAA\n1 8.48 32.1 59.9 361 128 0.12 5 0.04 1.5 13 35 34 31.9 34.6 16.5 1.0 0.6 7 0.8 0.2 45.5 0.3 9 133 3\n2 7.55 20.4 73.6 193 120 0.35 2 0.08 1.5 14 33 28 28.3 27.1 27.3 1.2 0.8 7.3 0.8 0.3 33.6 0.3 11 24 4\n3 3.78 38.7 43.9 293 119 0.19 7 0.05 1.5 15 28 23 33.2 35.6 – 1.1 1.6 12.9 1.0 0.2 85.6 0.4 9 29 3\n4 4.14 23.6 69.3 65 129 0.18 6 0.04 1.5 14 28 30 46.6 20.2 8.5 1.1 0.8 6. 9 1.0 0.2 – 0.2 9 116 5\n5 3.69 33.8 53.3 169 106 0.12 5 0.03 1.5 15 23 22 45.7 33.4 14,8 0.9 0.6 8.1 0.1 1.0 48.1 0.1 9 87 3\n6 9.33 27.8 66.7 278 133 0.24 2 0.08 1.5 13 36 76 36.9 22.6 16.7 1.6 1.7 16.3 1.0 0.2 50.7 0.2 9 39 6\n7 11.17 17.2 77.4 305 117 0.19 2 0.04 1.5 22 39 43 – – – 1.3 0.3 7.1 0.7 0.1 62.6 0.3 9 31 3\n8 9.42 24.5 68.6 358 116 0.19 2 0.04 1.5 22 42 52 – – – 0.6 0.2 7.0 0.7 0.1 59.7 0.3 9 2 3\n9 5.45 41.2 53.0 235 140 0.26 3 0.02 1.5 9 24 27 33.1 29.3 16.5 1.3 1. 6 8.9 1.0 0.2 45.6 0.3 18 23 5\nNote: WBC, white blood cell; N, Neutrophil; L, Lymphocyte; PLT, plate; Hb, Hemoglobin; ESR, erythrocyte sedimentation; PCT, Procalcitonin; ALT, alanine aminotransferase; AST, aspartate aminotransferase; CK-MB, creatine kinase MB; IgM, Immunoglobulin M; IgG, Immunoglobulin G; Ig, Immunoglobulin A; C3, complement3; C4, complement4; BNP, N-terminal brain natriuretic peptide precursor; SAA, Serum amyloid A."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T60","span":{"begin":72,"end":77},"obj":"http://www.ebi.ac.uk/efo/EFO_0000296"},{"id":"T61","span":{"begin":78,"end":82},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T62","span":{"begin":192,"end":194},"obj":"http://purl.obolibrary.org/obo/PR_000010213"},{"id":"T63","span":{"begin":228,"end":233},"obj":"http://purl.obolibrary.org/obo/UBERON_0002107"},{"id":"T64","span":{"begin":228,"end":233},"obj":"http://www.ebi.ac.uk/efo/EFO_0000887"},{"id":"T65","span":{"begin":238,"end":244},"obj":"http://purl.obolibrary.org/obo/UBERON_0002113"},{"id":"T66","span":{"begin":238,"end":244},"obj":"http://www.ebi.ac.uk/efo/EFO_0000927"},{"id":"T67","span":{"begin":238,"end":244},"obj":"http://www.ebi.ac.uk/efo/EFO_0000929"},{"id":"T68","span":{"begin":565,"end":566},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T69","span":{"begin":637,"end":638},"obj":"http://purl.obolibrary.org/obo/CLO_0001021"},{"id":"T70","span":{"begin":689,"end":694},"obj":"http://www.ebi.ac.uk/efo/EFO_0000965"},{"id":"T71","span":{"begin":717,"end":722},"obj":"http://www.ebi.ac.uk/efo/EFO_0000965"},{"id":"T72","span":{"begin":736,"end":737},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T73","span":{"begin":769,"end":771},"obj":"http://purl.obolibrary.org/obo/CLO_0053733"},{"id":"T74","span":{"begin":834,"end":835},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T75","span":{"begin":848,"end":853},"obj":"http://www.ebi.ac.uk/efo/EFO_0000965"},{"id":"T76","span":{"begin":945,"end":946},"obj":"http://purl.obolibrary.org/obo/CLO_0001021"},{"id":"T77","span":{"begin":1016,"end":1020},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T78","span":{"begin":1016,"end":1020},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T79","span":{"begin":1210,"end":1212},"obj":"http://purl.obolibrary.org/obo/CLO_0003622"},{"id":"T80","span":{"begin":1258,"end":1260},"obj":"http://purl.obolibrary.org/obo/CLO_0008426"},{"id":"T81","span":{"begin":1288,"end":1290},"obj":"http://purl.obolibrary.org/obo/PR_000010213"},{"id":"T82","span":{"begin":1297,"end":1300},"obj":"http://purl.obolibrary.org/obo/PR_000001004"},{"id":"T83","span":{"begin":1305,"end":1308},"obj":"http://purl.obolibrary.org/obo/CLO_0053438"},{"id":"T84","span":{"begin":1359,"end":1361},"obj":"http://purl.obolibrary.org/obo/CLO_0037284"},{"id":"T85","span":{"begin":1385,"end":1394},"obj":"http://purl.obolibrary.org/obo/PR_000010213"},{"id":"T86","span":{"begin":1407,"end":1409},"obj":"http://purl.obolibrary.org/obo/CLO_0008426"},{"id":"T87","span":{"begin":1462,"end":1464},"obj":"http://purl.obolibrary.org/obo/CLO_0001000"},{"id":"T88","span":{"begin":1465,"end":1467},"obj":"http://purl.obolibrary.org/obo/CLO_0001302"},{"id":"T89","span":{"begin":1612,"end":1614},"obj":"http://purl.obolibrary.org/obo/CLO_0053733