PMC:7102583 / 15084-15413 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"600","span":{"begin":40,"end":45},"obj":"Gene"},{"id":"601","span":{"begin":297,"end":302},"obj":"Gene"},{"id":"606","span":{"begin":16,"end":25},"obj":"Chemical"},{"id":"607","span":{"begin":129,"end":135},"obj":"Chemical"},{"id":"608","span":{"begin":185,"end":194},"obj":"Chemical"},{"id":"618","span":{"begin":83,"end":94},"obj":"Disease"},{"id":"619","span":{"begin":96,"end":124},"obj":"Disease"}],"attributes":[{"id":"A600","pred":"tao:has_database_id","subj":"600","obj":"Gene:114548"},{"id":"A601","pred":"tao:has_database_id","subj":"601","obj":"Gene:114548"},{"id":"A606","pred":"tao:has_database_id","subj":"606","obj":"MESH:D008550"},{"id":"A607","pred":"tao:has_database_id","subj":"607","obj":"MESH:D010100"},{"id":"A608","pred":"tao:has_database_id","subj":"608","obj":"MESH:D008550"},{"id":"A618","pred":"tao:has_database_id","subj":"618","obj":"MESH:D055370"},{"id":"A619","pred":"tao:has_database_id","subj":"619","obj":"MESH:D007249"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"The efficacy of melatonin in regulating NLRP3 has been proven in radiation-induced lung injury, allergic airway inflammation and oxygen-induced ALI and LPS-induced ALI models, in which melatonin reduced the infiltration of macrophages and neutrophils into the lung in ALI due to the inhibition of NLRP3 inflammasome [4,28,54,55]."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T158","span":{"begin":16,"end":25},"obj":"Body_part"},{"id":"T159","span":{"begin":83,"end":87},"obj":"Body_part"},{"id":"T160","span":{"begin":185,"end":194},"obj":"Body_part"},{"id":"T161","span":{"begin":223,"end":234},"obj":"Body_part"},{"id":"T162","span":{"begin":239,"end":250},"obj":"Body_part"},{"id":"T163","span":{"begin":260,"end":264},"obj":"Body_part"}],"attributes":[{"id":"A158","pred":"fma_id","subj":"T158","obj":"http://purl.org/sig/ont/fma/fma74644"},{"id":"A159","pred":"fma_id","subj":"T159","obj":"http://purl.org/sig/ont/fma/fma7195"},{"id":"A160","pred":"fma_id","subj":"T160","obj":"http://purl.org/sig/ont/fma/fma74644"},{"id":"A161","pred":"fma_id","subj":"T161","obj":"http://purl.org/sig/ont/fma/fma63261"},{"id":"A162","pred":"fma_id","subj":"T162","obj":"http://purl.org/sig/ont/fma/fma62860"},{"id":"A163","pred":"fma_id","subj":"T163","obj":"http://purl.org/sig/ont/fma/fma7195"}],"text":"The efficacy of melatonin in regulating NLRP3 has been proven in radiation-induced lung injury, allergic airway inflammation and oxygen-induced ALI and LPS-induced ALI models, in which melatonin reduced the infiltration of macrophages and neutrophils into the lung in ALI due to the inhibition of NLRP3 inflammasome [4,28,54,55]."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T36","span":{"begin":83,"end":87},"obj":"Body_part"},{"id":"T37","span":{"begin":260,"end":264},"obj":"Body_part"}],"attributes":[{"id":"A36","pred":"uberon_id","subj":"T36","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"A37","pred":"uberon_id","subj":"T37","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"}],"text":"The efficacy of melatonin in regulating NLRP3 has been proven in radiation-induced lung injury, allergic airway inflammation and oxygen-induced ALI and LPS-induced ALI models, in which melatonin reduced the infiltration of macrophages and neutrophils into the lung in ALI due to the inhibition of NLRP3 inflammasome [4,28,54,55]."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T164","span":{"begin":88,"end":94},"obj":"Disease"},{"id":"T165","span":{"begin":96,"end":104},"obj":"Disease"},{"id":"T166","span":{"begin":112,"end":124},"obj":"Disease"},{"id":"T167","span":{"begin":144,"end":147},"obj":"Disease"},{"id":"T168","span":{"begin":164,"end":167},"obj":"Disease"},{"id":"T169","span":{"begin":268,"end":271},"obj":"Disease"}],"attributes":[{"id":"A164","pred":"mondo_id","subj":"T164","obj":"http://purl.obolibrary.org/obo/MONDO_0021178"},{"id":"A165","pred":"mondo_id","subj":"T165","obj":"http://purl.obolibrary.org/obo/MONDO_0004980"},{"id":"A166","pred":"mondo_id","subj":"T166","obj":"http://purl.obolibrary.org/obo/MONDO_0021166"},{"id":"A167","pred":"mondo_id","subj":"T167","obj":"http://purl.obolibrary.org/obo/MONDO_0006502"},{"id":"A168","pred":"mondo_id","subj":"T168","obj":"http://purl.obolibrary.org/obo/MONDO_0006502"},{"id":"A169","pred":"mondo_id","subj":"T169","obj":"http://purl.obolibrary.org/obo/MONDO_0006502"}],"text":"The efficacy of melatonin in regulating NLRP3 has been proven in radiation-induced lung injury, allergic airway inflammation and oxygen-induced ALI and LPS-induced ALI models, in which melatonin reduced the infiltration of macrophages and neutrophils into the lung in ALI due to the inhibition of NLRP3 inflammasome [4,28,54,55]."