PMC:7091888 / 9890-13134 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7091888","sourcedb":"PMC","sourceid":"7091888","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7091888","text":"Fig. 2 Detection of SARS-CoV-2 RBD binding to human ACE2 receptor. a Flow cytometry analysis of receptor expression in stable cell lines. (left panel) 293T cells alone expressed neither human ACE2 (hACE2) receptor (orange line) nor hDPP4 receptor (cyan line); (middle panel) hACE2-expressing 293T (hACE2/293T) cells expressed only hACE2 (orange line), but not hDPP4 (cyan line); (right panel) hDPP4-expressing 293T (hDPP4/293T) cells expressed only hDPP4 (cyan line), but not hACE2 (orange line). Mock-incubated cells (gray shading) were used as control. Representative images and median fluorescence intensity (MFI) ± standard error (s.e.m.) were shown (n = 4). b, c Flow cytometry analysis of SARS-CoV-2 RBD binding to cell-associated hACE2 receptor in hACE2/293T stable cell lines. SARS-CoV-2 RBD protein bound strongly to hACE2/293T cells (b (left panel, red line)), but not to hDPP4/293T cells (c (left panel, violet line)). SARS-CoV RBD protein bound to hACE2/293T cells (b (middle panel, red line)), but not to hDPP4/293T cells (c (middle panel, violet line)). MERS-CoV RBD protein did not bind to hACE2/293T cells (b (right panel, red line)), but rather bound to hDPP4/293T cells (c (right panel, violet line)). Human IgG Fc (hIgG-Fc, hereinafter hFc) protein-incubated cells (blue line) and mock-incubated cells (gray shading) were included as controls (b, c). Representative images and MFI ± s.e.m. were shown (n = 4). d Immunofluorescence detection of SARS-CoV-2 RBD binding to cell-associated hACE2 receptor in hACE2/293T cells. SARS-CoV-2 RBD protein (green) and SARS-CoV RBD protein (green), each of which was fused with a C-terminal hFc, were stained with FITC-labeled goat anti-human IgG antibody (1:500). hACE2 was stained with a goat-anti-hACE2 antibody (5 μg/ml) and Alexa-Fluor 647-labeled anti-goat antibody (red) (1:200). Fc-fused MERS-CoV RBD protein did not bind to hACE2, so only hACE2 (red), but not RBD (green), was detected in hACE2/293T cells. Nuclei were stained with 4’,6-diamidino-2-phenylindole (DAPI, blue). Scale bar: 10 μm. Representative images are shown. e Detection of dose-dependent binding of SARS-CoV-2 RBD protein to soluble hACE2 (sACE2) receptor by ELISA. The SARS-CoV-2 RBD binding to soluble hDPP4 (sDPP4) receptor (f), and the binding of both SARS-CoV RBD and MERS-CoV RBD proteins to sACE2 (e), or sDPP4 (f), were tested. Control: hFc protein. Data are presented as mean A450 ± s.e.m. (n = 4). 50% effective dose (EC50) was calculated for the binding between SARS-CoV-2 RBD (black) or SARS-CoV RBD (red) and hACE2 protein (e, sACE2), or the binding between MERS-CoV RBD and hDPP4 protein (sDPP4, green) (f). g–i Flow cytometry analysis of inhibition of SARS-CoV-2 RBD protein binding to hACE2/293T cells by sACE2. Binding of SARS-CoV-2 RBD to hACE2/293T cells (g, h, green line) was blocked by sACE2 (g, black line), but not by sDPP4 (h, red line). hFc protein-incubated cells (blue line) and mock-incubated cells (gray shading) were included as controls (g, h). Representative images are shown. i The blocking ability of sACE2 or sDPP4, as described above, was expressed as MFI ± s.e.m. (n = 4). Low MFI correlates with high blockage. Experiments were repeated twice and yielded similar results","divisions":[{"label":"label","span":{"begin":0,"end":6}}],"tracks":[{"project":"LitCovid-PubTator","denotations":[{"id":"329","span":{"begin":52,"end":56},"obj":"Gene"},{"id":"330","span":{"begin":192,"end":196},"obj":"Gene"},{"id":"331","span":{"begin":198,"end":203},"obj":"Gene"},{"id":"332","span":{"begin":232,"end":237},"obj":"Gene"},{"id":"333","span":{"begin":298,"end":308},"obj":"Gene"},{"id":"334","span":{"begin":331,"end":336},"obj":"Gene"},{"id":"335","span":{"begin":360,"end":365},"obj":"Gene"},{"id":"336","span":{"begin":416,"end":426},"obj":"Gene"},{"id":"337","span":{"begin":449,"end":454},"obj":"Gene"},{"id":"338","span":{"begin":476,"end":481},"obj":"Gene"},{"id":"339","span":{"begin":737,"end":742},"obj":"Gene"},{"id":"340","span":{"begin":755,"end":765},"obj":"Gene"},{"id":"341","span":{"begin":826,"end":831},"obj":"Gene"},{"id":"342","span":{"begin":960,"end":965},"obj":"Gene"},{"id":"343","span":{"begin":1105,"end":1110},"obj":"Gene"},{"id":"344","span":{"begin":1505,"end":1510},"obj":"Gene"},{"id":"345","span":{"begin":1523,"end":1533},"obj":"Gene"},{"id":"346","span":{"begin":1722,"end":1727},"obj":"Gene"},{"id":"347","span":{"begin":1757,"end":1762},"obj":"Gene"},{"id":"348","span":{"begin":1890,"end":1895},"obj":"Gene"},{"id":"349","span":{"begin":1905,"end":1910},"obj":"Gene"},{"id":"350","span":{"begin":1955,"end":1960},"obj":"Gene"},{"id":"351","span":{"begin":2168,"end":2173},"obj":"Gene"},{"id":"352","span":{"begin":2557,"end":2562},"obj":"Gene"},{"id":"353","span":{"begin":2623,"end":2628},"obj":"Gene"},{"id":"354","span":{"begin":2736,"end":2741},"obj":"Gene"},{"id":"355","span":{"begin":2792,"end":2797},"obj":"Gene"},{"id":"356","span":{"begin":20,"end":30},"obj":"Species"},{"id":"357","span":{"begin":46,"end":51},"obj":"Species"},{"id":"358","span":{"begin":186,"end":191},"obj":"Species"},{"id":"359","span":{"begin":695,"end":705},"obj":"Species"},{"id":"360","span":{"begin":785,"end":795},"obj":"Species"},{"id":"361","span":{"begin":930,"end":938},"obj":"Species"},{"id":"362","span":{"begin":1463,"end":1473},"obj":"Species"},{"id":"363","span":{"begin":1541,"end":1551},"obj":"Species"},{"id":"364","span":{"begin":1576,"end":1584},"obj":"Species"},{"id":"365","span":{"begin":2134,"end":2144},"obj":"Species"},{"id":"366","span":{"begin":2205,"end":2215},"obj":"Species"},{"id":"367","span":{"begin":2291,"end":2299},"obj":"Species"},{"id":"368","span":{"begin":2308,"end":2316},"obj":"Species"},{"id":"369","span":{"begin":2508,"end":2518},"obj":"Species"},{"id":"370","span":{"begin":2534,"end":2542},"obj":"Species"},{"id":"371","span":{"begin":2702,"end":2712},"obj":"Species"},{"id":"372","span":{"begin":2774,"end":2784},"obj":"Species"},{"id":"373","span":{"begin":1220,"end":1225},"obj":"Species"},{"id":"374","span":{"begin":1694,"end":1699},"obj":"Species"},{"id":"375","span":{"begin":2239,"end":2244},"obj":"Gene"},{"id":"376","span":{"begin":1671,"end":1675},"obj":"Chemical"},{"id":"377","span":{"begin":1786,"end":1801},"obj":"Chemical"},{"id":"378","span":{"begin":1998,"end":2027},"obj":"Chemical"},{"id":"379","span":{"begin":2029,"end":2033},"obj":"Chemical"},{"id":"380","span":{"begin":151,"end":155},"obj":"CellLine"},{"id":"381","span":{"begin":292,"end":296},"obj":"CellLine"},{"id":"382","span":{"begin":410,"end":414},"obj":"CellLine"},{"id":"383","span":{"begin":832,"end":836},"obj":"CellLine"},{"id":"384","span":{"begin":888,"end":892},"obj":"CellLine"},{"id":"385","span":{"begin":966,"end":970},"obj":"CellLine"},{"id":"386","span":{"begin":1024,"end":1028},"obj":"CellLine"},{"id":"387","span":{"begin":1111,"end":1115},"obj":"CellLine"},{"id":"388","span":{"begin":1177,"end":1181},"obj":"CellLine"},{"id":"389","span":{"begin":1961,"end":1965},"obj":"CellLine"},{"id":"390","span":{"begin":2742,"end":2746},"obj":"CellLine"},{"id":"391","span":{"begin":2798,"end":2802},"obj":"CellLine"}],"attributes":[{"id":"A329","pred":"tao:has_database_id","subj":"329","obj":"Gene:59272"},{"id":"A330","pred":"tao:has_database_id","subj":"330","obj":"Gene:59272"},{"id":"A331","pred":"tao:has_database_id","subj":"331","obj":"Gene:59272"},{"id":"A332","pred":"tao:has_database_id","subj":"332","obj":"Gene:1803"},{"id":"A333","pred":"tao:has_database_id","subj":"333","obj":"Gene:59272"},{"id":"A334","pred":"tao:has_database_id","subj":"334","obj":"Gene:59272"},{"id":"A335","pred":"tao:has_database_id","subj":"335","obj":"Gene:1803"},{"id":"A336","pred":"tao:has_database_id","subj":"336","obj":"Gene:1803"},{"id":"A337","pred":"tao:has_database_id","subj":"337","obj":"Gene:1803"},{"id":"A338","pred":"tao:has_database_id","subj":"338","obj":"Gene:59272"},{"id":"A339","pred":"tao:has_database_id","subj":"339","obj":"Gene:59272"},{"id":"A340","pred":"tao:has_database_id","subj":"340","obj":"Gene:59272"},{"id":"A341","pred":"tao:has_database_id","subj":"341","obj":"Gene:59272"},{"id":"A342","pred":"tao:has_database_id","subj":"342","obj":"Gene:59272"},{"id":"A343","pred":"tao:has_database_id","subj":"343","obj":"Gene:59272"},{"id":"A344","pred":"tao:has_database_id","subj":"344","obj":"Gene:59272"},{"id":"A345","pred":"tao:has_database_id","subj":"345","obj":"Gene:59272"},{"id":"A346","pred":"tao:has_database_id","subj":"346","obj":"Gene:59272"},{"id":"A347","pred":"tao:has_database_id","subj":"347","obj":"Gene:59272"},{"id":"A348","pred":"tao:has_database_id","subj":"348","obj":"Gene:59272"},{"id":"A349","pred":"tao:has_database_id","subj":"349","obj":"Gene:59272"},{"id":"A350","pred":"tao:has_database_id","subj":"350","obj":"Gene:59272"},{"id":"A351","pred":"tao:has_database_id","subj":"351","obj":"Gene:59272"},{"id":"A352","pred":"tao:has_database_id","subj":"352","obj":"Gene:59272"},{"id":"A353","pred":"tao:has_database_id","subj":"353","obj":"Gene:1803"},{"id":"A354","pred":"tao:has_database_id","subj":"354","obj":"Gene:59272"},{"id":"A355","pred":"tao:has_database_id","subj":"355","obj":"Gene:59272"},{"id":"A356","pred":"tao:has_database_id","subj":"356","obj":"Tax:2697049"},{"id":"A357","pred":"tao:has_database_id","subj":"357","obj":"Tax:9606"},{"id":"A358","pred":"tao:has_database_id","subj":"358","obj":"Tax:9606"},{"id":"A359","pred":"tao:has_database_id","subj":"359","obj":"Tax:2697049"},{"id":"A360","pred":"tao:has_database_id","subj":"360","obj":"Tax:2697049"},{"id":"A361","pred":"tao:has_database_id","subj":"361","obj":"Tax:694009"},{"id":"A362","pred":"tao:has_database_id","subj":"362","obj":"Tax:2697049"},{"id":"A363","pred":"tao:has_database_id","subj":"363","obj":"Tax:2697049"},{"id":"A364","pred":"tao:has_database_id","subj":"364","obj":"Tax:694009"},{"id":"A365","pred":"tao:has_database_id","subj":"365","obj":"Tax:2697049"},{"id":"A366","pred":"tao:has_database_id","subj":"366","obj":"Tax:2697049"},{"id":"A367","pred":"tao:has_database_id","subj":"367","obj":"Tax:694009"},{"id":"A368","pred":"tao:has_database_id","subj":"368","obj":"Tax:1335626"},{"id":"A369","pred":"tao:has_database_id","subj":"369","obj":"Tax:2697049"},{"id":"A370","pred":"tao:has_database_id","subj":"370","obj":"Tax:694009"},{"id":"A371","pred":"tao:has_database_id","subj":"371","obj":"Tax:2697049"},{"id":"A372","pred":"tao:has_database_id","subj":"372","obj":"Tax:2697049"},{"id":"A373","pred":"tao:has_database_id","subj":"373","obj":"Tax:9606"},{"id":"A374","pred":"tao:has_database_id","subj":"374","obj":"Tax:9606"},{"id":"A375","pred":"tao:has_database_id","subj":"375","obj":"Gene:1803"},{"id":"A376","pred":"tao:has_database_id","subj":"376","obj":"MESH:D016650"},{"id":"A377","pred":"tao:has_database_id","subj":"377","obj":"MESH:C569686"},{"id":"A378","pred":"tao:has_database_id","subj":"378","obj":"MESH:C007293"},{"id":"A379","pred":"tao:has_database_id","subj":"379","obj":"MESH:C007293"},{"id":"A380","pred":"tao:has_database_id","subj":"380","obj":"CVCL:0063"},{"id":"A381","pred":"tao:has_database_id","subj":"381","obj":"CVCL:0063"},{"id":"A382","pred":"tao:has_database_id","subj":"382","obj":"CVCL:0063"},{"id":"A383","pred":"tao:has_database_id","subj":"383","obj":"CVCL:0063"},{"id":"A384","pred":"tao:has_database_id","subj":"384","obj":"CVCL:0063"},{"id":"A385","pred":"tao:has_database_id","subj":"385","obj":"CVCL:0063"},{"id":"A386","pred":"tao:has_database_id","subj":"386","obj":"CVCL:0063"},{"id":"A387","pred":"tao:has_database_id","subj":"387","obj":"CVCL:0063"},{"id":"A388","pred":"tao:has_database_id","subj":"388","obj":"CVCL:0063"},{"id":"A389","pred":"tao:has_database_id","subj":"389","obj":"CVCL:0063"},{"id":"A390","pred":"tao:has_database_id","subj":"390","obj":"CVCL:0063"},{"id":"A391","pred":"tao:has_database_id","subj":"391","obj":"CVCL:0063"},{"subj":"329","pred":"source","obj":"LitCovid-PubTator"},{"subj":"330","pred":"source","obj":"LitCovid-PubTator"},{"subj":"331","pred":"source","obj":"LitCovid-PubTator"},{"subj":"332","pred":"source","obj":"LitCovid-PubTator"},{"subj":"333","pred":"source","obj":"LitCovid-PubTator"},{"subj":"334","pred":"source","obj":"LitCovid-PubTator"},{"subj":"335","pred":"source","obj":"LitCovid-PubTator"},{"subj":"336","pred":"source","obj":"LitCovid-PubTator"},{"subj":"337","pred":"source","obj":"LitCovid-PubTator"},{"subj":"338","pred":"source","obj":"LitCovid-PubTator"},{"subj":"339","pred":"source","obj":"LitCovid-PubTator"},{"subj":"340","pred":"source","obj":"LitCovid-PubTator"},{"subj":"341","pred":"source","obj":"LitCovid-PubTator"},{"subj":"342","pred":"source","obj":"LitCovid-PubTator"},{"subj":"343","pred":"source","obj":"LitCovid-PubTator"},{"subj":"344","pred":"source","obj":"LitCovid-PubTator"},{"subj":"345","pred":"source","obj":"LitCovid-PubTator"},{"subj":"346","pred":"source","obj":"LitCovid-PubTator"},{"subj":"347","pred":"source","obj":"LitCovid-PubTator"},{"subj":"348","pred":"source","obj":"LitCovid-PubTator"},{"subj":"349","pred":"source","obj":"LitCovid-PubTator"},{"subj":"350","pred":"source","obj":"LitCovid-PubTator"},{"subj":"351","pred":"source","obj":"LitCovid-PubTator"},{"subj":"352","pred":"source","obj":"LitCovid-PubTator"},{"subj":"353","pred":"source","obj":"LitCovid-PubTator"},{"subj":"354","pred":"source","obj":"LitCovid-PubTator"},{"subj":"355","pred":"source","obj":"LitCovid-PubTator"},{"subj":"356","pred":"source","obj":"LitCovid-PubTator"},{"subj":"357","pred":"source","obj":"LitCovid-PubTator"},{"subj":"358","pred":"source","obj":"LitCovid-PubTator"},{"subj":"359","pred":"source","obj":"LitCovid-PubTator"},{"subj":"360","pred":"source","obj":"LitCovid-PubTator"},{"subj":"361","pred":"source","obj":"LitCovid-PubTator"},{"subj":"362","pred":"source","obj":"LitCovid-PubTator"},{"subj":"363","pred":"source","obj":"LitCovid-PubTator"},{"subj":"364","pred":"source","obj":"LitCovid-PubTator"},{"subj":"365","pred":"source","obj":"LitCovid-PubTator"},{"subj":"366","pred":"source","obj":"LitCovid-PubTator"},{"subj":"367","pred":"source","obj":"LitCovid-PubTator"},{"subj":"368","pred":"source","obj":"LitCovid-PubTator"},{"subj":"369","pred":"source","obj":"LitCovid-PubTator"},{"subj":"370","pred":"source","obj":"LitCovid-PubTator"},{"subj":"371","pred":"source","obj":"LitCovid-PubTator"},{"subj":"372","pred":"source","obj":"LitCovid-PubTator"},{"subj":"373","pred":"source","obj":"LitCovid-PubTator"},{"subj":"374","pred":"source","obj":"LitCovid-PubTator"},{"subj":"375","pred":"source","obj":"LitCovid-PubTator"},{"subj":"376","pred":"source","obj":"LitCovid-PubTator"},{"subj":"377","pred":"source","obj":"LitCovid-PubTator"},{"subj":"378","pred":"source","obj":"LitCovid-PubTator"},{"subj":"379","pred":"source","obj":"LitCovid-PubTator"},{"subj":"380","pred":"source","obj":"LitCovid-PubTator"},{"subj":"381","pred":"source","obj":"LitCovid-PubTator"},{"subj":"382","pred":"source","obj":"LitCovid-PubTator"},{"subj":"383","pred":"source","obj":"LitCovid-PubTator"},{"subj":"384","pred":"source","obj":"LitCovid-PubTator"},{"subj":"385","pred":"source","obj":"LitCovid-PubTator"},{"subj":"386","pred":"source","obj":"LitCovid-PubTator"},{"subj":"387","pred":"source","obj":"LitCovid-PubTator"},{"subj":"388","pred":"source","obj":"LitCovid-PubTator"},{"subj":"389","pred":"source","obj":"LitCovid-PubTator"},{"subj":"390","pred":"source","obj":"LitCovid-PubTator"},{"subj":"391","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T61","span":{"begin":126,"end":130},"obj":"Body_part"},{"id":"T62","span":{"begin":156,"end":161},"obj":"Body_part"},{"id":"T63","span":{"begin":310,"end":315},"obj":"Body_part"},{"id":"T64","span":{"begin":428,"end":433},"obj":"Body_part"},{"id":"T65","span":{"begin":512,"end":517},"obj":"Body_part"},{"id":"T66","span":{"begin":721,"end":725},"obj":"Body_part"},{"id":"T67","span":{"begin":773,"end":777},"obj":"Body_part"},{"id":"T68","span":{"begin":800,"end":807},"obj":"Body_part"},{"id":"T69","span":{"begin":837,"end":842},"obj":"Body_part"},{"id":"T70","span":{"begin":893,"end":898},"obj":"Body_part"},{"id":"T71","span":{"begin":943,"end":950},"obj":"Body_part"},{"id":"T72","span":{"begin":971,"end":976},"obj":"Body_part"},{"id":"T73","span":{"begin":1029,"end":1034},"obj":"Body_part"},{"id":"T74","span":{"begin":1081,"end":1088},"obj":"Body_part"},{"id":"T75","span":{"begin":1116,"end":1121},"obj":"Body_part"},{"id":"T76","span":{"begin":1182,"end":1187},"obj":"Body_part"},{"id":"T77","span":{"begin":1226,"end":1229},"obj":"Body_part"},{"id":"T78","span":{"begin":1260,"end":1267},"obj":"Body_part"},{"id":"T79","span":{"begin":1278,"end":1283},"obj":"Body_part"},{"id":"T80","span":{"begin":1315,"end":1320},"obj":"Body_part"},{"id":"T81","span":{"begin":1489,"end":1493},"obj":"Body_part"},{"id":"T82","span":{"begin":1534,"end":1539},"obj":"Body_part"},{"id":"T83","span":{"begin":1556,"end":1563},"obj":"Body_part"},{"id":"T84","span":{"begin":1589,"end":1596},"obj":"Body_part"},{"id":"T85","span":{"begin":1700,"end":1703},"obj":"Body_part"},{"id":"T86","span":{"begin":1704,"end":1712},"obj":"Body_part"},{"id":"T87","span":{"begin":1763,"end":1771},"obj":"Body_part"},{"id":"T88","span":{"begin":1820,"end":1828},"obj":"Body_part"},{"id":"T89","span":{"begin":1866,"end":1873},"obj":"Body_part"},{"id":"T90","span":{"begin":1966,"end":1971},"obj":"Body_part"},{"id":"T91","span":{"begin":2149,"end":2156},"obj":"Body_part"},{"id":"T92","span":{"begin":2321,"end":2329},"obj":"Body_part"},{"id":"T93","span":{"begin":2384,"end":2391},"obj":"Body_part"},{"id":"T94","span":{"begin":2563,"end":2570},"obj":"Body_part"},{"id":"T95","span":{"begin":2629,"end":2636},"obj":"Body_part"},{"id":"T96","span":{"begin":2717,"end":2724},"obj":"Body_part"},{"id":"T97","span":{"begin":2747,"end":2752},"obj":"Body_part"},{"id":"T98","span":{"begin":2803,"end":2808},"obj":"Body_part"},{"id":"T99","span":{"begin":2902,"end":2909},"obj":"Body_part"},{"id":"T100","span":{"begin":2920,"end":2925},"obj":"Body_part"},{"id":"T101","span":{"begin":2957,"end":2962},"obj":"Body_part"}],"attributes":[{"id":"A61","pred":"fma_id","subj":"T61","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A62","pred":"fma_id","subj":"T62","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A63","pred":"fma_id","subj":"T63","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A64","pred":"fma_id","subj":"T64","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A65","pred":"fma_id","subj":"T65","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A66","pred":"fma_id","subj":"T66","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A67","pred":"fma_id","subj":"T67","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A68","pred":"fma_id","subj":"T68","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A69","pred":"fma_id","subj":"T69","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A70","pred":"fma_id","subj":"T70","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A71","pred":"fma_id","subj":"T71","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A72","pred":"fma_id","subj":"T72","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A73","pred":"fma_id","subj":"T73","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A74","pred":"fma_id","subj":"T74","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A75","pred":"fma_id","