"},{"id":"T90","span":{"begin":1637,"end":1640},"obj":"http://purl.obolibrary.org/obo/CLO_0001230"},{"id":"T91","span":{"begin":1637,"end":1640},"obj":"http://purl.obolibrary.org/obo/CLO_0037237"},{"id":"T92","span":{"begin":1637,"end":1640},"obj":"http://purl.obolibrary.org/obo/CLO_0050903"},{"id":"T93","span":{"begin":1637,"end":1640},"obj":"http://purl.obolibrary.org/obo/CLO_0054249"},{"id":"T94","span":{"begin":1637,"end":1640},"obj":"http://purl.obolibrary.org/obo/CLO_0054250"},{"id":"T95","span":{"begin":1637,"end":1640},"obj":"http://purl.obolibrary.org/obo/CLO_0054251"},{"id":"T96","span":{"begin":1637,"end":1640},"obj":"http://purl.obolibrary.org/obo/CLO_0054252"},{"id":"T97","span":{"begin":1714,"end":1718},"obj":"http://purl.obolibrary.org/obo/CLO_0001230"},{"id":"T98","span":{"begin":1714,"end":1718},"obj":"http://purl.obolibrary.org/obo/CLO_0037237"},{"id":"T99","span":{"begin":1714,"end":1718},"obj":"http://purl.obolibrary.org/obo/CLO_0050903"},{"id":"T100","span":{"begin":1714,"end":1718},"obj":"http://purl.obolibrary.org/obo/CLO_0054249"},{"id":"T101","span":{"begin":1714,"end":1718},"obj":"http://purl.obolibrary.org/obo/CLO_0054250"},{"id":"T102","span":{"begin":1714,"end":1718},"obj":"http://purl.obolibrary.org/obo/CLO_0054251"},{"id":"T103","span":{"begin":1714,"end":1718},"obj":"http://purl.obolibrary.org/obo/CLO_0054252"},{"id":"T104","span":{"begin":1811,"end":1814},"obj":"http://purl.obolibrary.org/obo/CLO_0001046"},{"id":"T105","span":{"begin":1864,"end":1866},"obj":"http://purl.obolibrary.org/obo/CLO_0050507"},{"id":"T106","span":{"begin":1962,"end":1964},"obj":"http://purl.obolibrary.org/obo/CLO_0001313"},{"id":"T107","span":{"begin":2062,"end":2064},"obj":"http://purl.obolibrary.org/obo/CLO_0050507"},{"id":"T108","span":{"begin":2134,"end":2137},"obj":"http://purl.obolibrary.org/obo/CLO_0001046"},{"id":"T109","span":{"begin":2154,"end":2156},"obj":"http://purl.obolibrary.org/obo/CLO_0050507"},{"id":"T110","span":{"begin":2160,"end":2162},"obj":"http://purl.obolibrary.org/obo/CLO_0001407"},{"id":"T111","span":{"begin":2250,"end":2252},"obj":"http://purl.obolibrary.org/obo/CLO_0050509"},{"id":"T112","span":{"begin":2298,"end":2300},"obj":"http://purl.obolibrary.org/obo/CLO_0050510"},{"id":"T113","span":{"begin":2323,"end":2328},"obj":"http://www.ebi.ac.uk/efo/EFO_0000296"},{"id":"T114","span":{"begin":2329,"end":2333},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T115","span":{"begin":2377,"end":2379},"obj":"http://purl.obolibrary.org/obo/CLO_0003622"},{"id":"T116","span":{"begin":2398,"end":2409},"obj":"http://purl.obolibrary.org/obo/CL_0000232"},{"id":"T117","span":{"begin":2512,"end":2514},"obj":"http://purl.obolibrary.org/obo/PR_000010213"},{"id":"T118","span":{"begin":2532,"end":2534},"obj":"http://purl.obolibrary.org/obo/PR_000010213"},{"id":"T119","span":{"begin":2601,"end":2602},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T120","span":{"begin":2621,"end":2623},"obj":"http://purl.obolibrary.org/obo/CLO_0037284"},{"id":"T121","span":{"begin":2654,"end":2659},"obj":"http://purl.obolibrary.org/obo/UBERON_0000955"},{"id":"T122","span":{"begin":2654,"end":2659},"obj":"http://www.ebi.ac.uk/efo/EFO_0000302"},{"id":"T123","span":{"begin":2672,"end":2679},"obj":"http://purl.obolibrary.org/obo/PR_000018263"},{"id":"T124","span":{"begin":2710,"end":2711},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"As shown in Table 2, 8/9 (88.9%) children had normal or decreased white blood cell counts, consistent with the main characteristic of viral infection. Six children (66.7%) showed increased CK-MB. ALT, AST and the other index of liver and kidney were all normal. All inflammation indicators, including CRP, PCT, ESR and IL-6 were all within the normal range. Two children (22.2%) showed bronchitis and one (11.1%) showed bronchial pneumonia. One (11.1%) boy (the older of the twins) showed pulmonary consolidation and ground glass opacity on the first day (Figure 1(A)) admitted in the hospital, and disappeared after five days (Figure 1(B)). Five other (55.6%) children showed no abnormal chest radiograph.