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T201","span":{"begin":46,"end":49},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T202","span":{"begin":83,"end":87},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T203","span":{"begin":83,"end":87},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T204","span":{"begin":105,"end":111},"obj":"http://purl.obolibrary.org/obo/UBERON_0001005"},{"id":"T205","span":{"begin":260,"end":264},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T206","span":{"begin":260,"end":264},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"}],"text":"The efficacy of melatonin in regulating NLRP3 has been proven in radiation-induced lung injury, allergic airway inflammation and oxygen-induced ALI and LPS-induced ALI models, in which melatonin reduced the infiltration of macrophages and neutrophils into the lung in ALI due to the inhibition of NLRP3 inflammasome [4,28,54,55]."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T147","span":{"begin":16,"end":25},"obj":"Chemical"},{"id":"T148","span":{"begin":129,"end":135},"obj":"Chemical"},{"id":"T149","span":{"begin":152,"end":155},"obj":"Chemical"},{"id":"T152","span":{"begin":185,"end":194},"obj":"Chemical"}],"attributes":[{"id":"A147","pred":"chebi_id","subj":"T147","obj":"http://purl.obolibrary.org/obo/CHEBI_16796"},{"id":"A148","pred":"chebi_id","subj":"T148","obj":"http://purl.obolibrary.org/obo/CHEBI_25805"},{"id":"A149","pred":"chebi_id","subj":"T149","obj":"http://purl.obolibrary.org/obo/CHEBI_16412"},{"id":"A150","pred":"chebi_id","subj":"T149","obj":"http://purl.obolibrary.org/obo/CHEBI_52603"},{"id":"A151","pred":"chebi_id","subj":"T149","obj":"http://purl.obolibrary.org/obo/CHEBI_89981"},{"id":"A152","pred":"chebi_id","subj":"T152","obj":"http://purl.obolibrary.org/obo/CHEBI_16796"}],"text":"The efficacy of melatonin in regulating NLRP3 has been proven in radiation-induced lung injury, allergic airway inflammation and oxygen-induced ALI and LPS-induced ALI models, in which melatonin reduced the infiltration of macrophages and neutrophils into the lung in ALI due to the inhibition of NLRP3 inflammasome [4,28,54,55]."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T71","span":{"begin":112,"end":124},"obj":"http://purl.obolibrary.org/obo/GO_0006954"}],"text":"The efficacy of melatonin in regulating NLRP3 has been proven in radiation-induced lung injury, allergic airway inflammation and oxygen-induced ALI and LPS-induced ALI models, in which melatonin reduced the infiltration of macrophages and neutrophils into the lung in ALI due to the inhibition of NLRP3 inflammasome [4,28,54,55]."}

{"project":"LitCovid-sentences","denotations":[{"id":"T105","span":{"begin":0,"end":329},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"The efficacy of melatonin in regulating NLRP3 has been proven in radiation-induced lung injury, allergic airway inflammation and oxygen-induced ALI and LPS-induced ALI models, in which melatonin reduced the infiltration of macrophages and neutrophils into the lung in ALI due to the inhibition of NLRP3 inflammasome [4,28,54,55]."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T72","span":{"begin":144,"end":147},"obj":"Phenotype"},{"id":"T73","span":{"begin":164,"end":167},"obj":"Phenotype"},{"id":"T74","span":{"begin":268,"end":271},"obj":"Phenotype"}],"attributes":[{"id":"A72","pred":"hp_id","subj":"T72","obj":"http://www.orpha.net/ORDO/Orphanet_178320"},{"id":"A73","pred":"hp_id","subj":"T73","obj":"http://www.orpha.net/ORDO/Orphanet_178320"},{"id":"A74","pred":"hp_id","subj":"T74","obj":"http://www.orpha.net/ORDO/Orphanet_178320"}],"text":"The efficacy of melatonin in regulating NLRP3 has been proven in radiation-induced lung injury, allergic airway inflammation and oxygen-induced ALI and LPS-induced ALI models, in which melatonin reduced the infiltration of macrophages and neutrophils into the lung in ALI due to the inhibition of NLRP3 inflammasome [4,28,54,55]."}

{"project":"2_test","denotations":[{"id":"32217117-25491480-66453511","span":{"begin":319,"end":321},"obj":"25491480"},{"id":"32217117-31738882-66453512","span":{"begin":322,"end":324},"obj":"31738882"},{"id":"32217117-26888116-66453513","span":{"begin":325,"end":327},"obj":"26888116"}],"text":"The efficacy of melatonin in regulating NLRP3 has been proven in radiation-induced lung injury, allergic airway inflammation and oxygen-induced ALI and LPS-induced ALI models, in which melatonin reduced the infiltration of macrophages and neutrophils into the lung in ALI due to the inhibition of NLRP3 inflammasome [4,28,54,55]."}