
PMC:7091888 / 9890-13134
Annnotations
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
329 | 52-56 | Gene | denotes | ACE2 | Gene:59272 |
330 | 192-196 | Gene | denotes | ACE2 | Gene:59272 |
331 | 198-203 | Gene | denotes | hACE2 | Gene:59272 |
332 | 232-237 | Gene | denotes | hDPP4 | Gene:1803 |
333 | 298-308 | Gene | denotes | hACE2/293T | Gene:59272 |
334 | 331-336 | Gene | denotes | hACE2 | Gene:59272 |
335 | 360-365 | Gene | denotes | hDPP4 | Gene:1803 |
336 | 416-426 | Gene | denotes | hDPP4/293T | Gene:1803 |
337 | 449-454 | Gene | denotes | hDPP4 | Gene:1803 |
338 | 476-481 | Gene | denotes | hACE2 | Gene:59272 |
339 | 737-742 | Gene | denotes | hACE2 | Gene:59272 |
340 | 755-765 | Gene | denotes | hACE2/293T | Gene:59272 |
341 | 826-831 | Gene | denotes | hACE2 | Gene:59272 |
342 | 960-965 | Gene | denotes | hACE2 | Gene:59272 |
343 | 1105-1110 | Gene | denotes | hACE2 | Gene:59272 |
344 | 1505-1510 | Gene | denotes | hACE2 | Gene:59272 |
345 | 1523-1533 | Gene | denotes | hACE2/293T | Gene:59272 |
346 | 1722-1727 | Gene | denotes | hACE2 | Gene:59272 |
347 | 1757-1762 | Gene | denotes | hACE2 | Gene:59272 |
348 | 1890-1895 | Gene | denotes | hACE2 | Gene:59272 |
349 | 1905-1910 | Gene | denotes | hACE2 | Gene:59272 |
350 | 1955-1960 | Gene | denotes | hACE2 | Gene:59272 |
351 | 2168-2173 | Gene | denotes | hACE2 | Gene:59272 |
352 | 2557-2562 | Gene | denotes | hACE2 | Gene:59272 |
353 | 2623-2628 | Gene | denotes | hDPP4 | Gene:1803 |
354 | 2736-2741 | Gene | denotes | hACE2 | Gene:59272 |
355 | 2792-2797 | Gene | denotes | hACE2 | Gene:59272 |
356 | 20-30 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
357 | 46-51 | Species | denotes | human | Tax:9606 |
358 | 186-191 | Species | denotes | human | Tax:9606 |
359 | 695-705 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
360 | 785-795 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
361 | 930-938 | Species | denotes | SARS-CoV | Tax:694009 |
362 | 1463-1473 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
363 | 1541-1551 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
364 | 1576-1584 | Species | denotes | SARS-CoV | Tax:694009 |
365 | 2134-2144 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
366 | 2205-2215 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
367 | 2291-2299 | Species | denotes | SARS-CoV | Tax:694009 |
368 | 2308-2316 | Species | denotes | MERS-CoV | Tax:1335626 |
369 | 2508-2518 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
370 | 2534-2542 | Species | denotes | SARS-CoV | Tax:694009 |
371 | 2702-2712 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
372 | 2774-2784 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
373 | 1220-1225 | Species | denotes | Human | Tax:9606 |
374 | 1694-1699 | Species | denotes | human | Tax:9606 |
375 | 2239-2244 | Gene | denotes | hDPP4 | Gene:1803 |
376 | 1671-1675 | Chemical | denotes | FITC | MESH:D016650 |
377 | 1786-1801 | Chemical | denotes | Alexa-Fluor 647 | MESH:C569686 |
378 | 1998-2027 | Chemical | denotes | 4’,6-diamidino-2-phenylindole | MESH:C007293 |
379 | 2029-2033 | Chemical | denotes | DAPI | MESH:C007293 |
380 | 151-155 | CellLine | denotes | 293T | CVCL:0063 |
381 | 292-296 | CellLine | denotes | 293T | CVCL:0063 |
382 | 410-414 | CellLine | denotes | 293T | CVCL:0063 |
383 | 832-836 | CellLine | denotes | 293T | CVCL:0063 |
384 | 888-892 | CellLine | denotes | 293T | CVCL:0063 |
385 | 966-970 | CellLine | denotes | 293T | CVCL:0063 |
386 | 1024-1028 | CellLine | denotes | 293T | CVCL:0063 |
387 | 1111-1115 | CellLine | denotes | 293T | CVCL:0063 |
388 | 1177-1181 | CellLine | denotes | 293T | CVCL:0063 |
389 | 1961-1965 | CellLine | denotes | 293T | CVCL:0063 |
390 | 2742-2746 | CellLine | denotes | 293T | CVCL:0063 |
391 | 2798-2802 | CellLine | denotes | 293T | CVCL:0063 |
