PMC:7091888 / 27411-28364
Annnotations
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 1099 | 519-524 | Gene | denotes | hACE2 | Gene:59272 |
| 1100 | 529-534 | Gene | denotes | hDPP4 | Gene:1803 |
| 1101 | 45-55 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 1102 | 120-128 | Species | denotes | SARS-CoV | Tax:694009 |
| 1103 | 133-141 | Species | denotes | MERS-CoV | Tax:1335626 |
| 1104 | 239-249 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 1105 | 251-259 | Species | denotes | SARS-CoV | Tax:694009 |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T222 | 60-67 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T223 | 165-172 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T224 | 334-338 | Body_part | denotes | milk | http://purl.org/sig/ont/fma/fma62100 |
| T225 | 399-406 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T226 | 492-499 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T227 | 549-557 | Body_part | denotes | antibody | http://purl.org/sig/ont/fma/fma62871 |
| T228 | 653-656 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
| T229 | 657-665 | Body_part | denotes | antibody | http://purl.org/sig/ont/fma/fma62871 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T4 | 334-338 | Body_part | denotes | milk | http://purl.obolibrary.org/obo/UBERON_0001913 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T474 | 45-53 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T475 | 45-49 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T476 | 120-128 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T477 | 120-124 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T478 | 239-247 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T479 | 239-243 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T480 | 251-259 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T481 | 251-255 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T480 | 300-304 | http://purl.obolibrary.org/obo/CLO_0001387 | denotes | 4 °C |
| T481 | 325-328 | http://purl.obolibrary.org/obo/UBERON_0001013 | denotes | fat |
| T482 | 544-548 | http://purl.obolibrary.org/obo/NCBITaxon_9925 | denotes | goat |
| T483 | 570-573 | http://purl.obolibrary.org/obo/CLO_0008693 | denotes | R&D |
| T484 | 570-573 | http://purl.obolibrary.org/obo/CLO_0008770 | denotes | R&D |
| T485 | 648-652 | http://purl.obolibrary.org/obo/NCBITaxon_9925 | denotes | goat |
| T486 | 818-820 | http://purl.obolibrary.org/obo/CLO_0009141 | denotes | St |
| T487 | 818-820 | http://purl.obolibrary.org/obo/CLO_0050980 | denotes | St |
| T488 | 829-831 | http://purl.obolibrary.org/obo/CLO_0007815 | denotes | MO |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T150 | 60-67 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T151 | 165-172 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T152 | 399-406 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T153 | 492-499 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T154 | 848-853 | Chemical | denotes | H2SO4 | http://purl.obolibrary.org/obo/CHEBI_26836 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T160 | 0-196 | Sentence | denotes | ELISA was performed to detect the binding of SARS-CoV-2 RBD protein to sACE2 receptor, as previously described.27,32,34 SARS-CoV and MERS-CoV RBDs, as well as sDPP4 protein, were used as controls. |
| T161 | 197-364 | Sentence | denotes | Briefly, ELISA plates were precoated with SARS-CoV-2, SARS-CoV, or MERS-CoV RBD (1 μg/ml) overnight at 4 °C and blocked with 2% fat-free milk in PBST for 2 h at 37 °C. |
| T162 | 365-462 | Sentence | denotes | Serially diluted sACE2, or sDPP4, protein was added to the plates and incubated for 2 h at 37 °C. |
| T163 | 463-719 | Sentence | denotes | After four washes, the bound protein was detected using hACE2- or hDPP4-specific goat antibody (0.5 μg/ml, R&D system) for 2 h at 37 °C, followed by incubation with HRP-conjugated anti-goat IgG antibody (1:5,000, Thermo Fisher Scientific) for 1 h at 37 °C. |
| T164 | 720-860 | Sentence | denotes | The reaction was visualized by addition of substrate 3,3’,5,5’-Tetramethylbenzidine (TMB) (Sigma, St. Louis, MO) and stopped by H2SO4 (1 N). |
| T165 | 861-953 | Sentence | denotes | The absorbance at 450 nm (A450) was measured by an ELISA plate reader (Tecan, San Jose, CA). |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32203189-23824801-19774545 | 114-116 | 23824801 | denotes | 32 |
| 32203189-24355931-19774546 | 117-119 | 24355931 | denotes | 34 |