\nFigure 1: Chest CT images of a case 7 and case 8 (one pair of 11 month old twins) patient upon admission, who had no symptom. (A) Transverse chest CT images showed pulmonary consolidation and ground glass opacity (case 7 on 7 February). (B) Showed marked improvement after 5 days (case 7 on 13 February). (C) Lung CT of case 8 – the case 7’s younger brother on admission day (case 8 on 7 February).\nTable 2. The laboratory results of nine children patients.\nCase no. WBC (109/L) N (%) L (%) PLT (109/L) Hb (g/L) CRP (mg/L) ESR (mm/h) PCT (ug/L) IL-6 (pg/ml) ALT (U/L) AST (U/L) CK-MB (U/L) CD4 (%) CD8 (%) NK (%) IgM (g/L) IgA (g/L) IgG (g/L) C3 (g/L) C4 (g/L) Ferritin D-dimer Myoglobin (ug/l) BNP (pg/ml) SAA\n1 8.48 32.1 59.9 361 128 0.12 5 0.04 1.5 13 35 34 31.9 34.6 16.5 1.0 0.6 7 0.8 0.2 45.5 0.3 9 133 3\n2 7.55 20.4 73.6 193 120 0.35 2 0.08 1.5 14 33 28 28.3 27.1 27.3 1.2 0.8 7.3 0.8 0.3 33.6 0.3 11 24 4\n3 3.78 38.7 43.9 293 119 0.19 7 0.05 1.5 15 28 23 33.2 35.6 – 1.1 1.6 12.9 1.0 0.2 85.6 0.4 9 29 3\n4 4.14 23.6 69.3 65 129 0.18 6 0.04 1.5 14 28 30 46.6 20.2 8.5 1.1 0.8 6. 9 1.0 0.2 – 0.2 9 116 5\n5 3.69 33.8 53.3 169 106 0.12 5 0.03 1.5 15 23 22 45.7 33.4 14,8 0.9 0.6 8.1 0.1 1.0 48.1 0.1 9 87 3\n6 9.33 27.8 66.7 278 133 0.24 2 0.08 1.5 13 36 76 36.9 22.6 16.7 1.6 1.7 16.3 1.0 0.2 50.7 0.2 9 39 6\n7 11.17 17.2 77.4 305 117 0.19 2 0.04 1.5 22 39 43 – – – 1.3 0.3 7.1 0.7 0.1 62.6 0.3 9 31 3\n8 9.42 24.5 68.6 358 116 0.19 2 0.04 1.5 22 42 52 – – – 0.6 0.2 7.0 0.7 0.1 59.7 0.3 9 2 3\n9 5.45 41.2 53.0 235 140 0.26 3 0.02 1.5 9 24 27 33.1 29.3 16.5 1.3 1. 6 8.9 1.0 0.2 45.6 0.3 18 23 5\nNote: WBC, white blood cell; N, Neutrophil; L, Lymphocyte; PLT, plate; Hb, Hemoglobin; ESR, erythrocyte sedimentation; PCT, Procalcitonin; ALT, alanine aminotransferase; AST, aspartate aminotransferase; CK-MB, creatine kinase MB; IgM, Immunoglobulin M; IgG, Immunoglobulin G; Ig, Immunoglobulin A; C3, complement3; C4, complement4; BNP, N-terminal brain natriuretic peptide precursor; SAA, Serum amyloid A."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T23","span":{"begin":201,"end":204},"obj":"Chemical"},{"id":"T24","span":{"begin":319,"end":321},"obj":"Chemical"},{"id":"T26","span":{"begin":1252,"end":1254},"obj":"Chemical"},{"id":"T28","span":{"begin":1275,"end":1278},"obj":"Chemical"},{"id":"T29","span":{"begin":1368,"end":1376},"obj":"Chemical"},{"id":"T30","span":{"begin":1385,"end":1394},"obj":"Chemical"},{"id":"T31","span":{"begin":1402,"end":1405},"obj":"Chemical"},{"id":"T32","span":{"begin":2381,"end":2391},"obj":"Chemical"},{"id":"T33","span":{"begin":2450,"end":2457},"obj":"Chemical"},{"id":"T34","span":{"begin":2476,"end":2479},"obj":"Chemical"},{"id":"T35","span":{"begin":2481,"end":2490},"obj":"Chemical"},{"id":"T38","span":{"begin":2516,"end":2524},"obj":"Chemical"},{"id":"T40","span":{"begin":2638,"end":2641},"obj":"Chemical"},{"id":"T41","span":{"begin":2654,"end":2679},"obj":"Chemical"},{"id":"T42","span":{"begin":2672,"end":2679},"obj":"Chemical"}],"attributes":[{"id":"A23","pred":"chebi_id","subj":"T23","obj":"http://purl.obolibrary.org/obo/CHEBI_76649"},{"id":"A24","pred":"chebi_id","subj":"T24","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A25","pred":"chebi_id","subj":"T24","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"},{"id":"A26","pred":"chebi_id","subj":"T26","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A27","pred":"chebi_id","subj":"T26","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"},{"id":"A28","pred":"chebi_id","subj":"T28","obj":"http://purl.obolibrary.org/obo/CHEBI_76649"},{"id":"A29","pred":"chebi_id","subj":"T29","obj":"http://purl.obolibrary.org/obo/CHEBI_82594"},{"id":"A30","pred":"chebi_id","subj":"T30","obj":"http://purl.obolibrary.org/obo/CHEBI_7044"},{"id":"A31","pred":"chebi_id","subj":"T31","obj":"http://purl.obolibrary.org/obo/CHEBI_80234"},{"id":"A32","pred":"chebi_id","subj":"T32","obj":"http://purl.obolibrary.org/obo/CHEBI_5656"},{"id":"A33","pred":"chebi_id","subj":"T33","obj":"http://purl.obolibrary.org/obo/CHEBI_16449"},{"id":"A34","pred":"chebi_id","subj":"T34","obj":"http://purl.obolibrary.org/obo/CHEBI_76649"},{"id":"A35","pred":"chebi_id","subj":"T35","obj":"http://purl.obolibrary.org/obo/CHEBI_132943"},{"id":"A36","pred":"chebi_id","subj":"T35","obj":"http://purl.obolibrary.org/obo/CHEBI_29995"},{"id":"A37","pred":"chebi_id","subj":"T35","obj":"http://purl.obolibrary.org/obo/CHEBI_72314"},{"id":"A38","pred":"chebi_id","subj":"T38","obj":"http://purl.obolibrary.org/obo/CHEBI_16919"},{"id":"A39","pred":"chebi_id","subj":"T38","obj":"http://purl.obolibrary.org/obo/CHEBI_57947"},{"id":"A40","pred":"chebi_id","subj":"T40","obj":"http://purl.obolibrary.org/obo/CHEBI_80234"},{"id":"A41","pred":"chebi_id","subj":"T41","obj":"http://purl.obolibrary.org/obo/CHEBI_80234"},{"id":"A42","pred":"chebi_id","subj":"T42","obj":"http://purl.obolibrary.org/obo/CHEBI_16670"}],"text":"As shown in Table 2, 8/9 (88.9%) children had normal or decreased white blood cell counts, consistent with the main characteristic of viral infection. Six children (66.7%) showed increased CK-MB. ALT, AST and the other index of liver and kidney were all normal. All inflammation indicators, including CRP, PCT, ESR and IL-6 were all within the normal range. Two children (22.2%) showed bronchitis and one (11.1%) showed bronchial pneumonia. One (11.1%) boy (the older of the twins) showed pulmonary consolidation and ground glass opacity on the first day (Figure 1(A)) admitted in the hospital, and disappeared after five days (Figure 1(B)). Five other (55.6%) children showed no abnormal chest radiograph.\nFigure 1: Chest CT images of a case 7 and case 8 (one pair of 11 month old twins) patient upon admission, who had no symptom. (A) Transverse chest CT images showed pulmonary consolidation and ground glass opacity (case 7 on 7 February). (B) Showed marked improvement after 5 days (case 7 on 13 February). (C) Lung CT of case 8 – the case 7’s younger brother on admission day (case 8 on 7 February).\nTable 2. The laboratory results of nine children patients.\nCase no. WBC (109/L) N (%) L (%) PLT (109/L) Hb (g/L) CRP (mg/L) ESR (mm/h) PCT (ug/L) IL-6 (pg/ml) ALT (U/L) AST (U/L) CK-MB (U/L) CD4 (%) CD8 (%) NK (%) IgM (g/L) IgA (g/L) IgG (g/L) C3 (g/L) C4 (g/L) Ferritin D-dimer Myoglobin (ug/l) BNP (pg/ml) SAA\n1 8.48 32.1 59.9 361 128 0.12 5 0.04 1.5 13 35 34 31.9 34.6 16.5 1.0 0.6 7 0.8 0.2 45.5 0.3 9 133 3\n2 7.55 20.4 73.6 193 120 0.35 2 0.08 1.5 14 33 28 28.3 27.1 27.3 1.2 0.8 7.3 0.8 0.3 33.6 0.3 11 24 4\n3 3.78 38.7 43.9 293 119 0.19 7 0.05 1.5 15 28 23 33.2 35.6 – 1.1 1.6 12.9 1.0 0.2 85.6 0.4 9 29 3\n4 4.14 23.6 69.3 65 129 0.18 6 0.04 1.5 14 28 30 46.6 20.2 8.5 1.1 0.8 6. 9 1.0 0.2 – 0.2 9 116 5\n5 3.69 33.8 53.3 169 106 0.12 5 0.03 1.5 15 23 22 45.7 33.4 14,8 0.9 0.6 8.1 0.1 1.0 48.1 0.1 9 87 3\n6 9.33 27.8 66.7 278 133 0.24 2 0.08 1.5 13 36 76 36.9 22.6 16.7 1.6 1.7 16.3 1.0 0.2 50.7 0.2 9 39 6\n7 11.17 17.2 77.4 305 117 0.19 2 0.04 1.5 22 39 43 – – – 1.3 0.3 7.1 0.7 0.1 62.6 0.3 9 31 3\n8 9.42 24.5 68.6 358 116 0.19 2 0.04 1.5 22 42 52 – – – 0.6 0.2 7.0 0.7 0.1 59.7 0.3 9 2 3\n9 5.45 41.2 53.0 235 140 0.26 3 0.02 1.5 9 24 27 33.1 29.3 16.5 1.3 1. 6 8.9 1.0 0.2 45.6 0.3 18 23 5\nNote: WBC, white blood cell; N, Neutrophil; L, Lymphocyte; PLT, plate; Hb, Hemoglobin; ESR, erythrocyte sedimentation; PCT, Procalcitonin; ALT, alanine aminotransferase; AST, aspartate aminotransferase; CK-MB, creatine kinase MB; IgM, Immunoglobulin M; IgG, Immunoglobulin G; Ig, Immunoglobulin A; C3, complement3; C4, complement4; BNP, N-terminal brain natriuretic peptide precursor; SAA, Serum amyloid A."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T2","span":{"begin":134,"end":149},"obj":"http://purl.obolibrary.org/obo/GO_0016032"},{"id":"T3","span":{"begin":189,"end":194},"obj":"http://purl.obolibrary.org/obo/GO_0004111"},{"id":"T4","span":{"begin":266,"end":278},"obj":"http://purl.obolibrary.org/obo/GO_0006954"},{"id":"T5","span":{"begin":1285,"end":1290},"obj":"http://purl.obolibrary.org/obo/GO_0004111"},{"id":"T6","span":{"begin":2509,"end":2514},"obj":"http://purl.obolibrary.org/obo/GO_0004111"}],"text":"As shown in Table 2, 8/9 (88.9%) children had normal or decreased white blood cell counts, consistent with the main characteristic of viral infection. Six children (66.7%) showed increased CK-MB. ALT, AST and the other index of liver and kidney were all normal. All inflammation indicators, including CRP, PCT, ESR and IL-6 were all within the normal range. Two children (22.2%) showed bronchitis and one (11.1%) showed bronchial pneumonia. One (11.1%) boy (the older of the twins) showed pulmonary consolidation and ground glass opacity on the first day (Figure 1(A)) admitted in the hospital, and disappeared after five days (Figure 1(B)). Five other (55.6%) children showed no abnormal chest radiograph.