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T61 | 126-130 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T62 | 156-161 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T63 | 310-315 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T64 | 428-433 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T65 | 512-517 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T66 | 721-725 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T67 | 773-777 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T68 | 800-807 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T69 | 837-842 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T70 | 893-898 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T71 | 943-950 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T72 | 971-976 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T73 | 1029-1034 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T74 | 1081-1088 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T75 | 1116-1121 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T76 | 1182-1187 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T77 | 1226-1229 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
T78 | 1260-1267 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T79 | 1278-1283 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T80 | 1315-1320 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T81 | 1489-1493 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T82 | 1534-1539 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T83 | 1556-1563 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T84 | 1589-1596 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T85 | 1700-1703 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
T86 | 1704-1712 | Body_part | denotes | antibody | http://purl.org/sig/ont/fma/fma62871 |
T87 | 1763-1771 | Body_part | denotes | antibody | http://purl.org/sig/ont/fma/fma62871 |
T88 | 1820-1828 | Body_part | denotes | antibody | http://purl.org/sig/ont/fma/fma62871 |
T89 | 1866-1873 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T90 | 1966-1971 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T91 | 2149-2156 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T92 | 2321-2329 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
T93 | 2384-2391 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T94 | 2563-2570 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T95 | 2629-2636 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T96 | 2717-2724 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T97 | 2747-2752 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T98 | 2803-2808 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T99 | 2902-2909 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T100 | 2920-2925 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T101 | 2957-2962 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
LitCovid-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T1 | 2042-2047 | Body_part | denotes | Scale | http://purl.obolibrary.org/obo/UBERON_0002542 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T178 | 20-28 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T179 | 20-24 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T180 | 695-703 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T181 | 695-699 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T182 | 785-793 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T183 | 785-789 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T184 | 930-938 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T185 | 930-934 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T186 | 1463-1471 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T187 | 1463-1467 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T188 | 1541-1549 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T189 | 1541-1545 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T190 | 1576-1584 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T191 | 1576-1580 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T192 | 2134-2142 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T193 | 2134-2138 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T194 | 2205-2213 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T195 | 2205-2209 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T196 | 2291-2299 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T197 | 2291-2295 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T198 | 2508-2516 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T199 | 2508-2512 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T200 | 2534-2542 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T201 | 2534-2538 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T202 | 2702-2710 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T203 | 2702-2706 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T204 | 2774-2782 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T205 | 2774-2778 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T140 | 46-51 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
