PMC:7091888 / 5901-6821 JSONTXT

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    LitCovid-PubTator

    {"project":"LitCovid-PubTator","denotations":[{"id":"220","span":{"begin":185,"end":186},"obj":"Gene"},{"id":"221","span":{"begin":20,"end":30},"obj":"Species"},{"id":"222","span":{"begin":77,"end":87},"obj":"Species"},{"id":"223","span":{"begin":89,"end":97},"obj":"Species"},{"id":"224","span":{"begin":103,"end":111},"obj":"Species"},{"id":"225","span":{"begin":174,"end":184},"obj":"Species"},{"id":"226","span":{"begin":201,"end":209},"obj":"Species"},{"id":"227","span":{"begin":230,"end":238},"obj":"Species"},{"id":"228","span":{"begin":280,"end":290},"obj":"Species"},{"id":"229","span":{"begin":295,"end":303},"obj":"Species"},{"id":"230","span":{"begin":358,"end":368},"obj":"Species"},{"id":"231","span":{"begin":370,"end":378},"obj":"Species"},{"id":"232","span":{"begin":384,"end":392},"obj":"Species"},{"id":"233","span":{"begin":656,"end":666},"obj":"Species"},{"id":"234","span":{"begin":740,"end":748},"obj":"Species"},{"id":"235","span":{"begin":753,"end":761},"obj":"Species"},{"id":"236","span":{"begin":827,"end":831},"obj":"Species"},{"id":"237","span":{"begin":847,"end":855},"obj":"Species"},{"id":"238","span":{"begin":112,"end":117},"obj":"Gene"},{"id":"239","span":{"begin":607,"end":610},"obj":"Chemical"}],"attributes":[{"id":"A220","pred":"tao:has_database_id","subj":"220","obj":"Gene:43740568"},{"id":"A221","pred":"tao:has_database_id","subj":"221","obj":"Tax:2697049"},{"id":"A222","pred":"tao:has_database_id","subj":"222","obj":"Tax:2697049"},{"id":"A223","pred":"tao:has_database_id","subj":"223","obj":"Tax:694009"},{"id":"A224","pred":"tao:has_database_id","subj":"224","obj":"Tax:1335626"},{"id":"A225","pred":"tao:has_database_id","subj":"225","obj":"Tax:2697049"},{"id":"A226","pred":"tao:has_database_id","subj":"226","obj":"Tax:694009"},{"id":"A227","pred":"tao:has_database_id","subj":"227","obj":"Tax:1335626"},{"id":"A228","pred":"tao:has_database_id","subj":"228","obj":"Tax:2697049"},{"id":"A229","pred":"tao:has_database_id","subj":"229","obj":"Tax:694009"},{"id":"A230","pred":"tao:has_database_id","subj":"230","obj":"Tax:2697049"},{"id":"A231","pred":"tao:has_database_id","subj":"231","obj":"Tax:694009"},{"id":"A232","pred":"tao:has_database_id","subj":"232","obj":"Tax:1335626"},{"id":"A233","pred":"tao:has_database_id","subj":"233","obj":"Tax:2697049"},{"id":"A234","pred":"tao:has_database_id","subj":"234","obj":"Tax:694009"},{"id":"A235","pred":"tao:has_database_id","subj":"235","obj":"Tax:1335626"},{"id":"A236","pred":"tao:has_database_id","subj":"236","obj":"Tax:10090"},{"id":"A237","pred":"tao:has_database_id","subj":"237","obj":"Tax:694009"},{"id":"A238","pred":"tao:has_database_id","subj":"238","obj":"Gene:43740568"},{"id":"A239","pred":"tao:has_database_id","subj":"239","obj":"MESH:D012967"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Characterization of SARS-CoV-2 RBD. a Multiple sequence alignment of RBDs of SARS-CoV-2, SARS-CoV, and MERS-CoV spike (S) proteins. GenBank accession numbers are QHR63250.1 (SARS-CoV-2 S), AY278488.2 (SARS-CoV S), and AFS88936.1 (MERS-CoV S). Variable amino acid residues between SARS-CoV-2 and SARS-CoV are highlighted in cyan, and conserved residues among SARS-CoV-2, SARS-CoV, and MERS-CoV are highlighted in yellow. Asterisks represent fully conserved residues, colons represent highly conserved residues, and periods represent lowly conserved residues. The alignment was performed using Clustal Omega. SDS-PAGE (b) and Western blot (c, d) analysis of SARS-CoV-2 RBD. The protein molecular weight marker (kDa) is indicated on the left. SARS-CoV and MERS-CoV RBDs were included as controls. Antisera (1:3,000 dilution) from mice immunized with SARS-CoV RBD (c) and MERS-CoV RBD (d) were used for Western blot analysis"}

    LitCovid-PD-FMA-UBERON

    {"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T29","span":{"begin":122,"end":130},"obj":"Body_part"},{"id":"T30","span":{"begin":252,"end":262},"obj":"Body_part"},{"id":"T31","span":{"begin":676,"end":683},"obj":"Body_part"}],"attributes":[{"id":"A29","pred":"fma_id","subj":"T29","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A30","pred":"fma_id","subj":"T30","obj":"http://purl.org/sig/ont/fma/fma82739"},{"id":"A31","pred":"fma_id","subj":"T31","obj":"http://purl.org/sig/ont/fma/fma67257"}],"text":"Characterization of SARS-CoV-2 RBD. a Multiple sequence alignment of RBDs of SARS-CoV-2, SARS-CoV, and MERS-CoV spike (S) proteins. GenBank accession numbers are QHR63250.1 (SARS-CoV-2 S), AY278488.2 (SARS-CoV S), and AFS88936.1 (MERS-CoV S). Variable amino acid residues between SARS-CoV-2 and SARS-CoV are highlighted in cyan, and conserved residues among SARS-CoV-2, SARS-CoV, and MERS-CoV are highlighted in yellow. Asterisks represent fully conserved residues, colons represent highly conserved residues, and periods represent lowly conserved residues. The alignment was performed using Clustal Omega. SDS-PAGE (b) and Western blot (c, d) analysis of SARS-CoV-2 RBD. The protein molecular weight marker (kDa) is indicated on the left. SARS-CoV and MERS-CoV RBDs were included as controls. Antisera (1:3,000 dilution) from mice immunized with SARS-CoV RBD (c) and MERS-CoV RBD (d) were used for Western blot analysis"}