\nFigure 1: Chest CT images of a case 7 and case 8 (one pair of 11 month old twins) patient upon admission, who had no symptom. (A) Transverse chest CT images showed pulmonary consolidation and ground glass opacity (case 7 on 7 February). (B) Showed marked improvement after 5 days (case 7 on 13 February). (C) Lung CT of case 8 – the case 7’s younger brother on admission day (case 8 on 7 February).\nTable 2. The laboratory results of nine children patients.\nCase no. WBC (109/L) N (%) L (%) PLT (109/L) Hb (g/L) CRP (mg/L) ESR (mm/h) PCT (ug/L) IL-6 (pg/ml) ALT (U/L) AST (U/L) CK-MB (U/L) CD4 (%) CD8 (%) NK (%) IgM (g/L) IgA (g/L) IgG (g/L) C3 (g/L) C4 (g/L) Ferritin D-dimer Myoglobin (ug/l) BNP (pg/ml) SAA\n1 8.48 32.1 59.9 361 128 0.12 5 0.04 1.5 13 35 34 31.9 34.6 16.5 1.0 0.6 7 0.8 0.2 45.5 0.3 9 133 3\n2 7.55 20.4 73.6 193 120 0.35 2 0.08 1.5 14 33 28 28.3 27.1 27.3 1.2 0.8 7.3 0.8 0.3 33.6 0.3 11 24 4\n3 3.78 38.7 43.9 293 119 0.19 7 0.05 1.5 15 28 23 33.2 35.6 – 1.1 1.6 12.9 1.0 0.2 85.6 0.4 9 29 3\n4 4.14 23.6 69.3 65 129 0.18 6 0.04 1.5 14 28 30 46.6 20.2 8.5 1.1 0.8 6. 9 1.0 0.2 – 0.2 9 116 5\n5 3.69 33.8 53.3 169 106 0.12 5 0.03 1.5 15 23 22 45.7 33.4 14,8 0.9 0.6 8.1 0.1 1.0 48.1 0.1 9 87 3\n6 9.33 27.8 66.7 278 133 0.24 2 0.08 1.5 13 36 76 36.9 22.6 16.7 1.6 1.7 16.3 1.0 0.2 50.7 0.2 9 39 6\n7 11.17 17.2 77.4 305 117 0.19 2 0.04 1.5 22 39 43 – – – 1.3 0.3 7.1 0.7 0.1 62.6 0.3 9 31 3\n8 9.42 24.5 68.6 358 116 0.19 2 0.04 1.5 22 42 52 – – – 0.6 0.2 7.0 0.7 0.1 59.7 0.3 9 2 3\n9 5.45 41.2 53.0 235 140 0.26 3 0.02 1.5 9 24 27 33.1 29.3 16.5 1.3 1. 6 8.9 1.0 0.2 45.6 0.3 18 23 5\nNote: WBC, white blood cell; N, Neutrophil; L, Lymphocyte; PLT, plate; Hb, Hemoglobin; ESR, erythrocyte sedimentation; PCT, Procalcitonin; ALT, alanine aminotransferase; AST, aspartate aminotransferase; CK-MB, creatine kinase MB; IgM, Immunoglobulin M; IgG, Immunoglobulin G; Ig, Immunoglobulin A; C3, complement3; C4, complement4; BNP, N-terminal brain natriuretic peptide precursor; SAA, Serum amyloid A."}

{"project":"LitCovid-sentences","denotations":[{"id":"T72","span":{"begin":0,"end":150},"obj":"Sentence"},{"id":"T73","span":{"begin":151,"end":195},"obj":"Sentence"},{"id":"T74","span":{"begin":196,"end":261},"obj":"Sentence"},{"id":"T75","span":{"begin":262,"end":357},"obj":"Sentence"},{"id":"T76","span":{"begin":358,"end":440},"obj":"Sentence"},{"id":"T77","span":{"begin":441,"end":641},"obj":"Sentence"},{"id":"T78","span":{"begin":642,"end":706},"obj":"Sentence"},{"id":"T79","span":{"begin":707,"end":716},"obj":"Sentence"},{"id":"T80","span":{"begin":717,"end":1105},"obj":"Sentence"},{"id":"T81","span":{"begin":1106,"end":1114},"obj":"Sentence"},{"id":"T82","span":{"begin":1115,"end":1164},"obj":"Sentence"},{"id":"T83","span":{"begin":1165,"end":1173},"obj":"Sentence"},{"id":"T84","span":{"begin":1174,"end":1417},"obj":"Sentence"},{"id":"T85","span":{"begin":1418,"end":1517},"obj":"Sentence"},{"id":"T86","span":{"begin":1518,"end":1619},"obj":"Sentence"},{"id":"T87","span":{"begin":1620,"end":1718},"obj":"Sentence"},{"id":"T88","span":{"begin":1719,"end":1792},"obj":"Sentence"},{"id":"T89","span":{"begin":1793,"end":1816},"obj":"Sentence"},{"id":"T90","span":{"begin":1817,"end":1917},"obj":"Sentence"},{"id":"T91","span":{"begin":1918,"end":2019},"obj":"Sentence"},{"id":"T92","span":{"begin":2020,"end":2112},"obj":"Sentence"},{"id":"T93","span":{"begin":2113,"end":2203},"obj":"Sentence"},{"id":"T94","span":{"begin":2204,"end":2274},"obj":"Sentence"},{"id":"T95","span":{"begin":2275,"end":2305},"obj":"Sentence"},{"id":"T96","span":{"begin":2306,"end":2712},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"As