T141 | 67-68 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T142 | 126-136 | http://purl.obolibrary.org/obo/CLO_0000031 | denotes | cell lines |
T143 | 151-155 | http://purl.obolibrary.org/obo/CLO_0050894 | denotes | 293T |
T144 | 151-155 | http://purl.obolibrary.org/obo/CLO_0051650 | denotes | 293T |
T145 | 151-155 | http://purl.obolibrary.org/obo/CLO_0052052 | denotes | 293T |
T146 | 156-161 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T147 | 186-191 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
T148 | 292-296 | http://purl.obolibrary.org/obo/CLO_0050894 | denotes | 293T |
T149 | 292-296 | http://purl.obolibrary.org/obo/CLO_0051650 | denotes | 293T |
T150 | 292-296 | http://purl.obolibrary.org/obo/CLO_0052052 | denotes | 293T |
T151 | 304-308 | http://purl.obolibrary.org/obo/CLO_0050894 | denotes | 293T |
T152 | 304-308 | http://purl.obolibrary.org/obo/CLO_0051650 | denotes | 293T |
T153 | 304-308 | http://purl.obolibrary.org/obo/CLO_0052052 | denotes | 293T |
T154 | 310-315 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T155 | 410-414 | http://purl.obolibrary.org/obo/CLO_0050894 | denotes | 293T |
T156 | 410-414 | http://purl.obolibrary.org/obo/CLO_0051650 | denotes | 293T |
T157 | 410-414 | http://purl.obolibrary.org/obo/CLO_0052052 | denotes | 293T |
T158 | 422-426 | http://purl.obolibrary.org/obo/CLO_0050894 | denotes | 293T |
T159 | 422-426 | http://purl.obolibrary.org/obo/CLO_0051650 | denotes | 293T |
T160 | 422-426 | http://purl.obolibrary.org/obo/CLO_0052052 | denotes | 293T |
T161 | 428-433 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T162 | 512-517 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T163 | 663-664 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | b |
T164 | 721-725 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
T165 | 761-765 | http://purl.obolibrary.org/obo/CLO_0050894 | denotes | 293T |
T166 | 761-765 | http://purl.obolibrary.org/obo/CLO_0051650 | denotes | 293T |
T167 | 761-765 | http://purl.obolibrary.org/obo/CLO_0052052 | denotes | 293T |
T168 | 773-783 | http://purl.obolibrary.org/obo/CLO_0000031 | denotes | cell lines |
T169 | 832-836 | http://purl.obolibrary.org/obo/CLO_0050894 | denotes | 293T |
T170 | 832-836 | http://purl.obolibrary.org/obo/CLO_0051650 | denotes | 293T |
T171 | 832-836 | http://purl.obolibrary.org/obo/CLO_0052052 | denotes | 293T |
T172 | 837-842 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T173 | 844-845 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | b |
T174 | 888-892 | http://purl.obolibrary.org/obo/CLO_0050894 | denotes | 293T |
T175 | 888-892 | http://purl.obolibrary.org/obo/CLO_0051650 | denotes | 293T |
T176 | 888-892 | http://purl.obolibrary.org/obo/CLO_0052052 | denotes | 293T |
T177 | 893-898 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T178 | 966-970 | http://purl.obolibrary.org/obo/CLO_0050894 | denotes | 293T |
T179 | 966-970 | http://purl.obolibrary.org/obo/CLO_0051650 | denotes | 293T |
T180 | 966-970 | http://purl.obolibrary.org/obo/CLO_0052052 | denotes | 293T |
T181 | 971-976 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T182 | 978-979 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | b |
T183 | 1024-1028 | http://purl.obolibrary.org/obo/CLO_0050894 | denotes | 293T |
T184 | 1024-1028 | http://purl.obolibrary.org/obo/CLO_0051650 | denotes | 293T |
T185 | 1024-1028 | http://purl.obolibrary.org/obo/CLO_0052052 | denotes | 293T |
T186 | 1029-1034 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T187 | 1111-1115 | http://purl.obolibrary.org/obo/CLO_0050894 | denotes | 293T |
T188 | 1111-1115 | http://purl.obolibrary.org/obo/CLO_0051650 | denotes | 293T |
T189 | 1111-1115 | http://purl.obolibrary.org/obo/CLO_0052052 | denotes | 293T |
T190 | 1116-1121 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T191 | 1123-1124 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | b |
T192 | 1177-1181 | http://purl.obolibrary.org/obo/CLO_0050894 | denotes | 293T |