subj":"T75","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A76","pred":"fma_id","subj":"T76","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A77","pred":"fma_id","subj":"T77","obj":"http://purl.org/sig/ont/fma/fma62872"},{"id":"A78","pred":"fma_id","subj":"T78","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A79","pred":"fma_id","subj":"T79","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A80","pred":"fma_id","subj":"T80","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A81","pred":"fma_id","subj":"T81","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A82","pred":"fma_id","subj":"T82","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A83","pred":"fma_id","subj":"T83","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A84","pred":"fma_id","subj":"T84","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A85","pred":"fma_id","subj":"T85","obj":"http://purl.org/sig/ont/fma/fma62872"},{"id":"A86","pred":"fma_id","subj":"T86","obj":"http://purl.org/sig/ont/fma/fma62871"},{"id":"A87","pred":"fma_id","subj":"T87","obj":"http://purl.org/sig/ont/fma/fma62871"},{"id":"A88","pred":"fma_id","subj":"T88","obj":"http://purl.org/sig/ont/fma/fma62871"},{"id":"A89","pred":"fma_id","subj":"T89","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A90","pred":"fma_id","subj":"T90","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A91","pred":"fma_id","subj":"T91","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A92","pred":"fma_id","subj":"T92","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A93","pred":"fma_id","subj":"T93","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A94","pred":"fma_id","subj":"T94","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A95","pred":"fma_id","subj":"T95","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A96","pred":"fma_id","subj":"T96","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A97","pred":"fma_id","subj":"T97","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A98","pred":"fma_id","subj":"T98","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A99","pred":"fma_id","subj":"T99","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A100","pred":"fma_id","subj":"T100","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A101","pred":"fma_id","subj":"T101","obj":"http://purl.org/sig/ont/fma/fma68646"},{"subj":"T61","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T62","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T63","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T64","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T65","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T66","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T67","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T68","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T69","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T70","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T71","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T72","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T73","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T74","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T75","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T76","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T77","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T78","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T79","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T80","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T81","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T82","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T83","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T84","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T85","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T86","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T87","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T88","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T89","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T90","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T91","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T92","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T93","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T94","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T95","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T96","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T97","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T98","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T99","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T100","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T101","pred":"source","obj":"LitCovid-PD-FMA-UBERON"}]},{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T1","span":{"begin":2042,"end":2047},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"uberon_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/UBERON_0002542"},{"subj":"T1","pred":"source","obj":"LitCovid-PD-UBERON"}]},{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T178","span":{"begin":20,"end":28},"obj":"Disease"},{"id":"T179","span":{"begin":20,"end":24},"obj":"Disease"},{"id":"T180","span":{"begin":695,"end":703},"obj":"Disease"},{"id":"T181","span":{"begin":695,"end":699},"obj":"Disease"},{"id":"T182","span":{"begin":785,"end":793},"obj":"Disease"},{"id":"T183","span":{"begin":785,"end":789},"obj":"Disease"},{"id":"T184","span":{"begin":930,"end":938},"obj":"Disease"},{"id":"T185","span":{"begin":930,"end":934},"obj":"Disease"},{"id":"T186","span":{"begin":1463,"end":1471},"obj":"Disease"},{"id":"T187","span":{"begin":1463,"end":1467},"obj":"Disease"},{"id":"T188","span":{"begin":1541,"end":1549},"obj":"Disease"},{"id":"T189","span":{"begin":1541,"end":1545},"obj":"Disease"},{"id":"T190","span":{"begin":1576,"end":1584},"obj":"Disease"},{"id":"T191","span":{"begin":1576,"end":1580},"obj":"Disease"},{"id":"T192","span":{"begin":2134,"end":2142},"obj":"Disease"},{"id":"T193","span":{"begin":2134,"end":2138},"obj":"Disease"},{"id":"T194","span":{"begin":2205,"end":2213},"obj":"Disease"},{"id":"T195","span":{"begin":2205,"end":2209},"obj":"Disease"},{"id":"T196","span":{"begin":2291,"end":2299},"obj":"Disease"},{"id":"T197","span":{"begin":2291,"end":2295},"obj":"Disease"},{"id":"T198","span":{"begin":2508,"end":2516},"obj":"Disease"},{"id":"T199","span":{"begin":2508,"end":2512},"obj":"Disease"},{"id":"T200","span":{"begin":2534,"end":2542},"obj":"Disease"},{"id":"T201","span":{"begin":2534,"end":2538},"obj":"Disease"},{"id":"T202","span":{"begin":2702,"end":2710},"obj":"Disease"},{"id":"T203","span":{"begin":2702,"end":2706},"obj":"Disease"},{"id":"T204","span":{"begin":2774,"end":2782},"obj":"Disease"},{"id":"T205","span":{"begin":2774,"end":2778},"obj":"Disease"}],"attributes":[{"id":"A178","pred":"mondo_id","subj":"T178","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A179","pred":"mondo_id","subj":"T179","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A180","pred":"mondo_id","subj":"T180","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A181","pred":"mondo_id","subj":"T181","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A182","pred":"mondo_id","subj":"T182","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A183","pred":"mondo_id","subj":"T183","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A184","pred":"mondo_id","subj":"T184","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A185","pred":"mondo_id","subj":"T185","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A186","pred":"mondo_id","subj":"T186","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A187","pred":"mondo_id","subj":"T187","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A188","pred":"mondo_id","subj":"T188","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A189","pred":"mondo_id","subj":"T189","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A190","pred":"mondo_id","subj":"T190","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A191","pred":"mondo_id","subj":"T191","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A192","pred":"mondo_id","subj":"T192","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A193","pred":"mondo_id","subj":"T193","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A194","pred":"mondo_id","subj":"T194","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A195","pred":"mondo_id","subj":"T195","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A196","pred":"mondo_id","subj":"T196","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A197","pred":"mondo_id","subj":"T197","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A198","pred":"mondo_id","subj":"T198","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A199","pred":"mondo_id","subj":"T199","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A200","pred":"mondo_id","subj":"T200","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A201","pred":"mondo_id","subj":"T201","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A202","pred":"mondo_id","subj":"T202","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A203","pred":"mondo_id","subj":"T203","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A204","pred":"mondo_id","subj":"T204","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A205","pred":"mondo_id","subj":"T205","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"subj":"T178","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T179","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T180","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T181","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T182","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T183","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T184","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T185","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T186","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T187","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T188","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T189","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T190","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T191","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T192","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T193","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T194","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T195","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T196","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T197","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T198","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T199","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T200","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T201","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T202","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T203","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T204","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T205","pred":"source","obj":"LitCovid-PD-MONDO"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T140","span":{"begin":46,"end":51},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T141","span":{"begin":67,"end":68},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T142","span":{"begin":126,"end":136},"obj":"http://purl.obolibrary.org/obo/CLO_0000031"},{"id":"T143","span":{"begin":151,"end":155},"obj":"http://purl.obolibrary.org/obo/CLO_0050894"},{"id":"T144","span":{"begin":151,"end":155},"obj":"http://purl.obolibrary.org/obo/CLO_0051650"},{"id":"T145","span":{"begin":151,"end":155},"obj":"http://purl.obolibrary.org/obo/CLO_0052052"},{"id":"T146","span":{"begin":156,"end":161},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T147","span":{"begin":186,"end":191},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T148","span":{"begin":292,"end":296},"obj":"http://purl.obolibrary.org/obo/CLO_0050894"},{"id":"T149","span":{"begin":292,"end":296},"obj":"http://purl.obolibrary.org/obo/CLO_0051650"},{"id":"T150","span":{"begin":292,"end":296},"obj":"http://purl.obolibrary.org/obo/CLO_0052052"},{"id":"T151","span":{"begin":304,"end":308},"obj":"http://purl.obolibrary.org/obo/CLO_0050894"},{"id":"T152","span":{"begin":304,"end":308},"obj":"http://purl.obolibrary.org/obo/CLO_0051650"},{"id":"T153","span":{"begin":304,"end":308},"obj":"http://purl.obolibrary.org/obo/CLO_0052052"},{"id":"T154","span":{"begin":310,"end":315},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T155","span":{"begin":410,"end":414},"obj":"http://purl.obolibrary.org/obo/CLO_0050894"},{"id":"T156","span":{"begin":410,"end":414},"obj":"http://purl.obolibrary.org/obo/CLO_0051650"},{"id":"T157","span":{"begin":410,"end":414},"obj":"http://purl.obolibrary.org/obo/CLO_0052052"},{"id":"T158","span":{"begin":422,"end":426},"obj":"http://purl.obolibrary.org/obo/CLO_0050894"},{"id":"T159","span":{"begin":422,"end":426},"obj":"http://purl.obolibrary.org