shown in Table 2, 8/9 (88.9%) children had normal or decreased white blood cell counts, consistent with the main characteristic of viral infection. Six children (66.7%) showed increased CK-MB. ALT, AST and the other index of liver and kidney were all normal. All inflammation indicators, including CRP, PCT, ESR and IL-6 were all within the normal range. Two children (22.2%) showed bronchitis and one (11.1%) showed bronchial pneumonia. One (11.1%) boy (the older of the twins) showed pulmonary consolidation and ground glass opacity on the first day (Figure 1(A)) admitted in the hospital, and disappeared after five days (Figure 1(B)). Five other (55.6%) children showed no abnormal chest radiograph.\nFigure 1: Chest CT images of a case 7 and case 8 (one pair of 11 month old twins) patient upon admission, who had no symptom. (A) Transverse chest CT images showed pulmonary consolidation and ground glass opacity (case 7 on 7 February). (B) Showed marked improvement after 5 days (case 7 on 13 February). (C) Lung CT of case 8 – the case 7’s younger brother on admission day (case 8 on 7 February).\nTable 2. The laboratory results of nine children patients.\nCase no. WBC (109/L) N (%) L (%) PLT (109/L) Hb (g/L) CRP (mg/L) ESR (mm/h) PCT (ug/L) IL-6 (pg/ml) ALT (U/L) AST (U/L) CK-MB (U/L) CD4 (%) CD8 (%) NK (%) IgM (g/L) IgA (g/L) IgG (g/L) C3 (g/L) C4 (g/L) Ferritin D-dimer Myoglobin (ug/l) BNP (pg/ml) SAA\n1 8.48 32.1 59.9 361 128 0.12 5 0.04 1.5 13 35 34 31.9 34.6 16.5 1.0 0.6 7 0.8 0.2 45.5 0.3 9 133 3\n2 7.55 20.4 73.6 193 120 0.35 2 0.08 1.5 14 33 28 28.3 27.1 27.3 1.2 0.8 7.3 0.8 0.3 33.6 0.3 11 24 4\n3 3.78 38.7 43.9 293 119 0.19 7 0.05 1.5 15 28 23 33.2 35.6 – 1.1 1.6 12.9 1.0 0.2 85.6 0.4 9 29 3\n4 4.14 23.6 69.3 65 129 0.18 6 0.04 1.5 14 28 30 46.6 20.2 8.5 1.1 0.8 6. 9 1.0 0.2 – 0.2 9 116 5\n5 3.69 33.8 53.3 169 106 0.12 5 0.03 1.5 15 23 22 45.7 33.4 14,8 0.9 0.6 8.1 0.1 1.0 48.1 0.1 9 87 3\n6 9.33 27.8 66.7 278 133 0.24 2 0.08 1.5 13 36 76 36.9 22.6 16.7 1.6 1.7 16.3 1.0 0.2 50.7 0.2 9 39 6\n7 11.17 17.2 77.4 305 117 0.19 2 0.04 1.5 22 39 43 – – – 1.3 0.3 7.1 0.7 0.1 62.6 0.3 9 31 3\n8 9.42 24.5 68.6 358 116 0.19 2 0.04 1.5 22 42 52 – – – 0.6 0.2 7.0 0.7 0.1 59.7 0.3 9 2 3\n9 5.45 41.2 53.0 235 140 0.26 3 0.02 1.5 9 24 27 33.1 29.3 16.5 1.3 1. 6 8.9 1.0 0.2 45.6 0.3 18 23 5\nNote: WBC, white blood cell; N, Neutrophil; L, Lymphocyte; PLT, plate; Hb, Hemoglobin; ESR, erythrocyte sedimentation; PCT, Procalcitonin; ALT, alanine aminotransferase; AST, aspartate aminotransferase; CK-MB, creatine kinase MB; IgM, Immunoglobulin M; IgG, Immunoglobulin G; Ig, Immunoglobulin A; C3, complement3; C4, complement4; BNP, N-terminal brain natriuretic peptide precursor; SAA, Serum amyloid A."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T26","span":{"begin":386,"end":396},"obj":"Phenotype"},{"id":"T27","span":{"begin":430,"end":439},"obj":"Phenotype"}],"attributes":[{"id":"A26","pred":"hp_id","subj":"T26","obj":"http://purl.obolibrary.org/obo/HP_0012387"},{"id":"A27","pred":"hp_id","subj":"T27","obj":"http://purl.obolibrary.org/obo/HP_0002090"}],"text":"As shown in Table 2, 8/9 (88.9%) children had normal or decreased white blood cell counts, consistent with the main characteristic of viral infection. Six children (66.7%) showed increased CK-MB. ALT, AST and the other index of liver and kidney were all normal. All inflammation indicators, including CRP, PCT, ESR and IL-6 were all within the normal range. Two children (22.2%) showed bronchitis and one (11.1%) showed bronchial pneumonia. One (11.1%) boy (the older of the twins) showed pulmonary consolidation and ground glass opacity on the first day (Figure 1(A)) admitted in the hospital, and disappeared after five days (Figure 1(B)). Five other (55.6%) children showed no abnormal chest radiograph.\nFigure 1: Chest CT images of a case 7 and case 8 (one pair of 11 month old twins) patient upon admission, who had no symptom. (A) Transverse chest CT images showed pulmonary consolidation and ground glass opacity (case 7 on 7 February). (B) Showed marked improvement after 5 days (case 7 on 13 February). (C) Lung CT of case 8 – the case 7’s younger brother on admission day (case 8 on 7 February).