T193 | 1177-1181 | http://purl.obolibrary.org/obo/CLO_0051650 | denotes | 293T |
T194 | 1177-1181 | http://purl.obolibrary.org/obo/CLO_0052052 | denotes | 293T |
T195 | 1182-1187 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T196 | 1220-1229 | http://purl.obolibrary.org/obo/CLO_0053695 | denotes | Human IgG |
T197 | 1230-1232 | http://purl.obolibrary.org/obo/CLO_0052676 | denotes | Fc |
T198 | 1239-1241 | http://purl.obolibrary.org/obo/CLO_0052676 | denotes | Fc |
T199 | 1278-1283 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T200 | 1315-1320 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T201 | 1363-1364 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | b |
T202 | 1489-1493 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
T203 | 1529-1533 | http://purl.obolibrary.org/obo/CLO_0050894 | denotes | 293T |
T204 | 1529-1533 | http://purl.obolibrary.org/obo/CLO_0051650 | denotes | 293T |
T205 | 1529-1533 | http://purl.obolibrary.org/obo/CLO_0052052 | denotes | 293T |
T206 | 1534-1539 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T207 | 1635-1636 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T208 | 1676-1683 | http://purl.obolibrary.org/obo/CLO_0007225 | denotes | labeled |
T209 | 1684-1688 | http://purl.obolibrary.org/obo/NCBITaxon_9925 | denotes | goat |
T210 | 1694-1703 | http://purl.obolibrary.org/obo/CLO_0053695 | denotes | human IgG |
T211 | 1745-1746 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T212 | 1747-1751 | http://purl.obolibrary.org/obo/NCBITaxon_9925 | denotes | goat |
T213 | 1802-1809 | http://purl.obolibrary.org/obo/CLO_0007225 | denotes | labeled |
T214 | 1815-1819 | http://purl.obolibrary.org/obo/NCBITaxon_9925 | denotes | goat |
T215 | 1830-1837 | http://purl.obolibrary.org/obo/CLO_0008776 | denotes | red) (1 |
T216 | 1830-1837 | http://purl.obolibrary.org/obo/CLO_0008777 | denotes | red) (1 |
T217 | 1844-1846 | http://purl.obolibrary.org/obo/CLO_0052676 | denotes | Fc |
T218 | 1961-1965 | http://purl.obolibrary.org/obo/CLO_0050894 | denotes | 293T |
T219 | 1961-1965 | http://purl.obolibrary.org/obo/CLO_0051650 | denotes | 293T |
T220 | 1961-1965 | http://purl.obolibrary.org/obo/CLO_0052052 | denotes | 293T |
T221 | 1966-1971 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T222 | 2363-2369 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | tested |
T223 | 2742-2746 | http://purl.obolibrary.org/obo/CLO_0050894 | denotes | 293T |
T224 | 2742-2746 | http://purl.obolibrary.org/obo/CLO_0051650 | denotes | 293T |
T225 | 2742-2746 | http://purl.obolibrary.org/obo/CLO_0052052 | denotes | 293T |
T226 | 2747-2752 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T227 | 2798-2802 | http://purl.obolibrary.org/obo/CLO_0050894 | denotes | 293T |
T228 | 2798-2802 | http://purl.obolibrary.org/obo/CLO_0051650 | denotes | 293T |
T229 | 2798-2802 | http://purl.obolibrary.org/obo/CLO_0052052 | denotes | 293T |
T230 | 2803-2808 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T231 | 2920-2925 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T232 | 2957-2962 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T47 | 800-807 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T48 | 943-950 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T49 | 1081-1088 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T50 | 1260-1267 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T51 | 1556-1563 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T52 | 1589-1596 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T53 | 1671-1675 | Chemical | denotes | FITC | http://purl.obolibrary.org/obo/CHEBI_37926 |
T54 | 1792-1797 | Chemical | denotes | Fluor | http://purl.obolibrary.org/obo/CHEBI_24061 |
T55 | 1866-1873 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T56 | 2015-2027 | Chemical | denotes | phenylindole | http://purl.obolibrary.org/obo/CHEBI_48559 |
T57 | 2029-2033 | Chemical | denotes | DAPI | http://purl.obolibrary.org/obo/CHEBI_51231 |
T58 | 2149-2156 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T59 | 2321-2329 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