/obo/CLO_0051650"},{"id":"T160","span":{"begin":422,"end":426},"obj":"http://purl.obolibrary.org/obo/CLO_0052052"},{"id":"T161","span":{"begin":428,"end":433},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T162","span":{"begin":512,"end":517},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T163","span":{"begin":663,"end":664},"obj":"http://purl.obolibrary.org/obo/CLO_0001021"},{"id":"T164","span":{"begin":721,"end":725},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T165","span":{"begin":761,"end":765},"obj":"http://purl.obolibrary.org/obo/CLO_0050894"},{"id":"T166","span":{"begin":761,"end":765},"obj":"http://purl.obolibrary.org/obo/CLO_0051650"},{"id":"T167","span":{"begin":761,"end":765},"obj":"http://purl.obolibrary.org/obo/CLO_0052052"},{"id":"T168","span":{"begin":773,"end":783},"obj":"http://purl.obolibrary.org/obo/CLO_0000031"},{"id":"T169","span":{"begin":832,"end":836},"obj":"http://purl.obolibrary.org/obo/CLO_0050894"},{"id":"T170","span":{"begin":832,"end":836},"obj":"http://purl.obolibrary.org/obo/CLO_0051650"},{"id":"T171","span":{"begin":832,"end":836},"obj":"http://purl.obolibrary.org/obo/CLO_0052052"},{"id":"T172","span":{"begin":837,"end":842},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T173","span":{"begin":844,"end":845},"obj":"http://purl.obolibrary.org/obo/CLO_0001021"},{"id":"T174","span":{"begin":888,"end":892},"obj":"http://purl.obolibrary.org/obo/CLO_0050894"},{"id":"T175","span":{"begin":888,"end":892},"obj":"http://purl.obolibrary.org/obo/CLO_0051650"},{"id":"T176","span":{"begin":888,"end":892},"obj":"http://purl.obolibrary.org/obo/CLO_0052052"},{"id":"T177","span":{"begin":893,"end":898},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T178","span":{"begin":966,"end":970},"obj":"http://purl.obolibrary.org/obo/CLO_0050894"},{"id":"T179","span":{"begin":966,"end":970},"obj":"http://purl.obolibrary.org/obo/CLO_0051650"},{"id":"T180","span":{"begin":966,"end":970},"obj":"http://purl.obolibrary.org/obo/CLO_0052052"},{"id":"T181","span":{"begin":971,"end":976},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T182","span":{"begin":978,"end":979},"obj":"http://purl.obolibrary.org/obo/CLO_0001021"},{"id":"T183","span":{"begin":1024,"end":1028},"obj":"http://purl.obolibrary.org/obo/CLO_0050894"},{"id":"T184","span":{"begin":1024,"end":1028},"obj":"http://purl.obolibrary.org/obo/CLO_0051650"},{"id":"T185","span":{"begin":1024,"end":1028},"obj":"http://purl.obolibrary.org/obo/CLO_0052052"},{"id":"T186","span":{"begin":1029,"end":1034},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T187","span":{"begin":1111,"end":1115},"obj":"http://purl.obolibrary.org/obo/CLO_0050894"},{"id":"T188","span":{"begin":1111,"end":1115},"obj":"http://purl.obolibrary.org/obo/CLO_0051650"},{"id":"T189","span":{"begin":1111,"end":1115},"obj":"http://purl.obolibrary.org/obo/CLO_0052052"},{"id":"T190","span":{"begin":1116,"end":1121},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T191","span":{"begin":1123,"end":1124},"obj":"http://purl.obolibrary.org/obo/CLO_0001021"},{"id":"T192","span":{"begin":1177,"end":1181},"obj":"http://purl.obolibrary.org/obo/CLO_0050894"},{"id":"T193","span":{"begin":1177,"end":1181},"obj":"http://purl.obolibrary.org/obo/CLO_0051650"},{"id":"T194","span":{"begin":1177,"end":1181},"obj":"http://purl.obolibrary.org/obo/CLO_0052052"},{"id":"T195","span":{"begin":1182,"end":1187},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T196","span":{"begin":1220,"end":1229},"obj":"http://purl.obolibrary.org/obo/CLO_0053695"},{"id":"T197","span":{"begin":1230,"end":1232},"obj":"http://purl.obolibrary.org/obo/CLO_0052676"},{"id":"T198","span":{"begin":1239,"end":1241},"obj":"http://purl.obolibrary.org/obo/CLO_0052676"},{"id":"T199","span":{"begin":1278,"end":1283},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T200","span":{"begin":1315,"end":1320},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T201","span":{"begin":1363,"end":1364},"obj":"http://purl.obolibrary.org/obo/CLO_0001021"},{"id":"T202","span":{"begin":1489,"end":1493},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T203","span":{"begin":1529,"end":1533},"obj":"http://purl.obolibrary.org/obo/CLO_0050894"},{"id":"T204","span":{"begin":1529,"end":1533},"obj":"http://purl.obolibrary.org/obo/CLO_0051650"},{"id":"T205","span":{"begin":1529,"end":1533},"obj":"http://purl.obolibrary.org/obo/CLO_0052052"},{"id":"T206","span":{"begin":1534,"end":1539},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T207","span":{"begin":1635,"end":1636},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T208","span":{"begin":1676,"end":1683},"obj":"http://purl.obolibrary.org/obo/CLO_0007225"},{"id":"T209","span":{"begin":1684,"end":1688},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9925"},{"id":"T210","span":{"begin":1694,"end":1703},"obj":"http://purl.obolibrary.org/obo/CLO_0053695"},{"id":"T211","span":{"begin":1745,"end":1746},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T212","span":{"begin":1747,"end":1751},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9925"},{"id":"T213","span":{"begin":1802,"end":1809},"obj":"http://purl.obolibrary.org/obo/CLO_0007225"},{"id":"T214","span":{"begin":1815,"end":1819},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9925"},{"id":"T215","span":{"begin":1830,"end":1837},"obj":"http://purl.obolibrary.org/obo/CLO_0008776"},{"id":"T216","span":{"begin":1830,"end":1837},"obj":"http://purl.obolibrary.org/obo/CLO_0008777"},{"id":"T217","span":{"begin":1844,"end":1846},"obj":"http://purl.obolibrary.org/obo/CLO_0052676"},{"id":"T218","span":{"begin":1961,"end":1965},"obj":"http://purl.obolibrary.org/obo/CLO_0050894"},{"id":"T219","span":{"begin":1961,"end":1965},"obj":"http://purl.obolibrary.org/obo/CLO_0051650"},{"id":"T220","span":{"begin":1961,"end":1965},"obj":"http://purl.obolibrary.org/obo/CLO_0052052"},{"id":"T221","span":{"begin":1966,"end":1971},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T222","span":{"begin":2363,"end":2369},"obj":"http://purl.obolibrary.org/obo/UBERON_0000473"},{"id":"T223","span":{"begin":2742,"end":2746},"obj":"http://purl.obolibrary.org/obo/CLO_0050894"},{"id":"T224","span":{"begin":2742,"end":2746},"obj":"http://purl.obolibrary.org/obo/CLO_0051650"},{"id":"T225","span":{"begin":2742,"end":2746},"obj":"http://purl.obolibrary.org/obo/CLO_0052052"},{"id":"T226","span":{"begin":2747,"end":2752},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T227","span":{"begin":2798,"end":2802},"obj":"http://purl.obolibrary.org/obo/CLO_0050894"},{"id":"T228","span":{"begin":2798,"end":2802},"obj":"http://purl.obolibrary.org/obo/CLO_0051650"},{"id":"T229","span":{"begin":2798,"end":2802},"obj":"http://purl.obolibrary.org/obo/CLO_0052052"},{"id":"T230","span":{"begin":2803,"end":2808},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T231","span":{"begin":2920,"end":2925},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T232","span":{"begin":2957,"end":2962},"obj":"http://purl.obolibrary.org/obo/GO_0005623"}],"attributes":[{"subj":"T140","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T141","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T142","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T143","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T144","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T145","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T146","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T147","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T148","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T149","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T150","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T151","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T152","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T153","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T154","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T155","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T156","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T157","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T158","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T159","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T160","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T161","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T162","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T163","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T164","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T165","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T166","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T167","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T168","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T169","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T170","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T171","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T172","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T173","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T174","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T175","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T176","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T177","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T178","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T179","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T180","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T181","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T182","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T183","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T184","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T185","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T186","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T187","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T188","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T189","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T190","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T191","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T192","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T193","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T194","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T195","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T196","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T197","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T198","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T199","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T200","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T201","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T202","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T203","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T204","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T205","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T206","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T207","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T208","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T209","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T210","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T211","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T212","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T213","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T214","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T215","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T216","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T217","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T218","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T219","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T220","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T221","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T222","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T223","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T224","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T225","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T226","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T227","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T228","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T229","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T230","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T231","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T232","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T47","span":{"begin":800,"end":807},"obj":"Chemical"},{"id":"T48","span":{"begin":943,"end":950},"obj":"Chemical"},{"id":"T49","span":{"begin":1081,"end":1088},"obj":"Chemical"},{"id":"T50","span":{"begin":1260,"end":1267},"obj":"Chemical"},{"id":"T51","span":{"begin":1556,"end":1563},"obj":"Chemical"},{"id":"T52","span":{"begin":1589,"end":1596},"obj":"Chemical"},{"id":"T53","span":