PMC:7102551 / 2862-3547
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7102551","sourcedb":"PMC","sourceid":"7102551","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7102551","text":"This postulate isn’t novel as it has been found and characterized in the SARS coronavirus, SARS-CoV. Enhancement was identified by Yang et al. [6] in 2005 and was hypothesized as being the reason for such a high mortality rate in China [7]. At the time, the priming strains were thought to be human coronaviruses known to cause mild infection such as 229E [7]. The mechanism was characterized by Yip et al. [8,9] and revealed that anti-Spike protein antibodies were indeed responsible for the infection of immune cells. Wang et al. [10] revealed that enhancement may be improved by increasing dilutions of antibodies, suggesting a temporal relationship between priming and 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