PMC:7102551 / 2862-3547 JSONTXT

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T133","span":{"begin":73,"end":77},"obj":"SP_10"},{"id":"T132","span":{"begin":78,"end":89},"obj":"NCBITaxon:11118"},{"id":"T131","span":{"begin":91,"end":99},"obj":"SP_10"},{"id":"T130","span":{"begin":293,"end":298},"obj":"SP_6;NCBITaxon:9606"},{"id":"T129","span":{"begin":299,"end":312},"obj":"NCBITaxon:11118"},{"id":"T128","span":{"begin":450,"end":460},"obj":"GO:0042571"},{"id":"T127","span":{"begin":506,"end":512},"obj":"UBERON:0002405;CL:0000738"},{"id":"T126","span":{"begin":513,"end":518},"obj":"CL:0000738"},{"id":"T125","span":{"begin":606,"end":616},"obj":"GO:0042571"}],"text":"This postulate isn’t novel as it has been found and characterized in the SARS coronavirus, SARS-CoV. Enhancement was identified by Yang et al. [6] in 2005 and was hypothesized as being the reason for such a high mortality rate in China [7]. At the time, the priming strains were thought to be human coronaviruses known to cause mild infection such as 229E [7]. The mechanism was characterized by Yip et al. [8,9] and revealed that anti-Spike protein antibodies were indeed responsible for the infection of immune cells. Wang et al. [10] revealed that enhancement may be improved by increasing dilutions of antibodies, suggesting a temporal relationship between priming and enhancement."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T5","span":{"begin":442,"end":449},"obj":"Body_part"},{"id":"T6","span":{"begin":513,"end":518},"obj":"Body_part"}],"attributes":[{"id":"A5","pred":"fma_id","subj":"T5","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A6","pred":"fma_id","subj":"T6","obj":"http://purl.org/sig/ont/fma/fma68646"}],"text":"This postulate isn’t novel as it has been found and characterized in the SARS coronavirus, SARS-CoV. Enhancement was identified by Yang et al. [6] in 2005 and was hypothesized as being the reason for such a high mortality rate in China [7]. At the time, the priming strains were thought to be human coronaviruses known to cause mild infection such as 229E [7]. The mechanism was characterized by Yip et al. [8,9] and revealed that anti-Spike protein antibodies were indeed responsible for the infection of immune cells. Wang et al. [10] revealed that enhancement may be improved by increasing dilutions of antibodies, suggesting a temporal relationship between priming and enhancement."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T28","span":{"begin":73,"end":77},"obj":"Disease"},{"id":"T29","span":{"begin":91,"end":99},"obj":"Disease"},{"id":"T30","span":{"begin":91,"end":95},"obj":"Disease"},{"id":"T31","span":{"begin":333,"end":342},"obj":"Disease"},{"id":"T32","span":{"begin":493,"end":502},"obj":"Disease"}],"attributes":[{"id":"A28","pred":"mondo_id","subj":"T28","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A29","pred":"mondo_id","subj":"T29","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A30","pred":"mondo_id","subj":"T30","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A31","pred":"mondo_id","subj":"T31","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A32","pred":"mondo_id","subj":"T32","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"}],"text":"This postulate isn’t novel as it has been found and characterized in the SARS coronavirus, SARS-CoV. Enhancement was identified by Yang et al. [6] in 2005 and was hypothesized as being the reason for such a high mortality rate in China [7]. At the time, the priming strains were thought to be human coronaviruses known to cause mild infection such as 229E [7]. The mechanism was characterized by Yip et al. [8,9] and revealed that anti-Spike protein antibodies were indeed responsible for the infection of immune cells. Wang et al. [10] revealed that enhancement may be improved by increasing dilutions of antibodies, suggesting a temporal relationship between priming and enhancement."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T19","span":{"begin":33,"end":36},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T20","span":{"begin":205,"end":206},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T21","span":{"begin":290,"end":298},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T22","span":{"begin":513,"end":518},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T23","span":{"begin":629,"end":630},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"This postulate isn’t novel as it has been found and characterized in the SARS coronavirus, SARS-CoV. Enhancement was identified by Yang et al. [6] in 2005 and was hypothesized as being the reason for such a high mortality rate in China [7]. At the time, the priming strains were thought to be human coronaviruses known to cause mild infection such as 229E [7]. The mechanism was characterized by Yip et al. [8,9] and revealed that anti-Spike protein antibodies were indeed responsible for the infection of immune cells. Wang et al. [10] revealed that enhancement may be improved by increasing dilutions of antibodies, suggesting a temporal relationship between priming and enhancement."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T2","span":{"begin":442,"end":449},"obj":"Chemical"}],"attributes":[{"id":"A2","pred":"chebi_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"}],"text":"This postulate isn’t novel as it has been found and characterized in the SARS coronavirus, SARS-CoV. Enhancement was identified by Yang et al. [6] in 2005 and was hypothesized as being the reason for such a high mortality rate in China [7]. At the time, the priming strains were thought to be human coronaviruses known to cause mild infection such as 229E [7]. The mechanism was characterized by Yip et al. [8,9] and revealed that anti-Spike protein antibodies were indeed responsible for the infection of immune cells. Wang et al. [10] revealed that enhancement may be improved by increasing dilutions of antibodies, suggesting a temporal relationship between priming and enhancement."}

