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{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7103696","sourcedb":"PMC","sourceid":"7103696","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7103696","text":"Since late 2019 to early 2020, the sudden outbreak of COVID-19, among the general human population in the City of Wuhan, caused by the transmission of a novel coronavirus, SARS-CoV-2 [1,2], has led to over 80,000 diagnosed cases including more than 3000 deaths globally as of 29 February 2020. While the overall mortality rate for SARS-CoV-2 seems lower than SARS or MERS, the death rate among severe cases infected by SARS-CoV-2 is alarming. There are a wide range of efforts to develop special treatments for COVID-19 with limited success. In the current commentary, EMI invited three leading infectious disease experts in China who have personally participated in the clinical management of COVID-19 cases to share their bedside observations and to suggest what may be important in formulating the treatment strategy to optimize the clinical 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