\nTable 2. The laboratory results of nine children patients.\nCase no. WBC (109/L) N (%) L (%) PLT (109/L) Hb (g/L) CRP (mg/L) ESR (mm/h) PCT (ug/L) IL-6 (pg/ml) ALT (U/L) AST (U/L) CK-MB (U/L) CD4 (%) CD8 (%) NK (%) IgM (g/L) IgA (g/L) IgG (g/L) C3 (g/L) C4 (g/L) Ferritin D-dimer Myoglobin (ug/l) BNP (pg/ml) SAA\n1 8.48 32.1 59.9 361 128 0.12 5 0.04 1.5 13 35 34 31.9 34.6 16.5 1.0 0.6 7 0.8 0.2 45.5 0.3 9 133 3\n2 7.55 20.4 73.6 193 120 0.35 2 0.08 1.5 14 33 28 28.3 27.1 27.3 1.2 0.8 7.3 0.8 0.3 33.6 0.3 11 24 4\n3 3.78 38.7 43.9 293 119 0.19 7 0.05 1.5 15 28 23 33.2 35.6 – 1.1 1.6 12.9 1.0 0.2 85.6 0.4 9 29 3\n4 4.14 23.6 69.3 65 129 0.18 6 0.04 1.5 14 28 30 46.6 20.2 8.5 1.1 0.8 6. 9 1.0 0.2 – 0.2 9 116 5\n5 3.69 33.8 53.3 169 106 0.12 5 0.03 1.5 15 23 22 45.7 33.4 14,8 0.9 0.6 8.1 0.1 1.0 48.1 0.1 9 87 3\n6 9.33 27.8 66.7 278 133 0.24 2 0.08 1.5 13 36 76 36.9 22.6 16.7 1.6 1.7 16.3 1.0 0.2 50.7 0.2 9 39 6\n7 11.17 17.2 77.4 305 117 0.19 2 0.04 1.5 22 39 43 – – – 1.3 0.3 7.1 0.7 0.1 62.6 0.3 9 31 3\n8 9.42 24.5 68.6 358 116 0.19 2 0.04 1.5 22 42 52 – – – 0.6 0.2 7.0 0.7 0.1 59.7 0.3 9 2 3\n9 5.45 41.2 53.0 235 140 0.26 3 0.02 1.5 9 24 27 33.1 29.3 16.5 1.3 1. 6 8.9 1.0 0.2 45.6 0.3 18 23 5\nNote: WBC, white blood cell; N, Neutrophil; L, Lymphocyte; PLT, plate; Hb, Hemoglobin; ESR, erythrocyte sedimentation; PCT, Procalcitonin; ALT, alanine aminotransferase; AST, aspartate aminotransferase; CK-MB, creatine kinase MB; IgM, Immunoglobulin M; IgG, Immunoglobulin G; Ig, Immunoglobulin A; C3, complement3; C4, complement4; BNP, N-terminal brain natriuretic peptide precursor; SAA, Serum amyloid A."}

{"project":"LitCovid-PubTator","denotations":[{"id":"195","span":{"begin":789,"end":796},"obj":"Species"},{"id":"203","span":{"begin":1219,"end":1222},"obj":"Gene"},{"id":"204","span":{"begin":1252,"end":1256},"obj":"Gene"},{"id":"205","span":{"begin":1275,"end":1278},"obj":"Gene"},{"id":"206","span":{"begin":1297,"end":1300},"obj":"Gene"},{"id":"207","span":{"begin":1385,"end":1394},"obj":"Gene"},{"id":"208","span":{"begin":1402,"end":1405},"obj":"Gene"},{"id":"209","span":{"begin":1414,"end":1417},"obj":"Gene"},{"id":"212","span":{"begin":1146,"end":1154},"obj":"Species"},{"id":"213","span":{"begin":1155,"end":1163},"obj":"Species"},{"id":"220","span":{"begin":2450,"end":2474},"obj":"Gene"},{"id":"221","span":{"begin":2476,"end":2479},"obj":"Gene"},{"id":"222","span":{"begin":2638,"end":2641},"obj":"Gene"},{"id":"223","span":{"begin":2691,"end":2694},"obj":"Gene"},{"id":"224","span":{"begin":2696,"end":2711},"obj":"Gene"},{"id":"225","span":{"begin":2608,"end":2619},"obj":"Gene"},{"id":"238","span":{"begin":201,"end":204},"obj":"Gene"},{"id":"239","span":{"begin":301,"end":304},"obj":"Gene"},{"id":"240","span":{"begin":319,"end":323},"obj":"Gene"},{"id":"241","span":{"begin":33,"end":41},"obj":"Species"},{"id":"242","span":{"begin":155,"end":163},"obj":"Species"},{"id":"243","span":{"begin":362,"end":370},"obj":"Species"},{"id":"244","span":{"begin":453,"end":456},"obj":"Species"},{"id":"245","span":{"begin":661,"end":669},"obj":"Species"},{"id":"246","span":{"begin":134,"end":149},"obj":"Disease"},{"id":"247","span":{"begin":266,"end":278},"obj":"Disease"},{"id":"248","span":{"begin":386,"end":396},"obj":"Disease"},{"id":"249","span":{"begin":430,"end":439},"obj":"Disease"}],"attributes":[{"id":"A195","pred":"tao:has_database_id","subj":"195","obj":"Tax:9606"},{"id":"A203","pred":"tao:has_database_id","subj":"203","obj":"Gene:1401"},{"id":"A204","pred":"tao:has_database_id","subj":"204","obj":"Gene:3569"},{"id":"A205","pred":"tao:has_database_id","subj":"205","obj":"Gene:26503"},{"id":"A206","pred":"tao:has_database_id","subj":"206","obj":"Gene:920"},{"id":"A207","pred":"tao:has_database_id","subj":"207","obj":"Gene:4151"},{"id":"A208","pred":"tao:has_database_id","subj":"208","obj":"Gene:4879"},{"id":"A209","pred":"tao:has_database_id","subj":"209","obj":"Gene:6287"},{"id":"A212","pred":"tao:has_database_id","subj":"212","obj":"Tax:9606"},{"id":"A213","pred":"tao:has_database_id