    LitCovid-PD-MONDO

    {"project":"LitCovid-PD-MONDO","denotations":[{"id":"T114","span":{"begin":20,"end":28},"obj":"Disease"},{"id":"T115","span":{"begin":20,"end":24},"obj":"Disease"},{"id":"T116","span":{"begin":77,"end":85},"obj":"Disease"},{"id":"T117","span":{"begin":77,"end":81},"obj":"Disease"},{"id":"T118","span":{"begin":89,"end":97},"obj":"Disease"},{"id":"T119","span":{"begin":89,"end":93},"obj":"Disease"},{"id":"T120","span":{"begin":174,"end":182},"obj":"Disease"},{"id":"T121","span":{"begin":174,"end":178},"obj":"Disease"},{"id":"T122","span":{"begin":201,"end":209},"obj":"Disease"},{"id":"T123","span":{"begin":201,"end":205},"obj":"Disease"},{"id":"T124","span":{"begin":280,"end":288},"obj":"Disease"},{"id":"T125","span":{"begin":280,"end":284},"obj":"Disease"},{"id":"T126","span":{"begin":295,"end":303},"obj":"Disease"},{"id":"T127","span":{"begin":295,"end":299},"obj":"Disease"},{"id":"T128","span":{"begin":358,"end":366},"obj":"Disease"},{"id":"T129","span":{"begin":358,"end":362},"obj":"Disease"},{"id":"T130","span":{"begin":370,"end":378},"obj":"Disease"},{"id":"T131","span":{"begin":370,"end":374},"obj":"Disease"},{"id":"T132","span":{"begin":656,"end":664},"obj":"Disease"},{"id":"T133","span":{"begin":656,"end":660},"obj":"Disease"},{"id":"T134","span":{"begin":740,"end":748},"obj":"Disease"},{"id":"T135","span":{"begin":740,"end":744},"obj":"Disease"},{"id":"T136","span":{"begin":847,"end":855},"obj":"Disease"},{"id":"T137","span":{"begin":847,"end":851},"obj":"Disease"}],"attributes":[{"id":"A114","pred":"mondo_id","subj":"T114","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A115","pred":"mondo_id","subj":"T115","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A116","pred":"mondo_id","subj":"T116","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A117","pred":"mondo_id","subj":"T117","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A118","pred":"mondo_id","subj":"T118","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A119","pred":"mondo_id","subj":"T119","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A120","pred":"mondo_id","subj":"T120","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A121","pred":"mondo_id","subj":"T121","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A122","pred":"mondo_id","subj":"T122","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A123","pred":"mondo_id","subj":"T123","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A124","pred":"mondo_id","subj":"T124","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A125","pred":"mondo_id","subj":"T125","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A126","pred":"mondo_id","subj":"T126","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A127","pred":"mondo_id","subj":"T127","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A128","pred":"mondo_id","subj":"T128","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A129","pred":"mondo_id","subj":"T129","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A130","pred":"mondo_id","subj":"T130","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A131","pred":"mondo_id","subj":"T131","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A132","pred":"mondo_id","subj":"T132","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A133","pred":"mondo_id","subj":"T133","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A134","pred":"mondo_id","subj":"T134","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A135","pred":"mondo_id","subj":"T135","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A136","pred":"mondo_id","subj":"T136","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A137","pred":"mondo_id","subj":"T137","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"Characterization of SARS-CoV-2 RBD. a Multiple sequence alignment of RBDs of SARS-CoV-2, SARS-CoV, and MERS-CoV spike (S) proteins. GenBank accession numbers are QHR63250.1 (SARS-CoV-2 S), AY278488.2 (SARS-CoV S), and AFS88936.1 (MERS-CoV S). Variable amino acid residues between SARS-CoV-2 and SARS-CoV are highlighted in cyan, and conserved residues among SARS-CoV-2, SARS-CoV, and MERS-CoV are highlighted in yellow. Asterisks represent fully conserved residues, colons represent highly conserved residues, and periods represent lowly conserved residues. The alignment was performed using Clustal Omega. SDS-PAGE (b) and Western blot (c, d) analysis of SARS-CoV-2 RBD. The protein molecular weight marker (kDa) is indicated on the left. SARS-CoV and MERS-CoV RBDs were included as controls. Antisera (1:3,000 dilution) from mice immunized with SARS-CoV RBD (c) and MERS-CoV RBD (d) were used for Western blot analysis"}

    LitCovid-PD-CLO

    {"project":"LitCovid-PD-CLO","denotations":[{"id":"T53","span":{"begin":36,"end":37},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T54","span":{"begin":252,"end":271},"obj":"http://purl.obolibrary.org/obo/CHEBI_33708"},{"id":"T55","span":{"begin":252,"end":271},"obj":"http://purl.obolibrary.org/obo/PR_000036907"},{"id":"T56","span":{"begin":466,"end":472},"obj":"http://purl.obolibrary.org/obo/UBERON_0001155"},{"id":"T57","span":{"begin":617,"end":618},"obj":"http://purl.obolibrary.org/obo/CLO_0001021"}],"text":"Characterization of SARS-CoV-2 RBD. a Multiple sequence alignment of RBDs of SARS-CoV-2, SARS-CoV, and MERS-CoV spike (S) proteins. GenBank accession numbers are QHR63250.1 (SARS-CoV-2 S), AY278488.2 (SARS-CoV S), and AFS88936.1 (MERS-CoV S). Variable amino acid residues between SARS-CoV-2 and SARS-CoV are highlighted in cyan, and conserved residues among SARS-CoV-2, SARS-CoV, and MERS-CoV are highlighted in yellow. Asterisks represent fully conserved residues, colons represent highly conserved residues, and periods represent lowly conserved residues. The alignment was performed using Clustal Omega. SDS-PAGE (b) and Western blot (c, d) analysis of SARS-CoV-2 RBD. The protein molecular weight marker (kDa) is indicated on the left. SARS-CoV and MERS-CoV RBDs were included as controls. Antisera (1:3,000 dilution) from mice immunized with SARS-CoV RBD (c) and MERS-CoV RBD (d) were used for Western blot analysis"}