T60 | 2384-2391 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T61 | 2563-2570 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T62 | 2629-2636 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T63 | 2717-2724 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T64 | 2902-2909 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T51 | 0-496 | Sentence | denotes | Fig. 2 Detection of SARS-CoV-2 RBD binding to human ACE2 receptor. a Flow cytometry analysis of receptor expression in stable cell lines. (left panel) 293T cells alone expressed neither human ACE2 (hACE2) receptor (orange line) nor hDPP4 receptor (cyan line); (middle panel) hACE2-expressing 293T (hACE2/293T) cells expressed only hACE2 (orange line), but not hDPP4 (cyan line); (right panel) hDPP4-expressing 293T (hDPP4/293T) cells expressed only hDPP4 (cyan line), but not hACE2 (orange line). |
T52 | 497-554 | Sentence | denotes | Mock-incubated cells (gray shading) were used as control. |
T53 | 555-784 | Sentence | denotes | Representative images and median fluorescence intensity (MFI) ± standard error (s.e.m.) were shown (n = 4). b, c Flow cytometry analysis of SARS-CoV-2 RBD binding to cell-associated hACE2 receptor in hACE2/293T stable cell lines. |
T54 | 785-929 | Sentence | denotes | SARS-CoV-2 RBD protein bound strongly to hACE2/293T cells (b (left panel, red line)), but not to hDPP4/293T cells (c (left panel, violet line)). |
T55 | 930-1067 | Sentence | denotes | SARS-CoV RBD protein bound to hACE2/293T cells (b (middle panel, red line)), but not to hDPP4/293T cells (c (middle panel, violet line)). |
T56 | 1068-1219 | Sentence | denotes | MERS-CoV RBD protein did not bind to hACE2/293T cells (b (right panel, red line)), but rather bound to hDPP4/293T cells (c (right panel, violet line)). |
T57 | 1220-1369 | Sentence | denotes | Human IgG Fc (hIgG-Fc, hereinafter hFc) protein-incubated cells (blue line) and mock-incubated cells (gray shading) were included as controls (b, c). |
T58 | 1370-1540 | Sentence | denotes | Representative images and MFI ± s.e.m. were shown (n = 4). d Immunofluorescence detection of SARS-CoV-2 RBD binding to cell-associated hACE2 receptor in hACE2/293T cells. |
T59 | 1541-1843 | Sentence | denotes | SARS-CoV-2 RBD protein (green) and SARS-CoV RBD protein (green), each of which was fused with a C-terminal hFc, were stained with FITC-labeled goat anti-human IgG antibody (1:500). hACE2 was stained with a goat-anti-hACE2 antibody (5 μg/ml) and Alexa-Fluor 647-labeled anti-goat antibody (red) (1:200). |
T60 | 1844-1972 | Sentence | denotes | Fc-fused MERS-CoV RBD protein did not bind to hACE2, so only hACE2 (red), but not RBD (green), was detected in hACE2/293T cells. |
T61 | 1973-2041 | Sentence | denotes | Nuclei were stained with 4’,6-diamidino-2-phenylindole (DAPI, blue). |
T62 | 2042-2052 | Sentence | denotes | Scale bar: |
T63 | 2053-2059 | Sentence | denotes | 10 μm. |
T64 | 2060-2200 | Sentence | denotes | Representative images are shown. e Detection of dose-dependent binding of SARS-CoV-2 RBD protein to soluble hACE2 (sACE2) receptor by ELISA. |
T65 | 2201-2370 | Sentence | denotes | The SARS-CoV-2 RBD binding to soluble hDPP4 (sDPP4) receptor (f), and the binding of both SARS-CoV RBD and MERS-CoV RBD proteins to sACE2 (e), or sDPP4 (f), were tested. |
T66 | 2371-2392 | Sentence | denotes | Control: hFc protein. |
T67 | 2393-2442 | Sentence | denotes | Data are presented as mean A450 ± s.e.m. (n = 4). |
T68 | 2443-2762 | Sentence | denotes | 50% effective dose (EC50) was calculated for the binding between SARS-CoV-2 RBD (black) or SARS-CoV RBD (red) and hACE2 protein (e, sACE2), or the binding between MERS-CoV RBD and hDPP4 protein (sDPP4, green) (f). g–i Flow cytometry analysis of inhibition of SARS-CoV-2 RBD protein binding to hACE2/293T cells by sACE2. |
T69 | 2763-3011 | Sentence | denotes | Binding of SARS-CoV-2 RBD to hACE2/293T cells (g, h, green line) was blocked by sACE2 (g, black line), but not by sDPP4 (h, red line). hFc protein-incubated cells (blue line) and mock-incubated cells (gray shading) were included as controls (g, h). |
T70 | 3012-3145 | Sentence | denotes | Representative images are shown. i The blocking ability of sACE2 or sDPP4, as described above, was expressed as MFI ± s.e.m. (n = 4). |
T71 | 3146-3184 | Sentence | denotes | Low MFI correlates with high blockage. |
T72 | 3185-3244 | Sentence | denotes | Experiments were repeated twice and yielded similar results |