","subj":"213","obj":"Tax:9606"},{"id":"A220","pred":"tao:has_database_id","subj":"220","obj":"Gene:2875"},{"id":"A221","pred":"tao:has_database_id","subj":"221","obj":"Gene:26503"},{"id":"A222","pred":"tao:has_database_id","subj":"222","obj":"Gene:4879"},{"id":"A223","pred":"tao:has_database_id","subj":"223","obj":"Gene:6287"},{"id":"A224","pred":"tao:has_database_id","subj":"224","obj":"Gene:6287"},{"id":"A225","pred":"tao:has_database_id","subj":"225","obj":"Gene:718"},{"id":"A238","pred":"tao:has_database_id","subj":"238","obj":"Gene:26503"},{"id":"A239","pred":"tao:has_database_id","subj":"239","obj":"Gene:1401"},{"id":"A240","pred":"tao:has_database_id","subj":"240","obj":"Gene:3569"},{"id":"A241","pred":"tao:has_database_id","subj":"241","obj":"Tax:9606"},{"id":"A242","pred":"tao:has_database_id","subj":"242","obj":"Tax:9606"},{"id":"A243","pred":"tao:has_database_id","subj":"243","obj":"Tax:9606"},{"id":"A244","pred":"tao:has_database_id","subj":"244","obj":"Tax:9606"},{"id":"A245","pred":"tao:has_database_id","subj":"245","obj":"Tax:9606"},{"id":"A246","pred":"tao:has_database_id","subj":"246","obj":"MESH:D001102"},{"id":"A247","pred":"tao:has_database_id","subj":"247","obj":"MESH:D007249"},{"id":"A248","pred":"tao:has_database_id","subj":"248","obj":"MESH:D001991"},{"id":"A249","pred":"tao:has_database_id","subj":"249","obj":"MESH:D011014"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"As shown in Table 2, 8/9 (88.9%) children had normal or decreased white blood cell counts, consistent with the main characteristic of viral infection. Six children (66.7%) showed increased CK-MB. ALT, AST and the other index of liver and kidney were all normal. All inflammation indicators, including CRP, PCT, ESR and IL-6 were all within the normal range. Two children (22.2%) showed bronchitis and one (11.1%) showed bronchial pneumonia. One (11.1%) boy (the older of the twins) showed pulmonary consolidation and ground glass opacity on the first day (Figure 1(A)) admitted in the hospital, and disappeared after five days (Figure 1(B)). Five other (55.6%) children showed no abnormal chest radiograph.\nFigure 1: Chest CT images of a case 7 and case 8 (one pair of 11 month old twins) patient upon admission, who had no symptom. (A) Transverse chest CT images showed pulmonary consolidation and ground glass opacity (case 7 on 7 February). (B) Showed marked improvement after 5 days (case 7 on 13 February). (C) Lung CT of case 8 – the case 7’s younger brother on admission day (case 8 on 7 February).\nTable 2. The laboratory results of nine children patients.\nCase no. WBC (109/L) N (%) L (%) PLT (109/L) Hb (g/L) CRP (mg/L) ESR (mm/h) PCT (ug/L) IL-6 (pg/ml) ALT (U/L) AST (U/L) CK-MB (U/L) CD4 (%) CD8 (%) NK (%) IgM (g/L) IgA (g/L) IgG (g/L) C3 (g/L) C4 (g/L) Ferritin D-dimer Myoglobin (ug/l) BNP (pg/ml) SAA\n1 8.48 32.1 59.9 361 128 0.12 5 0.04 1.5 13 35 34 31.9 34.6 16.5 1.0 0.6 7 0.8 0.2 45.5 0.3 9 133 3\n2 7.55 20.4 73.6 193 120 0.35 2 0.08 1.5 14 33 28 28.3 27.1 27.3 1.2 0.8 7.3 0.8 0.3 33.6 0.3 11 24 4\n3 3.78 38.7 43.9 293 119 0.19 7 0.05 1.5 15 28 23 33.2 35.6 – 1.1 1.6 12.9 1.0 0.2 85.6 0.4 9 29 3\n4 4.14 23.6 69.3 65 129 0.18 6 0.04 1.5 14 28 30 46.6 20.2 8.5 1.1 0.8 6. 9 1.0 0.2 – 0.2 9 116 5\n5 3.69 33.8 53.3 169 106 0.12 5 0.03 1.5 15 23 22 45.7 33.4 14,8 0.9 0.6 8.1 0.1 1.0 48.1 0.1 9 87 3\n6 9.33 27.8 66.7 278 133 0.24 2 0.08 1.5 13 36 76 36.9 22.6 16.7 1.6 1.7 16.3 1.0 0.2 50.7 0.2 9 39 6\n7 11.17 17.2 77.4 305 117 0.19 2 0.04 1.5 22 39 43 – – – 1.3 0.3 7.1 0.7 0.1 62.6 0.3 9 31 3\n8 9.42 24.5 68.6 358 116 0.19 2 0.04 1.5 22 42 52 – – – 0.6 0.2 7.0 0.7 0.1 59.7 0.3 9 2 3\n9 5.45 41.2 53.0 235 140 0.26 3 0.02 1.5 9 24 27 33.1 29.3 16.5 1.3 1. 6 8.9 1.0 0.2 45.6 0.3 18 23 5\nNote: WBC, white blood cell; N, Neutrophil; L, Lymphocyte; PLT, plate; Hb, Hemoglobin; ESR, erythrocyte sedimentation; PCT, Procalcitonin; ALT, alanine aminotransferase; AST, aspartate aminotransferase; CK-MB, creatine kinase MB; IgM, Immunoglobulin M; IgG, Immunoglobulin G; Ig, Immunoglobulin A; C3, complement3; C4, complement4; BNP, N-terminal brain natriuretic peptide precursor; SAA, Serum amyloid A."}