    LitCovid-PD-CHEBI

    {"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T34","span":{"begin":122,"end":130},"obj":"Chemical"},{"id":"T35","span":{"begin":252,"end":262},"obj":"Chemical"},{"id":"T36","span":{"begin":252,"end":257},"obj":"Chemical"},{"id":"T37","span":{"begin":258,"end":262},"obj":"Chemical"},{"id":"T38","span":{"begin":607,"end":610},"obj":"Chemical"},{"id":"T39","span":{"begin":676,"end":683},"obj":"Chemical"}],"attributes":[{"id":"A34","pred":"chebi_id","subj":"T34","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A35","pred":"chebi_id","subj":"T35","obj":"http://purl.obolibrary.org/obo/CHEBI_33709"},{"id":"A36","pred":"chebi_id","subj":"T36","obj":"http://purl.obolibrary.org/obo/CHEBI_46882"},{"id":"A37","pred":"chebi_id","subj":"T37","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"},{"id":"A38","pred":"chebi_id","subj":"T38","obj":"http://purl.obolibrary.org/obo/CHEBI_8984"},{"id":"A39","pred":"chebi_id","subj":"T39","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"}],"text":"Characterization of SARS-CoV-2 RBD. a Multiple sequence alignment of RBDs of SARS-CoV-2, SARS-CoV, and MERS-CoV spike (S) proteins. GenBank accession numbers are QHR63250.1 (SARS-CoV-2 S), AY278488.2 (SARS-CoV S), and AFS88936.1 (MERS-CoV S). Variable amino acid residues between SARS-CoV-2 and SARS-CoV are highlighted in cyan, and conserved residues among SARS-CoV-2, SARS-CoV, and MERS-CoV are highlighted in yellow. Asterisks represent fully conserved residues, colons represent highly conserved residues, and periods represent lowly conserved residues. The alignment was performed using Clustal Omega. SDS-PAGE (b) and Western blot (c, d) analysis of SARS-CoV-2 RBD. The protein molecular weight marker (kDa) is indicated on the left. SARS-CoV and MERS-CoV RBDs were included as controls. Antisera (1:3,000 dilution) from mice immunized with SARS-CoV RBD (c) and MERS-CoV RBD (d) were used for Western blot analysis"}

    LitCovid-sentences

    {"project":"LitCovid-sentences","denotations":[{"id":"T23","span":{"begin":132,"end":242},"obj":"Sentence"},{"id":"T24","span":{"begin":243,"end":419},"obj":"Sentence"},{"id":"T25","span":{"begin":420,"end":557},"obj":"Sentence"},{"id":"T26","span":{"begin":558,"end":606},"obj":"Sentence"},{"id":"T27","span":{"begin":607,"end":671},"obj":"Sentence"},{"id":"T28","span":{"begin":672,"end":739},"obj":"Sentence"},{"id":"T29","span":{"begin":740,"end":793},"obj":"Sentence"},{"id":"T30","span":{"begin":794,"end":920},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Characterization of SARS-CoV-2 RBD. a Multiple sequence alignment of RBDs of SARS-CoV-2, SARS-CoV, and MERS-CoV spike (S) proteins. GenBank accession numbers are QHR63250.1 (SARS-CoV-2 S), AY278488.2 (SARS-CoV S), and AFS88936.1 (MERS-CoV S). Variable amino acid residues between SARS-CoV-2 and SARS-CoV are highlighted in cyan, and conserved residues among SARS-CoV-2, SARS-CoV, and MERS-CoV are highlighted in yellow. Asterisks represent fully conserved residues, colons represent highly conserved residues, and periods represent lowly conserved residues. The alignment was performed using Clustal Omega. SDS-PAGE (b) and Western blot (c, d) analysis of SARS-CoV-2 RBD. The protein molecular weight marker (kDa) is indicated on the left. SARS-CoV and MERS-CoV RBDs were included as controls. Antisera (1:3,000 dilution) from mice immunized with SARS-CoV RBD (c) and MERS-CoV RBD (d) were used for Western blot analysis"}