{"project":"LitCovid-sentences","denotations":[{"id":"T23","span":{"begin":0,"end":100},"obj":"Sentence"},{"id":"T24","span":{"begin":101,"end":240},"obj":"Sentence"},{"id":"T25","span":{"begin":241,"end":360},"obj":"Sentence"},{"id":"T26","span":{"begin":361,"end":519},"obj":"Sentence"},{"id":"T27","span":{"begin":520,"end":685},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"This postulate isn’t novel as it has been found and characterized in the SARS coronavirus, SARS-CoV. Enhancement was identified by Yang et al. [6] in 2005 and was hypothesized as being the reason for such a high mortality rate in China [7]. At the time, the priming strains were thought to be human coronaviruses known to cause mild infection such as 229E [7]. The mechanism was characterized by Yip et al. [8,9] and revealed that anti-Spike protein antibodies were indeed responsible for the infection of immune cells. Wang et al. [10] revealed that enhancement may be improved by increasing dilutions of antibodies, suggesting a temporal relationship between priming and enhancement."}

{"project":"LitCovid-PubTator","denotations":[{"id":"72","span":{"begin":436,"end":441},"obj":"Gene"},{"id":"73","span":{"begin":73,"end":89},"obj":"Species"},{"id":"74","span":{"begin":91,"end":99},"obj":"Species"},{"id":"75","span":{"begin":293,"end":298},"obj":"Species"},{"id":"76","span":{"begin":299,"end":312},"obj":"Species"},{"id":"77","span":{"begin":212,"end":221},"obj":"Disease"},{"id":"78","span":{"begin":333,"end":342},"obj":"Disease"},{"id":"79","span":{"begin":493,"end":502},"obj":"Disease"}],"attributes":[{"id":"A72","pred":"tao:has_database_id","subj":"72","obj":"Gene:43740568"},{"id":"A73","pred":"tao:has_database_id","subj":"73","obj":"Tax:694009"},{"id":"A74","pred":"tao:has_database_id","subj":"74","obj":"Tax:694009"},{"id":"A75","pred":"tao:has_database_id","subj":"75","obj":"Tax:9606"},{"id":"A76","pred":"tao:has_database_id","subj":"76","obj":"Tax:11118"},{"id":"A77","pred":"tao:has_database_id","subj":"77","obj":"MESH:D003643"},{"id":"A78","pred":"tao:has_database_id","subj":"78","obj":"MESH:D007239"},{"id":"A79","pred":"tao:has_database_id","subj":"79","obj":"MESH:D007239"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"This postulate isn’t novel as it has been found and characterized in the SARS coronavirus, SARS-CoV. Enhancement was identified by Yang et al. [6] in 2005 and was hypothesized as being the reason for such a high mortality rate in China [7]. At the time, the priming strains were thought to be human coronaviruses known to cause mild infection such as 229E [7]. The mechanism was characterized by Yip et al. [8,9] and revealed that anti-Spike protein antibodies were indeed responsible for the infection of immune cells. Wang et al. [10] revealed that enhancement may be improved by increasing dilutions of antibodies, suggesting a temporal relationship between priming and enhancement."}