{"begin":1671,"end":1675},"obj":"Chemical"},{"id":"T54","span":{"begin":1792,"end":1797},"obj":"Chemical"},{"id":"T55","span":{"begin":1866,"end":1873},"obj":"Chemical"},{"id":"T56","span":{"begin":2015,"end":2027},"obj":"Chemical"},{"id":"T57","span":{"begin":2029,"end":2033},"obj":"Chemical"},{"id":"T58","span":{"begin":2149,"end":2156},"obj":"Chemical"},{"id":"T59","span":{"begin":2321,"end":2329},"obj":"Chemical"},{"id":"T60","span":{"begin":2384,"end":2391},"obj":"Chemical"},{"id":"T61","span":{"begin":2563,"end":2570},"obj":"Chemical"},{"id":"T62","span":{"begin":2629,"end":2636},"obj":"Chemical"},{"id":"T63","span":{"begin":2717,"end":2724},"obj":"Chemical"},{"id":"T64","span":{"begin":2902,"end":2909},"obj":"Chemical"}],"attributes":[{"id":"A47","pred":"chebi_id","subj":"T47","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A48","pred":"chebi_id","subj":"T48","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A49","pred":"chebi_id","subj":"T49","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A50","pred":"chebi_id","subj":"T50","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A51","pred":"chebi_id","subj":"T51","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A52","pred":"chebi_id","subj":"T52","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A53","pred":"chebi_id","subj":"T53","obj":"http://purl.obolibrary.org/obo/CHEBI_37926"},{"id":"A54","pred":"chebi_id","subj":"T54","obj":"http://purl.obolibrary.org/obo/CHEBI_24061"},{"id":"A55","pred":"chebi_id","subj":"T55","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A56","pred":"chebi_id","subj":"T56","obj":"http://purl.obolibrary.org/obo/CHEBI_48559"},{"id":"A57","pred":"chebi_id","subj":"T57","obj":"http://purl.obolibrary.org/obo/CHEBI_51231"},{"id":"A58","pred":"chebi_id","subj":"T58","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A59","pred":"chebi_id","subj":"T59","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A60","pred":"chebi_id","subj":"T60","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A61","pred":"chebi_id","subj":"T61","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A62","pred":"chebi_id","subj":"T62","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A63","pred":"chebi_id","subj":"T63","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A64","pred":"chebi_id","subj":"T64","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"subj":"T47","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T48","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T49","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T50","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T51","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T52","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T53","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T54","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T55","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T56","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T57","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T58","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T59","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T60","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T61","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T62","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T63","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T64","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T51","span":{"begin":0,"end":496},"obj":"Sentence"},{"id":"T52","span":{"begin":497,"end":554},"obj":"Sentence"},{"id":"T53","span":{"begin":555,"end":784},"obj":"Sentence"},{"id":"T54","span":{"begin":785,"end":929},"obj":"Sentence"},{"id":"T55","span":{"begin":930,"end":1067},"obj":"Sentence"},{"id":"T56","span":{"begin":1068,"end":1219},"obj":"Sentence"},{"id":"T57","span":{"begin":1220,"end":1369},"obj":"Sentence"},{"id":"T58","span":{"begin":1370,"end":1540},"obj":"Sentence"},{"id":"T59","span":{"begin":1541,"end":1843},"obj":"Sentence"},{"id":"T60","span":{"begin":1844,"end":1972},"obj":"Sentence"},{"id":"T61","span":{"begin":1973,"end":2041},"obj":"Sentence"},{"id":"T62","span":{"begin":2042,"end":2052},"obj":"Sentence"},{"id":"T63","span":{"begin":2053,"end":2059},"obj":"Sentence"},{"id":"T64","span":{"begin":2060,"end":2200},"obj":"Sentence"},{"id":"T65","span":{"begin":2201,"end":2370},"obj":"Sentence"},{"id":"T66","span":{"begin":2371,"end":2392},"obj":"Sentence"},{"id":"T67","span":{"begin":2393,"end":2442},"obj":"Sentence"},{"id":"T68","span":{"begin":2443,"end":2762},"obj":"Sentence"},{"id":"T69","span":{"begin":2763,"end":3011},"obj":"Sentence"},{"id":"T70","span":{"begin":3012,"end":3145},"obj":"Sentence"},{"id":"T71","span":{"begin":3146,"end":3184},"obj":"Sentence"},{"id":"T72","span":{"begin":3185,"end":3244},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T51","pred":"source","obj":"LitCovid-sentences"},{"subj":"T52","pred":"source","obj":"LitCovid-sentences"},{"subj":"T53","pred":"source","obj":"LitCovid-sentences"},{"subj":"T54","pred":"source","obj":"LitCovid-sentences"},{"subj":"T55","pred":"source","obj":"LitCovid-sentences"},{"subj":"T56","pred":"source","obj":"LitCovid-sentences"},{"subj":"T57","pred":"source","obj":"LitCovid-sentences"},{"subj":"T58","pred":"source","obj":"LitCovid-sentences"},{"subj":"T59","pred":"source","obj":"LitCovid-sentences"},{"subj":"T60","pred":"source","obj":"LitCovid-sentences"},{"subj":"T61","pred":"source","obj":"LitCovid-sentences"},{"subj":"T62","pred":"source","obj":"LitCovid-sentences"},{"subj":"T63","pred":"source","obj":"LitCovid-sentences"},{"subj":"T64","pred":"source","obj":"LitCovid-sentences"},{"subj":"T65","pred":"source","obj":"LitCovid-sentences"},{"subj":"T66","pred":"source","obj":"LitCovid-sentences"},{"subj":"T67","pred":"source","obj":"LitCovid-sentences"},{"subj":"T68","pred":"source","obj":"LitCovid-sentences"},{"subj":"T69","pred":"source","obj":"LitCovid-sentences"},{"subj":"T70","pred":"source","obj":"LitCovid-sentences"},{"subj":"T71","pred":"source","obj":"LitCovid-sentences"},{"subj":"T72","pred":"source","obj":"LitCovid-sentences"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PubTator","color":"#93ec97","default":true},{"id":"LitCovid-PD-FMA-UBERON","color":"#ec93a9"},{"id":"LitCovid-PD-UBERON","color":"#93c3ec"},{"id":"LitCovid-PD-MONDO","color":"#ddec93"},{"id":"LitCovid-PD-CLO","color":"#e193ec"},{"id":"LitCovid-PD-CHEBI","color":"#93ecc7"},{"id":"LitCovid-sentences","color":"#ecad93"}]}]}}